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Q8IYN6

- UBAD2_HUMAN

UniProt

Q8IYN6 - UBAD2_HUMAN

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Protein
UBA-like domain-containing protein 2
Gene
UBALD2, FAM100B
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UBA-like domain-containing protein 2
Gene namesi
Name:UBALD2
Synonyms:FAM100B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:28438. UBALD2.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671783.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 164163UBA-like domain-containing protein 2
PRO_0000239028Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ8IYN6.
PRIDEiQ8IYN6.

Expressioni

Gene expression databases

ArrayExpressiQ8IYN6.
BgeeiQ8IYN6.
CleanExiHS_FAM100B.
GenevestigatoriQ8IYN6.

Organism-specific databases

HPAiHPA023046.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000331298.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 2116
Helixi25 – 339
Turni34 – 374
Helixi39 – 479

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DZLNMR-A1-59[»]
ProteinModelPortaliQ8IYN6.
SMRiQ8IYN6. Positions 3-59.

Miscellaneous databases

EvolutionaryTraceiQ8IYN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the UBALD family.

Phylogenomic databases

eggNOGiNOG45670.
HOGENOMiHOG000231197.
HOVERGENiHBG081490.
InParanoidiQ8IYN6.
OMAiHPQPTWP.
OrthoDBiEOG7TMZTR.
PhylomeDBiQ8IYN6.
TreeFamiTF329433.

Family and domain databases

InterProiIPR009060. UBA-like.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8IYN6-1 [UniParc]FASTAAdd to Basket

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MSVNMDELRH QVMINQFVLA AGCAADQAKQ LLQAAHWQFE TALSTFFQET    50
NIPNSHHHHQ MMCTPSNTPA TPPNFPDALA MFSKLRASEG LQSSNSPMTA 100
AACSPPANFS PFWASSPPSH QAPWIPPSSP TTFHHLHRPQ PTWPPGAQQG 150
GAQQKAMAAM DGQR 164
Length:164
Mass (Da):17,877
Last modified:March 1, 2003 - v1
Checksum:i3FF451ADFECBD558
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC035511 mRNA. Translation: AAH35511.1.
BC060859 mRNA. Translation: AAH60859.1.
CCDSiCCDS11742.1.
RefSeqiNP_872371.1. NM_182565.3.
UniGeneiHs.744981.

Genome annotation databases

EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
GeneIDi283991.
KEGGihsa:283991.
UCSCiuc010wsy.1. human.

Polymorphism databases

DMDMi74728359.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC035511 mRNA. Translation: AAH35511.1 .
BC060859 mRNA. Translation: AAH60859.1 .
CCDSi CCDS11742.1.
RefSeqi NP_872371.1. NM_182565.3.
UniGenei Hs.744981.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2DZL NMR - A 1-59 [» ]
ProteinModelPortali Q8IYN6.
SMRi Q8IYN6. Positions 3-59.
ModBasei Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000331298.

Polymorphism databases

DMDMi 74728359.

Proteomic databases

PaxDbi Q8IYN6.
PRIDEi Q8IYN6.

Protocols and materials databases

DNASUi 283991.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000327490 ; ENSP00000331298 ; ENSG00000185262 .
GeneIDi 283991.
KEGGi hsa:283991.
UCSCi uc010wsy.1. human.

Organism-specific databases

CTDi 283991.
GeneCardsi GC17P074262.
HGNCi HGNC:28438. UBALD2.
HPAi HPA023046.
neXtProti NX_Q8IYN6.
PharmGKBi PA142671783.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45670.
HOGENOMi HOG000231197.
HOVERGENi HBG081490.
InParanoidi Q8IYN6.
OMAi HPQPTWP.
OrthoDBi EOG7TMZTR.
PhylomeDBi Q8IYN6.
TreeFami TF329433.

Miscellaneous databases

ChiTaRSi FAM100B. human.
EvolutionaryTracei Q8IYN6.
GenomeRNAii 283991.
NextBioi 94419.
PROi Q8IYN6.

Gene expression databases

ArrayExpressi Q8IYN6.
Bgeei Q8IYN6.
CleanExi HS_FAM100B.
Genevestigatori Q8IYN6.

Family and domain databases

InterProi IPR009060. UBA-like.
[Graphical view ]
SUPFAMi SSF46934. SSF46934. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Placenta.
  2. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
  3. "Solution structure of the UBA domain in human protein FAM100B."
    RIKEN structural genomics initiative (RSGI)
    Submitted (MAR-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 1-59.

Entry informationi

Entry nameiUBAD2_HUMAN
AccessioniPrimary (citable) accession number: Q8IYN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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