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Q8IZF6

- GP112_HUMAN

UniProt

Q8IZF6 - GP112_HUMAN

Protein

Probable G-protein coupled receptor 112

Gene

GPR112

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
    • BLAST
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 2 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    Orphan receptor.

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: GDB

    GO - Biological processi

    1. G-protein coupled receptor signaling pathway Source: GDB
    2. neuropeptide signaling pathway Source: InterPro

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Protein family/group databases

    MEROPSiS63.017.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable G-protein coupled receptor 112
    Gene namesi
    Name:GPR112
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:18992. GPR112.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: GDB
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134885132.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2727Sequence AnalysisAdd
    BLAST
    Chaini28 – 30803053Probable G-protein coupled receptor 112PRO_0000070335Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi233 – 2331N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi487 – 4871N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi836 – 8361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi899 – 8991N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1020 – 10201N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1519 – 15191N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi2361 – 23611N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi2640 – 26401N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiQ8IZF6.
    PaxDbiQ8IZF6.
    PRIDEiQ8IZF6.

    PTM databases

    PhosphoSiteiQ8IZF6.

    Expressioni

    Tissue specificityi

    Detected in fetal retina. Highly expressed in normal enterochromaffin cells and in neuroendocrine carcinoma. Detected in normal liver; highly expressed in primary liver carcinoma.1 Publication

    Gene expression databases

    BgeeiQ8IZF6.
    CleanExiHS_GPR112.
    GenevestigatoriQ8IZF6.

    Organism-specific databases

    HPAiHPA035324.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IZF6.
    SMRiQ8IZF6. Positions 2645-2721, 2741-2989.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini28 – 27412714ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini2763 – 277816CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini2800 – 28056ExtracellularSequence Analysis
    Topological domaini2827 – 284822CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini2870 – 289223ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini2914 – 294229CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini2964 – 29652ExtracellularSequence Analysis
    Topological domaini2987 – 308094CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei2742 – 276221Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei2779 – 279921Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei2806 – 282621Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei2849 – 286921Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei2893 – 291321Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei2943 – 296321Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei2966 – 298621Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2682 – 273352GPSPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 GPS domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG12793.
    HOGENOMiHOG000230882.
    KOiK08455.
    OMAiYFQLWDH.
    OrthoDBiEOG7ZGX28.
    PhylomeDBiQ8IZF6.
    TreeFamiTF321769.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR017981. GPCR_2-like.
    IPR000832. GPCR_2_secretin-like.
    IPR017983. GPCR_2_secretin-like_CS.
    IPR000203. GPS.
    IPR001759. Pentaxin.
    [Graphical view]
    PfamiPF00002. 7tm_2. 1 hit.
    PF01825. GPS. 1 hit.
    PF00354. Pentaxin. 1 hit.
    [Graphical view]
    PRINTSiPR00249. GPCRSECRETIN.
    SMARTiSM00303. GPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8IZF6-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKEHIIYQKL YGLILMSSFI FLSDTLSLKG KKLDFFGRGD TYVSLIDTIP     50
    ELSRFTACID LVFMDDNSRY WMAFSYITNN ALLGREDIDL GLAGDHQQLI 100
    LYRLGKTFSI RHHLASFQWH TICLIWDGVK GKLELFLNKE RILEVTDQPH 150
    NLTPHGTLFL GHFLKNESSE VKSMMRSFPG SLYYFQLWDH ILENEEFMKC 200
    LDGNIVSWEE DVWLVNKIIP TVDRTLRCFV PENMTIQEKS TTVSQQIDMT 250
    TPSQITGVKP QNTAHSSTLL SQSIPIFATD YTTISYSNTT SPPLETMTAQ 300
    KILKTLVDET ATFAVDVLST SSAISLPTQS ISIDNTTNSM KKTKSPSSES 350
    TKTTKMVEAM ATEIFQPPTP SNFLSTSRFT KNSVVSTTSA IKSQSAVTKT 400
    TSLFSTIEST SMSTTPCLKQ KSTNTGALPI STAGQEFIES TAAGTVPWFT 450
    VEKTSPASTH VGTASSFPPE PVLISTAAPV DSVFPRNQTA FPLATTDMKI 500
    AFTVHSLTLP TRLIETTPAP RTAETELTST NFQDVSLPRV EDAMSTSMSK 550
    ETSSKTFSFL TSFSFTGTES VQTVIDAEAT RTALTPEITL ASTVAETMLS 600
    STITGRVYTQ NTPTADGHLL TLMSTRSAST SKAPESGPTS TTDEAAHLFS 650
    SNETIWTSRP DQALLASMNT TTILTFVPNE NFTSAFHENT TYTEYLSATT 700
    NITPLKASPE GKGTTANDAT TARYTTAVSK LTSPWFANFS IVSGTTSITN 750
    MPEFKLTTLL LKTIPMSTKP ANELPLTPRE TVVPSVDIIS TLACIQPNFS 800
    TEESASETTQ TEINGAIVFG GTTTPVPKSA TTQRLNATVT RKEATSHYLM 850
    RKSTIAAVAE VSPFSTMLEV TDESAQRVTA SVTVSSFPDI EKLSTPLDNK 900
    TATTEVRESW LLTKLVKTTP RSSYNEMTEM FNFNHTYVAH WTSETSEGIS 950
    AGSPTSGSTH IFGEPLGAST TRISETSFST TPTDRTATSL SDGILPPQPT 1000
    AAHSSATPVP VTHMFSLPVN GSSVVAEETE VTMSEPSTLA RAFSTSVLSD 1050
    VSNLSSTTMT TALVPPLDQT ASTTIVIVPT HGDLIRTTSE ATVISVRKTS 1100
    MAVPSLTETP FHSLRLSTPV TAKAETTLFS TSVDTVTPST HTLVCSKPPP 1150
    DNIPPASSTH VISTTSTPEA TQPISQVEET STYALSFPYT FSGGGVVASL 1200
    ATGTTETSVV DETTPSHISA NKLTTSVNSH ISSSATYRVH TPVSIQLVTS 1250
    TSVLSSDKDQ MTISLGKTPR TMEVTEMSPS KNSFISYSRG TPSLEMTDTG 1300
    FPETTKISSH QTHSPSEIPL GTPSDGNLAS SPTSGSTQIT PTLTSSNTVG 1350
    VHIPEMSTSL GKTALPSQAL TITTFLCPEK ESTSALPAYT PRTVEMIVNS 1400
    TYVTHSVSYG QDTSFVDTTT SSSTRISNPM DINTTFSHLH SLRTQPEVTS 1450
    VASFISESTQ TFPESLSLST AGLYNDGFTV LSDRITTAFS VPNVPTMLPR 1500
    ESSMATSTPI YQMSSLPVNV TAFTSKKVSD TPPIVITKSS KTMHPGCLKS 1550
    PCTATSGPMS EMSSIPVNNS AFTPATVSSD TSTRVGLFST LLSSVTPRTT 1600
    MTMQTSTLDV TPVIYAGATS KNKMVSSAFT TEMIEAPSRI TPTTFLSPTE 1650
    PTLPFVKTVP TTIMAGIVTP FVGTTAFSPL SSKSTGAISS IPKTTFSPFL 1700
    SATQQSSQAD EATTLGILSG ITNRSLSTVN SGTGVALTDT YSRITVPENM 1750
    LSPTHADSLH TSFNIQVSPS LTSFKSASGP TKNVKTTTNC FSSNTRKMTS 1800
    LLEKTSLTNY ATSLNTPVSY PPWTPSSATL PSLTSFVYSP HSTEAEISTP 1850
    KTSPPPTSQM VEFPVLGTRM TSSNTQPLLM TSWNIPTAEG SQFPISTTIN 1900
    VPTSNEMETE TLHLVPGPLS TFTASQTGLV SKDVMAMSSI PMSGILPNHG 1950
    LSENPSLSTS LRAITSTLAD VKHTFEKMTT SVTPGTTLPS ILSGATSGSV 2000
    ISKSPILTWL LSSLPSGSPP ATVSNAPHVM TSSTVEVSKS TFLTSDMISA 2050
    HPFTNLTTLP SATMSTILTR TIPTPTLGGI TTGFPTSLPM SINVTDDIVY 2100
    ISTHPEASSR TTITANPRTV SHPSSFSRKT MSPSTTDHTL SVGAMPLPSS 2150
    TITSSWNRIP TASSPSTLII PKPTLDSLLN IMTTTSTVPG ASFPLISTGV 2200
    TYPFTATVSS PISSFFETTW LDSTPSFLST EASTSPTATK STVSFYNVEM 2250
    SFSVFVEEPR IPITSVINEF TENSLNSIFQ NSEFSLATLE TQIKSRDISE 2300
    EEMVMDRAIL EQREGQEMAT ISYVPYSCVC QVIIKASSSL ASSELMRKIK 2350
    SKIHGNFTHG NFTQDQLTLL VNCEHVAVKK LEPGNCKADE TASKYKGTYK 2400
    WLLTNPTETA QTRCIKNEDG NATRFCSISI NTGKSQWEKP KFKQCKLLQE 2450
    LPDKIVDLAN ITISDENAED VAEHILNLIN ESPALGKEET KIIVSKISDI 2500
    SQCDEISMNL THVMLQIINV VLEKQNNSAS DLHEISNEIL RIIERTGHKM 2550
    EFSGQIANLT VAGLALAVLR GDHTFDGMAF SIHSYEEGTD PEIFLGNVPV 2600
    GGILASIYLP KSLTERIPLS NLQTILFNFF GQTSLFKTKN VTKALTTYVV 2650
    SASISDDMFI QNLADPVVIT LQHIGGNQNY GQVHCAFWDF ENNNGLGGWN 2700
    SSGCKVKETN VNYTICQCDH LTHFGVLMDL SRSTVDSVNE QILALITYTG 2750
    CGISSIFLGV AVVTYIAFHK LRKDYPAKIL INLCTALLML NLVFLINSWL 2800
    SSFQKVGVCI TAAVALHYFL LVSFTWMGLE AVHMYLALVK VFNIYIPNYI 2850
    LKFCLVGWGI PAIMVAITVS VKKDLYGTLS PTTPFCWIKD DSIFYISVVA 2900
    YFCLIFLMNL SMFCTVLVQL NSVKSQIQKT RRKMILHDLK GTMSLTFLLG 2950
    LTWGFAFFAW GPMRNFFLYL FAIFNTLQGF FIFVFHCVMK ESVREQWQIH 3000
    LCCGWLRLDN SSDGSSRCQI KVGYKQEGLK KIFEHKLLTP SLKSTATSST 3050
    FKSLGSAQGT PSEISFPNDD FDKDPYCSSP 3080
    Length:3,080
    Mass (Da):333,368
    Last modified:September 22, 2009 - v2
    Checksum:i3449BC820B251BD3
    GO
    Isoform 2 (identifier: Q8IZF6-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-63: Missing.
         2243-2381: Missing.
         2593-2637: Missing.
         2979-3012: Missing.
         3069-3080: DDFDKDPYCSSP → APELSALHVVASEPTTG

    Show »
    Length:2,804
    Mass (Da):301,615
    Checksum:iB6E45BB089F26D65
    GO
    Isoform 3 (identifier: Q8IZF6-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         24-24: D → V
         25-229: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:2,875
    Mass (Da):309,429
    Checksum:iFC26A9AA34552F93
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti229 – 2291Missing in AAN46668. (PubMed:12435584)Curated
    Sequence conflicti2426 – 24261Missing in AAN46668. (PubMed:12435584)Curated
    Sequence conflicti2694 – 26941Missing in AAN46668. (PubMed:12435584)Curated
    Sequence conflicti2769 – 27691Missing in AAN46668. (PubMed:12435584)Curated
    Sequence conflicti2885 – 28851Missing in AAN46668. (PubMed:12435584)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti276 – 2761I → M.1 Publication
    Corresponds to variant rs4829829 [ dbSNP | Ensembl ].
    VAR_055929
    Natural varianti368 – 3681P → H.1 Publication
    Corresponds to variant rs5930931 [ dbSNP | Ensembl ].
    VAR_059329
    Natural varianti1213 – 12131T → N.
    Corresponds to variant rs4829830 [ dbSNP | Ensembl ].
    VAR_059330
    Natural varianti1540 – 15401S → P.
    Corresponds to variant rs912002 [ dbSNP | Ensembl ].
    VAR_059331
    Natural varianti1791 – 17911F → L.
    Corresponds to variant rs5930932 [ dbSNP | Ensembl ].
    VAR_059332

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 6363Missing in isoform 2. 1 PublicationVSP_038170Add
    BLAST
    Alternative sequencei24 – 241D → V in isoform 3. CuratedVSP_038171
    Alternative sequencei25 – 229205Missing in isoform 3. CuratedVSP_038172Add
    BLAST
    Alternative sequencei2243 – 2381139Missing in isoform 2. 1 PublicationVSP_038173Add
    BLAST
    Alternative sequencei2593 – 263745Missing in isoform 2. 1 PublicationVSP_038174Add
    BLAST
    Alternative sequencei2979 – 301234Missing in isoform 2. 1 PublicationVSP_038175Add
    BLAST
    Alternative sequencei3069 – 308012DDFDK…YCSSP → APELSALHVVASEPTTG in isoform 2. 1 PublicationVSP_038176Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY140954 mRNA. Translation: AAN46668.1.
    AY882585 mRNA. Translation: AAW78659.1.
    AL161778, AL078638, AL136167 Genomic DNA. Translation: CAM21249.1.
    AL078638, AL136167, AL161778 Genomic DNA. Translation: CAM21580.1.
    AL136167, AL078638, AL161778 Genomic DNA. Translation: CAM28221.1.
    AL161778, AL078638, AL136167 Genomic DNA. Translation: CAI40998.2.
    AL078638, AL136167, AL161778 Genomic DNA. Translation: CAM21579.1.
    AL136167, AL078638, AL161778 Genomic DNA. Translation: CAM28220.1.
    AY255581 mRNA. Translation: AAO85093.1.
    CCDSiCCDS35409.1. [Q8IZF6-1]
    RefSeqiNP_722576.3. NM_153834.3. [Q8IZF6-1]
    XP_005262424.1. XM_005262367.1. [Q8IZF6-3]
    UniGeneiHs.381354.

    Genome annotation databases

    EnsembliENST00000370652; ENSP00000359686; ENSG00000156920. [Q8IZF6-1]
    ENST00000394141; ENSP00000377697; ENSG00000156920. [Q8IZF6-3]
    ENST00000394143; ENSP00000377699; ENSG00000156920. [Q8IZF6-1]
    GeneIDi139378.
    KEGGihsa:139378.
    UCSCiuc004ezu.1. human. [Q8IZF6-1]
    uc010nsb.1. human. [Q8IZF6-3]
    uc010nsc.1. human. [Q8IZF6-2]

    Polymorphism databases

    DMDMi259016241.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY140954 mRNA. Translation: AAN46668.1 .
    AY882585 mRNA. Translation: AAW78659.1 .
    AL161778 , AL078638 , AL136167 Genomic DNA. Translation: CAM21249.1 .
    AL078638 , AL136167 , AL161778 Genomic DNA. Translation: CAM21580.1 .
    AL136167 , AL078638 , AL161778 Genomic DNA. Translation: CAM28221.1 .
    AL161778 , AL078638 , AL136167 Genomic DNA. Translation: CAI40998.2 .
    AL078638 , AL136167 , AL161778 Genomic DNA. Translation: CAM21579.1 .
    AL136167 , AL078638 , AL161778 Genomic DNA. Translation: CAM28220.1 .
    AY255581 mRNA. Translation: AAO85093.1 .
    CCDSi CCDS35409.1. [Q8IZF6-1 ]
    RefSeqi NP_722576.3. NM_153834.3. [Q8IZF6-1 ]
    XP_005262424.1. XM_005262367.1. [Q8IZF6-3 ]
    UniGenei Hs.381354.

    3D structure databases

    ProteinModelPortali Q8IZF6.
    SMRi Q8IZF6. Positions 2645-2721, 2741-2989.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S63.017.
    GPCRDBi Search...

    PTM databases

    PhosphoSitei Q8IZF6.

    Polymorphism databases

    DMDMi 259016241.

    Proteomic databases

    MaxQBi Q8IZF6.
    PaxDbi Q8IZF6.
    PRIDEi Q8IZF6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000370652 ; ENSP00000359686 ; ENSG00000156920 . [Q8IZF6-1 ]
    ENST00000394141 ; ENSP00000377697 ; ENSG00000156920 . [Q8IZF6-3 ]
    ENST00000394143 ; ENSP00000377699 ; ENSG00000156920 . [Q8IZF6-1 ]
    GeneIDi 139378.
    KEGGi hsa:139378.
    UCSCi uc004ezu.1. human. [Q8IZF6-1 ]
    uc010nsb.1. human. [Q8IZF6-3 ]
    uc010nsc.1. human. [Q8IZF6-2 ]

    Organism-specific databases

    CTDi 139378.
    GeneCardsi GC0XP135383.
    HGNCi HGNC:18992. GPR112.
    HPAi HPA035324.
    neXtProti NX_Q8IZF6.
    PharmGKBi PA134885132.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG12793.
    HOGENOMi HOG000230882.
    KOi K08455.
    OMAi YFQLWDH.
    OrthoDBi EOG7ZGX28.
    PhylomeDBi Q8IZF6.
    TreeFami TF321769.

    Miscellaneous databases

    GeneWikii GPR112.
    GenomeRNAii 139378.
    NextBioi 83952.
    PROi Q8IZF6.

    Gene expression databases

    Bgeei Q8IZF6.
    CleanExi HS_GPR112.
    Genevestigatori Q8IZF6.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR017981. GPCR_2-like.
    IPR000832. GPCR_2_secretin-like.
    IPR017983. GPCR_2_secretin-like_CS.
    IPR000203. GPS.
    IPR001759. Pentaxin.
    [Graphical view ]
    Pfami PF00002. 7tm_2. 1 hit.
    PF01825. GPS. 1 hit.
    PF00354. Pentaxin. 1 hit.
    [Graphical view ]
    PRINTSi PR00249. GPCRSECRETIN.
    SMARTi SM00303. GPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    PS50221. GPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions."
      Fredriksson R., Lagerstroem M.C., Hoeglund P.J., Schioeth H.B.
      FEBS Lett. 531:407-414(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    2. Bonner T.I., Kauffman D., Nagle J.W., Sloger M., Kozhich O.
      Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS MET-276 AND HIS-368.
      Tissue: Retina.
    3. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 343-1613 (ISOFORMS 1/2).
    5. "Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas."
      Leja J., Essaghir A., Essand M., Wester K., Oeberg K., Toetterman T.H., Lloyd R., Vasmatzis G., Demoulin J.-B., Giandomenico V.
      Mod. Pathol. 22:261-272(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiGP112_HUMAN
    AccessioniPrimary (citable) accession number: Q8IZF6
    Secondary accession number(s): A2A2J1
    , A2A2J2, Q5EGP2, Q86SM6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 31, 2004
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 100 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3