Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transcription elongation factor A protein-like 8

Gene

TCEAL8

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May be involved in transcriptional regulation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription elongation factor A protein-like 8
Short name:
TCEA-like protein 8
Alternative name(s):
Transcription elongation factor S-II protein-like 8
Gene namesi
Name:TCEAL8
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000180964.16
HGNCiHGNC:28683 TCEAL8
neXtProtiNX_Q8IYN2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000180964
PharmGKBiPA134991274

Polymorphism and mutation databases

BioMutaiTCEAL8
DMDMi74762496

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002392161 – 117Transcription elongation factor A protein-like 8Add BLAST117

Proteomic databases

EPDiQ8IYN2
MaxQBiQ8IYN2
PaxDbiQ8IYN2
PeptideAtlasiQ8IYN2
PRIDEiQ8IYN2

PTM databases

iPTMnetiQ8IYN2
PhosphoSitePlusiQ8IYN2

Expressioni

Gene expression databases

BgeeiENSG00000180964
CleanExiHS_TCEAL8
ExpressionAtlasiQ8IYN2 baseline and differential
GenevisibleiQ8IYN2 HS

Organism-specific databases

HPAiHPA059115

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi124770, 5 interactors
IntActiQ8IYN2, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8IYN2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili73 – 100Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the TFS-II family. TFA subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JBTZ Eukaryota
ENOG4111DNR LUCA
GeneTreeiENSGT00730000111091
HOGENOMiHOG000231343
HOVERGENiHBG098559
InParanoidiQ8IYN2
OMAiSCDENEG
OrthoDBiEOG091G13IU
PhylomeDBiQ8IYN2
TreeFamiTF336871

Family and domain databases

InterProiView protein in InterPro
IPR021156 TF_A-like/BEX
PfamiView protein in Pfam
PF04538 BEX, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IYN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKSCEENEG KPQNMPKAEE DRPLEDVPQE AEGNPQPSEE GVSQEAEGNP
60 70 80 90 100
RGGPNQPGQG FKEDTPVRHL DPEEMIRGVD ELERLREEIR RVRNKFVMMH
110
WKQRHSRSRP YPVCFRP
Length:117
Mass (Da):13,616
Last modified:March 1, 2003 - v1
Checksum:i8BCFC0CAC699C7A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035573 mRNA Translation: AAH35573.1
Z68694 Genomic DNA No translation available.
CCDSiCCDS14504.1
RefSeqiNP_001006685.1, NM_001006684.1
NP_699164.1, NM_153333.2
UniGeneiHs.389734

Genome annotation databases

EnsembliENST00000360000; ENSP00000353093; ENSG00000180964
ENST00000372685; ENSP00000361770; ENSG00000180964
GeneIDi90843
KEGGihsa:90843
UCSCiuc004ejx.4 human

Similar proteinsi

Entry informationi

Entry nameiTCAL8_HUMAN
AccessioniPrimary (citable) accession number: Q8IYN2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health