Q8IZF5 (GP113_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable G-protein coupled receptor 113

Alternative name(s):
G-protein coupled receptor PGR23

Gene names

Name:	GPR113
Synonyms:	PGR23
ORF Names:	UNQ9196/PRO34000

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1079 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Orphan receptor.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain.
Sequence caution	The sequence BAB89332.1 differs from that shown. Reason: Erroneous initiation. The sequence BAC45265.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Signal Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Traceable author statement PubMed 15203201. Source: GDB plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Traceable author statement PubMed 15203201. Source: GDB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8IZF5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8IZF5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: MVCSAAPLLL...STLTLTEEEL → MTTRKLSAHS...RMAKTGLPEK
     168-307: Missing.
     1048-1079: VSCCLQILSCASKSMSEGIPWPSSEDMGTARS → ATNEGCILEHSKGGSDTARKTDASE

Isoform 3 (identifier: Q8IZF5-3)

The sequence of this isoform differs from the canonical sequence as follows:
     29-97: Missing.
     1048-1079: VSCCLQILSCASKSMSEGIPWPSSEDMGTARS → ATNEGCILEHSKGGSDTAR

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 1079	1054	Probable G-protein coupled receptor 113		PRO_0000012893
Regions
	Topological domain	26 – 775	750	Extracellular Potential
	Transmembrane	776 – 796	21	Helical; Name=1; Potential
	Topological domain	797 – 811	15	Cytoplasmic Potential
	Transmembrane	812 – 832	21	Helical; Name=2; Potential
	Topological domain	833 – 851	19	Extracellular Potential
	Transmembrane	852 – 874	23	Helical; Name=3; Potential
	Topological domain	875 – 881	7	Cytoplasmic Potential
	Transmembrane	882 – 902	21	Helical; Name=4; Potential
	Topological domain	903 – 928	26	Extracellular Potential
	Transmembrane	929 – 949	21	Helical; Name=5; Potential
	Topological domain	950 – 973	24	Cytoplasmic Potential
	Transmembrane	974 – 994	21	Helical; Name=6; Potential
	Topological domain	995 – 1002	8	Extracellular Potential
	Transmembrane	1003 – 1023	21	Helical; Name=7; Potential
	Topological domain	1024 – 1079	56	Cytoplasmic Potential
	Domain	712 – 764	53	GPS
Amino acid modifications
	Glycosylation	188	1	N-linked (GlcNAc...) Potential
	Glycosylation	264	1	N-linked (GlcNAc...) Potential
	Glycosylation	301	1	N-linked (GlcNAc...) Potential
	Glycosylation	382	1	N-linked (GlcNAc...) Potential
	Glycosylation	441	1	N-linked (GlcNAc...) Potential
	Glycosylation	648	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 97	97	MVCSA…TEEEL → MTTRKLSAHSAATPGYKAVT HKHHTGWARMAKTGLPEK in isoform 2.		VSP_012815
	Alternative sequence	29 – 97	69	Missing in isoform 3.		VSP_046174
	Alternative sequence	168 – 307	140	Missing in isoform 2.		VSP_012816
