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Q8IX12 (CCAR1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cell division cycle and apoptosis regulator protein 1
Alternative name(s):
Cell cycle and apoptosis regulatory protein 1
Short name=CARP-1
Death inducer with SAP domain
Gene names
Name:CCAR1
Synonyms:CARP1, DIS
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1150 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation By similarity. May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. Ref.1

Subunit structure

Directly interacts with CALCOCO1, ESR1, NR3C1 and TP53 By similarity. Ref.8

Subcellular location

Cytoplasmperinuclear region Ref.1.

Tissue specificity

Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. Ref.1

Sequence similarities

Contains 1 SAP domain.

Sequence caution

The sequence AAH26036.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

The sequence AAI08683.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

The sequence BAA91354.1 differs from that shown. Reason: Erroneous initiation.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

TRIM63Q969Q12EBI-356265,EBI-5661333
WWTR1Q9GZV52EBI-356265,EBI-747743
Wwtr1Q9EPK55EBI-356265,EBI-1211920From a different organism.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q8IX12-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q8IX12-2)

The sequence of this isoform differs from the canonical sequence as follows:
     83-97: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11501150Cell division cycle and apoptosis regulator protein 1
PRO_0000233148

Regions

Domain636 – 67035SAP
Coiled coil594 – 61825 Potential
Coiled coil1033 – 111482 Potential
Compositional bias73 – 797Poly-Ala
Compositional bias293 – 36169Arg-rich
Compositional bias673 – 889217Glu-rich

Amino acid modifications

Modified residue6851Phosphoserine Ref.10
Modified residue6971Phosphoserine Ref.10
Modified residue8611Phosphothreonine Ref.10 Ref.12
Cross-link637Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) Ref.9

Natural variations

Alternative sequence83 – 9715Missing in isoform 2.
VSP_037736
Natural variant5881T → I.
Corresponds to variant rs1782338 [ dbSNP | Ensembl ].
VAR_058330
Natural variant6071E → K in a colorectal cancer sample; somatic mutation. Ref.13
VAR_035497
Natural variant6811E → G.
Corresponds to variant rs1060145 [ dbSNP | Ensembl ].
VAR_058331
Natural variant7471M → V.
Corresponds to variant rs11542602 [ dbSNP | Ensembl ].
VAR_058332

Experimental info

Sequence conflict2961D → Y in BAA91354. Ref.3
Sequence conflict3051N → S in BAG60310. Ref.3
Sequence conflict4921K → E in BAA91847. Ref.3
Sequence conflict6181D → Y in AAH15475. Ref.6
Sequence conflict6501S → G in AAO17319. Ref.2
Sequence conflict6501S → G in BAA91700. Ref.3
Sequence conflict7231L → S in BAF85338. Ref.3
Sequence conflict801 – 8033EKD → KKK in AAH89420. Ref.6
Sequence conflict816 – 8183EER → KKK in AAH15475. Ref.6
Sequence conflict8531D → G Ref.1
Sequence conflict8531D → G Ref.2
Sequence conflict8531D → G in BAA91700. Ref.3
Sequence conflict11041N → S Ref.1
Sequence conflict11041N → S Ref.2
Sequence conflict11041N → S in BAA91700. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 2, 2006. Version 2.
Checksum: 30618DCC8097F552

FASTA1,150132,821
        10         20         30         40         50         60 
MAQFGGQKNP PWATQFTATA VSQPAALGVQ QPSLLGASPT IYTQQTALAA AGLTTQTPAN 

        70         80         90        100        110        120 
YQLTQTAALQ QQAAAAAAAL QQQYSQPQQA LYSVQQQLQQ PQQTLLTQPA VALPTSLSLS 

       130        140        150        160        170        180 
TPQPTAQITV SYPTPRSSQQ QTQPQKQRVF TGVVTKLHDT FGFVDEDVFF QLSAVKGKTP 

       190        200        210        220        230        240 
QVGDRVLVEA TYNPNMPFKW NAQRIQTLPN QNQSQTQPLL KTPPAVLQPI APQTTFGVQT 

       250        260        270        280        290        300 
QPQPQSLLQA QISAASITPL LQTQPQPLLQ QPQQKAGLLQ PPVRIVSQPQ PARRLDPPSR 

