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Q8IY42 (CD019_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized protein C4orf19
Gene names
Name:C4orf19
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 314314Uncharacterized protein C4orf19
PRO_0000286561

Amino acid modifications

Modified residue1061Phosphothreonine By similarity

Natural variations

Natural variant391D → E.
Corresponds to variant rs6852908 [ dbSNP | Ensembl ].
VAR_050770
Natural variant1511A → T.
Corresponds to variant rs2973275 [ dbSNP | Ensembl ].
VAR_032118
Natural variant2741E → G. Ref.1
Corresponds to variant rs3733500 [ dbSNP | Ensembl ].
VAR_032119

Sequences

Sequence LengthMass (Da)Tools
Q8IY42 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 65A8FEBD0F1B08EA

FASTA31433,742
        10         20         30         40         50         60 
MGCRCCKIIQ SYLFDPVQVP SPGYVNEVNS CKLDEDDTDK LKGKWSSEVL VQKNDPQRQG 

        70         80         90        100        110        120 
SKKTESSSRT ADPWEPCWPH QGPLPQGDAG GEHHACGVNG IGPAATPQPT GNSSPTQDDR 

       130        140        150        160        170        180 
GSWASTANTV PPTQPFLEGG GTRKQDCVLL ASEGTQVMRN GDSRAPSEAE SFALEVQDHV 

       190        200        210        220        230        240 
FQIPAPDYLQ HWGPAGDNVD HNEKDCVFKN HTEDESLEGI QPPVGEHGLN TPFSVRRSWD 

       250        260        270        280        290        300 
SLNEDVETEV LSICFNEKGP VHAMPVVDSG NRQEDTHGSD GDGDGEIVDE DAAVAEALAA 

       310 
LEAATAGEDL DETD 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT GLY-274.
Tissue: Placenta.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK001879 mRNA. Translation: BAA91958.1.
BC037906 mRNA. Translation: AAH37906.1.
RefSeqNP_001098099.1. NM_001104629.1.
NP_060772.2. NM_018302.2.
XP_005262714.1. XM_005262657.1.
UniGeneHs.107527.

3D structure databases

ProteinModelPortalQ8IY42.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000284437.

PTM databases

PhosphoSiteQ8IY42.

Polymorphism databases

DMDM74728286.

Proteomic databases

PaxDbQ8IY42.
PRIDEQ8IY42.

Protocols and materials databases

DNASU55286.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000284437; ENSP00000284437; ENSG00000154274.
ENST00000381980; ENSP00000371408; ENSG00000154274.
GeneID55286.
KEGGhsa:55286.
UCSCuc003gsw.4. human.

Organism-specific databases

CTD55286.
GeneCardsGC04P037455.
HGNCHGNC:25618. C4orf19.
HPAHPA043458.
neXtProtNX_Q8IY42.
PharmGKBPA144596500.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG44497.
HOGENOMHOG000111464.
HOVERGENHBG099521.
InParanoidQ8IY42.
OMAIQSYLFD.
OrthoDBEOG7B31NT.
PhylomeDBQ8IY42.
TreeFamTF337421.

Gene expression databases

ArrayExpressQ8IY42.
BgeeQ8IY42.
CleanExHS_C4orf19.
GenevestigatorQ8IY42.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi55286.
NextBio59452.

Entry information

Entry nameCD019_HUMAN
AccessionPrimary (citable) accession number: Q8IY42
Secondary accession number(s): Q9NV03
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 4

Human chromosome 4: entries, gene names and cross-references to MIM