Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8IXR9

- CL056_HUMAN

UniProt

Q8IXR9 - CL056_HUMAN

Protein

Uncharacterized protein C12orf56

Gene

C12orf56

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 3 (06 Feb 2013)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C12orf56
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:26967. C12orf56.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA143485385.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 622622Uncharacterized protein C12orf56PRO_0000320926Add
    BLAST

    Proteomic databases

    PaxDbiQ8IXR9.
    PRIDEiQ8IXR9.

    PTM databases

    PhosphoSiteiQ8IXR9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8IXR9.
    BgeeiQ8IXR9.
    CleanExiHS_C12orf56.
    GenevestigatoriQ8IXR9.

    Organism-specific databases

    HPAiHPA056986.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000329698.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IXR9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG47866.
    HOGENOMiHOG000057286.
    HOVERGENiHBG107709.
    OMAiNEFYLGN.
    TreeFamiTF331535.

    Family and domain databases

    InterProiIPR027878. DUF4551.
    [Graphical view]
    PfamiPF15087. DUF4551. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8IXR9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MASPLPSGFP ARRNSRLDVF LRRHLPPEVY DAVRAYEPCI VVSNSENHIL    50
    KYVVLSDRLV YLTENPPKSI RRVVALRDVV AIDLIDDYPE FLSSPDREIS 100
    QHIRIIYSST VLKKECKKSN SVRKFLFPFH HTKANNKKVK EEKNGLAFWR 150
    SKESRSLKES PLRDQQESST PSKDSTLCPR PGLKKLSLHG QGAFRPLPSP 200
    SRRSSQSAPT TGKAVSEPSC TTNTKEPQGL PDHNSISEIP FKCNGNGNEF 250
    YLGNSLLDSP SQSNSNLEKK ESELHLYVIS TTSSIFLHLK SSWNNYIIKA 300
    TLLQDPFYAS EFSPAIGSQK PYRSEEKIKH FSQLKSELFL KDNSLRRILS 350
    LLMELKVAAQ KNFILKRLFW KTSDLFYFIV NKLHEYLPES RDKNALQNQS 400
    QRVDELVACI EIIQTLVLMF RETETESSRL NTLAAKKGAL FNLLVILISE 450
    PQIPKSCPVF DIQLVADSAL VRMSFDAELQ KLILEYTNTA TALLYEILLV 500
    FQQGNLGLGS TKFAISWIMS FLQSCPPIIT FVASIVKQVV RGLSASFQLL 550
    SPCQAVLLYQ QFYILKSCLR HSRTLAEYIR NNYREEFRYF IHMPALQKRL 600
    PLCYPITQPT IQLFHEVLKL VE 622
    Length:622
    Mass (Da):71,046
    Last modified:February 6, 2013 - v3
    Checksum:i35E0DC70E2A6A354
    GO
    Isoform 2 (identifier: Q8IXR9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         164-323: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:462
    Mass (Da):53,562
    Checksum:i725527381B2D26AF
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei164 – 323160Missing in isoform 2. 1 PublicationVSP_031745Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012158 Genomic DNA. No translation available.
    AC135279 Genomic DNA. No translation available.
    BC039369 mRNA. Translation: AAH39369.1.
    CCDSiCCDS44935.1. [Q8IXR9-2]
    CCDS61182.1. [Q8IXR9-1]
    RefSeqiNP_001093146.1. NM_001099676.2. [Q8IXR9-2]
    NP_001164104.1. NM_001170633.1. [Q8IXR9-1]
    UniGeneiHs.535190.

    Genome annotation databases

    EnsembliENST00000333722; ENSP00000329698; ENSG00000185306. [Q8IXR9-2]
    ENST00000543942; ENSP00000446101; ENSG00000185306. [Q8IXR9-1]
    GeneIDi115749.
    KEGGihsa:115749.
    UCSCiuc001ssa.4. human. [Q8IXR9-2]

    Polymorphism databases

    DMDMi449081294.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012158 Genomic DNA. No translation available.
    AC135279 Genomic DNA. No translation available.
    BC039369 mRNA. Translation: AAH39369.1 .
    CCDSi CCDS44935.1. [Q8IXR9-2 ]
    CCDS61182.1. [Q8IXR9-1 ]
    RefSeqi NP_001093146.1. NM_001099676.2. [Q8IXR9-2 ]
    NP_001164104.1. NM_001170633.1. [Q8IXR9-1 ]
    UniGenei Hs.535190.

    3D structure databases

    ProteinModelPortali Q8IXR9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000329698.

    PTM databases

    PhosphoSitei Q8IXR9.

    Polymorphism databases

    DMDMi 449081294.

    Proteomic databases

    PaxDbi Q8IXR9.
    PRIDEi Q8IXR9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000333722 ; ENSP00000329698 ; ENSG00000185306 . [Q8IXR9-2 ]
    ENST00000543942 ; ENSP00000446101 ; ENSG00000185306 . [Q8IXR9-1 ]
    GeneIDi 115749.
    KEGGi hsa:115749.
    UCSCi uc001ssa.4. human. [Q8IXR9-2 ]

    Organism-specific databases

    CTDi 115749.
    GeneCardsi GC12M064661.
    HGNCi HGNC:26967. C12orf56.
    HPAi HPA056986.
    neXtProti NX_Q8IXR9.
    PharmGKBi PA143485385.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG47866.
    HOGENOMi HOG000057286.
    HOVERGENi HBG107709.
    OMAi NEFYLGN.
    TreeFami TF331535.

    Miscellaneous databases

    GenomeRNAii 115749.
    NextBioi 79666.

    Gene expression databases

    ArrayExpressi Q8IXR9.
    Bgeei Q8IXR9.
    CleanExi HS_C12orf56.
    Genevestigatori Q8IXR9.

    Family and domain databases

    InterProi IPR027878. DUF4551.
    [Graphical view ]
    Pfami PF15087. DUF4551. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 19-622 (ISOFORM 2).
      Tissue: Testis.

    Entry informationi

    Entry nameiCL056_HUMAN
    AccessioniPrimary (citable) accession number: Q8IXR9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: February 6, 2013
    Last modified: October 1, 2014
    This is version 67 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM

    External Data

    Dasty 3