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Q8IY81

- SPB1_HUMAN

UniProt

Q8IY81 - SPB1_HUMAN

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Protein
pre-rRNA processing protein FTSJ3
Gene
FTSJ3, SB92
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.1 Publication

Catalytic activityi

S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylnucleoside.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 561S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding sitei58 – 581S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding sitei76 – 761S-adenosyl-L-methionine By similarity
Binding sitei92 – 921S-adenosyl-L-methionine By similarity
Binding sitei117 – 1171S-adenosyl-L-methionine By similarity
Active sitei157 – 1571Proton acceptor By similarity

GO - Molecular functioni

  1. poly(A) RNA binding Source: UniProtKB
  2. protein binding Source: IntAct
  3. rRNA methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
pre-rRNA processing protein FTSJ3 (EC:2.1.1.-)
Alternative name(s):
2'-O-ribose RNA methyltransferase SPB1 homolog
Protein ftsJ homolog 3
Putative rRNA methyltransferase 3
Gene namesi
Name:FTSJ3
ORF Names:SB92
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:17136. FTSJ3.

Subcellular locationi

Nucleusnucleolus 2 Publications

GO - Cellular componenti

  1. nucleolus Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28419.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 847847pre-rRNA processing protein FTSJ3UniRule annotation
PRO_0000155577Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei333 – 3331Phosphoserine3 Publications
Modified residuei335 – 3351Phosphoserine3 Publications
Modified residuei336 – 3361Phosphoserine4 Publications
Modified residuei347 – 3471Phosphoserine1 Publication
Modified residuei356 – 3561Phosphoserine1 Publication
Modified residuei371 – 3711Phosphothreonine1 Publication
Modified residuei392 – 3921Citrulline By similarity
Modified residuei549 – 5491Phosphoserine1 Publication
Modified residuei584 – 5841Phosphoserine3 Publications
Modified residuei644 – 6441Phosphoserine3 Publications
Modified residuei676 – 6761Phosphoserine1 Publication
Modified residuei688 – 6881Phosphoserine1 Publication
Modified residuei783 – 7831Citrulline By similarity

Post-translational modificationi

Citrullinated by PADI4 By similarity.UniRule annotation

Keywords - PTMi

Citrullination, Phosphoprotein

Proteomic databases

MaxQBiQ8IY81.
PaxDbiQ8IY81.
PRIDEiQ8IY81.

2D gel databases

SWISS-2DPAGEQ8IY81.

PTM databases

PhosphoSiteiQ8IY81.

Expressioni

Gene expression databases

ArrayExpressiQ8IY81.
BgeeiQ8IY81.
CleanExiHS_FTSJ3.
GenevestigatoriQ8IY81.

Organism-specific databases

HPAiHPA055544.

Interactioni

Subunit structurei

Interacts with NIP7.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
EIF2AK2P195252EBI-744088,EBI-640775
OAS3Q9Y6K52EBI-744088,EBI-6115729

Protein-protein interaction databases

BioGridi125581. 55 interactions.
IntActiQ8IY81. 12 interactions.
MINTiMINT-1468947.
STRINGi9606.ENSP00000337518.

Structurei

3D structure databases

ProteinModelPortaliQ8IY81.
SMRiQ8IY81. Positions 23-199.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili355 – 40753 Reviewed prediction
Add
BLAST
Coiled coili739 – 77739 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG0293.
HOVERGENiHBG075246.
InParanoidiQ8IY81.
KOiK14857.
OMAiDLPEWFV.
OrthoDBiEOG7WX07S.
PhylomeDBiQ8IY81.
TreeFamiTF106102.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01547. RNA_methyltr_E.
MF_03163. RNA_methyltr_E_SPB1.
InterProiIPR015507. rRNA-MeTfrase_E.
IPR012920. rRNA_MeTfrase_Spb1_C.
IPR024576. rRNA_MeTfrase_Spb1_DUF3381.
IPR002877. rRNA_MeTrfase_FtsJ_dom.
IPR029063. SAM-dependent_MTases-like.
IPR028589. Spb1.
[Graphical view]
PANTHERiPTHR10920. PTHR10920. 1 hit.
PTHR10920:SF13. PTHR10920:SF13. 1 hit.
PfamiPF11861. DUF3381. 1 hit.
PF01728. FtsJ. 1 hit.
PF07780. Spb1_C. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IY81-1 [UniParc]FASTAAdd to Basket

« Hide

MGKKGKVGKS RRDKFYHLAK ETGYRSRSAF KLIQLNRRFQ FLQKARALLD    50
LCAAPGGWLQ VAAKFMPVSS LIVGVDLVPI KPLPNVVTLQ QDITTERCRQ 100
ALRKELKTWK VDVVLNDGAP NVGASWVHDA YSQAHLTLMA LRLACDFLAR 150
GGSFITKVFR SRDYQPLLWI FQQLFRRVQA TKPQASRHES AEIFVVCQGF 200
LAPDKVDSKF FDPKFAFKEV EVQAKTVTEL VTKKKPKAEG YAEGDLTLYH 250
RTSVTDFLRA ANPVDFLSKA SEIMVDDEEL AQHPATTEDI RVCCQDIRVL 300
GRKELRSLLN WRTKLRRYVA KKLKEQAKAL DISLSSGEED EGDEEDSTAG 350
TTKQPSKEEE EEEEEEQLNQ TLAEMKAQEV AELKRKKKKL LREQRKQRER 400
VELKMDLPGV SIADEGETGM FSLSTIRGHQ LLEEVTQGDM SAADTFLSDL 450
PRDDIYVSDV EDDGDDTSLD SDLDPEELAG VRGHQGLRDQ KRMRLTEVQD 500
DKEEEEEENP LLVPLEEKAV LQEEQANLWF SKGSFAGIED DADEALEISQ 550
AQLLFENRRK GRQQQQKQQL PQTPPSCLKT EIMSPLYQDE APKGTEASSG 600
TEAATGLEGE EKDGISDSDS STSSEEEESW EPLRGKKRSR GPKSDDDGFE 650
IVPIEDPAKH RILDPEGLAL GAVIASSKKA KRDLIDNSFN RYTFNEDEGE 700
LPEWFVQEEK QHRIRQLPVG KKEVEHYRKR WREINARPIK KVAEAKARKK 750
RRMLKRLEQT RKKAEAVVNT VDISEREKVA QLRSLYKKAG LGKEKRHVTY 800
VVAKKGVGRK VRRPAGVRGH FKVVDSRMKK DQRAQQRKEQ KKKHKRK 847
Length:847
Mass (Da):96,558
Last modified:May 18, 2010 - v2
Checksum:i06B2F4D28A48026F
GO

Sequence cautioni

The sequence BAA90924.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti91 – 911Q → E.3 Publications
Corresponds to variant rs2584625 [ dbSNP | Ensembl ].
VAR_023284
Natural varianti424 – 4241S → C.4 Publications
Corresponds to variant rs2727288 [ dbSNP | Ensembl ].
VAR_023285

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti278 – 2781E → I in AAL56015. 1 Publication
Sequence conflicti278 – 2781E → I in BAA90924. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF327355 mRNA. Translation: AAL56015.1.
AK000069 mRNA. Translation: BAA90924.1. Different initiation.
AK315010 mRNA. Translation: BAG37502.1.
AC015651 Genomic DNA. No translation available.
CH471109 Genomic DNA. Translation: EAW94273.1.
CH471109 Genomic DNA. Translation: EAW94274.1.
CH471109 Genomic DNA. Translation: EAW94275.1.
BC000131 mRNA. Translation: AAH00131.2.
BC036710 mRNA. Translation: AAH36710.1.
AL834482 mRNA. Translation: CAD39141.1.
CCDSiCCDS11644.1.
RefSeqiNP_060117.3. NM_017647.3.
UniGeneiHs.463785.

Genome annotation databases

EnsembliENST00000427159; ENSP00000396673; ENSG00000108592.
GeneIDi117246.
KEGGihsa:117246.
UCSCiuc002jbz.3. human.

Polymorphism databases

DMDMi296452883.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF327355 mRNA. Translation: AAL56015.1 .
AK000069 mRNA. Translation: BAA90924.1 . Different initiation.
AK315010 mRNA. Translation: BAG37502.1 .
AC015651 Genomic DNA. No translation available.
CH471109 Genomic DNA. Translation: EAW94273.1 .
CH471109 Genomic DNA. Translation: EAW94274.1 .
CH471109 Genomic DNA. Translation: EAW94275.1 .
BC000131 mRNA. Translation: AAH00131.2 .
BC036710 mRNA. Translation: AAH36710.1 .
AL834482 mRNA. Translation: CAD39141.1 .
CCDSi CCDS11644.1.
RefSeqi NP_060117.3. NM_017647.3.
UniGenei Hs.463785.

3D structure databases

ProteinModelPortali Q8IY81.
SMRi Q8IY81. Positions 23-199.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 125581. 55 interactions.
IntActi Q8IY81. 12 interactions.
MINTi MINT-1468947.
STRINGi 9606.ENSP00000337518.

PTM databases

PhosphoSitei Q8IY81.

Polymorphism databases

DMDMi 296452883.

2D gel databases

SWISS-2DPAGE Q8IY81.

Proteomic databases

MaxQBi Q8IY81.
PaxDbi Q8IY81.
PRIDEi Q8IY81.

Protocols and materials databases

DNASUi 117246.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000427159 ; ENSP00000396673 ; ENSG00000108592 .
GeneIDi 117246.
KEGGi hsa:117246.
UCSCi uc002jbz.3. human.

Organism-specific databases

CTDi 117246.
GeneCardsi GC17M061896.
HGNCi HGNC:17136. FTSJ3.
HPAi HPA055544.
neXtProti NX_Q8IY81.
PharmGKBi PA28419.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0293.
HOVERGENi HBG075246.
InParanoidi Q8IY81.
KOi K14857.
OMAi DLPEWFV.
OrthoDBi EOG7WX07S.
PhylomeDBi Q8IY81.
TreeFami TF106102.

Miscellaneous databases

ChiTaRSi FTSJ3. human.
GeneWikii FTSJ3.
GenomeRNAii 117246.
NextBioi 80174.
PROi Q8IY81.

Gene expression databases

ArrayExpressi Q8IY81.
Bgeei Q8IY81.
CleanExi HS_FTSJ3.
Genevestigatori Q8IY81.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01547. RNA_methyltr_E.
MF_03163. RNA_methyltr_E_SPB1.
InterProi IPR015507. rRNA-MeTfrase_E.
IPR012920. rRNA_MeTfrase_Spb1_C.
IPR024576. rRNA_MeTfrase_Spb1_DUF3381.
IPR002877. rRNA_MeTrfase_FtsJ_dom.
IPR029063. SAM-dependent_MTases-like.
IPR028589. Spb1.
[Graphical view ]
PANTHERi PTHR10920. PTHR10920. 1 hit.
PTHR10920:SF13. PTHR10920:SF13. 1 hit.
Pfami PF11861. DUF3381. 1 hit.
PF01728. FtsJ. 1 hit.
PF07780. Spb1_C. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Zhang W., Li N., Wan T., Chen T., Cao T.
    Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLU-91 AND CYS-424.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLU-91 AND CYS-424.
    Tissue: Colon and Placenta.
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLU-91 AND CYS-424.
    Tissue: Placenta and Skin.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 157-847, VARIANT CYS-424.
    Tissue: Melanoma.
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-335; SER-336 AND SER-347, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-335; SER-336; SER-356; THR-371; SER-549; SER-584 AND SER-644, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  14. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-336; SER-584; SER-644; SER-676 AND SER-688, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. "The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing."
    Morello L.G., Coltri P.P., Quaresma A.J., Simabuco F.M., Silva T.C., Singh G., Nickerson J.A., Oliveira C.C., Moore M.J., Zanchin N.I.
    PLoS ONE 6:E29174-E29174(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH NIP7, SUBCELLULAR LOCATION.
  18. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-335; SER-336; SER-584 AND SER-644, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  19. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSPB1_HUMAN
AccessioniPrimary (citable) accession number: Q8IY81
Secondary accession number(s): B2RCA5
, D3DU22, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: May 18, 2010
Last modified: September 3, 2014
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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