Q8IYN3 (Q8IYN3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
HMHA1 protein EMBL AAH35564.1

Gene names

Name:

HMHA1 EMBL AAH35564.1

Organism

Homo sapiens (Human) EMBL AAH35564.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1131 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	Metal-binding SAAS SAAS002219 Zinc SAAS SAAS002219
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH35564.1

Sequences

	Sequence		Length	Mass (Da)
	Q8IYN3 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: A606B1AA52014925	FASTA	1,131	124,083
	10 20 30 40 50 60 PRVRPYRAGR QGPQQRGRDP GIQLTELPRK DGADAVFPGP SLEPPAGSSG VKATGTLKRP 70 80 90 100 110 120 TSLSRHASAA GFPLSGAASW TLGRSHRSPL TAASPGELPT EGAGPDVVED ISHLLADVAR 130 140 150 160 170 180 FAEGLEKLKE CVLRDDLLEA RRPRAHECLG EALRVMHQII SKYPLLNTVE TLTAAGTLIA 190 200 210 220 230 240 KVKAFHYESN NDLEKQEFEK ALETIAVAFS STVSEFLMGE VDSSTLLAVP PGDSSQSMES 250 260 270 280 290 300 LYGPGSEGTP PSLDDCDAGC LPAEEVDVLL QRSEGGVDAA LLYAKNMAKY MKDLISYLEK 310 320 330 340 350 360 RTTLEMEFAK GLQKIAHNCR QSVMQEPHMP LLSIYSLALE QDLEFGHSMV QAVGTLQTQT 370 380 390 400 410 420 FMQPLTLRRL EHEKRRKEIK EAWHRAQRKL QEAESNLRKA KQGYVQRCED HDKARFLVAK 430 440 450 460 470 480 AEEEQAGSAP GAGGTATKTL DKRRRLEEEA KNKAEEAMAT YRTCVADAKT QKQELEDTKV 490 500 510 520 530 540 TALRQIQEVI RQSDQTIKSA TISYYQMMHM QTAPLPVHFQ MLCESSKLYD PGQQYASHVR 550 560 570 580 590 600 QLQRDQEPDV HYDFEPHVSA NAWSPVMRAR KSSFNVSDVA RPEAAGSPPE EGGCTEGTPA 610 620 630 640 650 660 KDHRAGRGHQ VHKSWPLSIS DSDSGLDPGP GAGDFKKFER TSSSGTMSST EELVDPDGGA 670 680 690 700 710 720 GASAFEQADL NGMTPELPVA VPSGPFRHEG LSKAARTHRL RKLRTPAKCR ECNSYVYFQG 730 740 750 760 770 780 AECEECCLAC HKKCLETLAI QCGHKKLQGR LQLFGQDFSH AARSAPDGVP FIVKKCVCEI 790 800 810 820 830 840 ERRALRTKGI YRVNGVKTRV EKLCQAFENG KELVELSQAS PHDISNVLKL YLRQLPEPLI 850 860 870 880 890 900 SFRLYHELVG LAKDSLKAEA EAKAASRGRQ DGSESEAVAV ALAGRLRELL RDLPPENRAS 910 920 930 940 950 960 LQYLLRHLRR IVEVEQDNKM TPGNLGIVFG PTLLRPRPTE ATVSLSSLVD YPHQARVIET 970 980 990 1000 1010 1020 LIVHYGLVFE EEPEETPGGQ DESSNQRAEV VVQVPYLEAG EAVVYPLQEA AADGCRESRV 1030 1040 1050 1060 1070 1080 VSNDSDSDLE EASELLSSSE ASALGHLSFL EQQQSEASLE VASGSHSGSE EQLEATARED 1090 1100 1110 1120 1130 GDGDEDGPAQ QLSGFNTNQS NNVLQAPLPP MRLRGGRMTL GSCRERQPEF V

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Cervix EMBL AAH35564.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC035564 mRNA. Translation: AAH35564.1.
IPI	IPI01015186.
UniGene	Hs.465521.
3D structure databases
HSSP	HSSP built from PDB template 1F7C based on UniProtKB Q98935.
ProteinModelPortal	Q8IYN3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG107979.
Family and domain databases
Gene3D	1.10.555.10. 1 hit.
InterPro	IPR001060. FCH_dom. IPR002219. Prot_Kinase_C-like_PE/DAG-bd. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. [Graphical view]
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00109. C1. 1 hit. SM00055. FCH. 1 hit. SM00324. RhoGAP. 1 hit. [Graphical view]
SUPFAM	SSF48350. Rho_GAP. 1 hit.
PROSITE	PS50238. RHOGAP. 1 hit. PS00479. ZF_DAG_PE_1. 1 hit. PS50081. ZF_DAG_PE_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	HMHA1. human.

Entry information

Entry name

Q8IYN3_HUMAN

Accession

Primary (citable) accession number: Q8IYN3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.