Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8IYN6

- UBAD2_HUMAN

UniProt

Q8IYN6 - UBAD2_HUMAN

Protein

UBA-like domain-containing protein 2

Gene

UBALD2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UBA-like domain-containing protein 2
    Gene namesi
    Name:UBALD2
    Synonyms:FAM100B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:28438. UBALD2.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA142671783.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 164163UBA-like domain-containing protein 2PRO_0000239028Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    PaxDbiQ8IYN6.
    PRIDEiQ8IYN6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8IYN6.
    BgeeiQ8IYN6.
    CleanExiHS_FAM100B.
    GenevestigatoriQ8IYN6.

    Organism-specific databases

    HPAiHPA023046.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000331298.

    Structurei

    Secondary structure

    1
    164
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi6 – 2116
    Helixi25 – 339
    Turni34 – 374
    Helixi39 – 479

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2DZLNMR-A1-59[»]
    ProteinModelPortaliQ8IYN6.
    SMRiQ8IYN6. Positions 3-59.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8IYN6.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UBALD family.Curated

    Phylogenomic databases

    eggNOGiNOG45670.
    HOGENOMiHOG000231197.
    HOVERGENiHBG081490.
    InParanoidiQ8IYN6.
    OMAiHPQPTWP.
    OrthoDBiEOG7TMZTR.
    PhylomeDBiQ8IYN6.
    TreeFamiTF329433.

    Family and domain databases

    InterProiIPR009060. UBA-like.
    [Graphical view]
    SUPFAMiSSF46934. SSF46934. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8IYN6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVNMDELRH QVMINQFVLA AGCAADQAKQ LLQAAHWQFE TALSTFFQET    50
    NIPNSHHHHQ MMCTPSNTPA TPPNFPDALA MFSKLRASEG LQSSNSPMTA 100
    AACSPPANFS PFWASSPPSH QAPWIPPSSP TTFHHLHRPQ PTWPPGAQQG 150
    GAQQKAMAAM DGQR 164
    Length:164
    Mass (Da):17,877
    Last modified:March 1, 2003 - v1
    Checksum:i3FF451ADFECBD558
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC035511 mRNA. Translation: AAH35511.1.
    BC060859 mRNA. Translation: AAH60859.1.
    CCDSiCCDS11742.1.
    RefSeqiNP_872371.1. NM_182565.3.
    UniGeneiHs.744981.

    Genome annotation databases

    EnsembliENST00000327490; ENSP00000331298; ENSG00000185262.
    GeneIDi283991.
    KEGGihsa:283991.
    UCSCiuc010wsy.1. human.

    Polymorphism databases

    DMDMi74728359.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC035511 mRNA. Translation: AAH35511.1 .
    BC060859 mRNA. Translation: AAH60859.1 .
    CCDSi CCDS11742.1.
    RefSeqi NP_872371.1. NM_182565.3.
    UniGenei Hs.744981.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2DZL NMR - A 1-59 [» ]
    ProteinModelPortali Q8IYN6.
    SMRi Q8IYN6. Positions 3-59.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000331298.

    Polymorphism databases

    DMDMi 74728359.

    Proteomic databases

    PaxDbi Q8IYN6.
    PRIDEi Q8IYN6.

    Protocols and materials databases

    DNASUi 283991.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000327490 ; ENSP00000331298 ; ENSG00000185262 .
    GeneIDi 283991.
    KEGGi hsa:283991.
    UCSCi uc010wsy.1. human.

    Organism-specific databases

    CTDi 283991.
    GeneCardsi GC17P074262.
    HGNCi HGNC:28438. UBALD2.
    HPAi HPA023046.
    neXtProti NX_Q8IYN6.
    PharmGKBi PA142671783.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45670.
    HOGENOMi HOG000231197.
    HOVERGENi HBG081490.
    InParanoidi Q8IYN6.
    OMAi HPQPTWP.
    OrthoDBi EOG7TMZTR.
    PhylomeDBi Q8IYN6.
    TreeFami TF329433.

    Miscellaneous databases

    ChiTaRSi FAM100B. human.
    EvolutionaryTracei Q8IYN6.
    GenomeRNAii 283991.
    NextBioi 94419.
    PROi Q8IYN6.

    Gene expression databases

    ArrayExpressi Q8IYN6.
    Bgeei Q8IYN6.
    CleanExi HS_FAM100B.
    Genevestigatori Q8IYN6.

    Family and domain databases

    InterProi IPR009060. UBA-like.
    [Graphical view ]
    SUPFAMi SSF46934. SSF46934. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain and Placenta.
    2. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
    3. "Solution structure of the UBA domain in human protein FAM100B."
      RIKEN structural genomics initiative (RSGI)
      Submitted (MAR-2007) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 1-59.

    Entry informationi

    Entry nameiUBAD2_HUMAN
    AccessioniPrimary (citable) accession number: Q8IYN6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3