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Q8IZF6

- GP112_HUMAN

UniProt

Q8IZF6 - GP112_HUMAN

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Protein

Probable G-protein coupled receptor 112

Gene
GPR112
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: GDB

GO - Biological processi

  1. G-protein coupled receptor signaling pathway Source: GDB
  2. neuropeptide signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Protein family/group databases

MEROPSiS63.017.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 112
Gene namesi
Name:GPR112
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:18992. GPR112.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini28 – 27412714Extracellular Reviewed predictionAdd
BLAST
Transmembranei2742 – 276221Helical; Name=1; Reviewed predictionAdd
BLAST
Topological domaini2763 – 277816Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei2779 – 279921Helical; Name=2; Reviewed predictionAdd
BLAST
Topological domaini2800 – 28056Extracellular Reviewed prediction
Transmembranei2806 – 282621Helical; Name=3; Reviewed predictionAdd
BLAST
Topological domaini2827 – 284822Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei2849 – 286921Helical; Name=4; Reviewed predictionAdd
BLAST
Topological domaini2870 – 289223Extracellular Reviewed predictionAdd
BLAST
Transmembranei2893 – 291321Helical; Name=5; Reviewed predictionAdd
BLAST
Topological domaini2914 – 294229Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei2943 – 296321Helical; Name=6; Reviewed predictionAdd
BLAST
Topological domaini2964 – 29652Extracellular Reviewed prediction
Transmembranei2966 – 298621Helical; Name=7; Reviewed predictionAdd
BLAST
Topological domaini2987 – 308094Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: GDB
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134885132.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727 Reviewed predictionAdd
BLAST
Chaini28 – 30803053Probable G-protein coupled receptor 112PRO_0000070335Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi233 – 2331N-linked (GlcNAc...) Reviewed prediction
Glycosylationi487 – 4871N-linked (GlcNAc...) Reviewed prediction
Glycosylationi836 – 8361N-linked (GlcNAc...) Reviewed prediction
Glycosylationi899 – 8991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1020 – 10201N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1519 – 15191N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2361 – 23611N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2640 – 26401N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ8IZF6.
PaxDbiQ8IZF6.
PRIDEiQ8IZF6.

PTM databases

PhosphoSiteiQ8IZF6.

Expressioni

Tissue specificityi

Detected in fetal retina. Highly expressed in normal enterochromaffin cells and in neuroendocrine carcinoma. Detected in normal liver; highly expressed in primary liver carcinoma.1 Publication

Gene expression databases

BgeeiQ8IZF6.
CleanExiHS_GPR112.
GenevestigatoriQ8IZF6.

Organism-specific databases

HPAiHPA035324.

Structurei

3D structure databases

ProteinModelPortaliQ8IZF6.
SMRiQ8IZF6. Positions 2645-2721, 2741-2989.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2682 – 273352GPSAdd
BLAST

Sequence similaritiesi

Contains 1 GPS domain.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000230882.
KOiK08455.
OMAiYFQLWDH.
OrthoDBiEOG7ZGX28.
PhylomeDBiQ8IZF6.
TreeFamiTF321769.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR001759. Pentaxin.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
PF00354. Pentaxin. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8IZF6-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP     50
ELSRFTACID LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI 100
LYRLGKTFSI RHHLASFQWH TICLIWDGVK GKLELFLNKE RILEVTDQPH 150
NLTPHGTLFL GHFLKNESSE VKSMMRSFPG SLYYFQLWDH ILENEEFMKC 200
LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS TTVSQQIDMT 250
TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ 300
KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES 350
TKTTKMVEAM ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT 400
TSLFSTIEST SMSTTPCLKQ KSTNTGALPI STAGQEFIES TAAGTVPWFT 450
VEKTSPASTH VGTASSFPPE PVLISTAAPV DSVFPRNQTA FPLATTDMKI 500
AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV EDAMSTSMSK 550
ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS 600
STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS 650
SNETIWTSRP DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT 700
NITPLKASPE GKGTTANDAT TARYTTAVSK LTSPWFANFS IVSGTTSITN 750
MPEFKLTTLL LKTIPMSTKP ANELPLTPRE TVVPSVDIIS TLACIQPNFS 800
TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT RKEATSHYLM 850
RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK 900
TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS 950
AGSPTSGSTH IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT 1000
AAHSSATPVP VTHMFSLPVN GSSVVAEETE VTMSEPSTLA RAFSTSVLSD 1050
VSNLSSTTMT TALVPPLDQT ASTTIVIVPT HGDLIRTTSE ATVISVRKTS 1100
MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST HTLVCSKPPP 1150
DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL 1200
ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS 1250
TSVLSSDKDQ MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG 1300
FPETTKISSH QTHSPSEIPL GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG 1350
VHIPEMSTSL GKTALPSQAL TITTFLCPEK ESTSALPAYT PRTVEMIVNS 1400
TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH SLRTQPEVTS 1450
VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR 1500
ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS 1550
PCTATSGPMS EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT 1600
MTMQTSTLDV TPVIYAGATS KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE 1650
PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL SSKSTGAISS IPKTTFSPFL 1700
SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT YSRITVPENM 1750
LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS 1800
LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP 1850
KTSPPPTSQM VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN 1900
VPTSNEMETE TLHLVPGPLS TFTASQTGLV SKDVMAMSSI PMSGILPNHG 1950
LSENPSLSTS LRAITSTLAD VKHTFEKMTT SVTPGTTLPS ILSGATSGSV 2000
ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS TFLTSDMISA 2050
HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY 2100
ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS 2150
TITSSWNRIP TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV 2200
TYPFTATVSS PISSFFETTW LDSTPSFLST EASTSPTATK STVSFYNVEM 2250
SFSVFVEEPR IPITSVINEF TENSLNSIFQ NSEFSLATLE TQIKSRDISE 2300
EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL ASSELMRKIK 2350
SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK 2400
WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE 2450
LPDKIVDLAN ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI 2500
SQCDEISMNL THVMLQIINV VLEKQNNSAS DLHEISNEIL RIIERTGHKM 2550
EFSGQIANLT VAGLALAVLR GDHTFDGMAF SIHSYEEGTD PEIFLGNVPV 2600
GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN VTKALTTYVV 2650
SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN 2700
SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG 2750
CGISSIFLGV AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL 2800
SSFQKVGVCI TAAVALHYFL LVSFTWMGLE AVHMYLALVK VFNIYIPNYI 2850
LKFCLVGWGI PAIMVAITVS VKKDLYGTLS PTTPFCWIKD DSIFYISVVA 2900
YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK GTMSLTFLLG 2950
LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH 3000
LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST 3050
FKSLGSAQGT PSEISFPNDD FDKDPYCSSP 3080
Length:3,080
Mass (Da):333,368
Last modified:September 22, 2009 - v2
Checksum:i3449BC820B251BD3
GO
Isoform 2 (identifier: Q8IZF6-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-63: Missing.
     2243-2381: Missing.
     2593-2637: Missing.
     2979-3012: Missing.
     3069-3080: DDFDKDPYCSSP → APELSALHVVASEPTTG

