ID   AGRF3_HUMAN             Reviewed;        1079 AA.
AC   Q8IZF5; B4DF15; E9PEV1; Q53TA5; Q6UXT7; Q6UXX3; Q86SL7; Q8IXD8; Q8TDT3;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 170.
DE   RecName: Full=Adhesion G-protein coupled receptor F3;
DE   AltName: Full=G-protein coupled receptor 113;
DE   AltName: Full=G-protein coupled receptor PGR23;
DE   Flags: Precursor;
GN   Name=ADGRF3; Synonyms=GPR113, PGR23; ORFNames=UNQ9196/PRO34000;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RX   PubMed=12435584; DOI=10.1016/s0014-5793(02)03574-3;
RA   Fredriksson R., Lagerstroem M.C., Hoeglund P.J., Schioeth H.B.;
RT   "Novel human G protein-coupled receptors with long N-terminals containing
RT   GPS domains and Ser/Thr-rich regions.";
RL   FEBS Lett. 531:407-414(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,
RA   Tsutsumi S., Aburatani H., Asai K., Akiyama Y.;
RT   "Genome-wide discovery and analysis of human seven transmembrane helix
RT   receptor genes.";
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), AND VARIANT THR-404.
RX   PubMed=12975309; DOI=10.1101/gr.1293003;
RA   Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA   Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA   Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA   Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA   Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA   Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA   Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA   Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT   "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT   identify novel human secreted and transmembrane proteins: a bioinformatics
RT   assessment.";
RL   Genome Res. 13:2265-2270(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC   TISSUE=Cerebellum;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 563-1079.
RX   PubMed=12044878; DOI=10.1016/s0014-5793(02)02775-8;
RA   Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.;
RT   "Identification of G protein-coupled receptor genes from the human genome
RT   sequence.";
RL   FEBS Lett. 520:97-101(2002).
RN   [7]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 797-942.
RX   PubMed=12679517; DOI=10.1073/pnas.0230374100;
RA   Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E.,
RA   Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C.,
RA   Bergmann J.E., Gaitanaris G.A.;
RT   "The G protein-coupled receptor repertoires of human and mouse.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
RN   [8]
RP   NOMENCLATURE.
RX   PubMed=25713288; DOI=10.1124/pr.114.009647;
RA   Hamann J., Aust G., Arac D., Engel F.B., Formstone C., Fredriksson R.,
RA   Hall R.A., Harty B.L., Kirchhoff C., Knapp B., Krishnan A., Liebscher I.,
RA   Lin H.H., Martinelli D.C., Monk K.R., Peeters M.C., Piao X., Promel S.,
RA   Schoneberg T., Schwartz T.W., Singer K., Stacey M., Ushkaryov Y.A.,
RA   Vallon M., Wolfrum U., Wright M.W., Xu L., Langenhan T., Schioth H.B.;
RT   "International union of basic and clinical pharmacology. XCIV. Adhesion G
RT   protein-coupled receptors.";
RL   Pharmacol. Rev. 67:338-367(2015).
CC   -!- FUNCTION: Orphan receptor.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q8IZF5-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8IZF5-2; Sequence=VSP_012815, VSP_012816, VSP_012817;
CC       Name=3;
CC         IsoId=Q8IZF5-3; Sequence=VSP_046174, VSP_046175;
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family.
CC       Adhesion G-protein coupled receptor (ADGR) subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB89332.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAC45265.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AY140955; AAN46669.1; -; mRNA.
DR   EMBL; AB065959; BAC45265.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AY358172; AAQ88539.1; -; mRNA.
DR   EMBL; AY358214; AAQ88581.1; -; Transcribed_RNA.
DR   EMBL; AB083619; BAB89332.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AK293887; BAG57276.1; -; mRNA.
DR   EMBL; AC010896; AAY14645.1; -; Genomic_DNA.
DR   EMBL; AY255611; AAO85123.1; -; mRNA.
DR   CCDS; CCDS33159.2; -. [Q8IZF5-2]
DR   CCDS; CCDS46238.1; -. [Q8IZF5-3]
DR   CCDS; CCDS46239.1; -. [Q8IZF5-1]
DR   RefSeq; NP_001138640.1; NM_001145168.1. [Q8IZF5-1]
DR   RefSeq; NP_001138641.1; NM_001145169.1. [Q8IZF5-3]
DR   RefSeq; NP_001308900.1; NM_001321971.1.
DR   RefSeq; NP_001308904.1; NM_001321975.1.
DR   RefSeq; NP_722577.2; NM_153835.3. [Q8IZF5-2]
DR   AlphaFoldDB; Q8IZF5; -.
DR   SMR; Q8IZF5; -.
DR   BioGRID; 127907; 20.
DR   STRING; 9606.ENSP00000307831; -.
DR   ChEMBL; CHEMBL4523891; -.
DR   MEROPS; P02.028; -.
DR   GlyCosmos; Q8IZF5; 6 sites, No reported glycans.
DR   GlyGen; Q8IZF5; 6 sites.
DR   iPTMnet; Q8IZF5; -.
DR   PhosphoSitePlus; Q8IZF5; -.
DR   BioMuta; ADGRF3; -.
DR   DMDM; 59797951; -.
DR   MassIVE; Q8IZF5; -.
DR   MaxQB; Q8IZF5; -.
DR   PaxDb; 9606-ENSP00000307831; -.
DR   Antibodypedia; 52007; 100 antibodies from 22 providers.
DR   DNASU; 165082; -.
DR   Ensembl; ENST00000311519.5; ENSP00000307831.1; ENSG00000173567.16. [Q8IZF5-1]
DR   Ensembl; ENST00000333478.10; ENSP00000327396.6; ENSG00000173567.16. [Q8IZF5-2]
DR   Ensembl; ENST00000421160.6; ENSP00000388537.2; ENSG00000173567.16. [Q8IZF5-3]
DR   Ensembl; ENST00000447444.5; ENSP00000404775.1; ENSG00000173567.16. [Q8IZF5-2]
DR   GeneID; 165082; -.
DR   KEGG; hsa:165082; -.
DR   UCSC; uc002rhd.2; human. [Q8IZF5-1]
DR   AGR; HGNC:18989; -.
DR   CTD; 165082; -.
DR   DisGeNET; 165082; -.
DR   GeneCards; ADGRF3; -.
DR   HGNC; HGNC:18989; ADGRF3.
DR   HPA; ENSG00000173567; Tissue enhanced (pancreas).
DR   neXtProt; NX_Q8IZF5; -.
DR   OpenTargets; ENSG00000173567; -.
DR   PharmGKB; PA134918027; -.
DR   VEuPathDB; HostDB:ENSG00000173567; -.
DR   eggNOG; KOG4193; Eukaryota.
DR   GeneTree; ENSGT00940000161541; -.
DR   HOGENOM; CLU_010357_0_0_1; -.
DR   InParanoid; Q8IZF5; -.
DR   OMA; YQWNASV; -.
DR   OrthoDB; 4097004at2759; -.
DR   PhylomeDB; Q8IZF5; -.
DR   TreeFam; TF316380; -.
DR   PathwayCommons; Q8IZF5; -.
DR   BioGRID-ORCS; 165082; 15 hits in 1144 CRISPR screens.
DR   GeneWiki; GPR113; -.
DR   GenomeRNAi; 165082; -.
DR   Pharos; Q8IZF5; Tdark.
DR   PRO; PR:Q8IZF5; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   RNAct; Q8IZF5; Protein.
DR   Bgee; ENSG00000173567; Expressed in male germ line stem cell (sensu Vertebrata) in testis and 94 other cell types or tissues.
DR   ExpressionAtlas; Q8IZF5; baseline and differential.
DR   GO; GO:0016020; C:membrane; TAS:GDB.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR   GO; GO:0007189; P:adenylate cyclase-activating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; TAS:GDB.
DR   CDD; cd15253; 7tmB2_GPR113; 1.
DR   Gene3D; 2.60.220.50; -; 1.
DR   Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR046338; GAIN_dom_sf.
DR   InterPro; IPR017981; GPCR_2-like_7TM.
DR   InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR   InterPro; IPR001879; GPCR_2_extracellular_dom.
DR   InterPro; IPR000832; GPCR_2_secretin-like.
DR   InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR   InterPro; IPR000203; GPS.
DR   PANTHER; PTHR45813:SF2; ADHESION G-PROTEIN COUPLED RECEPTOR F3; 1.
DR   PANTHER; PTHR45813; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00002; 7tm_2; 1.
DR   Pfam; PF01825; GPS; 1.
DR   Pfam; PF02793; HRM; 1.
DR   PRINTS; PR00249; GPCRSECRETIN.
DR   SMART; SM00303; GPS; 1.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   SUPFAM; SSF111418; Hormone receptor domain; 1.
DR   PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR   PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR   PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR   PROSITE; PS50221; GPS; 1.
DR   Genevisible; Q8IZF5; HS.
PE   2: Evidence at transcript level;
KW   Alternative splicing; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Receptor; Reference proteome; Signal; Transducer; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..1079
FT                   /note="Adhesion G-protein coupled receptor F3"
FT                   /id="PRO_0000012893"
FT   TOPO_DOM        26..775
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        776..796
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        797..811
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        812..832
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        833..851
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        852..874
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        875..881
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        882..902
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        903..928
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        929..949
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        950..973
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        974..994
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        995..1002
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        1003..1023
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        1024..1079
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   DOMAIN          712..764
FT                   /note="GPS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00098"
FT   CARBOHYD        188
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        264
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        301
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        382
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        441
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        648
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..97
FT                   /note="MVCSAAPLLLLATTLPLLGSPVAQASQPVSETGVRPREGLQRRQWGPLIGRD
FT                   KAWNERIDRPFPACPIPLSSSFGRWPKGQTMWAQTSTLTLTEEEL -> MTTRKLSAHS
FT                   AATPGYKAVTHKHHTGWARMAKTGLPEK (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12975309"
FT                   /id="VSP_012815"
FT   VAR_SEQ         29..97
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_046174"
FT   VAR_SEQ         168..307
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12975309"
FT                   /id="VSP_012816"
FT   VAR_SEQ         1048..1079
FT                   /note="VSCCLQILSCASKSMSEGIPWPSSEDMGTARS -> ATNEGCILEHSKGGSD
FT                   TARKTDASE (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12975309"
FT                   /id="VSP_012817"
FT   VAR_SEQ         1048..1079
FT                   /note="VSCCLQILSCASKSMSEGIPWPSSEDMGTARS -> ATNEGCILEHSKGGSD
FT                   TAR (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_046175"
FT   VARIANT         404
FT                   /note="A -> T (in dbSNP:rs2052937)"
FT                   /evidence="ECO:0000269|PubMed:12975309"
FT                   /id="VAR_024475"
FT   CONFLICT        348
FT                   /note="A -> V (in Ref. 3; AAQ88539)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        599
FT                   /note="H -> Y (in Ref. 3; AAQ88539)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        765
FT                   /note="P -> S (in Ref. 4; BAG57276)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        886
FT                   /note="M -> T (in Ref. 3; AAQ88581)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        Q8IZF5-2:868
FT                   /note="K -> N (in Ref. 3; AAQ88581)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1079 AA;  116341 MW;  A18CA158F4DDBB9C CRC64;
     MVCSAAPLLL LATTLPLLGS PVAQASQPVS ETGVRPREGL QRRQWGPLIG RDKAWNERID
     RPFPACPIPL SSSFGRWPKG QTMWAQTSTL TLTEEELGQS QAGGESGSGQ LLDQENGAGE
     SALVSVYVHL DFPDKTWPPE LSRTLTLPAA SASSSPRPLL TGLRLTTECN VNHKGNFYCA
     CLSGYQWNTS ICLHYPPCQS LHNHQPCGCL VFSHPEPGYC QLLPPGSPVT CLPAVPGILN
     LNSQLQMPGD TLSLTLHLSQ EATNLSWFLR HPGSPSPILL QPGTQVSVTS SHGQAALSVS
     NMSHHWAGEY MSCFEAQGFK WNLYEVVRVP LKATDVARLP YQLSISCATS PGFQLSCCIP
     STNLAYTAAW SPGEGSKASS FNESGSQCFV LAVQRCPMAD TTYACDLQSL GLAPLRVPIS
     ITIIQDGDIT CPEDASVLTW NVTKAGHVAQ APCPESKRGI VRRLCGADGV WGPVHSSCTD
     ARLLALFTRT KLLQAGQGSP AEEVPQILAQ LPGQAAEASS PSDLLTLLST MKYVAKVVAE
     ARIQLDRRAL KNLLIATDKV LDMDTRSLWT LAQARKPWAG STLLLAVETL ACSLCPQDHP
     FAFSLPNVLL QSQLFGPTFP ADYSISFPTR PPLQAQIPRH SLAPLVRNGT EISITSLVLR
     KLDHLLPSNY GQGLGDSLYA TPGLVLVISI MAGDRAFSQG EVIMDFGNTD GSPHCVFWDH
     SLFQGRGGWS KEGCQAQVAS ASPTAQCLCQ HLTAFSVLMS PHTVPEEPAL ALLTQVGLGA
     SILALLVCLG VYWLVWRVVV RNKISYFRHA ALLNMVFCLL AADTCFLGAP FLSPGPRSPL
     CLAAAFLCHF LYLATFFWML AQALVLAHQL LFVFHQLAKH RVLPLMVLLG YLCPLGLAGV
     TLGLYLPQGQ YLREGECWLD GKGGALYTFV GPVLAIIGVN GLVLAMAMLK LLRPSLSEGP
     PAEKRQALLG VIKALLILTP IFGLTWGLGL ATLLEEVSTV PHYIFTILNT LQGVFILLFG
     CLMDRKIQEA LRKRFCRAQA PSSTISLVSC CLQILSCASK SMSEGIPWPS SEDMGTARS
//