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Protein

UBA-like domain-containing protein 2

Gene

UBALD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-31990-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UBA-like domain-containing protein 2
Gene namesi
Name:UBALD2
Synonyms:FAM100B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:28438. UBALD2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185262.
PharmGKBiPA142671783.

Polymorphism and mutation databases

BioMutaiUBALD2.
DMDMi74728359.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002390282 – 164UBA-like domain-containing protein 2Add BLAST163

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ8IYN6.
PeptideAtlasiQ8IYN6.
PRIDEiQ8IYN6.

PTM databases

iPTMnetiQ8IYN6.
PhosphoSitePlusiQ8IYN6.

Expressioni

Gene expression databases

BgeeiENSG00000185262.
CleanExiHS_FAM100B.
ExpressionAtlasiQ8IYN6. baseline and differential.
GenevisibleiQ8IYN6. HS.

Organism-specific databases

HPAiHPA023046.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000331298.

Structurei

Secondary structure

1164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 21Combined sources16
Helixi25 – 33Combined sources9
Turni34 – 37Combined sources4
Helixi39 – 47Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DZLNMR-A1-59[»]
ProteinModelPortaliQ8IYN6.
SMRiQ8IYN6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8IYN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the UBALD family.Curated

Phylogenomic databases

eggNOGiENOG410J092. Eukaryota.
ENOG4111XJX. LUCA.
GeneTreeiENSGT00390000008825.
HOGENOMiHOG000231197.
HOVERGENiHBG081490.
InParanoidiQ8IYN6.
OMAiHQAAWIP.
OrthoDBiEOG091G0ZYA.
PhylomeDBiQ8IYN6.
TreeFamiTF329433.

Family and domain databases

InterProiIPR009060. UBA-like.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8IYN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVNMDELRH QVMINQFVLA AGCAADQAKQ LLQAAHWQFE TALSTFFQET
60 70 80 90 100
NIPNSHHHHQ MMCTPSNTPA TPPNFPDALA MFSKLRASEG LQSSNSPMTA
110 120 130 140 150
AACSPPANFS PFWASSPPSH QAPWIPPSSP TTFHHLHRPQ PTWPPGAQQG
160
GAQQKAMAAM DGQR
Length:164
Mass (Da):17,877
Last modified:March 1, 2003 - v1
Checksum:i3FF451ADFECBD558
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035511 mRNA. Translation: AAH35511.1.
BC060859 mRNA. Translation: AAH60859.1.
CCDSiCCDS11742.1.
RefSeqiNP_872371.1. NM_182565.3.
UniGeneiHs.744981.

Genome annotation databases

EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
GeneIDi283991.
KEGGihsa:283991.
UCSCiuc010wsy.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035511 mRNA. Translation: AAH35511.1.
BC060859 mRNA. Translation: AAH60859.1.
CCDSiCCDS11742.1.
RefSeqiNP_872371.1. NM_182565.3.
UniGeneiHs.744981.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DZLNMR-A1-59[»]
ProteinModelPortaliQ8IYN6.
SMRiQ8IYN6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000331298.

PTM databases

iPTMnetiQ8IYN6.
PhosphoSitePlusiQ8IYN6.

Polymorphism and mutation databases

BioMutaiUBALD2.
DMDMi74728359.

Proteomic databases

PaxDbiQ8IYN6.
PeptideAtlasiQ8IYN6.
PRIDEiQ8IYN6.

Protocols and materials databases

DNASUi283991.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
GeneIDi283991.
KEGGihsa:283991.
UCSCiuc010wsy.2. human.

Organism-specific databases

CTDi283991.
GeneCardsiUBALD2.
HGNCiHGNC:28438. UBALD2.
HPAiHPA023046.
neXtProtiNX_Q8IYN6.
OpenTargetsiENSG00000185262.
PharmGKBiPA142671783.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J092. Eukaryota.
ENOG4111XJX. LUCA.
GeneTreeiENSGT00390000008825.
HOGENOMiHOG000231197.
HOVERGENiHBG081490.
InParanoidiQ8IYN6.
OMAiHQAAWIP.
OrthoDBiEOG091G0ZYA.
PhylomeDBiQ8IYN6.
TreeFamiTF329433.

Enzyme and pathway databases

BioCyciZFISH:G66-31990-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ8IYN6.
GenomeRNAii283991.
PROiQ8IYN6.

Gene expression databases

BgeeiENSG00000185262.
CleanExiHS_FAM100B.
ExpressionAtlasiQ8IYN6. baseline and differential.
GenevisibleiQ8IYN6. HS.

Family and domain databases

InterProiIPR009060. UBA-like.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBAD2_HUMAN
AccessioniPrimary (citable) accession number: Q8IYN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.