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Q8IY42

- CD019_HUMAN

UniProt

Q8IY42 - CD019_HUMAN

Protein

Uncharacterized protein C4orf19

Gene

C4orf19

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C4orf19
    Gene namesi
    Name:C4orf19
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:25618. C4orf19.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA144596500.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 314314Uncharacterized protein C4orf19PRO_0000286561Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei106 – 1061PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ8IY42.
    PRIDEiQ8IY42.

    PTM databases

    PhosphoSiteiQ8IY42.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8IY42.
    BgeeiQ8IY42.
    CleanExiHS_C4orf19.
    GenevestigatoriQ8IY42.

    Organism-specific databases

    HPAiHPA043458.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000284437.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IY42.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG44497.
    HOGENOMiHOG000111464.
    HOVERGENiHBG099521.
    InParanoidiQ8IY42.
    OMAiQIPAPDY.
    OrthoDBiEOG7B31NT.
    PhylomeDBiQ8IY42.
    TreeFamiTF337421.

    Sequencei

    Sequence statusi: Complete.

    Q8IY42-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGCRCCKIIQ SYLFDPVQVP SPGYVNEVNS CKLDEDDTDK LKGKWSSEVL    50
    VQKNDPQRQG SKKTESSSRT ADPWEPCWPH QGPLPQGDAG GEHHACGVNG 100
    IGPAATPQPT GNSSPTQDDR GSWASTANTV PPTQPFLEGG GTRKQDCVLL 150
    ASEGTQVMRN GDSRAPSEAE SFALEVQDHV FQIPAPDYLQ HWGPAGDNVD 200
    HNEKDCVFKN HTEDESLEGI QPPVGEHGLN TPFSVRRSWD SLNEDVETEV 250
    LSICFNEKGP VHAMPVVDSG NRQEDTHGSD GDGDGEIVDE DAAVAEALAA 300
    LEAATAGEDL DETD 314
    Length:314
    Mass (Da):33,742
    Last modified:March 1, 2003 - v1
    Checksum:i65A8FEBD0F1B08EA
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti39 – 391D → E.
    Corresponds to variant rs6852908 [ dbSNP | Ensembl ].
    VAR_050770
    Natural varianti151 – 1511A → T.
    Corresponds to variant rs2973275 [ dbSNP | Ensembl ].
    VAR_032118
    Natural varianti274 – 2741E → G.1 Publication
    Corresponds to variant rs3733500 [ dbSNP | Ensembl ].
    VAR_032119

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001879 mRNA. Translation: BAA91958.1.
    BC037906 mRNA. Translation: AAH37906.1.
    CCDSiCCDS3442.1.
    RefSeqiNP_001098099.1. NM_001104629.1.
    NP_060772.2. NM_018302.2.
    UniGeneiHs.107527.

    Genome annotation databases

    EnsembliENST00000284437; ENSP00000284437; ENSG00000154274.
    ENST00000381980; ENSP00000371408; ENSG00000154274.
    GeneIDi55286.
    KEGGihsa:55286.
    UCSCiuc003gsw.4. human.

    Polymorphism databases

    DMDMi74728286.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK001879 mRNA. Translation: BAA91958.1 .
    BC037906 mRNA. Translation: AAH37906.1 .
    CCDSi CCDS3442.1.
    RefSeqi NP_001098099.1. NM_001104629.1.
    NP_060772.2. NM_018302.2.
    UniGenei Hs.107527.

    3D structure databases

    ProteinModelPortali Q8IY42.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000284437.

    PTM databases

    PhosphoSitei Q8IY42.

    Polymorphism databases

    DMDMi 74728286.

    Proteomic databases

    PaxDbi Q8IY42.
    PRIDEi Q8IY42.

    Protocols and materials databases

    DNASUi 55286.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000284437 ; ENSP00000284437 ; ENSG00000154274 .
    ENST00000381980 ; ENSP00000371408 ; ENSG00000154274 .
    GeneIDi 55286.
    KEGGi hsa:55286.
    UCSCi uc003gsw.4. human.

    Organism-specific databases

    CTDi 55286.
    GeneCardsi GC04P037455.
    HGNCi HGNC:25618. C4orf19.
    HPAi HPA043458.
    neXtProti NX_Q8IY42.
    PharmGKBi PA144596500.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG44497.
    HOGENOMi HOG000111464.
    HOVERGENi HBG099521.
    InParanoidi Q8IY42.
    OMAi QIPAPDY.
    OrthoDBi EOG7B31NT.
    PhylomeDBi Q8IY42.
    TreeFami TF337421.

    Miscellaneous databases

    GenomeRNAii 55286.
    NextBioi 59452.

    Gene expression databases

    ArrayExpressi Q8IY42.
    Bgeei Q8IY42.
    CleanExi HS_C4orf19.
    Genevestigatori Q8IY42.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT GLY-274.
      Tissue: Placenta.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiCD019_HUMAN
    AccessioniPrimary (citable) accession number: Q8IY42
    Secondary accession number(s): Q9NV03
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3