##gff-version 3
Q8IY37	UniProtKB	Chain	1	1157	.	.	.	ID=PRO_0000055172;Note=Probable ATP-dependent RNA helicase DHX37	
Q8IY37	UniProtKB	Domain	262	429	.	.	.	Note=Helicase ATP-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00541	
Q8IY37	UniProtKB	Domain	459	716	.	.	.	Note=Helicase C-terminal;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00542	
Q8IY37	UniProtKB	Region	1	77	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Region	116	225	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Region	494	523	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Region	542	584	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Motif	372	375	.	.	.	Note=DEAH box	
Q8IY37	UniProtKB	Compositional bias	161	185	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Compositional bias	198	225	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Compositional bias	495	518	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Compositional bias	550	573	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY37	UniProtKB	Binding site	275	282	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00541	
Q8IY37	UniProtKB	Natural variant	93	93	.	.	.	ID=VAR_083628;Note=In NEDBAVC%3B uncertain significance. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs575837056,PMID:31256877	
Q8IY37	UniProtKB	Natural variant	96	96	.	.	.	ID=VAR_061826;Note=M->I;Dbxref=dbSNP:rs11558556	
Q8IY37	UniProtKB	Natural variant	167	167	.	.	.	ID=VAR_083629;Note=In NEDBAVC%3B uncertain significance%3B requires 2 nucleotide substitutions. E->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=PMID:31256877	
Q8IY37	UniProtKB	Natural variant	304	304	.	.	.	ID=VAR_083630;Note=In SRXY11. T->M;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:31287541,ECO:0000269|PubMed:31337883;Dbxref=dbSNP:rs1954619788,PMID:31287541,PMID:31337883	
Q8IY37	UniProtKB	Natural variant	308	308	.	.	.	ID=VAR_083631;Note=In SRXY11. R->Q;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:31287541,ECO:0000269|PubMed:31337883;Dbxref=dbSNP:rs1384892917,PMID:31287541,PMID:31337883	
Q8IY37	UniProtKB	Natural variant	334	334	.	.	.	ID=VAR_083632;Note=In SRXY11%3B uncertain significance. R->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31337883;Dbxref=PMID:31337883	
Q8IY37	UniProtKB	Natural variant	334	334	.	.	.	ID=VAR_083633;Note=In SRXY11%3B uncertain significance. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31337883;Dbxref=PMID:31337883	
Q8IY37	UniProtKB	Natural variant	382	382	.	.	.	ID=VAR_083634;Note=In NEDBAVC%3B uncertain significance. D->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs1424699115,PMID:31256877	
Q8IY37	UniProtKB	Natural variant	419	419	.	.	.	ID=VAR_083635;Note=In NEDBAVC%3B uncertain significance. N->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:26539891,ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs1060499737,PMID:26539891,PMID:31256877	
Q8IY37	UniProtKB	Natural variant	458	458	.	.	.	ID=VAR_052185;Note=R->Q;Dbxref=dbSNP:rs11057939	
Q8IY37	UniProtKB	Natural variant	467	467	.	.	.	ID=VAR_083636;Note=In NEDBAVC%3B uncertain significance. L->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs149331610,PMID:31256877	
Q8IY37	UniProtKB	Natural variant	487	487	.	.	.	ID=VAR_083637;Note=In NEDBAVC%3B uncertain significance. R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26539891;Dbxref=dbSNP:rs779613772,PMID:26539891	
Q8IY37	UniProtKB	Natural variant	508	508	.	.	.	ID=VAR_052186;Note=K->N;Dbxref=dbSNP:rs35165507	
Q8IY37	UniProtKB	Natural variant	595	595	.	.	.	ID=VAR_083638;Note=In SRXY11. S->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31287541;Dbxref=dbSNP:rs1954346640,PMID:31287541	
Q8IY37	UniProtKB	Natural variant	626	626	.	.	.	ID=VAR_083639;Note=In SRXY11%3B uncertain significance. S->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31337883;Dbxref=PMID:31337883	
Q8IY37	UniProtKB	Natural variant	674	674	.	.	.	ID=VAR_083640;Note=In SRXY11. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31337883;Dbxref=dbSNP:rs1954336215,PMID:31337883	
Q8IY37	UniProtKB	Natural variant	674	674	.	.	.	ID=VAR_083641;Note=In SRXY11. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31287541;Dbxref=dbSNP:rs1954336272,PMID:31287541	
Q8IY37	UniProtKB	Natural variant	717	717	.	.	.	ID=VAR_052187;Note=V->I;Dbxref=dbSNP:rs35016004	
Q8IY37	UniProtKB	Natural variant	731	731	.	.	.	ID=VAR_083642;Note=In NEDBAVC%3B uncertain significance. V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs754186165,PMID:31256877	
Q8IY37	UniProtKB	Natural variant	869	869	.	.	.	ID=VAR_052188;Note=S->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs4516060,PMID:15489334	
Q8IY37	UniProtKB	Natural variant	1030	1030	.	.	.	ID=VAR_083643;Note=In SRXY11%3B uncertain significance. G->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31337883;Dbxref=dbSNP:rs754141645,PMID:31337883	
Q8IY37	UniProtKB	Natural variant	1081	1081	.	.	.	ID=VAR_052189;Note=R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs4447263,PMID:15489334	
Q8IY37	UniProtKB	Natural variant	1094	1094	.	.	.	ID=VAR_083644;Note=In NEDBAVC%3B uncertain significance. T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31256877;Dbxref=dbSNP:rs1277857720,PMID:31256877	
Q8IY37	UniProtKB	Mutagenesis	282	282	.	.	.	Note=Impairs the catalytic activity of the helicase. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30582406;Dbxref=PMID:30582406	
Q8IY37	UniProtKB	Sequence conflict	174	174	.	.	.	Note=E->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8IY37	UniProtKB	Sequence conflict	898	898	.	.	.	Note=A->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8IY37	UniProtKB	Sequence conflict	1130	1157	.	.	.	Note=YLLAEYCEWLPQAMHPDIEKAWPPTTVH->CEFDQGQGVGVDRMGSLRQGLCALCTVSPGLAEGSGPTAAGQLFAT;Ontology_term=ECO:0000305;evidence=ECO:0000305