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Protein
Submitted name:

ACTR2 protein

Gene

ACTR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ8IY98.

Names & Taxonomyi

Protein namesi
Submitted name:
ACTR2 proteinImported
Gene namesi
Name:ACTR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ8IY98.
PeptideAtlasiQ8IY98.
PRIDEiQ8IY98.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000367220.

Structurei

3D structure databases

ProteinModelPortaliQ8IY98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0677. Eukaryota.
COG5277. LUCA.
HOVERGENiHBG003771.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR027306. Arp2.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF149. PTHR11937:SF149. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IY98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGDEASELR SMLEVNYPME NGIVRNWDDM KHLWDYTFGP EKLNIDTRNC
60 70 80 90 100
KILLTEPPMN PTKNREKIVE VMFETYQFSG VYVAIQAVLT LYAQGLLTGV
110 120 130 140 150
VVDSGDGVTH ICPVYEGFSL PHLTRRLDIA GRDITRYLIK LLLLRGYAFN
160 170 180 190 200
HSADFETVRM IKEKLCYVGY NIEQEQKLAL ETTVLVESYT LPDGRIIKVG
210 220 230 240 250
GERFEAPEAL FQPHLINVEG VGVAELLFNT IQAADIDTRS EFYKHIVLSG
260 270 280 290 300
GSTMYPGLPS RLERELKQLY LERVLKGDVE KLSKFKISIE DPPRRKHMVF
310 320 330
LGGAVLADIM KDKDNFWMTR QEYQEKGVRV LEKLGVTVR
Length:339
Mass (Da):38,773
Last modified:March 1, 2003 - v1
Checksum:i37E4F79A189CA255
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC036253 mRNA. Translation: AAH36253.1.
UniGeneiHs.643727.
Hs.744913.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC036253 mRNA. Translation: AAH36253.1.
UniGeneiHs.643727.
Hs.744913.

3D structure databases

ProteinModelPortaliQ8IY98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000367220.

Proteomic databases

PaxDbiQ8IY98.
PeptideAtlasiQ8IY98.
PRIDEiQ8IY98.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0677. Eukaryota.
COG5277. LUCA.
HOVERGENiHBG003771.

Enzyme and pathway databases

SignaLinkiQ8IY98.

Miscellaneous databases

ChiTaRSiACTR2. human.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR027306. Arp2.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF149. PTHR11937:SF149. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IY98_HUMAN
AccessioniPrimary (citable) accession number: Q8IY98
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.