Reviewed, UniProtKB/Swiss-Prot Q8JFR1 (LYG_CYPCA)

Names and origin

Protein names	Recommended name:     Lysozyme g     EC=3.2.1.17 Alternative name(s):     1,4-beta-N-acetylmuramidase
Organism	Cyprinus carpio (Common carp)
Taxonomic identifier	7962 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Cyprinus

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Sequence similarities	Belongs to the glycosyl hydrolase 23 family.

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Lysozyme g		PRO_0000193517
Sites
	Active site	73	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8JFR1-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 2B6D9346268EAB25	FASTA	185	20,381
	10 20 30 40 50 60 MAYIYGDTMK IDTTGASEAT AKQDKLTIKG VEAPKKLAEH DLARGEKYKN MITKVGKAKK 70 80 90 100 110 120 MDPAVIAAMI SRESRAGAVL KNGWEPAGNG FGLMQVDKRS HTPVGAWDSE QHVTQATEIL 130 140 150 160 170 180 IGFIKEIKVN FPKWTQEQCF KGGIAAYNKG VSRVTSYENI DVKTTGLDYS SDVVARAQWF RSKGY

References

[1]	"Molecular cloning of G type lysozyme cDNA in common carp (Cyprinus carpio L.)." Savan R., Aman A., Sakai M. Fish Shellfish Immunol. 15:263-268(2003) [PubMed: 12892747] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Kidney.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB084624 mRNA. Translation: BAB91437.1.
3D structure databases
HSSP	HSSP built from PDB template 153L based on UniProtKB P00718.
ModBase	Search...
Protein family/group databases
CAZy	GH23. Glycoside Hydrolase Family 23.
Phylogenomic databases
HOVERGEN	Q8JFR1.
Enzyme and pathway databases
BRENDA	3.2.1.17. 3298.
Family and domain databases
InterPro	IPR002152. Glyco_hydro_23. IPR008258. Lytic_TGlycosylase-like_cat. [Graphical view]
Pfam	PF01464. SLT. 1 hit. [Graphical view]
PIRSF	PIRSF001065. Lysozyme_g. 1 hit.
PRINTS	PR00749. LYSOZYMEG.
ProtoNet	Search...

Entry information

Entry name

LYG_CYPCA

Accession

Primary (citable) accession number: Q8JFR1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)