Unreviewed, UniProtKB/TrEMBL Q8JG32 (Q8JG32_CHICK)

Names and origin

Protein names

Submitted name:
    Minibrain protein kinase EMBL CAD30635.1

Gene names

Name:

MNB EMBL CAD30635.1

Organism

Gallus gallus (Chicken) EMBL CAD30635.1

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	756 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW non-membrane spanning protein tyrosine kinase activity Inferred from electronic annotation. Source: Compara protein self-association Inferred from electronic annotation. Source: Compara protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8JG32-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 3D1832B63B396E48	FASTA	756	84,961
	10 20 30 40 50 60 MHTGGETSAC KPSSVRLAPS FSFHAAGLQM AGQMSHSHQQ YSDRRQQNIN DQQVSASSYT 70 80 90 100 110 120 DRIQQPLTNQ RRMPQTFRDP ATAPLRKLSV DLIKTYKHIN EVYYAKKKRR HQQGQGDDSS 130 140 150 160 170 180 HKKERKVYND GYDDDNYDYI VKNGEKWMDR YEIDSLIGKG SFGQVVKAYD RVEQEWVAIK 190 200 210 220 230 240 IIKNKKAFLN QAQIEVRLLE LMNKHDTEMK YYIVHLNRHF MFRNHLCLVF EMLSYNLYDL 250 260 270 280 290 300 LRNTNFRGVS LNLTRKFAQQ MCTALLFLAT PELSIIHCDL KPENILLCNP KRSAIKIVDF 310 320 330 340 350 360 GSSCQLGQRI YQYIQSRFYR SPEVLLGMPY DLAIDMWSLG CILVEMHTGE PLFSGANEVD 370 380 390 400 410 420 QMNKIVEVLG IPPAHILDQA PKARKFFEKL PDGTWNLKKT KDGKREYKPP GTRKLHNILG 430 440 450 460 470 480 VETGGPGGRR AGESGHTVAD YLKFKDLILR MLDYDPKTRI QPYYALQHSF FKKTADEGTN 490 500 510 520 530 540 TSNSVSTSPA MEQSQSSGTT SSTSSSSGGS SGTSNSGRAR SDPTHQHRHS GGHFTAAVQA 550 560 570 580 590 600 MDCETHSPQV RQQFPPPIGW TATEAPTQVT VENHPVQETT FHVTPQQQNA LHHHHGNSSH 610 620 630 640 650 660 HHHHHHHHHH HHGQQALGSR TRPRVYNSPT NSSSTQDSME VGHSHHSMTS LASSTTSSST 670 680 690 700 710 720 SSSSTGNQGN QAYQNRPVAA NTLDFGQNGA MDMNLTVYSN PRQETGIAGH PTYQFSANTG 730 740 750 PAHYMTEGHL AMRQGIDREE SPMTGVCVQQ SPVASS

References

[1]

"Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions." Hammerle B., Vera-Samper E., Speicher S., Arencibia R., Martinez S., Tejedor F.J. Dev. Biol. 246:259-273(2002) [PubMed: 12051815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL CAD30635.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ459381 mRNA. Translation: CAD30635.1.
IPI	IPI00574305.
RefSeq	NP_989881.1.
UniGene	Gga.146
3D structure databases
HSSP	HSSP built from PDB template 1PYX based on UniProtKB P49841.
SMR	Q8JG32. Positions 133-477.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8JG32.
Proteomic databases
PRIDE	Q8JG32.
Genome annotation databases
Ensembl	ENSGALT00000025866; ENSGALP00000025819; ENSGALG00000016053; Gallus gallus. [Genome view]
GeneID	395233.
KEGG	gga:395233.
Organism-specific databases
CTD	395233.
Phylogenomic databases
eggNOG	veNOG04490.
HOGENOM	HBG755340.
HOVERGEN	Q8JG32.
InParanoid	Q8JG32.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8JG32_CHICK

Accession

Primary (citable) accession number: Q8JG32

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	January 19, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)