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Q8IYN3

- Q8IYN3_HUMAN

UniProt

Q8IYN3 - Q8IYN3_HUMAN

Protein
Submitted name:

HMHA1 protein

Gene

HMHA1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    HMHA1 proteinImported
    Gene namesi
    Name:HMHA1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8IYN3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IYN3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG107979.

    Family and domain databases

    Gene3Di1.10.555.10. 1 hit.
    InterProiIPR001060. FCH_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR008936. Rho_GTPase_activation_prot.
    IPR000198. RhoGAP_dom.
    [Graphical view]
    PfamiPF00620. RhoGAP. 1 hit.
    [Graphical view]
    SMARTiSM00109. C1. 1 hit.
    SM00055. FCH. 1 hit.
    SM00324. RhoGAP. 1 hit.
    [Graphical view]
    SUPFAMiSSF48350. SSF48350. 1 hit.
    PROSITEiPS50238. RHOGAP. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8IYN3-1 [UniParc]FASTAAdd to Basket

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    PRVRPYRAGR QGPQQRGRDP GIQLTELPRK DGADAVFPGP SLEPPAGSSG     50
    VKATGTLKRP TSLSRHASAA GFPLSGAASW TLGRSHRSPL TAASPGELPT 100
    EGAGPDVVED ISHLLADVAR FAEGLEKLKE CVLRDDLLEA RRPRAHECLG 150
    EALRVMHQII SKYPLLNTVE TLTAAGTLIA KVKAFHYESN NDLEKQEFEK 200
    ALETIAVAFS STVSEFLMGE VDSSTLLAVP PGDSSQSMES LYGPGSEGTP 250
    PSLDDCDAGC LPAEEVDVLL QRSEGGVDAA LLYAKNMAKY MKDLISYLEK 300
    RTTLEMEFAK GLQKIAHNCR QSVMQEPHMP LLSIYSLALE QDLEFGHSMV 350
    QAVGTLQTQT FMQPLTLRRL EHEKRRKEIK EAWHRAQRKL QEAESNLRKA 400
    KQGYVQRCED HDKARFLVAK AEEEQAGSAP GAGGTATKTL DKRRRLEEEA 450
    KNKAEEAMAT YRTCVADAKT QKQELEDTKV TALRQIQEVI RQSDQTIKSA 500
    TISYYQMMHM QTAPLPVHFQ MLCESSKLYD PGQQYASHVR QLQRDQEPDV 550
    HYDFEPHVSA NAWSPVMRAR KSSFNVSDVA RPEAAGSPPE EGGCTEGTPA 600
    KDHRAGRGHQ VHKSWPLSIS DSDSGLDPGP GAGDFKKFER TSSSGTMSST 650
    EELVDPDGGA GASAFEQADL NGMTPELPVA VPSGPFRHEG LSKAARTHRL 700
    RKLRTPAKCR ECNSYVYFQG AECEECCLAC HKKCLETLAI QCGHKKLQGR 750
    LQLFGQDFSH AARSAPDGVP FIVKKCVCEI ERRALRTKGI YRVNGVKTRV 800
    EKLCQAFENG KELVELSQAS PHDISNVLKL YLRQLPEPLI SFRLYHELVG 850
    LAKDSLKAEA EAKAASRGRQ DGSESEAVAV ALAGRLRELL RDLPPENRAS 900
    LQYLLRHLRR IVEVEQDNKM TPGNLGIVFG PTLLRPRPTE ATVSLSSLVD 950
    YPHQARVIET LIVHYGLVFE EEPEETPGGQ DESSNQRAEV VVQVPYLEAG 1000
    EAVVYPLQEA AADGCRESRV VSNDSDSDLE EASELLSSSE ASALGHLSFL 1050
    EQQQSEASLE VASGSHSGSE EQLEATARED GDGDEDGPAQ QLSGFNTNQS 1100
    NNVLQAPLPP MRLRGGRMTL GSCRERQPEF V 1131
    Length:1,131
    Mass (Da):124,083
    Last modified:March 1, 2003 - v1
    Checksum:iA606B1AA52014925
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC035564 mRNA. Translation: AAH35564.1.
    UniGeneiHs.465521.
    Hs.710732.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC035564 mRNA. Translation: AAH35564.1 .
    UniGenei Hs.465521.
    Hs.710732.

    3D structure databases

    ProteinModelPortali Q8IYN3.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8IYN3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG107979.

    Miscellaneous databases

    ChiTaRSi HMHA1. human.

    Family and domain databases

    Gene3Di 1.10.555.10. 1 hit.
    InterProi IPR001060. FCH_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR008936. Rho_GTPase_activation_prot.
    IPR000198. RhoGAP_dom.
    [Graphical view ]
    Pfami PF00620. RhoGAP. 1 hit.
    [Graphical view ]
    SMARTi SM00109. C1. 1 hit.
    SM00055. FCH. 1 hit.
    SM00324. RhoGAP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48350. SSF48350. 1 hit.
    PROSITEi PS50238. RHOGAP. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: CervixImported.

    Entry informationi

    Entry nameiQ8IYN3_HUMAN
    AccessioniPrimary (citable) accession number: Q8IYN3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.