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Protein

Protein FAM9C

Gene

FAM9C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM9C
Gene namesi
Name:FAM9C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:18405. FAM9C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27994.

Polymorphism and mutation databases

BioMutaiFAM9C.
DMDMi29336757.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 166166Protein FAM9CPRO_0000119034Add
BLAST

Proteomic databases

PaxDbiQ8IZT9.
PeptideAtlasiQ8IZT9.
PRIDEiQ8IZT9.
TopDownProteomicsiQ8IZT9.

Expressioni

Tissue specificityi

Expressed exclusively in testis.1 Publication

Gene expression databases

BgeeiQ8IZT9.
CleanExiHS_FAM9C.
ExpressionAtlasiQ8IZT9. baseline and differential.
GenevisibleiQ8IZT9. HS.

Organism-specific databases

HPAiHPA060697.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TPM3P067533EBI-2870039,EBI-355607
TPM3Q5VU623EBI-2870039,EBI-10184033

Protein-protein interaction databases

BioGridi128132. 1 interaction.
IntActiQ8IZT9. 3 interactions.
STRINGi9606.ENSP00000334430.

Structurei

3D structure databases

ProteinModelPortaliQ8IZT9.
SMRiQ8IZT9. Positions 71-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM9 family.Curated

Phylogenomic databases

eggNOGiENOG410IUQ6. Eukaryota.
ENOG4110NS3. LUCA.
GeneTreeiENSGT00390000003272.
HOGENOMiHOG000112495.
InParanoidiQ8IZT9.
OMAiQQDGKGT.
OrthoDBiEOG7QZGCH.
PhylomeDBiQ8IZT9.
TreeFamiTF328876.

Family and domain databases

InterProiIPR006888. XLR/SYCP3/FAM9_dom.
[Graphical view]
PfamiPF04803. Cor1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IZT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDQLEVQ VMAAQEMELA GKDPVSHEHE ERKPVTETKE GDVTDEHGER
60 70 80 90 100
GSFAETDEHT GVDTKELEDI AADIKEHLAA KRKRIEKIAK ACSEIKNRIK
110 120 130 140 150
NVLRTTQLKR QKRDYRISLK LPNVLEEFIT DEQKDEEGDG EKEEQIKIFQ
160
EQQKRWQQDG KGTERD
Length:166
Mass (Da):19,210
Last modified:March 1, 2003 - v1
Checksum:i247460DA7E86FB66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF494345 mRNA. Translation: AAN07164.1.
AK313776 mRNA. Translation: BAG36514.1.
BX647580 mRNA. Translation: CAI46094.1.
BC127957 mRNA. Translation: AAI27958.1.
CCDSiCCDS35203.1.
RefSeqiNP_777561.1. NM_174901.5.
XP_005274517.1. XM_005274460.2.
UniGeneiHs.667546.

Genome annotation databases

EnsembliENST00000333995; ENSP00000334430; ENSG00000187268.
ENST00000380625; ENSP00000369999; ENSG00000187268.
GeneIDi171484.
KEGGihsa:171484.
UCSCiuc004cvg.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF494345 mRNA. Translation: AAN07164.1.
AK313776 mRNA. Translation: BAG36514.1.
BX647580 mRNA. Translation: CAI46094.1.
BC127957 mRNA. Translation: AAI27958.1.
CCDSiCCDS35203.1.
RefSeqiNP_777561.1. NM_174901.5.
XP_005274517.1. XM_005274460.2.
UniGeneiHs.667546.

3D structure databases

ProteinModelPortaliQ8IZT9.
SMRiQ8IZT9. Positions 71-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128132. 1 interaction.
IntActiQ8IZT9. 3 interactions.
STRINGi9606.ENSP00000334430.

Polymorphism and mutation databases

BioMutaiFAM9C.
DMDMi29336757.

Proteomic databases

PaxDbiQ8IZT9.
PeptideAtlasiQ8IZT9.
PRIDEiQ8IZT9.
TopDownProteomicsiQ8IZT9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000333995; ENSP00000334430; ENSG00000187268.
ENST00000380625; ENSP00000369999; ENSG00000187268.
GeneIDi171484.
KEGGihsa:171484.
UCSCiuc004cvg.4. human.

Organism-specific databases

CTDi171484.
GeneCardsiFAM9C.
HGNCiHGNC:18405. FAM9C.
HPAiHPA060697.
MIMi300479. gene.
neXtProtiNX_Q8IZT9.
PharmGKBiPA27994.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IUQ6. Eukaryota.
ENOG4110NS3. LUCA.
GeneTreeiENSGT00390000003272.
HOGENOMiHOG000112495.
InParanoidiQ8IZT9.
OMAiQQDGKGT.
OrthoDBiEOG7QZGCH.
PhylomeDBiQ8IZT9.
TreeFamiTF328876.

Miscellaneous databases

GenomeRNAii171484.
PROiQ8IZT9.
SOURCEiSearch...

Gene expression databases

BgeeiQ8IZT9.
CleanExiHS_FAM9C.
ExpressionAtlasiQ8IZT9. baseline and differential.
GenevisibleiQ8IZT9. HS.

Family and domain databases

InterProiIPR006888. XLR/SYCP3/FAM9_dom.
[Graphical view]
PfamiPF04803. Cor1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region."
    Martinez-Garay I., Jablonka S., Sutajova M., Steuernagel P., Gal A., Kutsche K.
    Genomics 80:259-267(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiFAM9C_HUMAN
AccessioniPrimary (citable) accession number: Q8IZT9
Secondary accession number(s): B2R9G7, Q5HYJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.