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Q8IYN3 (Q8IYN3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:HMHA1 EMBL AAH35564.1
OrganismHomo sapiens (Human) EMBL AAH35564.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1131 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processintracellular signal transduction

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH35564.1

Sequences

Sequence LengthMass (Da)Tools
Q8IYN3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: A606B1AA52014925

FASTA1,131124,083
        10         20         30         40         50         60 
PRVRPYRAGR QGPQQRGRDP GIQLTELPRK DGADAVFPGP SLEPPAGSSG VKATGTLKRP 

        70         80         90        100        110        120 
TSLSRHASAA GFPLSGAASW TLGRSHRSPL TAASPGELPT EGAGPDVVED ISHLLADVAR 

       130        140        150        160        170        180 
FAEGLEKLKE CVLRDDLLEA RRPRAHECLG EALRVMHQII SKYPLLNTVE TLTAAGTLIA 

       190        200        210        220        230        240 
KVKAFHYESN NDLEKQEFEK ALETIAVAFS STVSEFLMGE VDSSTLLAVP PGDSSQSMES 

       250        260        270        280        290        300 
LYGPGSEGTP PSLDDCDAGC LPAEEVDVLL QRSEGGVDAA LLYAKNMAKY MKDLISYLEK 

       310        320        330        340        350        360 
RTTLEMEFAK GLQKIAHNCR QSVMQEPHMP LLSIYSLALE QDLEFGHSMV QAVGTLQTQT 

       370        380        390        400        410        420 
FMQPLTLRRL EHEKRRKEIK EAWHRAQRKL QEAESNLRKA KQGYVQRCED HDKARFLVAK 

       430        440        450        460        470        480 
AEEEQAGSAP GAGGTATKTL DKRRRLEEEA KNKAEEAMAT YRTCVADAKT QKQELEDTKV 

       490        500        510        520        530        540 
TALRQIQEVI RQSDQTIKSA TISYYQMMHM QTAPLPVHFQ MLCESSKLYD PGQQYASHVR 

       550        560        570        580        590        600 
QLQRDQEPDV HYDFEPHVSA NAWSPVMRAR KSSFNVSDVA RPEAAGSPPE EGGCTEGTPA 

       610        620        630        640        650        660 
KDHRAGRGHQ VHKSWPLSIS DSDSGLDPGP GAGDFKKFER TSSSGTMSST EELVDPDGGA 

       670        680        690        700        710        720 
GASAFEQADL NGMTPELPVA VPSGPFRHEG LSKAARTHRL RKLRTPAKCR ECNSYVYFQG 

       730        740        750        760        770        780 
AECEECCLAC HKKCLETLAI QCGHKKLQGR LQLFGQDFSH AARSAPDGVP FIVKKCVCEI 

       790        800        810        820        830        840 
ERRALRTKGI YRVNGVKTRV EKLCQAFENG KELVELSQAS PHDISNVLKL YLRQLPEPLI 

       850        860        870        880        890        900 
SFRLYHELVG LAKDSLKAEA EAKAASRGRQ DGSESEAVAV ALAGRLRELL RDLPPENRAS 

       910        920        930        940        950        960 
LQYLLRHLRR IVEVEQDNKM TPGNLGIVFG PTLLRPRPTE ATVSLSSLVD YPHQARVIET 

       970        980        990       1000       1010       1020 
LIVHYGLVFE EEPEETPGGQ DESSNQRAEV VVQVPYLEAG EAVVYPLQEA AADGCRESRV 

      1030       1040       1050       1060       1070       1080 
VSNDSDSDLE EASELLSSSE ASALGHLSFL EQQQSEASLE VASGSHSGSE EQLEATARED 

      1090       1100       1110       1120       1130 
GDGDEDGPAQ QLSGFNTNQS NNVLQAPLPP MRLRGGRMTL GSCRERQPEF V 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Cervix EMBL AAH35564.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC035564 mRNA. Translation: AAH35564.1.
UniGeneHs.465521.
Hs.710732.

3D structure databases

ProteinModelPortalQ8IYN3.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ8IYN3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG107979.

Family and domain databases

Gene3D1.10.555.10. 1 hit.
InterProIPR001060. FCH_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTSM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMSSF48350. SSF48350. 1 hit.
PROSITEPS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHMHA1. human.

Entry information

Entry nameQ8IYN3_HUMAN
AccessionPrimary (citable) accession number: Q8IYN3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.