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Q8J1X7 (FUSC3_FUSCU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allergen Fus c 3
Alternative name(s):
Allergen=Fus c 3
OrganismFusarium culmorum
Taxonomic identifier5516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusarium

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Allergenic properties

Causes an allergic reaction in human. Binds to IgE. Ref.1

Sequence similarities

Contains 1 bHLH (basic helix-loop-helix) domain.

Ontologies

Keywords
   DiseaseAllergen
   LigandDNA-binding
Gene Ontology (GO)
   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 450450Allergen Fus c 3
PRO_0000127182

Regions

Domain368 – 44174bHLH

Sequences

Sequence LengthMass (Da)Tools
Q8J1X7 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 3BF89C3760851938

FASTA45048,938
        10         20         30         40         50         60 
MAGDHAGDQS FYDFLIEEPE MIAPTPPGQF PHQQPISSPN RTSRNTPLRP ESTEIETHHH 

        70         80         90        100        110        120 
ANHPPALPVL GMQLPVPGTV PESSRAQSRA SLNLDIDLDL HAPSHPSHLS HGAPHEQEHA 

       130        140        150        160        170        180 
HEIQRHRAHS AQSSAGLPPT GFASHLPPAS SGPVSLGWNM YHVPPNLHLN ANQFNFEVPG 

       190        200        210        220        230        240 
HMNVSGHPTH LEHSSTNPNS FHYEHNIVSP SSIHPSTAHF DGEVPSQWDD SLGHGASTPK 

       250        260        270        280        290        300 
VRTPSHHVSS NPWAEINEPT GGDNDNLAPV TRPRKPARAR RQKKEPRKLS DASQGARSSS 

       310        320        330        340        350        360 
TGGTAHSVSD AASPSSTSHQ SRASLTSKSA SMTSAASTAS SRKSKLRSAS RTSKNTLDKP 

       370        380        390        400        410        420 
NDTAEDRRTR ASHNLVEKQY RNRLNAQFES LLHALPEQIR HGDNGGGNGN VDNESEQAND 

       430        440        450 
LDRRVSKGEV LEMARRHIEA LERERNQLGT 

« Hide

References

[1]"Molecular cloning and immunological characterisation of potential allergens from the mould Fusarium culmorum."
Hoff M., Ballmer-Weber B.K., Niggemann B., Cistero-Bahima A., San Miguel-Moncin M., Conti A., Haustein D., Vieths S.
Mol. Immunol. 39:965-975(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY167564 mRNA. Translation: AAN73248.1.

3D structure databases

ProteinModelPortalQ8J1X7.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome1023. Fus c 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D4.10.280.10. 1 hit.
InterProIPR011598. bHLH_dom.
[Graphical view]
PfamPF00010. HLH. 1 hit.
[Graphical view]
SMARTSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMSSF47459. SSF47459. 1 hit.
PROSITEPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFUSC3_FUSCU
AccessionPrimary (citable) accession number: Q8J1X7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries