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Protein

Uncharacterized protein C20orf196

Gene

C20orf196

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C20orf196
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000171984.14.
HGNCiHGNC:26318. C20orf196.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171984.
PharmGKBiPA145149476.

Polymorphism and mutation databases

BioMutaiC20orf196.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002866121 – 205Uncharacterized protein C20orf196Add BLAST205

Proteomic databases

PaxDbiQ8IYI0.
PRIDEiQ8IYI0.

PTM databases

iPTMnetiQ8IYI0.
PhosphoSitePlusiQ8IYI0.

Expressioni

Gene expression databases

BgeeiENSG00000171984.
CleanExiHS_C20orf196.
ExpressionAtlasiQ8IYI0. baseline and differential.
GenevisibleiQ8IYI0. HS.

Organism-specific databases

HPAiHPA040749.

Interactioni

Protein-protein interaction databases

BioGridi127244. 3 interactors.
IntActiQ8IYI0. 3 interactors.
MINTiMINT-8417631.
STRINGi9606.ENSP00000305875.

Structurei

3D structure databases

ProteinModelPortaliQ8IYI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IVHP. Eukaryota.
ENOG411156Z. LUCA.
GeneTreeiENSGT00390000014969.
HOGENOMiHOG000013194.
HOVERGENiHBG096587.
InParanoidiQ8IYI0.
OMAiQCLSQKI.
OrthoDBiEOG091G0J83.
PhylomeDBiQ8IYI0.
TreeFamiTF336046.

Family and domain databases

InterProiView protein in InterPro
IPR027821. DUF4521.
PANTHERiPTHR36863. PTHR36863. 1 hit.
PfamiView protein in Pfam
PF15021. DUF4521. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8IYI0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAARDATSGS LSEESSALDL PSACDIRDYV LQGPSQEANS EAFSSLEFHS
60 70 80 90 100
FPYSSDVDPD TSNLNIEQNN SWTAENFWLD PAVKGQSEKE EDDGLRKSLD
110 120 130 140 150
RFYEMFGHPQ PGSANSLSAS VCKCLSQKIT QLRGQESQKY ALRSFQMARV
160 170 180 190 200
IFNRDGCSVL QRHSRDTHFY PLEEGSTSLD DEKPNPGLSK DITHFLLQQN

VMKDL
Length:205
Mass (Da):22,938
Last modified:March 1, 2003 - v1
Checksum:i4AF85DA351FF5FAF
GO
Isoform 2 (identifier: Q8IYI0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     142-195: Missing.

Show »
Length:151
Mass (Da):16,706
Checksum:i48EE73BEA8B6F3E0
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03214423A → V. Corresponds to variant dbSNP:rs237422Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_025125142 – 195Missing in isoform 2. 1 PublicationAdd BLAST54

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057796 mRNA. Translation: BAB71578.1.
AK292708 mRNA. Translation: BAF85397.1.
AL390028, AL035249 Genomic DNA. Translation: CAI22784.1.
AL390028, AL035249 Genomic DNA. Translation: CAI22786.1.
AL035249, AL390028 Genomic DNA. Translation: CAI19011.1.
AL035249, AL390028 Genomic DNA. Translation: CAI19013.1.
CH471133 Genomic DNA. Translation: EAX10412.1.
BC035800 mRNA. Translation: AAH35800.1.
CCDSiCCDS13091.1. [Q8IYI0-1]
RefSeqiNP_001290406.1. NM_001303477.1. [Q8IYI0-1]
NP_001290407.1. NM_001303478.1.
NP_001290408.1. NM_001303479.1.
NP_689717.2. NM_152504.3. [Q8IYI0-1]
XP_016883173.1. XM_017027684.1. [Q8IYI0-1]
UniGeneiHs.529340.

Genome annotation databases

EnsembliENST00000303142; ENSP00000305875; ENSG00000171984. [Q8IYI0-1]
GeneIDi149840.
KEGGihsa:149840.
UCSCiuc002wmf.4. human. [Q8IYI0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCT196_HUMAN
AccessioniPrimary (citable) accession number: Q8IYI0
Secondary accession number(s): A8K9J3, Q5TGA9, Q96LU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations