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Protein

60S ribosomal protein L24

Gene

rpl24

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Plays an essential role in early embryonic development.1 Publication

GO - Molecular functioni

GO - Biological processi

  • assembly of large subunit precursor of preribosome Source: GO_Central
  • chordate embryonic development Source: ZFIN
  • ribosomal large subunit assembly Source: GO_Central
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L24
Gene namesi
Name:rpl24
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-020419-25. rpl24.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Disruption phenotypei

Embryos show various defects including smaller head and eyes.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001368711 – 15760S ribosomal protein L24Add BLAST157

Proteomic databases

PaxDbiQ8JGR4.
PRIDEiQ8JGR4.

Expressioni

Gene expression databases

BgeeiENSDARG00000015490.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000020358.

Structurei

3D structure databases

ProteinModelPortaliQ8JGR4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L24e family.Curated

Phylogenomic databases

eggNOGiKOG1722. Eukaryota.
COG2075. LUCA.
HOGENOMiHOG000184343.
HOVERGENiHBG001066.
InParanoidiQ8JGR4.
KOiK02896.
PhylomeDBiQ8JGR4.

Family and domain databases

CDDicd00472. Ribosomal_L24e_L24. 1 hit.
Gene3Di2.30.170.20. 1 hit.
InterProiIPR000988. Ribosomal_L24e-rel.
IPR023442. Ribosomal_L24e_CS.
IPR011017. TRASH_dom.
[Graphical view]
PANTHERiPTHR10792. PTHR10792. 1 hit.
PfamiPF01246. Ribosomal_L24e. 1 hit.
[Graphical view]
SMARTiSM00746. TRASH. 1 hit.
[Graphical view]
PROSITEiPS01073. RIBOSOMAL_L24E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8JGR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVELCSFSG YKIYPGHGRR YARVDGKVFQ FLNAKCESAF LSKRNPRQIN
60 70 80 90 100
WTVLYRRKHK KGQSEEVSKK RTRRAVKFQR AITGASLAEI LAKRNQKPEV
110 120 130 140 150
RKAQREQAIR AAKEAKKAKQ ATKKQTTQSS KAPAKSAQKQ KIAKPMKVSA

PRVGGKR
Length:157
Mass (Da):17,869
Last modified:October 1, 2002 - v1
Checksum:i9C36D392CA2E0B1F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti24V → I in AAH59530 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY099532 mRNA. Translation: AAM28220.1.
BC059530 mRNA. Translation: AAH59530.1.
RefSeqiNP_775342.2. NM_173235.3.
UniGeneiDr.1310.

Genome annotation databases

GeneIDi192301.
KEGGidre:192301.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY099532 mRNA. Translation: AAM28220.1.
BC059530 mRNA. Translation: AAH59530.1.
RefSeqiNP_775342.2. NM_173235.3.
UniGeneiDr.1310.

3D structure databases

ProteinModelPortaliQ8JGR4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000020358.

Proteomic databases

PaxDbiQ8JGR4.
PRIDEiQ8JGR4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi192301.
KEGGidre:192301.

Organism-specific databases

CTDi6152.
ZFINiZDB-GENE-020419-25. rpl24.

Phylogenomic databases

eggNOGiKOG1722. Eukaryota.
COG2075. LUCA.
HOGENOMiHOG000184343.
HOVERGENiHBG001066.
InParanoidiQ8JGR4.
KOiK02896.
PhylomeDBiQ8JGR4.

Miscellaneous databases

PROiQ8JGR4.

Gene expression databases

BgeeiENSDARG00000015490.

Family and domain databases

CDDicd00472. Ribosomal_L24e_L24. 1 hit.
Gene3Di2.30.170.20. 1 hit.
InterProiIPR000988. Ribosomal_L24e-rel.
IPR023442. Ribosomal_L24e_CS.
IPR011017. TRASH_dom.
[Graphical view]
PANTHERiPTHR10792. PTHR10792. 1 hit.
PfamiPF01246. Ribosomal_L24e. 1 hit.
[Graphical view]
SMARTiSM00746. TRASH. 1 hit.
[Graphical view]
PROSITEiPS01073. RIBOSOMAL_L24E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL24_DANRE
AccessioniPrimary (citable) accession number: Q8JGR4
Secondary accession number(s): Q6PBZ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: October 1, 2002
Last modified: October 5, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.