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Protein

Uncharacterized protein C12orf56

Gene

C12orf56

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C12orf56
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000185306.12
HGNCiHGNC:26967 C12orf56
neXtProtiNX_Q8IXR9

Pathology & Biotechi

Organism-specific databases

DisGeNETi115749
OpenTargetsiENSG00000185306
PharmGKBiPA143485385

Polymorphism and mutation databases

BioMutaiC12orf56
DMDMi449081294

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003209261 – 622Uncharacterized protein C12orf56Add BLAST622

Proteomic databases

MaxQBiQ8IXR9
PaxDbiQ8IXR9
PeptideAtlasiQ8IXR9
PRIDEiQ8IXR9
ProteomicsDBi71052
71053 [Q8IXR9-2]

PTM databases

iPTMnetiQ8IXR9
PhosphoSitePlusiQ8IXR9

Expressioni

Gene expression databases

BgeeiENSG00000185306
CleanExiHS_C12orf56
ExpressionAtlasiQ8IXR9 baseline and differential
GenevisibleiQ8IXR9 HS

Organism-specific databases

HPAiHPA056986

Interactioni

Protein-protein interaction databases

BioGridi125452, 1 interactor
STRINGi9606.ENSP00000329698

Structurei

3D structure databases

ProteinModelPortaliQ8IXR9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IXM6 Eukaryota
ENOG4111GBY LUCA
GeneTreeiENSGT00390000018424
HOGENOMiHOG000057286
HOVERGENiHBG107709
InParanoidiQ8IXR9
OMAiELHLYVI
OrthoDBiEOG091G04F9
TreeFamiTF331535

Family and domain databases

InterProiView protein in InterPro
IPR027878 DUF4551
PANTHERiPTHR35354 PTHR35354, 1 hit
PfamiView protein in Pfam
PF15087 DUF4551, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8IXR9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASPLPSGFP ARRNSRLDVF LRRHLPPEVY DAVRAYEPCI VVSNSENHIL
60 70 80 90 100
KYVVLSDRLV YLTENPPKSI RRVVALRDVV AIDLIDDYPE FLSSPDREIS
110 120 130 140 150
QHIRIIYSST VLKKECKKSN SVRKFLFPFH HTKANNKKVK EEKNGLAFWR
160 170 180 190 200
SKESRSLKES PLRDQQESST PSKDSTLCPR PGLKKLSLHG QGAFRPLPSP
210 220 230 240 250
SRRSSQSAPT TGKAVSEPSC TTNTKEPQGL PDHNSISEIP FKCNGNGNEF
260 270 280 290 300
YLGNSLLDSP SQSNSNLEKK ESELHLYVIS TTSSIFLHLK SSWNNYIIKA
310 320 330 340 350
TLLQDPFYAS EFSPAIGSQK PYRSEEKIKH FSQLKSELFL KDNSLRRILS
360 370 380 390 400
LLMELKVAAQ KNFILKRLFW KTSDLFYFIV NKLHEYLPES RDKNALQNQS
410 420 430 440 450
QRVDELVACI EIIQTLVLMF RETETESSRL NTLAAKKGAL FNLLVILISE
460 470 480 490 500
PQIPKSCPVF DIQLVADSAL VRMSFDAELQ KLILEYTNTA TALLYEILLV
510 520 530 540 550
FQQGNLGLGS TKFAISWIMS FLQSCPPIIT FVASIVKQVV RGLSASFQLL
560 570 580 590 600
SPCQAVLLYQ QFYILKSCLR HSRTLAEYIR NNYREEFRYF IHMPALQKRL
610 620
PLCYPITQPT IQLFHEVLKL VE
Length:622
Mass (Da):71,046
Last modified:February 6, 2013 - v3
Checksum:i35E0DC70E2A6A354
GO
Isoform 2 (identifier: Q8IXR9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     164-323: Missing.

Note: No experimental confirmation available.
Show »
Length:462
Mass (Da):53,562
Checksum:i725527381B2D26AF
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_031745164 – 323Missing in isoform 2. 1 PublicationAdd BLAST160

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012158 Genomic DNA No translation available.
AC135279 Genomic DNA No translation available.
BC039369 mRNA Translation: AAH39369.1
CCDSiCCDS44935.1 [Q8IXR9-2]
CCDS61182.1 [Q8IXR9-1]
RefSeqiNP_001093146.1, NM_001099676.2 [Q8IXR9-2]
NP_001164104.1, NM_001170633.1 [Q8IXR9-1]
UniGeneiHs.535190

Genome annotation databases

EnsembliENST00000333722; ENSP00000329698; ENSG00000185306 [Q8IXR9-2]
ENST00000543942; ENSP00000446101; ENSG00000185306 [Q8IXR9-1]
GeneIDi115749
KEGGihsa:115749
UCSCiuc001ssa.5 human [Q8IXR9-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiCL056_HUMAN
AccessioniPrimary (citable) accession number: Q8IXR9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 6, 2013
Last modified: June 20, 2018
This is version 90 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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