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Q8IYN3

- Q8IYN3_HUMAN

UniProt

Q8IYN3 - Q8IYN3_HUMAN

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Protein
Submitted name: HMHA1 protein
Gene
HMHA1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
HMHA1 proteinImported
Gene namesi
Name:HMHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8IYN3.

Structurei

3D structure databases

ProteinModelPortaliQ8IYN3.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG107979.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR001060. FCH_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8IYN3-1 [UniParc]FASTAAdd to Basket

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PRVRPYRAGR QGPQQRGRDP GIQLTELPRK DGADAVFPGP SLEPPAGSSG     50
VKATGTLKRP TSLSRHASAA GFPLSGAASW TLGRSHRSPL TAASPGELPT 100
EGAGPDVVED ISHLLADVAR FAEGLEKLKE CVLRDDLLEA RRPRAHECLG 150
EALRVMHQII SKYPLLNTVE TLTAAGTLIA KVKAFHYESN NDLEKQEFEK 200
ALETIAVAFS STVSEFLMGE VDSSTLLAVP PGDSSQSMES LYGPGSEGTP 250
PSLDDCDAGC LPAEEVDVLL QRSEGGVDAA LLYAKNMAKY MKDLISYLEK 300
RTTLEMEFAK GLQKIAHNCR QSVMQEPHMP LLSIYSLALE QDLEFGHSMV 350
QAVGTLQTQT FMQPLTLRRL EHEKRRKEIK EAWHRAQRKL QEAESNLRKA 400
KQGYVQRCED HDKARFLVAK AEEEQAGSAP GAGGTATKTL DKRRRLEEEA 450
KNKAEEAMAT YRTCVADAKT QKQELEDTKV TALRQIQEVI RQSDQTIKSA 500
TISYYQMMHM QTAPLPVHFQ MLCESSKLYD PGQQYASHVR QLQRDQEPDV 550
HYDFEPHVSA NAWSPVMRAR KSSFNVSDVA RPEAAGSPPE EGGCTEGTPA 600
KDHRAGRGHQ VHKSWPLSIS DSDSGLDPGP GAGDFKKFER TSSSGTMSST 650
EELVDPDGGA GASAFEQADL NGMTPELPVA VPSGPFRHEG LSKAARTHRL 700
RKLRTPAKCR ECNSYVYFQG AECEECCLAC HKKCLETLAI QCGHKKLQGR 750
LQLFGQDFSH AARSAPDGVP FIVKKCVCEI ERRALRTKGI YRVNGVKTRV 800
EKLCQAFENG KELVELSQAS PHDISNVLKL YLRQLPEPLI SFRLYHELVG 850
LAKDSLKAEA EAKAASRGRQ DGSESEAVAV ALAGRLRELL RDLPPENRAS 900
LQYLLRHLRR IVEVEQDNKM TPGNLGIVFG PTLLRPRPTE ATVSLSSLVD 950
YPHQARVIET LIVHYGLVFE EEPEETPGGQ DESSNQRAEV VVQVPYLEAG 1000
EAVVYPLQEA AADGCRESRV VSNDSDSDLE EASELLSSSE ASALGHLSFL 1050
EQQQSEASLE VASGSHSGSE EQLEATARED GDGDEDGPAQ QLSGFNTNQS 1100
NNVLQAPLPP MRLRGGRMTL GSCRERQPEF V 1131
Length:1,131
Mass (Da):124,083
Last modified:March 1, 2003 - v1
Checksum:iA606B1AA52014925
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC035564 mRNA. Translation: AAH35564.1.
UniGeneiHs.465521.
Hs.710732.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC035564 mRNA. Translation: AAH35564.1 .
UniGenei Hs.465521.
Hs.710732.

3D structure databases

ProteinModelPortali Q8IYN3.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8IYN3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG107979.

Miscellaneous databases

ChiTaRSi HMHA1. human.

Family and domain databases

Gene3Di 1.10.555.10. 1 hit.
InterProi IPR001060. FCH_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view ]
Pfami PF00620. RhoGAP. 1 hit.
[Graphical view ]
SMARTi SM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view ]
SUPFAMi SSF48350. SSF48350. 1 hit.
PROSITEi PS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: CervixImported.

Entry informationi

Entry nameiQ8IYN3_HUMAN
AccessioniPrimary (citable) accession number: Q8IYN3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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