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Q8IZJ3

- CPMD8_HUMAN

UniProt

Q8IZJ3 - CPMD8_HUMAN

Protein

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8

Gene

CPAMD8

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 2 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei671 – 6722Cleavage; by furin-like proteaseCurated

    GO - Molecular functioni

    1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Protease inhibitor, Serine protease inhibitor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8
    Gene namesi
    Name:CPAMD8
    Synonyms:KIAA1283
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:23228. CPAMD8.

    Subcellular locationi

    Secreted 1 Publication. Cell membrane 1 Publication; Peripheral membrane protein 1 Publication; Extracellular side 1 Publication

    GO - Cellular componenti

    1. extracellular space Source: InterPro
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane, Secreted

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134915057.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 18851860C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8PRO_0000317695Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi117 – 1171N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi190 – 1901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi267 – 2671N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi757 – 7571N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1439 – 14391N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Proteolytically cleaved into 2 chains of about 70 and 130 kDa. The fragments are not connected by disulfide bonds.1 Publication

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8IZJ3.
    PRIDEiQ8IZJ3.

    PTM databases

    PhosphoSiteiQ8IZJ3.

    Expressioni

    Tissue specificityi

    Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine.1 Publication

    Inductioni

    Up-regulated by IL1B/interleukin-1 beta and IL6/interleukin-6.1 Publication

    Gene expression databases

    ArrayExpressiQ8IZJ3.
    BgeeiQ8IZJ3.
    CleanExiHS_CPAMD8.
    GenevestigatoriQ8IZJ3.

    Organism-specific databases

    HPAiHPA031330.

    Interactioni

    Subunit structurei

    Interacts with heparin.1 Publication

    Protein-protein interaction databases

    BioGridi118033. 3 interactions.
    STRINGi9606.ENSP00000291440.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IZJ3.
    SMRiQ8IZJ3. Positions 30-948, 1107-1681, 1711-1760.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1706 – 175752Kazal-likePROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi668 – 6714Poly-Arg
    Compositional biasi1242 – 12454Poly-Gln
    Compositional biasi1540 – 15434Poly-Asp
    Compositional biasi1765 – 17684Poly-Ser

    Sequence similaritiesi

    Contains 1 Kazal-like domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG241555.
    HOGENOMiHOG000168521.
    HOVERGENiHBG107753.
    InParanoidiQ8IZJ3.
    OrthoDBiEOG747PH3.
    PhylomeDBiQ8IZJ3.
    TreeFamiTF313285.

