Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Dihydropyrimidinase-like 3

Gene

DPYSL3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Dihydropyrimidinase-like 3Imported
Gene namesi
Name:DPYSL3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27473.

PTM / Processingi

Proteomic databases

PaxDbiQ8IXW6.
PeptideAtlasiQ8IXW6.
PRIDEiQ8IXW6.

Expressioni

Gene expression databases

GenevisibleiQ8IXW6. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
DPYSL2Q165553EBI-10262612,EBI-1104711

Protein-protein interaction databases

IntActiQ8IXW6. 1 interaction.
STRINGi9606.ENSP00000343690.

Structurei

3D structure databases

ProteinModelPortaliQ8IXW6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini64 – 452389Amidohydro-relInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2584. Eukaryota.
COG0044. LUCA.
HOVERGENiHBG000806.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
InterProiIPR006680. Amidohydro-rel.
IPR030628. DRP3.
IPR011778. Hydantoinase/dihydroPyrase.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PANTHERiPTHR11647:SF57. PTHR11647:SF57. 1 hit.
PfamiPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR02033. D-hydantoinase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IXW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYQGKKNIP RITSDRLLIK GGRIVNDDQS FYADIYMEDG LIKQIGDNLI
60 70 80 90 100
VPGGVKTIEA NGKMVIPGGI DVHTHYQMPY KGMTTVDDFF QGTKAALAGG
110 120 130 140 150
TTMIIDHVVP EPESSLTEAY EKWREWADGK SCCDYALHVD ITHWNDSVKQ
160 170 180 190 200
EVQNLIKDKG VNSFMVYMAY KDLYQVSNTE LYEIFTCLGE LGAIAQVHAE
210 220 230 240 250
NGDIIAQEQT RMLEMGITGP EGHVLSRPEE LEAEAVFRAI TIASQTNCPL
260 270 280 290 300
YVTKVMSKSA ADLISQARKK GNVVFGEPIT ASLGIDGTHY WSKNWAKAAA
310 320 330 340 350
FVTSPPLSPD PTTPDYINSL LASGDLQLSG SAHCTFSTAQ KAIGKDNFTA
360 370 380 390 400
IPEGTNGVEE RMSVIWDKAV ATGKMDENQF VAVTSTNAAK IFNLYPRKGR
410 420 430 440 450
ISVGSDSDLV IWDPDAVKIV SAKNHQSAAE YNIFEGMELR GAPLVVICQG
460 470 480 490 500
KIMLEDGNLH VTQGAGRFIP CSPFSDYVYK RIKARRKMAD LHAVPRGMYD
510 520 530 540 550
GPVFDLTTTP KGGTPAGSAR GSPTRPNPPV RNLHQSGFSL SGTQVDEGVR
560 570
SASKRIVAPP GGRSNITSLS
Length:570
Mass (Da):61,979
Last modified:March 1, 2003 - v1
Checksum:i0CADE2F70CAF4F0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039006 mRNA. Translation: AAH39006.1.
RefSeqiNP_001378.1. NM_001387.2.
UniGeneiHs.519659.

Genome annotation databases

GeneIDi1809.
KEGGihsa:1809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039006 mRNA. Translation: AAH39006.1.
RefSeqiNP_001378.1. NM_001387.2.
UniGeneiHs.519659.

3D structure databases

ProteinModelPortaliQ8IXW6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IXW6. 1 interaction.
STRINGi9606.ENSP00000343690.

Proteomic databases

PaxDbiQ8IXW6.
PeptideAtlasiQ8IXW6.
PRIDEiQ8IXW6.

Protocols and materials databases

DNASUi1809.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1809.
KEGGihsa:1809.

Organism-specific databases

CTDi1809.
PharmGKBiPA27473.

Phylogenomic databases

eggNOGiKOG2584. Eukaryota.
COG0044. LUCA.
HOVERGENiHBG000806.

Miscellaneous databases

ChiTaRSiDPYSL3. human.
GenomeRNAii1809.

Gene expression databases

GenevisibleiQ8IXW6. HS.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
InterProiIPR006680. Amidohydro-rel.
IPR030628. DRP3.
IPR011778. Hydantoinase/dihydroPyrase.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PANTHERiPTHR11647:SF57. PTHR11647:SF57. 1 hit.
PfamiPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR02033. D-hydantoinase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IXW6_HUMAN
AccessioniPrimary (citable) accession number: Q8IXW6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.