SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8IYB4

- PEX5R_HUMAN

UniProt

Q8IYB4 - PEX5R_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
PEX5-related protein
Gene
PEX5L, PEX5R, PXR2
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence By similarity.

GO - Molecular functioni

  1. peroxisome matrix targeting signal-1 binding Source: RefGenome
  2. peroxisome targeting sequence binding Source: UniProtKB
  3. small GTPase binding Source: UniProtKB

GO - Biological processi

  1. maintenance of protein location Source: Ensembl
  2. protein import into peroxisome matrix Source: RefGenome
  3. protein import into peroxisome matrix, docking Source: RefGenome
  4. regulation of cAMP-mediated signaling Source: UniProtKB
  5. regulation of membrane potential Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
PEX5-related protein
Alternative name(s):
PEX2-related protein
PEX5-like protein
Peroxin-5-related protein
Peroxisome biogenesis factor 5-like
Tetratricopeptide repeat-containing Rab8b-interacting protein
Short name:
Pex5Rp
Short name:
TRIP8b
Gene namesi
Name:PEX5L
Synonyms:PEX5R, PXR2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:30024. PEX5L.

Subcellular locationi

Cytoplasm By similarity. Membrane; Peripheral membrane protein By similarity
Note: Some fraction is membrane associated via its interaction with RAB8B By similarity.1 Publication

GO - Cellular componenti

  1. cytosol Source: RefGenome
  2. dendrite Source: Ensembl
  3. peroxisomal membrane Source: RefGenome
  4. receptor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134892044.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 626626PEX5-related protein
PRO_0000106317Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei261 – 2611Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8IYB4.
PRIDEiQ8IYB4.

PTM databases

PhosphoSiteiQ8IYB4.

Expressioni

Tissue specificityi

Mainly expressed in brain. Also expressed in pancreas, testis and pituitary.1 Publication

Gene expression databases

ArrayExpressiQ8IYB4.
BgeeiQ8IYB4.
CleanExiHS_PEX5L.
GenevestigatoriQ8IYB4.

Organism-specific databases

HPAiHPA040216.

Interactioni

Subunit structurei

Interacts with RAB8B. Forms an obligate 4:4 complex with HCN2 By similarity. May interact with the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type); the relevance of such interaction is however unclear.1 Publication

Protein-protein interaction databases

BioGridi119607. 1 interaction.
DIPiDIP-58547N.
STRINGi9606.ENSP00000419975.

Structurei

3D structure databases

ProteinModelPortaliQ8IYB4.
SMRiQ8IYB4. Positions 314-625.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati326 – 35934TPR 1
Add
BLAST
Repeati360 – 39334TPR 2
Add
BLAST
Repeati395 – 42733TPR 3
Add
BLAST
Repeati474 – 50734TPR 4
Add
BLAST
Repeati509 – 54133TPR 5
Add
BLAST
Repeati543 – 57533TPR 6
Add
BLAST

Sequence similaritiesi

Contains 6 TPR repeats.

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiCOG0457.
HOGENOMiHOG000158146.
HOVERGENiHBG053575.
InParanoidiQ8IYB4.
OMAiQPLRGPE.
OrthoDBiEOG793B77.
PhylomeDBiQ8IYB4.
TreeFamiTF315044.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR024112. PEX5-rel.
IPR024111. PTS1R_family.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR10130. PTHR10130. 1 hit.
PTHR10130:SF1. PTHR10130:SF1. 1 hit.
PfamiPF00515. TPR_1. 2 hits.
[Graphical view]
SMARTiSM00028. TPR. 5 hits.
[Graphical view]
PROSITEiPS50005. TPR. 5 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequences (8)i

Sequence statusi: Complete.

This entry describes 8 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8IYB4-1) [UniParc]FASTAAdd to Basket

Also known as: PXR2b

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MYQGHMQKSK EQGYGKLSSD EDLEIIVDQK QGKGSRAADK AVAMVMKEIP    50
REESAEEKPL LTMTSQLVNE QQESRPLLSP SIDDFLCETK SEAIARPVTS 100
NTAVLTTGLD LLDLSEPVSQ TQTKAKKSEP SSKTSSLKKK ADGSDLISTD 150
AEQRGQPLRV PETSSLDLDI QTQLEKWDDV KFHGDRNTKG HPMAERKSSS 200
SRTGSKELLW SSEHRSQPEL SGGKSALNSE SASELELVAP TQARLTKEHR 250
WGSALLSRNH SLEEEFERAK AAVESDTEFW DKMQAEWEEM ARRNWISENQ 300
EAQNQVTISA SEKGYYFHTE NPFKDWPGAF EEGLKRLKEG DLPVTILFME 350
AAILQDPGDA EAWQFLGITQ AENENEQAAI VALQRCLELQ PNNLKALMAL 400
AVSYTNTGHQ QDACDALKNW IKQNPKYKYL VKSKKGSPGL TRRMSKSPVD 450
SSVLEGVKEL YLEAAHQNGD MIDPDLQTGL GVLFHLSGEF NRAIDAFNAA 500
LTVRPEDYSL WNRLGATLAN GDRSEEAVEA YTRALEIQPG FIRSRYNLGI 550
SCINLGAYRE AVSNFLTALS LQRKSRNQQQ VPHPAISGNI WAALRIALSL 600
MDQPELFQAA NLGDLDVLLR AFNLDP 626
Length:626
Mass (Da):69,697
Last modified:May 24, 2004 - v2
Checksum:i07109ABE1B2314C1
GO
Isoform 2 (identifier: Q8IYB4-2) [UniParc]FASTAAdd to Basket

Also known as: PXR2a

The sequence of this isoform differs from the canonical sequence as follows:
     8-31: KSKEQGYGKLSSDEDLEIIVDQKQ → VVGVTLKKKWHCLQKSDLTLAL

Show »
Length:624
Mass (Da):69,440
Checksum:i1DDBBDDC6F190235
GO
Isoform 3 (identifier: Q8IYB4-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     32-66: Missing.

Show »
Length:591
Mass (Da):65,925
Checksum:i62176C47BB9C5C21
GO
Isoform 4 (identifier: Q8IYB4-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     7-65: Missing.

Note: No experimental confirmation available.

Show »
Length:567
Mass (Da):63,205
Checksum:iDB22E2E2FE2BC3F9
GO
Isoform 5 (identifier: Q8IYB4-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-43: Missing.

Show »
Length:583
Mass (Da):64,989
Checksum:iBA1CD881FACB3C60
GO
Isoform 6 (identifier: Q8IYB4-6) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     7-30: Missing.

Show »
Length:602
Mass (Da):66,977
Checksum:i167497DDAC5F36B4
GO
Isoform 7 (identifier: Q8IYB4-7) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-43: Missing.
     104-168: Missing.

Show »
Length:518
Mass (Da):58,079
Checksum:iD27BA80B03F9F914
GO
Isoform 8 (identifier: Q8IYB4-8) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-192: Missing.

Show »
Length:434
Mass (Da):48,529
Checksum:i510C8912004FB8F9
GO

Sequence cautioni

The sequence CAC01120.1 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti226 – 2261A → T in a colorectal cancer sample; somatic mutation. 1 Publication
VAR_035865

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 192192Missing in isoform 8.
VSP_046976Add
BLAST
Alternative sequencei1 – 4343Missing in isoform 5 and isoform 7.
VSP_045136Add
BLAST
Alternative sequencei7 – 6559Missing in isoform 4.
VSP_044743Add
BLAST
Alternative sequencei7 – 3024Missing in isoform 6.
VSP_046977Add
BLAST
Alternative sequencei8 – 3124KSKEQ…VDQKQ → VVGVTLKKKWHCLQKSDLTL AL in isoform 2.
VSP_010435Add
BLAST
Alternative sequencei32 – 6635Missing in isoform 3.
VSP_010436Add
BLAST
Alternative sequencei104 – 16865Missing in isoform 7.
VSP_046978Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti88 – 881E → K in BAH12041. 1 Publication
Sequence conflicti216 – 2161S → Y in AAH36183. 1 Publication
Sequence conflicti292 – 2921R → Q in BAH13081. 1 Publication
Sequence conflicti318 – 3181H → P in BAH11791. 1 Publication
Sequence conflicti409 – 4091H → Y in BAH12054. 1 Publication
Sequence conflicti474 – 4741P → T in AAH36183. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032592 mRNA. Translation: BAA92878.1.
AB032593 mRNA. Translation: BAA92879.1.
AK294501 mRNA. Translation: BAH11791.1.
AK295349 mRNA. Translation: BAH12041.1.
AK295386 mRNA. Translation: BAH12054.1.
AK299633 mRNA. Translation: BAH13081.1.
AK303716 mRNA. Translation: BAH14028.1.
AC007687 Genomic DNA. No translation available.
AC090024 Genomic DNA. No translation available.
AC092939 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW78382.1.
BC036183 mRNA. Translation: AAH36183.2.
AJ245503 mRNA. Translation: CAC01120.1. Different initiation.
CCDSiCCDS3236.1. [Q8IYB4-1]
CCDS58861.1. [Q8IYB4-8]
CCDS58862.1. [Q8IYB4-7]
CCDS58863.1. [Q8IYB4-5]
CCDS58864.1. [Q8IYB4-4]
CCDS58865.1. [Q8IYB4-6]
CCDS58866.1. [Q8IYB4-2]
CCDS58867.1. [Q8IYB4-3]
RefSeqiNP_001243679.1. NM_001256750.1. [Q8IYB4-2]
NP_001243680.1. NM_001256751.1. [Q8IYB4-6]
NP_001243681.1. NM_001256752.1. [Q8IYB4-3]
NP_001243682.1. NM_001256753.1. [Q8IYB4-4]
NP_001243683.1. NM_001256754.1. [Q8IYB4-5]
NP_001243684.1. NM_001256755.1. [Q8IYB4-7]
NP_001243685.1. NM_001256756.1. [Q8IYB4-8]
NP_057643.1. NM_016559.2. [Q8IYB4-1]
XP_006713719.1. XM_006713656.1. [Q8IYB4-5]
UniGeneiHs.235331.

Genome annotation databases

EnsembliENST00000263962; ENSP00000263962; ENSG00000114757. [Q8IYB4-2]
ENST00000392649; ENSP00000376420; ENSG00000114757. [Q8IYB4-7]
ENST00000464614; ENSP00000417270; ENSG00000114757. [Q8IYB4-7]
ENST00000465751; ENSP00000419348; ENSG00000114757. [Q8IYB4-6]
ENST00000467460; ENSP00000419975; ENSG00000114757. [Q8IYB4-1]
ENST00000468741; ENSP00000418665; ENSG00000114757. [Q8IYB4-8]
ENST00000472994; ENSP00000418054; ENSG00000114757. [Q8IYB4-4]
ENST00000476138; ENSP00000420555; ENSG00000114757. [Q8IYB4-5]
ENST00000485199; ENSP00000418440; ENSG00000114757. [Q8IYB4-3]
GeneIDi51555.
KEGGihsa:51555.
UCSCiuc003fki.2. human. [Q8IYB4-1]
uc003fkj.2. human. [Q8IYB4-3]
uc010hxd.2. human. [Q8IYB4-2]

Polymorphism databases

DMDMi47606040.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032592 mRNA. Translation: BAA92878.1 .
AB032593 mRNA. Translation: BAA92879.1 .
AK294501 mRNA. Translation: BAH11791.1 .
AK295349 mRNA. Translation: BAH12041.1 .
AK295386 mRNA. Translation: BAH12054.1 .
AK299633 mRNA. Translation: BAH13081.1 .
AK303716 mRNA. Translation: BAH14028.1 .
AC007687 Genomic DNA. No translation available.
AC090024 Genomic DNA. No translation available.
AC092939 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW78382.1 .
BC036183 mRNA. Translation: AAH36183.2 .
AJ245503 mRNA. Translation: CAC01120.1 . Different initiation.
CCDSi CCDS3236.1. [Q8IYB4-1 ]
CCDS58861.1. [Q8IYB4-8 ]
CCDS58862.1. [Q8IYB4-7 ]
CCDS58863.1. [Q8IYB4-5 ]
CCDS58864.1. [Q8IYB4-4 ]
CCDS58865.1. [Q8IYB4-6 ]
CCDS58866.1. [Q8IYB4-2 ]
CCDS58867.1. [Q8IYB4-3 ]
RefSeqi NP_001243679.1. NM_001256750.1. [Q8IYB4-2 ]
NP_001243680.1. NM_001256751.1. [Q8IYB4-6 ]
NP_001243681.1. NM_001256752.1. [Q8IYB4-3 ]
NP_001243682.1. NM_001256753.1. [Q8IYB4-4 ]
NP_001243683.1. NM_001256754.1. [Q8IYB4-5 ]
NP_001243684.1. NM_001256755.1. [Q8IYB4-7 ]
NP_001243685.1. NM_001256756.1. [Q8IYB4-8 ]
NP_057643.1. NM_016559.2. [Q8IYB4-1 ]
XP_006713719.1. XM_006713656.1. [Q8IYB4-5 ]
UniGenei Hs.235331.

3D structure databases

ProteinModelPortali Q8IYB4.
SMRi Q8IYB4. Positions 314-625.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119607. 1 interaction.
DIPi DIP-58547N.
STRINGi 9606.ENSP00000419975.

PTM databases

PhosphoSitei Q8IYB4.

Polymorphism databases

DMDMi 47606040.

Proteomic databases

PaxDbi Q8IYB4.
PRIDEi Q8IYB4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000263962 ; ENSP00000263962 ; ENSG00000114757 . [Q8IYB4-2 ]
ENST00000392649 ; ENSP00000376420 ; ENSG00000114757 . [Q8IYB4-7 ]
ENST00000464614 ; ENSP00000417270 ; ENSG00000114757 . [Q8IYB4-7 ]
ENST00000465751 ; ENSP00000419348 ; ENSG00000114757 . [Q8IYB4-6 ]
ENST00000467460 ; ENSP00000419975 ; ENSG00000114757 . [Q8IYB4-1 ]
ENST00000468741 ; ENSP00000418665 ; ENSG00000114757 . [Q8IYB4-8 ]
ENST00000472994 ; ENSP00000418054 ; ENSG00000114757 . [Q8IYB4-4 ]
ENST00000476138 ; ENSP00000420555 ; ENSG00000114757 . [Q8IYB4-5 ]
ENST00000485199 ; ENSP00000418440 ; ENSG00000114757 . [Q8IYB4-3 ]
GeneIDi 51555.
KEGGi hsa:51555.
UCSCi uc003fki.2. human. [Q8IYB4-1 ]
uc003fkj.2. human. [Q8IYB4-3 ]
uc010hxd.2. human. [Q8IYB4-2 ]

Organism-specific databases

CTDi 51555.
GeneCardsi GC03M179512.
HGNCi HGNC:30024. PEX5L.
HPAi HPA040216.
MIMi 611058. gene.
neXtProti NX_Q8IYB4.
PharmGKBi PA134892044.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0457.
HOGENOMi HOG000158146.
HOVERGENi HBG053575.
InParanoidi Q8IYB4.
OMAi QPLRGPE.
OrthoDBi EOG793B77.
PhylomeDBi Q8IYB4.
TreeFami TF315044.

Miscellaneous databases

GenomeRNAii 51555.
NextBioi 55344.
PROi Q8IYB4.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q8IYB4.
Bgeei Q8IYB4.
CleanExi HS_PEX5L.
Genevestigatori Q8IYB4.

Family and domain databases

Gene3Di 1.25.40.10. 2 hits.
InterProi IPR024112. PEX5-rel.
IPR024111. PTS1R_family.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR10130. PTHR10130. 1 hit.
PTHR10130:SF1. PTHR10130:SF1. 1 hit.
Pfami PF00515. TPR_1. 2 hits.
[Graphical view ]
SMARTi SM00028. TPR. 5 hits.
[Graphical view ]
PROSITEi PS50005. TPR. 5 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel peroxisomal targeting signal 1 receptor-like gene, PXR2, preferentially expressed in brain."
    Sano H., Snider J., Ohta M.
    Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4; 5; 6; 7 AND 8).
    Tissue: Amygdala, Brain, Corpus callosum and Kidney.
  3. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Brain.
  6. "Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals."
    Amery L., Sano H., Mannaerts G.P., Snider J., Van Looy J., Fransen M., Van Veldhoven P.P.
    Biochem. J. 357:635-646(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 264-626, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, POSSIBLE INTERACTION WITH PTS1 PROTEINS.
    Tissue: Liver.
  7. Cited for: VARIANT [LARGE SCALE ANALYSIS] THR-226.

Entry informationi

Entry nameiPEX5R_HUMAN
AccessioniPrimary (citable) accession number: Q8IYB4
Secondary accession number(s): B7Z2A5
, B7Z305, B7Z318, B7Z5Z5, B7Z8P2, E7EUV8, E7EUZ0, E9PEC1, E9PH97, Q9NQD1, Q9P2U3, Q9P2U4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: July 9, 2014
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi