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Protein
Submitted name:

Casein kinase 1, alpha 1

Gene

csnk1a1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: ZFIN
  • protein kinase activity Source: ZFIN
  • protein serine/threonine kinase activity Source: ZFIN

GO - Biological processi

  • heart development Source: ZFIN
  • peptidyl-serine phosphorylation Source: ZFIN
  • protein phosphorylation Source: ZFIN

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-195253 Degradation of beta-catenin by the destruction complex
R-DRE-196299 Beta-catenin phosphorylation cascade
R-DRE-5610785 GLI3 is processed to GLI3R by the proteasome

Names & Taxonomyi

Protein namesi
Submitted name:
Casein kinase 1, alpha 1Imported
Submitted name:
Casein kinase 1alpha SImported
Gene namesi
Name:csnk1a1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 14

Organism-specific databases

ZFINiZDB-GENE-020419-19 csnk1a1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000052674

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 285Protein kinaseInterPro annotationAdd BLAST269

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119040
HOGENOMiHOG000182055
HOVERGENiHBG000176

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q8JG73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ
60 70 80 90 100
KARHPQLLYE SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL
110 120 130 140 150
FNFCSRRFTM KTVLMLADQM ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC
160 170 180 190 200
NKLFLIDFGL AKKYRDNRTR QHIPYREDKN LTGTARYASI NAHLGIEQSR
210 220 230 240 250
RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK MSTPVEVLCK
260 270 280 290 300
GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM
310 320 330
LKQKAAQQAA SSGGQGQQAQ TPTGKQTDKP KSNMKGF
Length:337
Mass (Da):38,881
Last modified:October 1, 2002 - v1
Checksum:iBA61D1AE33CAFAC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX088707 Genomic DNA No translation available.
AY116143 mRNA Translation: AAM76209.1
RefSeqiXP_009289365.1, XM_009291090.2
UniGeneiDr.132291

Genome annotation databases

EnsembliENSDART00000173351; ENSDARP00000142599; ENSDARG00000052674
GeneIDi192307

Similar proteinsi

Entry informationi

Entry nameiQ8JG73_DANRE
AccessioniPrimary (citable) accession number: Q8JG73
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 23, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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