Q8IZ13 (CE054_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transposon-derived Buster3 transposase-like protein

Gene names

Name:

C5orf54

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	594 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Miscellaneous

May be derived from an ancient transposon that has lost its ability to translocate.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 594	594	Transposon-derived Buster3 transposase-like protein		PRO_0000348452
Natural variations
	Natural variant	523	1	A → S. Corresponds to variant rs10515808 [ dbSNP | Ensembl ].		VAR_046179
Experimental info
	Sequence conflict	63	1	L → F in AAF18452. Ref.1
	Sequence conflict	556	1	T → P in BAB15542. Ref.2
	Sequence conflict	584	1	E → D in BAB15542. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q8IZ13 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: C786B19C80B75263	FASTA	594	68,327
	10 20 30 40 50 60 MSKKRKWDDD YVRYWFTCTT EVDGTQRPQC VLCNSVFSNA DLRPSKLSDH FNRQHGGVAG 70 80 90 100 110 120 HDLNSLKHMP APSDQSETLK AFGVASHEDT LLQASYQFAY LCAKEKNPHT VAEKLVKPCA 130 140 150 160 170 180 LEIAQIVLGP DAQKKLQQVP LSDDVIHSRI DEMSQDILQQ VLEDIKASPL KVGIQLAETT 190 200 210 220 230 240 DMDDCSQLMA FVRYIKEREI VEEFLFCEPL QLSMKGIDVF NLFRDFFLKH KIALDVCGSV 250 260 270 280 290 300 CTDGASSMLG ENSEFVAYVK KEIPHIVVTH CLLNPHALVI KTLPTKLRDA LFTVVRVINF 310 320 330 340 350 360 IKGRAPNHRL FQAFFEEIGI EYSVLLFHTE MRWLSRGQIL THIFEMYEEI NQFLHHKSSN 370 380 390 400 410 420 LVDGFENKEF KIHLAYLADL FKHLNELSAS MQRTGMNTVS AREKLSAFVR KFPFWQKRIE 430 440 450 460 470 480 KRNFTNFPFL EEIIVSDNEG IFIAAEITLH LQQLSNFFHG YFSIGDLNEA SKWILDPFLF 490 500 510 520 530 540 NIDFVDDSYL MKNDLAELRA SGQILMEFET MKLEDFWCAQ FTAFPNLAKT ALEILMPFAT 550 560 570 580 590 TYLCELGFSS LLHFKTKSRS CFNLSDDIRV AISKKVPRFS DIIEQKLQLQ QKSL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Interspersed repeats and other mementos of transposable elements in mammalian genomes." Smit A.F.A. Curr. Opin. Genet. Dev. 9:657-663(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung.
[3]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Leiomyosarcoma and Lung.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF205598 Genomic DNA. Translation: AAF18452.1. AK026754 mRNA. Translation: BAB15542.1. CH471062 Genomic DNA. Translation: EAW61557.1. CH471062 Genomic DNA. Translation: EAW61558.1. CH471062 Genomic DNA. Translation: EAW61559.1. CH471062 Genomic DNA. Translation: EAW61560.1. BC032603 mRNA. Translation: AAH32603.1. BC112128 mRNA. Translation: AAI12129.1. BC112130 mRNA. Translation: AAI12131.1.
IPI	IPI00217843.
RefSeq	NP_071373.2. NM_022090.3.
UniGene	Hs.529464.
3D structure databases
ProteinModelPortal	Q8IZ13.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000386184.
PTM databases
PhosphoSite	Q8IZ13.
Polymorphism databases
DMDM	74728411.
Proteomic databases
PaxDb	Q8IZ13.
PRIDE	Q8IZ13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000408953; ENSP00000386184; ENSG00000221886. ENST00000523213; ENSP00000428831; ENSG00000221886.
GeneID	63920.
KEGG	hsa:63920.
UCSC	uc003lye.1. human.
Organism-specific databases
CTD	63920.
GeneCards	GC05M159752.
HGNC	HGNC:30804. C5orf54.
HPA	HPA045445.
neXtProt	NX_Q8IZ13.
PharmGKB	PA164717348.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG45135.
HOGENOM	HOG000253000.
InParanoid	Q8IZ13.
OMA	EASKWIL.
OrthoDB	EOG4DNF40.
PhylomeDB	Q8IZ13.
Gene expression databases
Bgee	Q8IZ13.
Genevestigator	Q8IZ13.
Family and domain databases
InterPro	IPR026629. Buster3-like. [Graphical view]
PANTHER	PTHR11697:SF2. PTHR11697:SF2. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	C5orf54. human.
GenomeRNAi	63920.
NextBio	65646.

Entry information

Entry name

CE054_HUMAN

Accession

Primary (citable) accession number: Q8IZ13
Secondary accession number(s): D3DQJ9, Q9H5S8, Q9UH87

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.