Q8IYB0 (YK038_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Putative uncharacterized protein MGC39545
Organism	Homo sapiens (Human) [Reference proteome]
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Putative uncharacterized protein MGC39545		PRO_0000342657
Natural variations
	Natural variant	129	1	D → Y in a colorectal cancer sample; somatic mutation. Ref.3		VAR_044325
Experimental info
	Sequence conflict	63	1	L → P in AAH36197. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q8IYB0 [UniParc]. Last modified July 1, 2008. Version 2. Checksum: 29D68226D9E1BFC9	FASTA	196	21,182
	10 20 30 40 50 60 MPSGEERRDR QKGRRAGCDT SSTPSNTAPR IPEPGAHPTA ARPATAQPPR SLLPPVCSKT 70 80 90 100 110 120 IALPASAAAA SGSDTAGMRG LGKAPHSGEG HERGRGNSKM KACNNYQYGY LAKPDTSFWI 130 140 150 160 170 180 KCRRWLLADA GRHTQRPFWT FRVSHSPLLE AEAGRPSDVS QLQLGSDLKP KMRRPAGELF 190 SPKDAGWELD PAEKSE

References

[1]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
[3]	"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E. Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANT [LARGE SCALE ANALYSIS] TYR-129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP000708 Genomic DNA. No translation available. BC036197 mRNA. Translation: AAH36197.1.
IPI	IPI00217747.
UniGene	Hs.450611.
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q8IYB0.
Proteomic databases
PRIDE	Q8IYB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc001qbz.1. human.
Organism-specific databases
GeneCards	GC11P125366.
HPA	HPA051125.
neXtProt	NX_Q8IYB0.
Phylogenomic databases
InParanoid	Q8IYB0.
OMA	EGHERGR.
PhylomeDB	Q8IYB0.
Gene expression databases
Bgee	Q8IYB0.
Genevestigator	Q8IYB0.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

YK038_HUMAN

Accession

Primary (citable) accession number: Q8IYB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.