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Protein

Uncharacterized protein C16orf71

Gene

C16orf71

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C16orf71
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:25081. C16orf71.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166246.
PharmGKBiPA145149565.

Polymorphism and mutation databases

BioMutaiC16orf71.
DMDMi296439389.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002943451 – 520Uncharacterized protein C16orf71Add BLAST520

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei161PhosphoserineBy similarity1
Modified residuei351PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8IYS4.
PeptideAtlasiQ8IYS4.
PRIDEiQ8IYS4.

PTM databases

iPTMnetiQ8IYS4.
PhosphoSitePlusiQ8IYS4.

Expressioni

Gene expression databases

BgeeiENSG00000166246.
CleanExiHS_C16orf71.
ExpressionAtlasiQ8IYS4. baseline and differential.
GenevisibleiQ8IYS4. HS.

Organism-specific databases

HPAiHPA049468.

Interactioni

Protein-protein interaction databases

BioGridi126999. 25 interactors.
STRINGi9606.ENSP00000299320.

Structurei

3D structure databases

ProteinModelPortaliQ8IYS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IYMM. Eukaryota.
ENOG4111414. LUCA.
GeneTreeiENSGT00390000015381.
HOGENOMiHOG000070145.
HOVERGENiHBG107749.
InParanoidiQ8IYS4.
PhylomeDBiQ8IYS4.
TreeFamiTF336688.

Family and domain databases

InterProiIPR031531. DUF4701.
[Graphical view]
PfamiPF15773. DUF4701. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IYS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNDKGMAP SLGSPWASQM GPWDAILKAV KDQLPSLDSD SPLSDYGEEE
60 70 80 90 100
LFIFQRNQTS LIPDLSEELA EDPADGDKSR AWVAAAEESL PEPVLVPAEL
110 120 130 140 150
ATEPGCRQNT RTKDASSQEG RDPGRPFESS GEVSALLGMA EEPPRWLEGD
160 170 180 190 200
LGSLSFNTKG SQGPPWDPQA EATLSCHEGD PKAEPLSTAS QESVNRRALR
210 220 230 240 250
QERRKMIETD ILQKVTRDAC GPTSSDKGGV KEAPCHAAES APRSKMPLVE
260 270 280 290 300
PPEGPPVLSL QQLEAWDLDD ILQSLAGQED NQGNRAPGTV WWAADHRQVQ
310 320 330 340 350
DRMVPSAHNR LMEQLALLCT TQSKASACAR KVPADTPQDT KEADSGSRCA
360 370 380 390 400
SRKQGSQAGP GPQLAQGMRL NAESPTIFID LRQMELPDHL SPESSSHSSS
410 420 430 440 450
DSEEEEEEEM AALGDAEGAS PSSLGLRTCT GKSQLLQQLR AFQKGTAQPE
460 470 480 490 500
LPASKGPAGG RAQAPEDTAG SRTGRKQHMK LCAKGQSAQA RLPRGRPRAL
510 520
GDVPEPGAAR EALMPPLEQL
Length:520
Mass (Da):55,682
Last modified:May 18, 2010 - v3
Checksum:i1E160E14948B36E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti19Q → R in AAH35024 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03315788E → D.Corresponds to variant rs17137215dbSNPEnsembl.1
Natural variantiVAR_033158143P → S.Corresponds to variant rs17137230dbSNPEnsembl.1
Natural variantiVAR_033159190S → L.Corresponds to variant rs35599524dbSNPEnsembl.1
Natural variantiVAR_033160232E → K.Corresponds to variant rs35002791dbSNPEnsembl.1
Natural variantiVAR_033161241A → V.Corresponds to variant rs7202010dbSNPEnsembl.1
Natural variantiVAR_033162302R → C.2 PublicationsCorresponds to variant rs2075469dbSNPEnsembl.1
Natural variantiVAR_033163354Q → R.2 PublicationsCorresponds to variant rs737700dbSNPEnsembl.1
Natural variantiVAR_061618465P → L.1 PublicationCorresponds to variant rs17853375dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF447587 mRNA. Translation: AAM22870.1.
AC020663 Genomic DNA. No translation available.
BC035024 mRNA. Translation: AAH35024.1.
CCDSiCCDS10521.1.
RefSeqiNP_631909.2. NM_139170.2.
XP_016878465.1. XM_017022976.1.
UniGeneiHs.602738.

Genome annotation databases

EnsembliENST00000299320; ENSP00000299320; ENSG00000166246.
GeneIDi146562.
KEGGihsa:146562.
UCSCiuc002cxn.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF447587 mRNA. Translation: AAM22870.1.
AC020663 Genomic DNA. No translation available.
BC035024 mRNA. Translation: AAH35024.1.
CCDSiCCDS10521.1.
RefSeqiNP_631909.2. NM_139170.2.
XP_016878465.1. XM_017022976.1.
UniGeneiHs.602738.

3D structure databases

ProteinModelPortaliQ8IYS4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126999. 25 interactors.
STRINGi9606.ENSP00000299320.

PTM databases

iPTMnetiQ8IYS4.
PhosphoSitePlusiQ8IYS4.

Polymorphism and mutation databases

BioMutaiC16orf71.
DMDMi296439389.

Proteomic databases

PaxDbiQ8IYS4.
PeptideAtlasiQ8IYS4.
PRIDEiQ8IYS4.

Protocols and materials databases

DNASUi146562.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000299320; ENSP00000299320; ENSG00000166246.
GeneIDi146562.
KEGGihsa:146562.
UCSCiuc002cxn.4. human.

Organism-specific databases

CTDi146562.
GeneCardsiC16orf71.
HGNCiHGNC:25081. C16orf71.
HPAiHPA049468.
neXtProtiNX_Q8IYS4.
OpenTargetsiENSG00000166246.
PharmGKBiPA145149565.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IYMM. Eukaryota.
ENOG4111414. LUCA.
GeneTreeiENSGT00390000015381.
HOGENOMiHOG000070145.
HOVERGENiHBG107749.
InParanoidiQ8IYS4.
PhylomeDBiQ8IYS4.
TreeFamiTF336688.

Miscellaneous databases

GenomeRNAii146562.
PROiQ8IYS4.

Gene expression databases

BgeeiENSG00000166246.
CleanExiHS_C16orf71.
ExpressionAtlasiQ8IYS4. baseline and differential.
GenevisibleiQ8IYS4. HS.

Family and domain databases

InterProiIPR031531. DUF4701.
[Graphical view]
PfamiPF15773. DUF4701. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCP071_HUMAN
AccessioniPrimary (citable) accession number: Q8IYS4
Secondary accession number(s): Q8NCV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 18, 2010
Last modified: November 2, 2016
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.