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Protein

Protein FAM9A

Gene

FAM9A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM9A
Gene namesi
Name:FAM9A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:18403. FAM9A.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27992.

Polymorphism and mutation databases

BioMutaiFAM9A.
DMDMi29336759.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332Protein FAM9APRO_0000119032Add
BLAST

Proteomic databases

PaxDbiQ8IZU1.
PRIDEiQ8IZU1.

Expressioni

Tissue specificityi

Expressed exclusively in testis.1 Publication

Gene expression databases

BgeeiQ8IZU1.
CleanExiHS_FAM9A.
GenevisibleiQ8IZU1. HS.

Organism-specific databases

HPAiHPA056076.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KDM1AO603412EBI-8468186,EBI-710124
PRMT1Q998732EBI-8468186,EBI-78738

Protein-protein interaction databases

BioGridi128130. 20 interactions.
IntActiQ8IZU1. 5 interactions.
MINTiMINT-8417663.
STRINGi9606.ENSP00000370391.

Structurei

3D structure databases

ProteinModelPortaliQ8IZU1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi180 – 27596Glu-richAdd
BLAST
Compositional biasi194 – 21421Poly-AlaAdd
BLAST
Compositional biasi252 – 2587Poly-Gly

Sequence similaritiesi

Belongs to the FAM9 family.Curated

Phylogenomic databases

eggNOGiENOG410ISM0. Eukaryota.
ENOG4110Q03. LUCA.
GeneTreeiENSGT00390000003272.
HOGENOMiHOG000206619.
InParanoidiQ8IZU1.
OMAiYIAADIK.
OrthoDBiEOG7DVDCD.
PhylomeDBiQ8IZU1.

Sequencei

Sequence statusi: Complete.

Q8IZU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPVGRKRSR KAAKAQLEAQ VTAAQGATKE GSGIASNFPG QPTMEPVGRK
60 70 80 90 100
RSRKAAKAQL EAQVRAAPAK KHTGKDPVRD ECEERNPFTE TREEDVTDEH
110 120 130 140 150
GEREPFAEKD EHTGIHTMKL EHIAADIKKG LAAKREMIKI DKAAYRKTKN
160 170 180 190 200
TIERALKKKQ LKRQKRDYRH TRKLLNVLKE YIAEKQKDDE AEEAEAAAAA
210 220 230 240 250
AEAAAAAEAA AAAAEVIVVE DEEEEEKEEE EEKEEEEEEG EEEGGGEEGE
260 270 280 290 300
EGGGGGEGEE TEEEEEEEEE EEEEEQIKAF QEKQKRWQQP TGVRSWRLRE
310 320 330
MKPLLEQLLK AAKDTKDNYC IISSSEESEL DN
Length:332
Mass (Da):37,339
Last modified:March 1, 2003 - v1
Checksum:i92F22EC36038229C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF494343 mRNA. Translation: AAN07162.1.
BC112022 mRNA. Translation: AAI12023.1.
BC113449 mRNA. Translation: AAI13450.1.
BC143805 mRNA. Translation: AAI43806.1.
CCDSiCCDS14131.1.
RefSeqiNP_001164657.1. NM_001171186.1.
NP_777611.1. NM_174951.3.
XP_011543765.1. XM_011545463.1.
UniGeneiHs.382062.

Genome annotation databases

EnsembliENST00000381003; ENSP00000370391; ENSG00000183304.
ENST00000543214; ENSP00000440163; ENSG00000183304.
GeneIDi171482.
KEGGihsa:171482.
UCSCiuc004csg.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF494343 mRNA. Translation: AAN07162.1.
BC112022 mRNA. Translation: AAI12023.1.
BC113449 mRNA. Translation: AAI13450.1.
BC143805 mRNA. Translation: AAI43806.1.
CCDSiCCDS14131.1.
RefSeqiNP_001164657.1. NM_001171186.1.
NP_777611.1. NM_174951.3.
XP_011543765.1. XM_011545463.1.
UniGeneiHs.382062.

3D structure databases

ProteinModelPortaliQ8IZU1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128130. 20 interactions.
IntActiQ8IZU1. 5 interactions.
MINTiMINT-8417663.
STRINGi9606.ENSP00000370391.

Polymorphism and mutation databases

BioMutaiFAM9A.
DMDMi29336759.

Proteomic databases

PaxDbiQ8IZU1.
PRIDEiQ8IZU1.

Protocols and materials databases

DNASUi171482.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381003; ENSP00000370391; ENSG00000183304.
ENST00000543214; ENSP00000440163; ENSG00000183304.
GeneIDi171482.
KEGGihsa:171482.
UCSCiuc004csg.4. human.

Organism-specific databases

CTDi171482.
GeneCardsiFAM9A.
HGNCiHGNC:18403. FAM9A.
HPAiHPA056076.
MIMi300477. gene.
neXtProtiNX_Q8IZU1.
PharmGKBiPA27992.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ISM0. Eukaryota.
ENOG4110Q03. LUCA.
GeneTreeiENSGT00390000003272.
HOGENOMiHOG000206619.
InParanoidiQ8IZU1.
OMAiYIAADIK.
OrthoDBiEOG7DVDCD.
PhylomeDBiQ8IZU1.

Miscellaneous databases

GenomeRNAii171482.
NextBioi89254.
PROiQ8IZU1.
SOURCEiSearch...

Gene expression databases

BgeeiQ8IZU1.
CleanExiHS_FAM9A.
GenevisibleiQ8IZU1. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region."
    Martinez-Garay I., Jablonka S., Sutajova M., Steuernagel P., Gal A., Kutsche K.
    Genomics 80:259-267(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiFAM9A_HUMAN
AccessioniPrimary (citable) accession number: Q8IZU1
Secondary accession number(s): B7ZLH5, Q2M2D1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2003
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.