Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UBA-like domain-containing protein 2

Gene

UBALD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UBA-like domain-containing protein 2
Gene namesi
Name:UBALD2
Synonyms:FAM100B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:28438. UBALD2.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671783.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 164163UBA-like domain-containing protein 2PRO_0000239028Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ8IYN6.
PRIDEiQ8IYN6.

Expressioni

Gene expression databases

BgeeiQ8IYN6.
CleanExiHS_FAM100B.
ExpressionAtlasiQ8IYN6. baseline and differential.
GenevestigatoriQ8IYN6.

Organism-specific databases

HPAiHPA023046.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000331298.

Structurei

Secondary structure

1
164
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 2116Combined sources
Helixi25 – 339Combined sources
Turni34 – 374Combined sources
Helixi39 – 479Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DZLNMR-A1-59[»]
ProteinModelPortaliQ8IYN6.
SMRiQ8IYN6. Positions 3-59.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8IYN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the UBALD family.Curated

Phylogenomic databases

eggNOGiNOG45670.
GeneTreeiENSGT00390000008825.
HOGENOMiHOG000231197.
HOVERGENiHBG081490.
InParanoidiQ8IYN6.
OMAiHQAAWIP.
OrthoDBiEOG7TMZTR.
PhylomeDBiQ8IYN6.
TreeFamiTF329433.

Family and domain databases

InterProiIPR009060. UBA-like.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8IYN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVNMDELRH QVMINQFVLA AGCAADQAKQ LLQAAHWQFE TALSTFFQET
60 70 80 90 100
NIPNSHHHHQ MMCTPSNTPA TPPNFPDALA MFSKLRASEG LQSSNSPMTA
110 120 130 140 150
AACSPPANFS PFWASSPPSH QAPWIPPSSP TTFHHLHRPQ PTWPPGAQQG
160
GAQQKAMAAM DGQR
Length:164
Mass (Da):17,877
Last modified:March 1, 2003 - v1
Checksum:i3FF451ADFECBD558
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035511 mRNA. Translation: AAH35511.1.
BC060859 mRNA. Translation: AAH60859.1.
CCDSiCCDS11742.1.
RefSeqiNP_872371.1. NM_182565.3.
UniGeneiHs.744981.

Genome annotation databases

EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
GeneIDi283991.
KEGGihsa:283991.
UCSCiuc010wsy.1. human.

Polymorphism databases

DMDMi74728359.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035511 mRNA. Translation: AAH35511.1.
BC060859 mRNA. Translation: AAH60859.1.
CCDSiCCDS11742.1.
RefSeqiNP_872371.1. NM_182565.3.
UniGeneiHs.744981.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DZLNMR-A1-59[»]
ProteinModelPortaliQ8IYN6.
SMRiQ8IYN6. Positions 3-59.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000331298.

Polymorphism databases

DMDMi74728359.

Proteomic databases

PaxDbiQ8IYN6.
PRIDEiQ8IYN6.

Protocols and materials databases

DNASUi283991.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
GeneIDi283991.
KEGGihsa:283991.
UCSCiuc010wsy.1. human.

Organism-specific databases

CTDi283991.
GeneCardsiGC17P074262.
HGNCiHGNC:28438. UBALD2.
HPAiHPA023046.
neXtProtiNX_Q8IYN6.
PharmGKBiPA142671783.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG45670.
GeneTreeiENSGT00390000008825.
HOGENOMiHOG000231197.
HOVERGENiHBG081490.
InParanoidiQ8IYN6.
OMAiHQAAWIP.
OrthoDBiEOG7TMZTR.
PhylomeDBiQ8IYN6.
TreeFamiTF329433.

Miscellaneous databases

EvolutionaryTraceiQ8IYN6.
GenomeRNAii283991.
NextBioi94419.
PROiQ8IYN6.

Gene expression databases

BgeeiQ8IYN6.
CleanExiHS_FAM100B.
ExpressionAtlasiQ8IYN6. baseline and differential.
GenevestigatoriQ8IYN6.

Family and domain databases

InterProiIPR009060. UBA-like.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Placenta.
  2. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
  3. "Solution structure of the UBA domain in human protein FAM100B."
    RIKEN structural genomics initiative (RSGI)
    Submitted (FEB-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 1-59.

Entry informationi

Entry nameiUBAD2_HUMAN
AccessioniPrimary (citable) accession number: Q8IYN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.