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Protein

AP-1 complex subunit gamma

Gene

AP1G1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
AP-1 complex subunit gammaUniRule annotation
Gene namesi
Name:AP1G1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24845

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8IY97
PRIDEiQ8IY97

Expressioni

Gene expression databases

GenevisibleiQ8IY97 HS

Interactioni

Protein-protein interaction databases

IntActiQ8IY97, 1 interactor
MINTiQ8IY97

Structurei

3D structure databases

ProteinModelPortaliQ8IY97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini705 – 820GAEInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the adaptor complexes large subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1062 Eukaryota
ENOG410XPKK LUCA
HOGENOMiHOG000210271
HOVERGENiHBG067473
KOiK12391

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR017107 AP1_complex_gsu
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR008152 Clathrin_a/b/g-adaptin_app_Ig
IPR013041 Clathrin_app_Ig-like_sf
IPR008153 GAE_dom
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF02883 Alpha_adaptinC2, 1 hit
PIRSFiPIRSF037094 AP1_complex_gamma, 1 hit
SMARTiView protein in SMART
SM00809 Alpha_adaptinC2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
PROSITEiView protein in PROSITE
PS50180 GAE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IY97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAPIRLREL IRTIRTARTQ AEEREMIQKE CAAIRSSFRE EDNTYRCRNV
60 70 80 90 100
AKLLYMHMLG YPAHFGQLEC FKLIASQKFT DKRIGYLGAM LLLDERQDVH
110 120 130 140 150
LLMTNCIKND LNHSTQFVQG LALCTLGCMG SSEMCRDLAG EVEKLLKTSN
160 170 180 190 200
SYLRKKAALC AVHVIRKVPE LMEMFLPATK NLLNEKNHGV LHTSVVLLTE
210 220 230 240 250
MCERSPDMLA HFRKNEKLVP QLVRILKNLI MSGYSPEHDV SGISDPFLQV
260 270 280 290 300
RILRLLRILG RNDDDSSEAM NDILAQVATN TETSKNVGNA ILYETVLTIM
310 320 330 340 350
DIKSESGLRV LAINILGRFL LNNDKNIRYV ALTSLLKTVQ TDHNAVQRHR
360 370 380 390 400
STIVDCLKDL DVSIKRRAME LSFALVNGNN IRGMMKELLY FLDSCEPEFK
410 420 430 440 450
ADCASGIFLA AEKYAPSKRW HIDTIMRVLT TAGSYVRDDA VPNLIQLITN
460 470 480 490 500
SVEMHAYTVQ RLYKAILGDY SQQPLVQVAA WCIGEYGDLL VSGQCEEEEP
510 520 530 540 550
IQVTEDEVLD ILESVLISNM STSVTRGYAL TAIMKLSTRF TCTVNRIKKV
560 570 580 590 600
VSIYGSSIDV ELQQRAVEYN ALFKKYDHMR SALLERMPVM EKVTTNGPTE
610 620 630 640 650
IVQTNGETEP APLETKPPPS GPQPTSQAND LLDLLGGNDI TPVIPTAPTS
660 670 680 690 700
KPSSAGGELL DLLGDINLTG APAAAPAPAS VPQISQPPFL LDGLSSQPLF
710 720 730 740 750
NDIAAGIPSI TAYSKNGLKI EFTFERSNTN PSVTVITIQA SNSTELDMTD
760 770 780 790 800
FVFQAAVPKT FQLQLLSPSS SIVPAFNTGT ITQVIKVLNP QKQQLRMRIK
810 820
LTYNHKGSAM QDLAEVNNFP PQSWQ
Length:825
Mass (Da):91,757
Last modified:March 1, 2003 - v1
Checksum:i0FBEA78600892003
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC036283 mRNA Translation: AAH36283.1
PIRiT14753
RefSeqiNP_001025178.1, NM_001030007.1
NP_001119.3, NM_001128.5
UniGeneiHs.461253

Genome annotation databases

GeneIDi164
KEGGihsa:164

Similar proteinsi

Entry informationi

Entry nameiQ8IY97_HUMAN
AccessioniPrimary (citable) accession number: Q8IY97
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health