    Family and domain databases

    Gene3Di1.50.10.20. 1 hit.
    2.60.40.690. 1 hit.
    InterProiIPR009048. A-macroglobulin_rcpt-bd.
    IPR011626. A2M_comp.
    IPR002890. A2M_N.
    IPR011625. A2M_N_2.
    IPR014756. Ig_E-set.
    IPR002350. Kazal_dom.
    IPR001599. Macroglobln_a2.
    IPR019742. MacrogloblnA2_CS.
    IPR019565. MacrogloblnA2_thiol-ester-bond.
    IPR022041. Methyltransf_FA.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view]
    PfamiPF00207. A2M. 1 hit.
    PF07678. A2M_comp. 1 hit.
    PF01835. A2M_N. 1 hit.
    PF07703. A2M_N_2. 1 hit.
    PF07677. A2M_recep. 1 hit.
    PF07648. Kazal_2. 1 hit.
    PF12248. Methyltransf_FA. 1 hit.
    PF10569. Thiol-ester_cl. 1 hit.
    [Graphical view]
    SMARTiSM00280. KAZAL. 1 hit.
    [Graphical view]
    SUPFAMiSSF48239. SSF48239. 1 hit.
    SSF49410. SSF49410. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00477. ALPHA_2_MACROGLOBULIN. 1 hit.
    PS51465. KAZAL_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8IZJ3-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSGALLWPLL PLLLLLLSAR DGVRAAQPQA PGYLIAAPSV FRAGVEEVIS     50
    VTIFNSPREV TVQAQLVAQG EPVVQSQGAI LDKGTIKLKV PTGLRGQALL 100
    KVWGRGWQAE EGPLFHNQTS VTVDGRGASV FIQTDKPVYR PQHRVLISIF 150
    TVSPNLRPVN EKLEAYILDP RGSRMIEWRH LKPFCCGITN MSFPLSDQPV 200
    LGEWFIFVEM QGHAYNKSFE VQKYVLPKFE LLIDPPRYIQ DLDACETGTV 250
    RARYTFGKPV AGALMINMTV NGVGYYSHEV GRPVLRTTKI LGSRDFDICV 300
    RDMIPADVPE HFRGRVSIWA MVTSVDGSQQ VAFDDSTPVQ RQLVDIRYSK 350
    DTRKQFKPGL AYVGKVELSY PDGSPAEGVT VQIKAELTPK DNIYTSEVVS 400
    QRGLVGFEIP SIPTSAQHVW LETKVMALNG KPVGAQYLPS YLSLGSWYSP 450
    SQCYLQLQPP SHPLQVGEEA YFSVKSTCPC NFTLYYEVAA RGNIVLSGQQ 500
    PAHTTQQRSK RAAPALEKPI RLTHLSETEP PPAPEAEVDV CVTSLHLAVT 550
    PSMVPLGRLL VFYVRENGEG VADSLQFAVE TFFENQVSVT YSANETQPGE 600
    VVDLRIRAAR GSCVCVAAVD KSVYLLRSGF RLTPAQVFQE LEDYDVSDSF 650
    GVSREDGPFW WAGLTAQRRR RSSVFPWPWG ITKDSGFAFT ETGLVVMTDR 700
    VSLNHRQDGG LYTDEAVPAF QPHTGSLVAV APSRHPPRTE KRKRTFFPET 750
    WIWHCLNISD PSGEGTLSVK VPDSITSWVG EAVALSTSQG LGIAEPSLLK 800
    TFKPFFVDFM LPALIIRGEQ VKIPLSVYNY MGTCAEVYMK LSVPKGIQFV 850
    GHPGKRHVTK KMCVAPGEAE PIWVVLSFSD LGLNNITAKA LAYGDTNCCR 900
    DGRSSKHPEE NHADRRVPIG VDHVRRSVMV EAEGVPRAYT YSAFFCPSER 950
    VHISTPNKYE FQYVQRPLRL TRFDVAVRAH NDARVALSSG PQDTAGMIEI 1000
    VLGGHQNTRS WISTSKMGEP VASAHTAKIL SWDEFRTFWI SWRGGLIQVG 1050
    HGPEPSNESV IVAWTLPRPP EVQFIGFSTG WGSMGEFRIW RKMEVDESYS 1100
    EAFTLGVPHG AIPGSERATA SIIGDVMGPT LNHLNNLLRL PFGCGEQNMI 1150
    HFAPNVFVLK YLQKTQQLSP EVERETTDYL VQGYQRQLTY KRQDGSYSAF 1200
    GERDASGSMW LTAFVLKSFA QARSFIFVDP RELAAAKSWI IQQQQADGSF 1250
    LAVGRVLNKD IQGGIHGTVP LTAYVVVALL ETGTASEEER GSTDKARHFL 1300
    ESAAPLAMDP YSCALTTYAL TLLRSPAAPE ALRKLRSLAI MRDGVTHWSL 1350
    SNSWDVDKGT FLSFSDRVSQ SVVSAEVEMT AYALLTYTLL GDVAAALPVV 1400
    KWLSQQRNAL GGFSSTQDTC VALQALAEYA ILSYAGGINL TVSLASTNLD 1450
    YQETFELHRT NQKVLQTAAI PSLPTGLFVS AKGDGCCLMQ IDVTYNVPDP 1500
    VAKPAFQLLV SLQEPEAQGR PPPMPASAAE GSRGDWPPAD DDDPAADQHH 1550
    QEYKVMLEVC TRWLHAGSSN MAVLEVPLLS GFRADIESLE QLLLDKHMGM 1600
    KRYEVAGRRV LFYFDEIPSR CLTCVRFRAL RECVVGRTSA LPVSVYDYYE 1650
    PAFEATRFYN VSTHSPLARE LCAGPACNEV ERAPARGPGW FPGESGPAVA 1700
    PEEGAAIARC GCDHDCGAQG NPVCGSDGVV YASACRLREA ACRQAAPLEP 1750
    APPSCCALEQ RLPASSSSTY GDDLASVAPG PLQQDVKLNG AGLEVEDSDP 1800
    EPEGEAEDRV TAGPRPPVSS GNLESSTQSA SPFHRWGQTP APQRHSGRVV 1850
    GAHRPGLLSP VFVYSPAFQS GGEEGLWMSN TCTLR 1885
    Length:1,885
    Mass (Da):206,702
    Last modified:September 22, 2009 - v2
    Checksum:i5AA522DE6155C288
    GO
    Isoform 2 (identifier: Q8IZJ3-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1809-1815: RVTAGPR → SQSGFSS
         1816-1885: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,815
    Mass (Da):199,171
    Checksum:iE8F8D6DA1DECDB6D
    GO

    Sequence cautioni

    The sequence BAC11400.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti1588 – 15881S → G in BAC11400. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti251 – 2511R → W.
    Corresponds to variant rs10426545 [ dbSNP | Ensembl ].
    VAR_038655
    Natural varianti265 – 2651M → T.
    Corresponds to variant rs4808551 [ dbSNP | Ensembl ].
    VAR_038656
    Natural varianti294 – 2941R → Q.2 Publications
    Corresponds to variant rs3745340 [ dbSNP | Ensembl ].
    VAR_038657
    Natural varianti539 – 5391D → E.
    Corresponds to variant rs3745335 [ dbSNP | Ensembl ].
    VAR_038658
    Natural varianti546 – 5461H → R.
    Corresponds to variant rs1824152 [ dbSNP | Ensembl ].
    VAR_038659
    Natural varianti736 – 7361P → H.
    Corresponds to variant rs9305083 [ dbSNP | Ensembl ].
    VAR_038660
    Natural varianti1156 – 11561V → I.
    Corresponds to variant rs2250918 [ dbSNP | Ensembl ].
    VAR_038661
    Natural varianti1268 – 12681T → I.2 Publications
    Corresponds to variant rs706761 [ dbSNP | Ensembl ].
    VAR_038662
    Natural varianti1843 – 18431Q → R.
    Corresponds to variant rs1054533 [ dbSNP | Ensembl ].
    VAR_038663

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1809 – 18157RVTAGPR → SQSGFSS in isoform 2. 1 PublicationVSP_031137
    Alternative sequencei1816 – 188570Missing in isoform 2. 1 PublicationVSP_031138Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY101765 mRNA. Translation: AAM50084.1.
    AC008737 Genomic DNA. No translation available.
    AC020908 Genomic DNA. No translation available.
    AB033109 mRNA. Translation: BAA86597.1.
    AK075099 mRNA. Translation: BAC11400.1. Different initiation.
    RefSeqiNP_056507.2. NM_015692.2.
    UniGeneiHs.631644.

    Genome annotation databases

    EnsembliENST00000291440; ENSP00000291440; ENSG00000160111.
    ENST00000443236; ENSP00000402505; ENSG00000160111.
    GeneIDi27151.
    KEGGihsa:27151.
    UCSCiuc002nfb.3. human. [Q8IZJ3-1]

    Polymorphism databases

    DMDMi259016204.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY101765 mRNA. Translation: AAM50084.1 .
    AC008737 Genomic DNA. No translation available.
    AC020908 Genomic DNA. No translation available.
    AB033109 mRNA. Translation: BAA86597.1 .
    AK075099 mRNA. Translation: BAC11400.1 . Different initiation.
    RefSeqi NP_056507.2. NM_015692.2.
    UniGenei Hs.631644.

    3D structure databases

    ProteinModelPortali Q8IZJ3.
    SMRi Q8IZJ3. Positions 30-948, 1107-1681, 1711-1760.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 118033. 3 interactions.
    STRINGi 9606.ENSP00000291440.

    PTM databases

    PhosphoSitei Q8IZJ3.

    Polymorphism databases

    DMDMi 259016204.

    Proteomic databases

    PaxDbi Q8IZJ3.
    PRIDEi Q8IZJ3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000291440 ; ENSP00000291440 ; ENSG00000160111 .
    ENST00000443236 ; ENSP00000402505 ; ENSG00000160111 .
    GeneIDi 27151.
    KEGGi hsa:27151.
    UCSCi uc002nfb.3. human. [Q8IZJ3-1 ]

    Organism-specific databases

    CTDi 27151.
    GeneCardsi GC19M017003.
    H-InvDB HIX0014878.
    HGNCi HGNC:23228. CPAMD8.
    HPAi HPA031330.
    MIMi 608841. gene.
    neXtProti NX_Q8IZJ3.
    PharmGKBi PA134915057.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG241555.
    HOGENOMi HOG000168521.
    HOVERGENi HBG107753.
    InParanoidi Q8IZJ3.
    OrthoDBi EOG747PH3.
    PhylomeDBi Q8IZJ3.
    TreeFami TF313285.

    Miscellaneous databases

    GenomeRNAii 27151.
    NextBioi 49911.
    PROi Q8IZJ3.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8IZJ3.
    Bgeei Q8IZJ3.
    CleanExi HS_CPAMD8.
    Genevestigatori Q8IZJ3.

    Family and domain databases

    Gene3Di 1.50.10.20. 1 hit.
    2.60.40.690. 1 hit.
    InterProi IPR009048. A-macroglobulin_rcpt-bd.
    IPR011626. A2M_comp.
    IPR002890. A2M_N.
    IPR011625. A2M_N_2.
    IPR014756. Ig_E-set.
    IPR002350. Kazal_dom.
    IPR001599. Macroglobln_a2.
    IPR019742. MacrogloblnA2_CS.
    IPR019565. MacrogloblnA2_thiol-ester-bond.
    IPR022041. Methyltransf_FA.
    IPR008930. Terpenoid_cyclase/PrenylTrfase.
    [Graphical view ]
    Pfami PF00207. A2M. 1 hit.
    PF07678. A2M_comp. 1 hit.
    PF01835. A2M_N. 1 hit.
    PF07703. A2M_N_2. 1 hit.
    PF07677. A2M_recep. 1 hit.
    PF07648. Kazal_2. 1 hit.
    PF12248. Methyltransf_FA. 1 hit.
    PF10569. Thiol-ester_cl. 1 hit.
    [Graphical view ]
    SMARTi SM00280. KAZAL. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48239. SSF48239. 1 hit.
    SSF49410. SSF49410. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00477. ALPHA_2_MACROGLOBULIN. 1 hit.
    PS51465. KAZAL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of CPAMD8, a novel member of the complement 3/alpha2-macroglobulin family with a C-terminal Kazal domain."
      Li Z.-F., Wu X.-H., Engvall E.
      Genomics 83:1083-1093(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), IDENTIFICATION BY MASS SPECTROMETRY, TISSUE SPECIFICITY, CLEAVAGE BY FURIN-LIKE PROTEASE, SUBCELLULAR LOCATION, INDUCTION BY IL1B AND IL6, INTERACTION WITH HEPARIN, VARIANTS GLN-294 AND ILE-1268.
    2. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O.
      DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-1885 (ISOFORM 1), VARIANTS GLN-294 AND ILE-1268.
      Tissue: Brain.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1479-1885 (ISOFORM 2).
      Tissue: Placenta.

    Entry informationi

    Entry nameiCPMD8_HUMAN
    AccessioniPrimary (citable) accession number: Q8IZJ3
    Secondary accession number(s): Q8NC09, Q9ULD7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 90 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3