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Protein

Uncharacterized protein C16orf71

Gene

C16orf71

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C16orf71
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:25081. C16orf71.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145149565.

Polymorphism and mutation databases

BioMutaiC16orf71.
DMDMi296439389.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520Uncharacterized protein C16orf71PRO_0000294345Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei161 – 1611PhosphoserineBy similarity
Modified residuei351 – 3511PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8IYS4.
PaxDbiQ8IYS4.
PeptideAtlasiQ8IYS4.
PRIDEiQ8IYS4.

PTM databases

iPTMnetiQ8IYS4.
PhosphoSiteiQ8IYS4.

Expressioni

Gene expression databases

BgeeiENSG00000166246.
CleanExiHS_C16orf71.
ExpressionAtlasiQ8IYS4. baseline and differential.
GenevisibleiQ8IYS4. HS.

Organism-specific databases

HPAiHPA049468.

Interactioni

Protein-protein interaction databases

BioGridi126999. 25 interactions.
STRINGi9606.ENSP00000299320.

Structurei

3D structure databases

ProteinModelPortaliQ8IYS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IYMM. Eukaryota.
ENOG4111414. LUCA.
GeneTreeiENSGT00390000015381.
HOGENOMiHOG000070145.
HOVERGENiHBG107749.
InParanoidiQ8IYS4.
PhylomeDBiQ8IYS4.
TreeFamiTF336688.

Family and domain databases

InterProiIPR031531. DUF4701.
[Graphical view]
PfamiPF15773. DUF4701. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IYS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNDKGMAP SLGSPWASQM GPWDAILKAV KDQLPSLDSD SPLSDYGEEE
60 70 80 90 100
LFIFQRNQTS LIPDLSEELA EDPADGDKSR AWVAAAEESL PEPVLVPAEL
110 120 130 140 150
ATEPGCRQNT RTKDASSQEG RDPGRPFESS GEVSALLGMA EEPPRWLEGD
160 170 180 190 200
LGSLSFNTKG SQGPPWDPQA EATLSCHEGD PKAEPLSTAS QESVNRRALR
210 220 230 240 250
QERRKMIETD ILQKVTRDAC GPTSSDKGGV KEAPCHAAES APRSKMPLVE
260 270 280 290 300
PPEGPPVLSL QQLEAWDLDD ILQSLAGQED NQGNRAPGTV WWAADHRQVQ
310 320 330 340 350
DRMVPSAHNR LMEQLALLCT TQSKASACAR KVPADTPQDT KEADSGSRCA
360 370 380 390 400
SRKQGSQAGP GPQLAQGMRL NAESPTIFID LRQMELPDHL SPESSSHSSS
410 420 430 440 450
DSEEEEEEEM AALGDAEGAS PSSLGLRTCT GKSQLLQQLR AFQKGTAQPE
460 470 480 490 500
LPASKGPAGG RAQAPEDTAG SRTGRKQHMK LCAKGQSAQA RLPRGRPRAL
510 520
GDVPEPGAAR EALMPPLEQL
Length:520
Mass (Da):55,682
Last modified:May 18, 2010 - v3
Checksum:i1E160E14948B36E3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti19 – 191Q → R in AAH35024 (PubMed:15489334).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti88 – 881E → D.
Corresponds to variant rs17137215 [ dbSNP | Ensembl ].
VAR_033157
Natural varianti143 – 1431P → S.
Corresponds to variant rs17137230 [ dbSNP | Ensembl ].
VAR_033158
Natural varianti190 – 1901S → L.
Corresponds to variant rs35599524 [ dbSNP | Ensembl ].
VAR_033159
Natural varianti232 – 2321E → K.
Corresponds to variant rs35002791 [ dbSNP | Ensembl ].
VAR_033160
Natural varianti241 – 2411A → V.
Corresponds to variant rs7202010 [ dbSNP | Ensembl ].
VAR_033161
Natural varianti302 – 3021R → C.2 Publications
Corresponds to variant rs2075469 [ dbSNP | Ensembl ].
VAR_033162
Natural varianti354 – 3541Q → R.2 Publications
Corresponds to variant rs737700 [ dbSNP | Ensembl ].
VAR_033163
Natural varianti465 – 4651P → L.1 Publication
Corresponds to variant rs17853375 [ dbSNP | Ensembl ].
VAR_061618

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF447587 mRNA. Translation: AAM22870.1.
AC020663 Genomic DNA. No translation available.
BC035024 mRNA. Translation: AAH35024.1.
CCDSiCCDS10521.1.
RefSeqiNP_631909.2. NM_139170.2.
UniGeneiHs.602738.

Genome annotation databases

EnsembliENST00000299320; ENSP00000299320; ENSG00000166246.
GeneIDi146562.
KEGGihsa:146562.
UCSCiuc002cxn.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF447587 mRNA. Translation: AAM22870.1.
AC020663 Genomic DNA. No translation available.
BC035024 mRNA. Translation: AAH35024.1.
CCDSiCCDS10521.1.
RefSeqiNP_631909.2. NM_139170.2.
UniGeneiHs.602738.

3D structure databases

ProteinModelPortaliQ8IYS4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126999. 25 interactions.
STRINGi9606.ENSP00000299320.

PTM databases

iPTMnetiQ8IYS4.
PhosphoSiteiQ8IYS4.

Polymorphism and mutation databases

BioMutaiC16orf71.
DMDMi296439389.

Proteomic databases

MaxQBiQ8IYS4.
PaxDbiQ8IYS4.
PeptideAtlasiQ8IYS4.
PRIDEiQ8IYS4.

Protocols and materials databases

DNASUi146562.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000299320; ENSP00000299320; ENSG00000166246.
GeneIDi146562.
KEGGihsa:146562.
UCSCiuc002cxn.4. human.

Organism-specific databases

CTDi146562.
GeneCardsiC16orf71.
HGNCiHGNC:25081. C16orf71.
HPAiHPA049468.
neXtProtiNX_Q8IYS4.
PharmGKBiPA145149565.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IYMM. Eukaryota.
ENOG4111414. LUCA.
GeneTreeiENSGT00390000015381.
HOGENOMiHOG000070145.
HOVERGENiHBG107749.
InParanoidiQ8IYS4.
PhylomeDBiQ8IYS4.
TreeFamiTF336688.

Miscellaneous databases

GenomeRNAii146562.
PROiQ8IYS4.

Gene expression databases

BgeeiENSG00000166246.
CleanExiHS_C16orf71.
ExpressionAtlasiQ8IYS4. baseline and differential.
GenevisibleiQ8IYS4. HS.

Family and domain databases

InterProiIPR031531. DUF4701.
[Graphical view]
PfamiPF15773. DUF4701. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCP071_HUMAN
AccessioniPrimary (citable) accession number: Q8IYS4
Secondary accession number(s): Q8NCV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 18, 2010
Last modified: September 7, 2016
This is version 83 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.