Show »
Length:2,804
Mass (Da):301,615
Checksum:iB6E45BB089F26D65
GO
Isoform 3 (identifier: Q8IZF6-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     24-24: D → V
     25-229: Missing.

Note: No experimental confirmation available.

Show »
Length:2,875
Mass (Da):309,429
Checksum:iFC26A9AA34552F93
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti276 – 2761I → M.1 Publication
Corresponds to variant rs4829829 [ dbSNP | Ensembl ].
VAR_055929
Natural varianti368 – 3681P → H.1 Publication
Corresponds to variant rs5930931 [ dbSNP | Ensembl ].
VAR_059329
Natural varianti1213 – 12131T → N.
Corresponds to variant rs4829830 [ dbSNP | Ensembl ].
VAR_059330
Natural varianti1540 – 15401S → P.
Corresponds to variant rs912002 [ dbSNP | Ensembl ].
VAR_059331
Natural varianti1791 – 17911F → L.
Corresponds to variant rs5930932 [ dbSNP | Ensembl ].
VAR_059332

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 6363Missing in isoform 2. VSP_038170Add
BLAST
Alternative sequencei24 – 241D → V in isoform 3. VSP_038171
Alternative sequencei25 – 229205Missing in isoform 3. VSP_038172Add
BLAST
Alternative sequencei2243 – 2381139Missing in isoform 2. VSP_038173Add
BLAST
Alternative sequencei2593 – 263745Missing in isoform 2. VSP_038174Add
BLAST
Alternative sequencei2979 – 301234Missing in isoform 2. VSP_038175Add
BLAST
Alternative sequencei3069 – 308012DDFDK…YCSSP → APELSALHVVASEPTTG in isoform 2. VSP_038176Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti229 – 2291Missing in AAN46668. 1 Publication
Sequence conflicti2426 – 24261Missing in AAN46668. 1 Publication
Sequence conflicti2694 – 26941Missing in AAN46668. 1 Publication
Sequence conflicti2769 – 27691Missing in AAN46668. 1 Publication
Sequence conflicti2885 – 28851Missing in AAN46668. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY140954 mRNA. Translation: AAN46668.1.
AY882585 mRNA. Translation: AAW78659.1.
AL161778, AL078638, AL136167 Genomic DNA. Translation: CAM21249.1.
AL078638, AL136167, AL161778 Genomic DNA. Translation: CAM21580.1.
AL136167, AL078638, AL161778 Genomic DNA. Translation: CAM28221.1.
AL161778, AL078638, AL136167 Genomic DNA. Translation: CAI40998.2.
AL078638, AL136167, AL161778 Genomic DNA. Translation: CAM21579.1.
AL136167, AL078638, AL161778 Genomic DNA. Translation: CAM28220.1.
AY255581 mRNA. Translation: AAO85093.1.
CCDSiCCDS35409.1. [Q8IZF6-1]
RefSeqiNP_722576.3. NM_153834.3. [Q8IZF6-1]
XP_005262424.1. XM_005262367.1. [Q8IZF6-3]
UniGeneiHs.381354.

Genome annotation databases

EnsembliENST00000287534; ENSP00000287534; ENSG00000156920. [Q8IZF6-2]
ENST00000370652; ENSP00000359686; ENSG00000156920. [Q8IZF6-1]
ENST00000394141; ENSP00000377697; ENSG00000156920. [Q8IZF6-3]
ENST00000394143; ENSP00000377699; ENSG00000156920. [Q8IZF6-1]
ENST00000412101; ENSP00000416526; ENSG00000156920. [Q8IZF6-3]
GeneIDi139378.
KEGGihsa:139378.
UCSCiuc004ezu.1. human. [Q8IZF6-1]
uc010nsb.1. human. [Q8IZF6-3]
uc010nsc.1. human. [Q8IZF6-2]

Polymorphism databases

DMDMi259016241.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY140954 mRNA. Translation: AAN46668.1 .
AY882585 mRNA. Translation: AAW78659.1 .
AL161778 , AL078638 , AL136167 Genomic DNA. Translation: CAM21249.1 .
AL078638 , AL136167 , AL161778 Genomic DNA. Translation: CAM21580.1 .
AL136167 , AL078638 , AL161778 Genomic DNA. Translation: CAM28221.1 .
AL161778 , AL078638 , AL136167 Genomic DNA. Translation: CAI40998.2 .
AL078638 , AL136167 , AL161778 Genomic DNA. Translation: CAM21579.1 .
AL136167 , AL078638 , AL161778 Genomic DNA. Translation: CAM28220.1 .
AY255581 mRNA. Translation: AAO85093.1 .
CCDSi CCDS35409.1. [Q8IZF6-1 ]
RefSeqi NP_722576.3. NM_153834.3. [Q8IZF6-1 ]
XP_005262424.1. XM_005262367.1. [Q8IZF6-3 ]
UniGenei Hs.381354.

3D structure databases

ProteinModelPortali Q8IZF6.
SMRi Q8IZF6. Positions 2645-2721, 2741-2989.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S63.017.
GPCRDBi Search...

PTM databases

PhosphoSitei Q8IZF6.

Polymorphism databases

DMDMi 259016241.

Proteomic databases

MaxQBi Q8IZF6.
PaxDbi Q8IZF6.
PRIDEi Q8IZF6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000287534 ; ENSP00000287534 ; ENSG00000156920 . [Q8IZF6-2 ]
ENST00000370652 ; ENSP00000359686 ; ENSG00000156920 . [Q8IZF6-1 ]
ENST00000394141 ; ENSP00000377697 ; ENSG00000156920 . [Q8IZF6-3 ]
ENST00000394143 ; ENSP00000377699 ; ENSG00000156920 . [Q8IZF6-1 ]
ENST00000412101 ; ENSP00000416526 ; ENSG00000156920 . [Q8IZF6-3 ]
GeneIDi 139378.
KEGGi hsa:139378.
UCSCi uc004ezu.1. human. [Q8IZF6-1 ]
uc010nsb.1. human. [Q8IZF6-3 ]
uc010nsc.1. human. [Q8IZF6-2 ]

Organism-specific databases

CTDi 139378.
GeneCardsi GC0XP135383.
HGNCi HGNC:18992. GPR112.
HPAi HPA035324.
neXtProti NX_Q8IZF6.
PharmGKBi PA134885132.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000230882.
KOi K08455.
OMAi YFQLWDH.
OrthoDBi EOG7ZGX28.
PhylomeDBi Q8IZF6.
TreeFami TF321769.

Miscellaneous databases

GeneWikii GPR112.
GenomeRNAii 139378.
NextBioi 83952.
PROi Q8IZF6.

Gene expression databases

Bgeei Q8IZF6.
CleanExi HS_GPR112.
Genevestigatori Q8IZF6.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR001759. Pentaxin.
[Graphical view ]
Pfami PF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
PF00354. Pentaxin. 1 hit.
[Graphical view ]
PRINTSi PR00249. GPCRSECRETIN.
SMARTi SM00303. GPS. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
PROSITEi PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions."
    Fredriksson R., Lagerstroem M.C., Hoeglund P.J., Schioeth H.B.
    FEBS Lett. 531:407-414(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
  2. Bonner T.I., Kauffman D., Nagle J.W., Sloger M., Kozhich O.
    Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS MET-276 AND HIS-368.
    Tissue: Retina.
  3. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 343-1613 (ISOFORMS 1/2).
  5. "Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas."
    Leja J., Essaghir A., Essand M., Wester K., Oeberg K., Toetterman T.H., Lloyd R., Vasmatzis G., Demoulin J.-B., Giandomenico V.
    Mod. Pathol. 22:261-272(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiGP112_HUMAN
AccessioniPrimary (citable) accession number: Q8IZF6
Secondary accession number(s): A2A2J1
, A2A2J2, Q5EGP2, Q86SM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: September 22, 2009
Last modified: July 9, 2014
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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