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Q8IYB0 (YK038_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative uncharacterized protein MGC39545
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length196 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 196196Putative uncharacterized protein MGC39545
PRO_0000342657

Natural variations

Natural variant1291D → Y in a colorectal cancer sample; somatic mutation. Ref.3
VAR_044325

Experimental info

Sequence conflict631L → P in AAH36197. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q8IYB0 [UniParc].

Last modified July 1, 2008. Version 2.
Checksum: 29D68226D9E1BFC9

FASTA19621,182
        10         20         30         40         50         60 
MPSGEERRDR QKGRRAGCDT SSTPSNTAPR IPEPGAHPTA ARPATAQPPR SLLPPVCSKT 

        70         80         90        100        110        120 
IALPASAAAA SGSDTAGMRG LGKAPHSGEG HERGRGNSKM KACNNYQYGY LAKPDTSFWI 

       130        140        150        160        170        180 
KCRRWLLADA GRHTQRPFWT FRVSHSPLLE AEAGRPSDVS QLQLGSDLKP KMRRPAGELF 

       190 
SPKDAGWELD PAEKSE 

« Hide

References

[1]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[3]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANT [LARGE SCALE ANALYSIS] TYR-129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP000708 Genomic DNA. No translation available.
BC036197 mRNA. Translation: AAH36197.1.
UniGeneHs.450611.

3D structure databases

ProteinModelPortalQ8IYB0.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ8IYB0.

Proteomic databases

PRIDEQ8IYB0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc001qbz.1. human.

Organism-specific databases

GeneCardsGC11P125366.
HPAHPA051125.
neXtProtNX_Q8IYB0.

Phylogenomic databases

InParanoidQ8IYB0.
OMAHSGEGHE.
PhylomeDBQ8IYB0.

Gene expression databases

BgeeQ8IYB0.
GenevestigatorQ8IYB0.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameYK038_HUMAN
AccessionPrimary (citable) accession number: Q8IYB0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 1, 2008
Last modified: January 22, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM