##gff-version 3
Q8IY18	UniProtKB	Chain	1	1101	.	.	.	ID=PRO_0000270951;Note=Structural maintenance of chromosomes protein 5	
Q8IY18	UniProtKB	Region	1	43	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY18	UniProtKB	Region	446	646	.	.	.	Note=Flexible hinge	
Q8IY18	UniProtKB	Coiled coil	207	445	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8IY18	UniProtKB	Coiled coil	647	828	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8IY18	UniProtKB	Coiled coil	888	927	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8IY18	UniProtKB	Compositional bias	1	16	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IY18	UniProtKB	Binding site	80	87	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8IY18	UniProtKB	Modified residue	25	25	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q8IY18	UniProtKB	Modified residue	35	35	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:18669648,ECO:0007744|PubMed:19690332,ECO:0007744|PubMed:23186163,ECO:0007744|PubMed:24275569;Dbxref=PMID:18669648,PMID:19690332,PMID:23186163,PMID:24275569	
Q8IY18	UniProtKB	Natural variant	306	306	.	.	.	ID=VAR_029824;Note=V->I;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11408570,ECO:0000269|PubMed:15489334,ECO:0000269|PubMed:9628581;Dbxref=dbSNP:rs1180116,PMID:11408570,PMID:15489334,PMID:9628581	
Q8IY18	UniProtKB	Natural variant	308	308	.	.	.	ID=VAR_029825;Note=C->R;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11408570,ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs1180117,PMID:11408570,PMID:15489334	
Q8IY18	UniProtKB	Natural variant	372	372	.	.	.	ID=VAR_087971;Note=In ATELS2%3B loss-of-function variant%3B unable to rescue microcephaly and aberrant craniofacial patterning in zebrafish lacking SMC5%3B does not relocalize efficiently to sites of laser irradiation-induced DNA damage%3B loss of interaction with SLF2 and NSMCE2%3B severely decreased interaction with SMC6. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36333305;Dbxref=PMID:36333305	
Q8IY18	UniProtKB	Natural variant	425	1101	.	.	.	ID=VAR_087972;Note=In ATELS2%3B loss-of-function variant%3B unable to rescue microcephaly and aberrant craniofacial patterning in zebrafish lacking SMC5%3B loss of interaction with SLF2%2C SMC6 and NSMCE2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36333305;Dbxref=PMID:36333305	
Q8IY18	UniProtKB	Natural variant	682	682	.	.	.	ID=VAR_061869;Note=H->R;Dbxref=dbSNP:rs11142365	
Q8IY18	UniProtKB	Natural variant	990	990	.	.	.	ID=VAR_087973;Note=In ATELS2%3B loss-of-function variant%3B unable to rescue microcephaly and aberrant craniofacial patterning in zebrafish lacking SMC5%3B does not relocalize efficiently to sites of laser irradiation-induced DNA damage%3B no effect on interaction with SLF2%2C SMC6 and NSMCE2. H->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36333305;Dbxref=PMID:36333305