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Q8J001

- Q8J001_HUMAN

UniProt

Q8J001 - Q8J001_HUMAN

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Protein
Submitted name:

Antithrombin

Gene

AT3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. heparin binding Source: Ensembl
  2. serine-type endopeptidase inhibitor activity Source: Ensembl

GO - Biological processi

  1. negative regulation of inflammatory response Source: Ensembl
  2. regulation of blood coagulation, intrinsic pathway Source: InterPro
  3. response to nutrient Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AntithrombinImported
Gene namesi
Name:AT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8J001.

Expressioni

Gene expression databases

BgeeiQ8J001.
ExpressionAtlasiQ8J001. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ8J001.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family.UniRule annotation

Family and domain databases

InterProiIPR015555. AT-III.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PTHR11461:SF53. PTHR11461:SF53. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8J001-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
VNEEGSAAAS TAVVIAGRSL NPNRVTFKAN RPFLVFIREV PLNTIIFMGR

VANPCVK
Length:57
Mass (Da):6,157
Last modified:March 1, 2003 - v1
Checksum:i5A6391B8ACA8BB4F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei57 – 571Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083701 Genomic DNA. Translation: BAC21173.1.
UniGeneiHs.75599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083701 Genomic DNA. Translation: BAC21173.1 .
UniGenei Hs.75599.

3D structure databases

ProteinModelPortali Q8J001.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8J001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q8J001.
ExpressionAtlasi Q8J001. baseline and differential.

Family and domain databases

InterProi IPR015555. AT-III.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view ]
PANTHERi PTHR11461. PTHR11461. 1 hit.
PTHR11461:SF53. PTHR11461:SF53. 1 hit.
Pfami PF00079. Serpin. 1 hit.
[Graphical view ]
SUPFAMi SSF56574. SSF56574. 1 hit.
PROSITEi PS00284. SERPIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Gene Analysis of Anticoagulation Factors in Japanese Thrombotic Patients. Genetic Background of Thrombophilia in Japan."
    Kinoshita S., Iida H., Inoue S., Watanabe K., Kurihara M., Wada Y., Ono M., Dongchon K., Hamasaki N.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8J001_HUMAN
AccessioniPrimary (citable) accession number: Q8J001
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.