	Alternative sequence	1048 – 1079	32	VSCCL…GTARS → ATNEGCILEHSKGGSDTARK TDASE in isoform 2.		VSP_012817
	Alternative sequence	1048 – 1079	32	VSCCL…GTARS → ATNEGCILEHSKGGSDTAR in isoform 3.		VSP_046175
	Natural variant	404	1	A → T. Ref.3 Corresponds to variant rs2052937 [ dbSNP | Ensembl ].		VAR_024475
Experimental info
	Sequence conflict	348	1	A → V in AAQ88539. Ref.3
	Sequence conflict	599	1	H → Y in AAQ88539. Ref.3
	Sequence conflict	765	1	P → S in BAG57276. Ref.4
	Sequence conflict	886	1	M → T in AAQ88581. Ref.3
Isoform 2:
	Sequence conflict	868	1	K → N in AAQ88581. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: A18CA158F4DDBB9C	FASTA	1,079	116,341
	10 20 30 40 50 60 MVCSAAPLLL LATTLPLLGS PVAQASQPVS ETGVRPREGL QRRQWGPLIG RDKAWNERID 70 80 90 100 110 120 RPFPACPIPL SSSFGRWPKG QTMWAQTSTL TLTEEELGQS QAGGESGSGQ LLDQENGAGE 130 140 150 160 170 180 SALVSVYVHL DFPDKTWPPE LSRTLTLPAA SASSSPRPLL TGLRLTTECN VNHKGNFYCA 190 200 210 220 230 240 CLSGYQWNTS ICLHYPPCQS LHNHQPCGCL VFSHPEPGYC QLLPPGSPVT CLPAVPGILN 250 260 270 280 290 300 LNSQLQMPGD TLSLTLHLSQ EATNLSWFLR HPGSPSPILL QPGTQVSVTS SHGQAALSVS 310 320 330 340 350 360 NMSHHWAGEY MSCFEAQGFK WNLYEVVRVP LKATDVARLP YQLSISCATS PGFQLSCCIP 370 380 390 400 410 420 STNLAYTAAW SPGEGSKASS FNESGSQCFV LAVQRCPMAD TTYACDLQSL GLAPLRVPIS 430 440 450 460 470 480 ITIIQDGDIT CPEDASVLTW NVTKAGHVAQ APCPESKRGI VRRLCGADGV WGPVHSSCTD 490 500 510 520 530 540 ARLLALFTRT KLLQAGQGSP AEEVPQILAQ LPGQAAEASS PSDLLTLLST MKYVAKVVAE 550 560 570 580 590 600 ARIQLDRRAL KNLLIATDKV LDMDTRSLWT LAQARKPWAG STLLLAVETL ACSLCPQDHP 610 620 630 640 650 660 FAFSLPNVLL QSQLFGPTFP ADYSISFPTR PPLQAQIPRH SLAPLVRNGT EISITSLVLR 670 680 690 700 710 720 KLDHLLPSNY GQGLGDSLYA TPGLVLVISI MAGDRAFSQG EVIMDFGNTD GSPHCVFWDH 730 740 750 760 770 780 SLFQGRGGWS KEGCQAQVAS ASPTAQCLCQ HLTAFSVLMS PHTVPEEPAL ALLTQVGLGA 790 800 810 820 830 840 SILALLVCLG VYWLVWRVVV RNKISYFRHA ALLNMVFCLL AADTCFLGAP FLSPGPRSPL 850 860 870 880 890 900 CLAAAFLCHF LYLATFFWML AQALVLAHQL LFVFHQLAKH RVLPLMVLLG YLCPLGLAGV 910 920 930 940 950 960 TLGLYLPQGQ YLREGECWLD GKGGALYTFV GPVLAIIGVN GLVLAMAMLK LLRPSLSEGP 970 980 990 1000 1010 1020 PAEKRQALLG VIKALLILTP IFGLTWGLGL ATLLEEVSTV PHYIFTILNT LQGVFILLFG 1030 1040 1050 1060 1070 CLMDRKIQEA LRKRFCRAQA PSSTISLVSC CLQILSCASK SMSEGIPWPS SEDMGTARS
	Isoform 2 [UniParc]. Checksum: 03A8E3E3AEEDE1C8	FASTA	873	93,912
	10 20 30 40 50 60 MTTRKLSAHS AATPGYKAVT HKHHTGWARM AKTGLPEKGQ SQAGGESGSG QLLDQENGAG 70 80 90 100 110 120 ESALVSVYVH LDFPDKTWPP ELSRTLTLPA ASASSSPRPL LTGLRLTTGE YMSCFEAQGF 130 140 150 160 170 180 KWNLYEVVRV PLKATDVARL PYQLSISCAT SPGFQLSCCI PSTNLAYTAA WSPGEGSKAS 190 200 210 220 230 240 SFNESGSQCF VLAVQRCPMA DTTYACDLQS LGLAPLRVPI SITIIQDGDI TCPEDASVLT 250 260 270 280 290 300 WNVTKAGHVA QAPCPESKRG IVRRLCGADG VWGPVHSSCT DARLLALFTR TKLLQAGQGS 310 320 330 340 350 360 PAEEVPQILA QLPGQAAEAS SPSDLLTLLS TMKYVAKVVA EARIQLDRRA LKNLLIATDK 370 380 390 400 410 420 VLDMDTRSLW TLAQARKPWA GSTLLLAVET LACSLCPQDH PFAFSLPNVL