Q8J0K6 (Q8J0K6_MELAO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cellulose 1,4-beta-cellobiosidase EMBL CAD56667.1
EC=3.2.1.91 EMBL CAD56667.1

Gene names

Name:

cel7B EMBL CAD56667.1

Organism

Melanocarpus albomyces EMBL CAD56667.1

Taxonomic identifier

204285 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Sordariales › Sordariales incertae sedis › Melanocarpus

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Signal EMBL CAD56667.1
Molecular function	Glycosidase EMBL CAD56667.1 Hydrolase
Technical term	3D-structure PDB 2RFZ PDB 2RFY PDB 2RFW PDB 2RG0
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cellulose 1,4-beta-cellobiosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential EMBL CAD56667.1
	Chain	23 – 452	430	Potential EMBL CAD56667.1		PRO_5000069996

Sequences

	Sequence		Length	Mass (Da)
	Q8J0K6 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 3CC74C2D6908CCF3	FASTA	452	49,889
	10 20 30 40 50 60 MMMKQYLQYL AAALPLVGLA AGQRAGNETP ENHPPLTWQR CTAPGNCQTV NAEVVIDANW 70 80 90 100 110 120 RWLHDDNMQN CYDGNQWTNA CSTATDCAEK CMIEGAGDYL GTYGASTSGD ALTLKFVTKH 130 140 150 160 170 180 EYGTNVGSRF YLMNGPDKYQ MFNLMGNELA FDVDLSTVEC GINSALYFVA MEEDGGMASY 190 200 210 220 230 240 PSNQAGARYG TGYCDAQCAR DLKFVGGKAN IEGWKSSTSD PNAGVGPYGS CCAEIDVWES 250 260 270 280 290 300 NAYAFAFTPH ACTTNEYHVC ETTNCGGTYS EDRFAGKCDA NGCDYNPYRM GNPDFYGKGK 310 320 330 340 350 360 TLDTSRKFTV VSRFEENKLS QYFIQDGRKI EIPPPTWEGM PNSSEITPEL CSTMFDVFND 370 380 390 400 410 420 RNRFEEVGGF EQLNNALRVP MVLVMSIWDD HYANMLWLDS IYPPEKEGQP GAARGDCPTD 430 440 450 SGVPAEVEAQ FPDAQVVWSN IRFGPIGSTY DF

References

[1]	"Cloning of cellulase genes from Melanocarpus albomyces and their efficientexpression in Trichoderma reesei." Haakana H., Miettinen-Oinonen A., Joutsjoki V., Mantyla A., Suominen P., Vehmaanpera J. Enzyme Microb. Technol. 34:159-167(2004) Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding." Parkkinen T., Koivula A., Vehmaanpera J., Rouvinen J. Protein Sci. 17:1383-1394(2008) [PubMed: 18499583] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 24-452.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AJ515705 Genomic DNA. Translation: CAD56667.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2RFW	X-ray	1.60	A/B/C/D	24-452	[»]
2RFY	X-ray	1.70	A/B/C/D	24-452	[»]
2RFZ	X-ray	1.80	A/B/C/D	24-452	[»]
2RG0	X-ray	2.10	A/B/C/D	24-452	[»]

ProteinModelPortal

Q8J0K6.

SMR

Q8J0K6. Positions 23-451.

ModBase

Search...

Protein family/group databases

CAZy

GH7. Glycoside Hydrolase Family 7.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR008985. ConA-like_lec_gl.
IPR001722. Glyco_hydro_7.
[Graphical view]

Gene3D

G3DSA:2.70.100.10. Glyco_hydro_7. 1 hit.

Pfam

PF00840. Glyco_hydro_7. 1 hit.
[Graphical view]

PRINTS

PR00734. GLHYDRLASE7.

SUPFAM

SSF49899. ConA_like_lec_gl. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q8J0K6_MELAO

Accession

Primary (citable) accession number: Q8J0K6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 11, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)