Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8J001

- Q8J001_HUMAN

UniProt

Q8J001 - Q8J001_HUMAN

Protein
Submitted name:

Antithrombin

Gene

AT3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. heparin binding Source: Ensembl
    2. serine-type endopeptidase inhibitor activity Source: Ensembl

    GO - Biological processi

    1. negative regulation of inflammatory response Source: Ensembl
    2. regulation of blood coagulation, intrinsic pathway Source: InterPro
    3. response to nutrient Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AntithrombinImported
    Gene namesi
    Name:AT3Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8J001.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8J001.
    BgeeiQ8J001.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8J001.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.UniRule annotation

    Family and domain databases

    InterProiIPR015555. AT-III.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF53. PTHR11461:SF53. 1 hit.
    PfamiPF00079. Serpin. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 1 hit.
    PROSITEiPS00284. SERPIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8J001-1 [UniParc]FASTAAdd to Basket

    « Hide

    VNEEGSAAAS TAVVIAGRSL NPNRVTFKAN RPFLVFIREV PLNTIIFMGR   50
    VANPCVK 57
    Length:57
    Mass (Da):6,157
    Last modified:March 1, 2003 - v1
    Checksum:i5A6391B8ACA8BB4F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei57 – 571Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083701 Genomic DNA. Translation: BAC21173.1.
    UniGeneiHs.75599.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083701 Genomic DNA. Translation: BAC21173.1 .
    UniGenei Hs.75599.

    3D structure databases

    ProteinModelPortali Q8J001.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8J001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q8J001.
    Bgeei Q8J001.

    Family and domain databases

    InterProi IPR015555. AT-III.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF53. PTHR11461:SF53. 1 hit.
    Pfami PF00079. Serpin. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 1 hit.
    PROSITEi PS00284. SERPIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Gene Analysis of Anticoagulation Factors in Japanese Thrombotic Patients. Genetic Background of Thrombophilia in Japan."
      Kinoshita S., Iida H., Inoue S., Watanabe K., Kurihara M., Wada Y., Ono M., Dongchon K., Hamasaki N.
      Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8J001_HUMAN
    AccessioniPrimary (citable) accession number: Q8J001
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.