       310        320        330        340        350        360 
FSGRNDRGDQ VPNRKDDRSR ERERERRRSR ERSPQRKRSR ERSPRRERER SPRRVRRVVP 

       370        380        390        400        410        420 
RYTVQFSKFS LDCPSCDMME LRRRYQNLYI PSDFFDAQFT WVDAFPLSRP FQLGNYCNFY 

       430        440        450        460        470        480 
VMHREVESLE KNMAILDPPD ADHLYSAKVM LMASPSMEDL YHKSCALAED PQELRDGFQH 

       490        500        510        520        530        540 
PARLVKFLVG MKGKDEAMAI GGHWSPSLDG PDPEKDPSVL IKTAIRCCKA LTGIDLSVCT 

       550        560        570        580        590        600 
QWYRFAEIRY HRPEETHKGR TVPAHVETVV LFFPDVWHCL PTRSEWETLS RGYKQQLVEK 

       610        620        630        640        650        660 
LQGERKEADG EQDEEEKDDG EAKEISTPTH WSKLDPKTMK VNDLRKELES RALSSKGLKS 

       670        680        690        700        710        720 
QLIARLTKQL KVEEQKEEQK ELEKSEKEED EDDDRKSEDD KEEEERKRQE EIERQRRERR 

       730        740        750        760        770        780 
YILPDEPAII VHPNWAAKSG KFDCSIMSLS VLLDYRLEDN KEHSFEVSLF AELFNEMLQR 

       790        800        810        820        830        840 
DFGVRIYKSL LSLPEKEDKK EKDKKSKKDE RKDKKEERDD ETDEPKPKRR KSGDDKDKKE 

       850        860        870        880        890        900 
DRDERKKEDK RKDDSKDDDE TEEDNNQDEY DPMEAEEAED EEDDRDEEEM TKRDDKRDIN 

       910        920        930        940        950        960 
RYCKERPSKD KEKEKTQMIT INRDLLMAFV YFDQSHCGYL LEKDLEEILY TLGLHLSRAQ 

       970        980        990       1000       1010       1020 
VKKLLNKVVL RESCFYRKLT DTSKDEENHE ESESLQEDML GNRLLLPTPT VKQESKDVEE 

      1030       1040       1050       1060       1070       1080 
NVGLIVYNGA MVDVGSLLQK LEKSEKVRAE VEQKLQLLEE KTDEDEKTIL NLENSNKSLS 

      1090       1100       1110       1120       1130       1140 
GELREVKKDL SQLQENLKIS ENMNLQFENQ MNKTIRNLST VMDEIHTVLK KDNVKNEDKD 

      1150 
QKSKENGASV 

« Hide

Isoform 2 [UniParc].

Checksum: 1F36D655EC82941E
Show »