LQSQLFGPTF 430 440 450 460 470 480 PADYSISFPT RPPLQAQIPR HSLAPLVRNG TEISITSLVL RKLDHLLPSN YGQGLGDSLY 490 500 510 520 530 540 ATPGLVLVIS IMAGDRAFSQ GEVIMDFGNT DGSPHCVFWD HSLFQGRGGW SKEGCQAQVA 550 560 570 580 590 600 SASPTAQCLC QHLTAFSVLM SPHTVPEEPA LALLTQVGLG ASILALLVCL GVYWLVWRVV 610 620 630 640 650 660 VRNKISYFRH AALLNMVFCL LAADTCFLGA PFLSPGPRSP LCLAAAFLCH FLYLATFFWM 670 680 690 700 710 720 LAQALVLAHQ LLFVFHQLAK HRVLPLMVLL GYLCPLGLAG VTLGLYLPQG QYLREGECWL 730 740 750 760 770 780 DGKGGALYTF VGPVLAIIGV NGLVLAMAML KLLRPSLSEG PPAEKRQALL GVIKALLILT 790 800 810 820 830 840 PIFGLTWGLG LATLLEEVST VPHYIFTILN TLQGVFILLF GCLMDRKIQE ALRKRFCRAQ 850 860 870 APSSTISLAT NEGCILEHSK GGSDTARKTD ASE
	Isoform 3 [UniParc]. Checksum: 3319FE1B2BBDB3B3	FASTA	997	107,020
	10 20 30 40 50 60 MVCSAAPLLL LATTLPLLGS PVAQASQPGQ SQAGGESGSG QLLDQENGAG ESALVSVYVH 70 80 90 100 110 120 LDFPDKTWPP ELSRTLTLPA ASASSSPRPL LTGLRLTTEC NVNHKGNFYC ACLSGYQWNT 130 140 150 160 170 180 SICLHYPPCQ SLHNHQPCGC LVFSHPEPGY CQLLPPGSPV TCLPAVPGIL NLNSQLQMPG 190 200 210 220 230 240 DTLSLTLHLS QEATNLSWFL RHPGSPSPIL LQPGTQVSVT SSHGQAALSV SNMSHHWAGE 250 260 270 280 290 300 YMSCFEAQGF KWNLYEVVRV PLKATDVARL PYQLSISCAT SPGFQLSCCI PSTNLAYTAA 310 320 330 340 350 360 WSPGEGSKAS SFNESGSQCF VLAVQRCPMA DTTYACDLQS LGLAPLRVPI SITIIQDGDI 370 380 390 400 410 420 TCPEDASVLT WNVTKAGHVA QAPCPESKRG IVRRLCGADG VWGPVHSSCT DARLLALFTR 430 440 450 460 470 480 TKLLQAGQGS PAEEVPQILA QLPGQAAEAS SPSDLLTLLS TMKYVAKVVA EARIQLDRRA 490 500 510 520 530 540 LKNLLIATDK VLDMDTRSLW TLAQARKPWA GSTLLLAVET LACSLCPQDH PFAFSLPNVL 550 560 570 580 590 600 LQSQLFGPTF PADYSISFPT RPPLQAQIPR HSLAPLVRNG TEISITSLVL RKLDHLLPSN 610 620 630 640 650 660 YGQGLGDSLY ATPGLVLVIS IMAGDRAFSQ GEVIMDFGNT DGSPHCVFWD HSLFQGRGGW 670 680 690 700 710 720 SKEGCQAQVA SASPTAQCLC QHLTAFSVLM SPHTVPEEPA LALLTQVGLG ASILALLVCL 730 740 750 760 770 780 GVYWLVWRVV VRNKISYFRH AALLNMVFCL LAADTCFLGA PFLSPGPRSP LCLAAAFLCH 790 800 810 820 830 840 FLYLATFFWM LAQALVLAHQ LLFVFHQLAK HRVLPLMVLL GYLCPLGLAG VTLGLYLPQG 850 860 870 880 890 900 QYLREGECWL DGKGGALYTF VGPVLAIIGV NGLVLAMAML KLLRPSLSEG PPAEKRQALL 910 920 930 940 950 960 GVIKALLILT PIFGLTWGLG LATLLEEVST VPHYIFTILN TLQGVFILLF GCLMDRKIQE 970 980 990 ALRKRFCRAQ APSSTISLAT NEGCILEHSK GGSDTAR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions." Fredriksson R., Lagerstroem M.C., Hoeglund P.J., Schioeth H.B. FEBS Lett. 531:407-414(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]	"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes." Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M. Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT THR-404.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Cerebellum.
[5]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"Identification of G protein-coupled receptor genes from the human genome sequence." Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S. FEBS Lett. 520:97-101(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 563-1079.
[7]	"The G protein-coupled receptor repertoires of human and mouse." Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E., Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C., Bergmann J.E., Gaitanaris G.A. Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 797-942.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY140955 mRNA. Translation: AAN46669.1. AB065959 Genomic DNA. Translation: BAC45265.1. Sequence problems. AY358172 mRNA. Translation: AAQ88539.1. AY358214 Transcribed RNA. Translation: AAQ88581.1. AB083619 Genomic DNA. Translation: BAB89332.1. Different initiation. AK293887 mRNA. Translation: BAG57276.1. AC010896 Genomic DNA. Translation: AAY14645.1. AY255611 mRNA. Translation: AAO85123.1.
IPI	IPI00218000. IPI00553242. IPI00852794.
RefSeq	NP_001138640.1. NM_001145168.1. NP_001138641.1. NM_001145169.1. NP_722577.2. NM_153835.3.
UniGene	Hs.631878.
3D structure databases
ProteinModelPortal	Q8IZF5.
ModBase	Search...
Protein family/group databases
MEROPS	S63.031.
GPCRDB	Search...
PTM databases
PhosphoSite	Q8IZF5.
Polymorphism databases
DMDM	59797951.
Proteomic databases
PaxDb	Q8IZF5.
PRIDE	Q8IZF5.
Protocols and materials databases
DNASU	165082.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000311519; ENSP00000307831; ENSG00000173567. ENST00000333478; ENSP00000327396; ENSG00000173567. ENST00000421160; ENSP00000388537; ENSG00000173567. ENST00000447444; ENSP00000404775; ENSG00000173567.
GeneID	165082.
KEGG	hsa:165082.
UCSC	uc002rhe.4. human. uc010eyk.1. human.
Organism-specific databases
CTD	165082.
GeneCards	GC02M026444.
HGNC	HGNC:18989. GPR113.
HPA	HPA044500.
neXtProt	NX_Q8IZF5.
PharmGKB	PA134918027.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG257112.
HOGENOM	HOG000112763.
HOVERGEN	HBG051770.
InParanoid	Q8IZF5.
KO	K08456.
OMA	TIIQDGD.
PhylomeDB	Q8IZF5.
Gene expression databases
ArrayExpress	Q8IZF5.
Bgee	Q8IZF5.
CleanEx	HS_GPR113.
Genevestigator	Q8IZF5.
GermOnline	ENSG00000173567. Homo sapiens.
Family and domain databases
InterPro	IPR022624. DUF3497. IPR017981. GPCR_2-like. IPR001879. GPCR_2_extracellular_dom. IPR000832. GPCR_2_secretin-like. IPR017983. GPCR_2_secretin-like_CS. IPR000203. GPS_dom. [Graphical view]
Pfam	PF00002. 7tm_2. 1 hit. PF12003. DUF3497. 1 hit. PF01825. GPS. 1 hit. PF02793. HRM. 1 hit. [Graphical view]
PRINTS	PR00249. GPCRSECRETIN.
SMART	SM00303. GPS. 1 hit. [Graphical view]
PROSITE	PS00649. G_PROTEIN_RECEP_F2_1. False negative. PS00650. G_PROTEIN_RECEP_F2_2. 1 hit. PS50227. G_PROTEIN_RECEP_F2_3. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. PS50221. GPS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	165082.
NextBio	88517.

Entry information

Entry name

GP113_HUMAN

Accession

Primary (citable) accession number: Q8IZF5
Secondary accession number(s): B4DF15 , E9PEV1, Q53TA5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 96 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.