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Q8IYW2 (CJ092_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C10orf92
Gene names
Name:C10orf92
Synonyms:C10orf123, C10orf124
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length876 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 876876Uncharacterized protein C10orf92
PRO_0000089812

Regions

Compositional bias223 – 2264Poly-Ala
Compositional bias726 – 7294Poly-Ala

Natural variations

Natural variant2861C → R.
Corresponds to variant rs10870341 [ dbSNP | Ensembl ].
VAR_056823
Natural variant4101E → K.
Corresponds to variant rs12356978 [ dbSNP | Ensembl ].
VAR_056824
Natural variant4921A → T. Ref.2 Ref.3
Corresponds to variant rs4880433 [ dbSNP | Ensembl ].
VAR_023208
Natural variant6601L → F.
Corresponds to variant rs3750587 [ dbSNP | Ensembl ].
VAR_056825
Natural variant7011S → G. Ref.2 Ref.3
Corresponds to variant rs2254419 [ dbSNP | Ensembl ].
VAR_023209
Natural variant8191K → Q.
Corresponds to variant rs35981039 [ dbSNP | Ensembl ].
VAR_056826

Sequences

Sequence LengthMass (Da)Tools
Q8IYW2 [UniParc].

Last modified August 16, 2005. Version 2.
Checksum: 54B19CC03F8F2D97

FASTA87695,496
        10         20         30         40         50         60 
MAEEEGRLHS VQGLLSLQDL QNVNTPLMRK LARLKLGLVE MALDMLQFIW EEAHGQQSEQ 

        70         80         90        100        110        120 
GSLEKLLADY LQNTSDYTSV GLQWFTLKRT LAHGALAQLG SLQPLSVGCV EIRARLLGLA 

       130        140        150        160        170        180 
GRALHLLAMQ ADPVHPTCYW EAGPSVGAKL SGLKSLELEV EEEGATKSSR DPPASRAAPE 

       190        200        210        220        230        240 
EHCRRGEDLK RRMVLAQQYL AQASEVLLQC LQVALGSGLL DVAAAASLEM VECVGTLDPA 

       250        260        270        280        290        300 
TTCQFLALSQ SCSASETMRD VLLAATANTS SSQLAALLQL QHQLRCQDRT TTSLGARVEQ 

       310        320        330        340        350        360 
RLAAVSKAWQ NLCVTEQHFN LLNEMPPTFW ILFLHLSGDR SRLYGAAYEK PKFITAAKGK 

       370        380        390        400        410        420 
VQAVGGSCKV MRLAISPTAF SHLLACAQQF RKQTQAQVYS EDMALNIGSE PEGLQVEEKE 

       430        440        450        460        470        480 
RPVQRLSSVL GPLEELLQPL FPLLSLSKAR VQTPAVVADS GKSKGKDKER KTSTGQHSTV 

       490        500        510        520        530        540 
QPEVADKIVL VADRHLLELP LEGLSVFDEG TISSVSREFS LQMLWNRLHK EETEGGVKKE 

       550        560        570        580        590        600 
GRSRDPKKRS LAKKGRKGSI PRTIPPDCII VDSDNFKFVV DPYEEAQGPE MLTPVSITQD 

       610        620        630        640        650        660 
ILERFQDTFT SRWAGHLGSK HFPSQAQWEQ ALGSCSGFFF YGMESFLSHI LVERLVAMNL 

       670        680        690        700        710        720 
QECQVAVLLD LARSYQSLKR HMESVEHRRS VGRWEANWRN SASPSEDEWR RGGEPRRGFS 

       730        740        750        760        770        780 
DLEGQAAAAP KLRAPSHHAQ LGPVWAAAPS HRVVQAWTCL PSAAGAPALA SALGSAPLPT 

       790        800        810        820        830        840 
HPHLPAPIPS SQLALPFLGL SPALGAASAR DPPPATSRKA AAWTSSSACL CAPWGLRRGW 

       850        860        870 
SCVSSRGQDK GGLPLAALVL SCLDQKTIQT VSLFLI

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed: 15164054] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS THR-492 AND GLY-701.
Tissue: Testis.
[3]"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. expand/collapse author list , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A.
Genome Res. 11:422-435(2001) [PubMed: 11230166] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 295-876, VARIANTS THR-492 AND GLY-701.
Tissue: Testis.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL392043 Genomic DNA. Translation: CAI39950.2.
BC034223 mRNA. Translation: AAH34223.1.
AL122111 mRNA. Translation: CAB59272.3.
IPIIPI00217894.
PIRT34538.
RefSeqNP_001186978.1. NM_001200049.1.
UniGeneHs.298038.

3D structure databases

ProteinModelPortalQ8IYW2.
ModBaseSearch...

PTM databases

PhosphoSiteQ8IYW2.

Polymorphism databases

DMDM73620097.

Proteomic databases

PRIDEQ8IYW2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000263170; ENSP00000263170; ENSG00000108046.
GeneID54777.
KEGGhsa:54777.
NMPDRfig|9606.3.peg.4884.
UCSCuc001lls.1. human.

Organism-specific databases

CTD54777.
GeneCardsGC10M134621.
HGNCHGNC:25247. C10orf92.
neXtProtNX_Q8IYW2.
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG05409.
GeneTreeENSGT00570000079216.
InParanoidQ8IYW2.
OMATTCQFLA.
PhylomeDBQ8IYW2.

Gene expression databases

ArrayExpressQ8IYW2.
BgeeQ8IYW2.
CleanExHS_C10orf92.
GenevestigatorQ8IYW2.
GermOnlineENSG00000108046. Homo sapiens.

Family and domain databases

ProtoNetSearch...

Other

NextBio57433.

Entry information

Entry nameCJ092_HUMAN
AccessionPrimary (citable) accession number: Q8IYW2
Secondary accession number(s): Q5JSF7, Q9NTQ5
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: August 16, 2005
Last modified: December 14, 2011
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents