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Q8IY57

- YAF2_HUMAN

UniProt

Q8IY57 - YAF2_HUMAN

Protein

YY1-associated factor 2

Gene

YAF2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 116 (01 Oct 2014)
      Sequence version 3 (25 Nov 2008)
      Previous versions | rss
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    Functioni

    Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.3 Publications

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri19 – 4830RanBP2-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. protein binding Source: UniProtKB
    2. transcription coactivator activity Source: UniProtKB
    3. transcription corepressor activity Source: UniProtKB
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. negative regulation of transcription, DNA-templated Source: UniProtKB
    2. positive regulation of transcription, DNA-templated Source: UniProtKB
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    YY1-associated factor 2
    Gene namesi
    Name:YAF2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:17363. YAF2.

    Subcellular locationi

    Nucleus 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. nucleus Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38236.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 180180YY1-associated factor 2PRO_0000066113Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei167 – 1671Phosphoserine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ8IY57.
    PaxDbiQ8IY57.
    PRIDEiQ8IY57.

    PTM databases

    PhosphoSiteiQ8IY57.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8IY57.
    BgeeiQ8IY57.
    CleanExiHS_YAF2.
    GenevestigatoriQ8IY57.

    Organism-specific databases

    HPAiHPA026867.

    Interactioni

    Subunit structurei

    Interacts with MYC, MYCN, RNF2/RING1B and YY1. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2.4 Publications

    Protein-protein interaction databases

    BioGridi115441. 29 interactions.
    DIPiDIP-44919N.
    IntActiQ8IY57. 9 interactions.
    MINTiMINT-1521451.
    STRINGi9606.ENSP00000328004.

    Structurei

    Secondary structure

    1
    180
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi26 – 283
    Beta strandi40 – 423

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2D9GNMR-A19-58[»]
    ProteinModelPortaliQ8IY57.
    SMRiQ8IY57. Positions 19-58, 101-133.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8IY57.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 RanBP2-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri19 – 4830RanBP2-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG268430.
    HOGENOMiHOG000007553.
    HOVERGENiHBG001768.
    InParanoidiQ8IY57.
    KOiK11468.
    OMAiRRNIVHR.
    OrthoDBiEOG7B8S61.
    PhylomeDBiQ8IY57.
    TreeFamiTF350501.

    Family and domain databases

    InterProiIPR001876. Znf_RanBP2.
    [Graphical view]
    PfamiPF00641. zf-RanBP. 1 hit.
    [Graphical view]
    SMARTiSM00547. ZnF_RBZ. 1 hit.
    [Graphical view]
    PROSITEiPS01358. ZF_RANBP2_1. 1 hit.
    PS50199. ZF_RANBP2_2. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8IY57-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGDKKSPTRP KRQPKPSSDE GYWDCSVCTF RNSAEAFKCM MCDVRKGTST    50
    RKPRPVSQLV AQQVTQQFVP PTQSKKEKKD KVEKEKSEKE TTSKKNSHKK 100
    TRPRLKNVDR SSAQHLEVTV GDLTVIITDF KEKTKSPPAS SAASADQHSQ 150
    SGSSSDNTER GMSRSSSPRG EASSLNGESH 180
    Length:180
    Mass (Da):19,901
    Last modified:November 25, 2008 - v3
    Checksum:i199A56EE06BB4FBE
    GO
    Isoform 2 (identifier: Q8IY57-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         50-50: T → TRSTLFEVIVSASRTKEPLKFPISG

    Note: No experimental confirmation available.

    Show »
    Length:204
    Mass (Da):22,546
    Checksum:i16C4D290C18BD880
    GO
    Isoform 3 (identifier: Q8IY57-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         8-49: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:138
    Mass (Da):15,115
    Checksum:i3E1E2E64F1003EC5
    GO
    Isoform 4 (identifier: Q8IY57-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         52-117: KPRPVSQLVA...VDRSSAQHLE → DSKEGGKLVS...QRSGPSLKEA
         118-180: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:117
    Mass (Da):12,738
    Checksum:i7A8B9E3A734AF65F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti13 – 142QP → HA in AAC51116. (PubMed:9016636)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei8 – 4942Missing in isoform 3. 1 PublicationVSP_043415Add
    BLAST
    Alternative sequencei50 – 501T → TRSTLFEVIVSASRTKEPLK FPISG in isoform 2. 1 PublicationVSP_055659
    Alternative sequencei52 – 11766KPRPV…AQHLE → DSKEGGKLVSYSTASLGVRG TLRNRVGGGSSEEKKQAEYL APGRRRNIVHRGVGPGQRSG PSLKEA in isoform 4. 1 PublicationVSP_044598Add
    BLAST
    Alternative sequencei118 – 18063Missing in isoform 4. 1 PublicationVSP_044599Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U72209 mRNA. Translation: AAC51116.1.
    AK127531 mRNA. No translation available.
    AK291355 mRNA. Translation: BAF84044.1.
    AK294260 mRNA. Translation: BAG57554.1.
    AC020629 Genomic DNA. No translation available.
    CH471111 Genomic DNA. Translation: EAW57839.1.
    BC037777 mRNA. Translation: AAH37777.1.
    CCDSiCCDS31775.1. [Q8IY57-1]
    CCDS53778.1. [Q8IY57-3]
    CCDS53780.1. [Q8IY57-4]
    RefSeqiNP_001177906.1. NM_001190977.1. [Q8IY57-3]
    NP_001177908.1. NM_001190979.1.
    NP_001177909.1. NM_001190980.1. [Q8IY57-4]
    NP_005739.2. NM_005748.4. [Q8IY57-1]
    UniGeneiHs.649195.
    Hs.708084.

    Genome annotation databases

    GeneIDi10138.
    KEGGihsa:10138.
    UCSCiuc001rmv.3. human. [Q8IY57-1]
    uc010skp.2. human. [Q8IY57-3]

    Polymorphism databases

    DMDMi215274199.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U72209 mRNA. Translation: AAC51116.1 .
    AK127531 mRNA. No translation available.
    AK291355 mRNA. Translation: BAF84044.1 .
    AK294260 mRNA. Translation: BAG57554.1 .
    AC020629 Genomic DNA. No translation available.
    CH471111 Genomic DNA. Translation: EAW57839.1 .
    BC037777 mRNA. Translation: AAH37777.1 .
    CCDSi CCDS31775.1. [Q8IY57-1 ]
    CCDS53778.1. [Q8IY57-3 ]
    CCDS53780.1. [Q8IY57-4 ]
    RefSeqi NP_001177906.1. NM_001190977.1. [Q8IY57-3 ]
    NP_001177908.1. NM_001190979.1.
    NP_001177909.1. NM_001190980.1. [Q8IY57-4 ]
    NP_005739.2. NM_005748.4. [Q8IY57-1 ]
    UniGenei Hs.649195.
    Hs.708084.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2D9G NMR - A 19-58 [» ]
    ProteinModelPortali Q8IY57.
    SMRi Q8IY57. Positions 19-58, 101-133.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 115441. 29 interactions.
    DIPi DIP-44919N.
    IntActi Q8IY57. 9 interactions.
    MINTi MINT-1521451.
    STRINGi 9606.ENSP00000328004.

    PTM databases

    PhosphoSitei Q8IY57.

    Polymorphism databases

    DMDMi 215274199.

    Proteomic databases

    MaxQBi Q8IY57.
    PaxDbi Q8IY57.
    PRIDEi Q8IY57.

    Protocols and materials databases

    DNASUi 10138.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 10138.
    KEGGi hsa:10138.
    UCSCi uc001rmv.3. human. [Q8IY57-1 ]
    uc010skp.2. human. [Q8IY57-3 ]

    Organism-specific databases

    CTDi 10138.
    GeneCardsi GC12M042550.
    HGNCi HGNC:17363. YAF2.
    HPAi HPA026867.
    MIMi 607534. gene.
    neXtProti NX_Q8IY57.
    PharmGKBi PA38236.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG268430.
    HOGENOMi HOG000007553.
    HOVERGENi HBG001768.
    InParanoidi Q8IY57.
    KOi K11468.
    OMAi RRNIVHR.
    OrthoDBi EOG7B8S61.
    PhylomeDBi Q8IY57.
    TreeFami TF350501.

    Miscellaneous databases

    ChiTaRSi YAF2. human.
    EvolutionaryTracei Q8IY57.
    GeneWikii YAF2.
    GenomeRNAii 10138.
    NextBioi 38355.
    PROi Q8IY57.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8IY57.
    Bgeei Q8IY57.
    CleanExi HS_YAF2.
    Genevestigatori Q8IY57.

    Family and domain databases

    InterProi IPR001876. Znf_RanBP2.
    [Graphical view ]
    Pfami PF00641. zf-RanBP. 1 hit.
    [Graphical view ]
    SMARTi SM00547. ZnF_RBZ. 1 hit.
    [Graphical view ]
    PROSITEi PS01358. ZF_RANBP2_1. 1 hit.
    PS50199. ZF_RANBP2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1."
      Kalenik J.L., Chen D., Bradley M.E., Chen S.-J., Lee T.-C.
      Nucleic Acids Res. 25:843-849(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH YY1.
      Tissue: Skeletal muscle.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4).
      Tissue: Amygdala, Brain and Thalamus.
    3. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Brain.
    6. "Functional interaction of Yaf2 with the central region of MycN."
      Bannasch D., Maedge B., Schwab M.
      Oncogene 20:5913-5919(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH MYCN.
    7. "A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells."
      Ogawa H., Ishiguro K., Gaubatz S., Livingston D.M., Nakatani Y.
      Science 296:1132-1136(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN COMPLEX WITH E2F6; TFDP1; MAX; MGA; EUHMTASE1; CBX3; RING1; RNF2; MBLR; L3MBTL2 AND BAT8.
    8. Cited for: FUNCTION, INTERACTION WITH MYC.
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic kidney.
    10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-167, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-167, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    12. "Solution structure of the ZF-RANBP domain of YY1-associated factor 2."
      RIKEN structural genomics initiative (RSGI)
      Submitted (JUN-2006) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 17-58.

    Entry informationi

    Entry nameiYAF2_HUMAN
    AccessioniPrimary (citable) accession number: Q8IY57
    Secondary accession number(s): A8K5P0
    , B4DFU3, G3V465, Q99710
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2003
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 116 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3