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Unreviewed, UniProtKB/TrEMBL Q8IZI3 (Q8IZI3_HUMAN)

Last modified January 19, 2010. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    LEF1 EMBL AAN06089.1
OrganismHomo sapiens (Human) EMBL AAN06089.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processWnt receptor signaling pathway

Inferred from electronic annotation. Source: Compara

cell adhesion

Inferred from electronic annotation. Source: Compara

dentate gyrus development

Inferred from electronic annotation. Source: Compara

embryonic limb morphogenesis

Inferred from electronic annotation. Source: Compara

epithelial to mesenchymal transition

Inferred from electronic annotation. Source: Compara

kidney development

Inferred from electronic annotation. Source: Compara

mammary gland development

Inferred from electronic annotation. Source: Compara

negative regulation of striated muscle tissue development

Inferred from electronic annotation. Source: Compara

negative regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

odontogenesis of dentine-containing tooth

Inferred from electronic annotation. Source: Compara

palate development

Inferred from electronic annotation. Source: Compara

paraxial mesoderm formation

Inferred from electronic annotation. Source: Compara

placenta development

Inferred from electronic annotation. Source: Compara

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

regulation of Wnt receptor signaling pathway

Inferred from electronic annotation. Source: Compara

response to lithium ion

Inferred from electronic annotation. Source: Compara

response to organic cyclic substance

Inferred from electronic annotation. Source: Compara

skin development

Inferred from electronic annotation. Source: Compara

somitogenesis

Inferred from electronic annotation. Source: Compara

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: Compara

transcription factor complex

Inferred from electronic annotation. Source: Compara

   Molecular functionDNA bending activity

Inferred from electronic annotation. Source: Compara

RNA polymerase II transcription factor activity, enhancer binding

Inferred from electronic annotation. Source: Compara

chromatin binding

Inferred from electronic annotation. Source: Compara

protein binding

Inferred from electronic annotation. Source: Compara

transcription activator activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue201 EMBL AAN06089.1

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Sequences

Sequence LengthMass (Da)Tools
Q8IZI3-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: E4F1891E56FBA675

FASTA201,761
        10         20 
MPQLSGGGGG GGGDPELCAT

« Hide

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References

[1]"Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter."
Filali M., Cheng N., Abbott D., Leontiev V., Engelhardt J.F.
J. Biol. Chem. 277:33398-33410(2002) [PubMed: 12052822] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY129650 Genomic DNA. Translation: AAN06089.1.
IPIIPI00220455.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ8IZI3.

Genome annotation databases

EnsemblENST00000265165; ENSP00000265165; ENSG00000138795; Homo sapiens. [Genome view]
ENST00000379951; ENSP00000369284; ENSG00000138795; Homo sapiens. [Genome view]
ENST00000415535; ENSP00000415966; ENSG00000138795; Homo sapiens. [Genome view]
ENST00000438313; ENSP00000406176; ENSG00000138795; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:6551. LEF1.

Phylogenomic databases

HOVERGENQ8IZI3.

Gene expression databases

ArrayExpressQ8IZI3.
BgeeQ8IZI3.

Family and domain databases

ProtoNetSearch...

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Entry information

Entry nameQ8IZI3_HUMAN
AccessionPrimary (citable) accession number: Q8IZI3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: January 19, 2010
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information