FASTA1,135131,043

References

« Hide 'large scale' references
[1]"Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437."
Rishi A.K., Zhang L., Boyanapalli M., Wali A., Mohammad R.M., Yu Y., Fontana J.A., Hatfield J.S., Dawson M.I., Majumdar A.P.N., Reichert U.
J. Biol. Chem. 278:33422-33435(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
[2]"TAZ binding partners identified by mass spectrometry."
Tian Y., Li D., Benjamin T.
Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[3]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1058 (ISOFORM 2).
Tissue: Hepatoma, Lung, Placenta, Teratocarcinoma and Thymus.
[4]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-818 (ISOFORM 1).
Tissue: Cerebellum, Lung, Lymph, Muscle and Skin.
[7]"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.
Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic kidney.
[8]"CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes."
Kim J.H., Yang C.K., Heo K., Roeder R.G., An W., Stallcup M.R.
Mol. Cell 31:510-519(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH CALCOCO1.
[9]"Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells."
Tan F., Lu L., Cai Y., Wang J., Xie Y., Wang L., Gong Y., Xu B.-E., Wu J., Luo Y., Qiang B., Yuan J., Sun X., Peng X.
Proteomics 8:2885-2896(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-637.
Tissue: Cervix carcinoma.
[10]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-685; SER-697 AND THR-861, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[11]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-861, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANT [LARGE SCALE ANALYSIS] LYS-607.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY249140 mRNA. Translation: AAP82002.1.
AF465616 mRNA. Translation: AAO17319.1.
AK000741 mRNA. Translation: BAA91354.1. Different initiation.
AK001452 mRNA. Translation: BAA91700.1.
AK001701 mRNA. Translation: BAA91847.1.
AK023438 mRNA. Translation: BAB14574.1.
AK298004 mRNA. Translation: BAG60310.1.
AK299307 mRNA. Translation: BAG61320.1.
AK292649 mRNA. Translation: BAF85338.1.
AL513534, AL391539 Genomic DNA. Translation: CAH70221.1.
AL391539, AL513534 Genomic DNA. Translation: CAH73835.1.
CH471083 Genomic DNA. Translation: EAW54302.1.
BC015475 mRNA. Translation: AAH15475.1.
BC026036 mRNA. Translation: AAH26036.1. Sequence problems.
BC089420 mRNA. Translation: AAH89420.1.
BC130626 mRNA. Translation: AAI30627.1.
BC132725 mRNA. Translation: AAI32726.1.
BC108682 mRNA. Translation: AAI08683.1. Sequence problems.
RefSeqNP_001269888.1. NM_001282959.1.
NP_001269889.1. NM_001282960.1.
NP_060707.2. NM_018237.3.
UniGeneHs.49853.

3D structure databases

ProteinModelPortalQ8IX12.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid120867. 17 interactions.
DIPDIP-27607N.
IntActQ8IX12. 22 interactions.
MINTMINT-1139760.

PTM databases

PhosphoSiteQ8IX12.

Polymorphism databases

DMDM94707499.

Proteomic databases

PaxDbQ8IX12.
PeptideAtlasQ8IX12.
PRIDEQ8IX12.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000265872; ENSP00000265872; ENSG00000060339. [Q8IX12-1]
ENST00000535016; ENSP00000441820; ENSG00000060339. [Q8IX12-2]
ENST00000539539; ENSP00000439252; ENSG00000060339.
ENST00000543719; ENSP00000445254; ENSG00000060339. [Q8IX12-2]
GeneID55749.
KEGGhsa:55749.
UCSCuc001jom.1. human. [Q8IX12-1]
uc010qiz.1. human. [Q8IX12-2]

Organism-specific databases

CTD55749.
GeneCardsGC10P070480.
HGNCHGNC:24236. CCAR1.
HPAHPA007856.
HPA048513.
MIM612569. gene.
neXtProtNX_Q8IX12.
PharmGKBPA134920227.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG313311.
HOVERGENHBG079908.
InParanoidQ8IX12.
OMAELYHKSC.
OrthoDBEOG7CK365.
PhylomeDBQ8IX12.
TreeFamTF316387.

Enzyme and pathway databases

ReactomeREACT_71. Gene Expression.

Gene expression databases

ArrayExpressQ8IX12.
BgeeQ8IX12.
CleanExHS_CCAR1.
GenevestigatorQ8IX12.

Family and domain databases

Gene3D1.10.720.30. 1 hit.
2.40.50.140. 1 hit.
InterProIPR025224. DBC1/CARP1.
IPR025954. DBC1/CARP1_inactive_NUDIX_dom.
IPR012340. NA-bd_OB-fold.
IPR025223. S1-like_RNA-bd_dom.
IPR003034. SAP_dom.
[Graphical view]
PANTHERPTHR14304. PTHR14304. 1 hit.
PfamPF14443. DBC1. 1 hit.
PF14444. S1-like. 1 hit.
PF02037. SAP. 1 hit.
[Graphical view]
SMARTSM00513. SAP. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
PROSITEPS50800. SAP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSCCAR1. human.
GeneWikiCCAR1.
GenomeRNAi55749.
NextBio60733.
PROQ8IX12.
SOURCESearch...

Entry information

Entry nameCCAR1_HUMAN
AccessionPrimary (citable) accession number: Q8IX12
Secondary accession number(s): A0JLT7 expand/collapse secondary AC list , A1L4P7, A8K9D4, B4DNP8, B4DRK8, Q32NE3, Q5EBM3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: May 2, 2006
Last modified: April 16, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM