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Q8IX04

- UEVLD_HUMAN

UniProt

Q8IX04 - UEVLD_HUMAN

Protein

Ubiquitin-conjugating enzyme E2 variant 3

Gene

UEVLD

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 2 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    Possible negative regulator of polyubiquitination.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi191 – 21929NADBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. cellular protein modification process Source: InterPro
    3. protein transport Source: InterPro

    Keywords - Biological processi

    Ubl conjugation pathway

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin-conjugating enzyme E2 variant 3
    Short name:
    UEV-3
    Alternative name(s):
    EV and lactate/malate dehydrogenase domain-containing protein
    Gene namesi
    Name:UEVLDImported
    Synonyms:UEV3Imported
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:30866. UEVLD.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular vesicular exosome Source: UniProt

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA147357188.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 471471Ubiquitin-conjugating enzyme E2 variant 3PRO_0000278651Add
    BLAST

    Proteomic databases

    MaxQBiQ8IX04.
    PaxDbiQ8IX04.
    PRIDEiQ8IX04.

    PTM databases

    PhosphoSiteiQ8IX04.

    Expressioni

    Tissue specificityi

    Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.1 Publication

    Gene expression databases

    ArrayExpressiQ8IX04.
    BgeeiQ8IX04.
    CleanExiHS_UEVLD.
    GenevestigatoriQ8IX04.

    Organism-specific databases

    HPAiHPA047134.

    Interactioni

    Subunit structurei

    Homodimer.

    Protein-protein interaction databases

    BioGridi120580. 6 interactions.
    IntActiQ8IX04. 7 interactions.
    STRINGi9606.ENSP00000379500.

    Structurei

    Secondary structure

    1
    471
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi184 – 1885
    Helixi192 – 20413
    Beta strandi208 – 2136
    Helixi218 – 2203
    Helixi223 – 2297
    Beta strandi234 – 2385
    Helixi240 – 2434
    Beta strandi247 – 2515
    Helixi262 – 28322
    Turni284 – 2863
    Beta strandi288 – 2914
    Beta strandi293 – 2953
    Helixi296 – 30712
    Helixi311 – 3133
    Beta strandi314 – 3163
    Helixi320 – 33213
    Helixi339 – 3424
    Beta strandi343 – 3486
    Beta strandi350 – 3523
    Beta strandi354 – 3585
    Helixi366 – 37712
    Beta strandi380 – 3823
    Helixi387 – 40216
    Beta strandi407 – 4148
    Beta strandi426 – 4349
    Beta strandi437 – 4415
    Helixi450 – 46819

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2I6TX-ray2.10A/B171-471[»]
    3DL2X-ray2.10A/B171-471[»]
    ProteinModelPortaliQ8IX04.
    SMRiQ8IX04. Positions 8-143, 181-471.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8IX04.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 145144UEVPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.Curated
    In the C-terminal section; belongs to the LDH/MDH superfamily.Curated
    Contains 1 UEV (ubiquitin E2 variant) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0039.
    HOGENOMiHOG000213793.
    HOVERGENiHBG000462.
    InParanoidiQ8IX04.
    OMAiNIPIRLW.
    OrthoDBiEOG7JT6WH.
    PhylomeDBiQ8IX04.
    TreeFamiTF314963.

    Family and domain databases

    Gene3Di3.10.110.10. 1 hit.
    3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProiIPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR016040. NAD(P)-bd_dom.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    IPR008883. UEV_N.
    [Graphical view]
    PfamiPF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    PF05743. UEV. 1 hit.
    [Graphical view]
    PRINTSiPR00086. LLDHDRGNASE.
    SUPFAMiSSF54495. SSF54495. 1 hit.
    SSF56327. SSF56327. 1 hit.
    PROSITEiPS51322. UEV. 1 hit.
    [Graphical view]

    Sequences (7)i

    Sequence statusi: Complete.

    This entry describes 7 isoformsi produced by alternative splicing. Align

    Isoform 11 Publication (identifier: Q8IX04-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYVFKDSSQK    50
    DLLNFTGTIP VMYQGNTYNI PIRFWILDSH PFAPPICFLK PTANMGILVG 100
    KHVDAQGRIY LPYLQNWSHP KSVIVGLIKE MIAKFQEELP MYSLSSSDEA 150
    RQVDLLAYIA KITEGVSDTN SKSWANHENK TVNKITVVGG GELGIACTLA 200
    ISAKGIADRL VLLDLSEGTK GATMDLEIFN LPNVEISKDL SASAHSKVVI 250
    FTVNSLGSSQ SYLDVVQSNV DMFRALVPAL GHYSQHSVLL VASQPVEIMT 300
    YVTWKLSTFP ANRVIGIGCN LDSQRLQYII TNVLKAQTSG KEVWVIGEQG 350
    EDKVLTWSGQ EEVVSHTSQV QLSNRAMELL RVKGQRSWSV GLSVADMVDS 400
    IVNNKKKVHS VSALAKGYYD INSEVFLSLP CILGTNGVSE VIKTTLKEDT 450
    VTEKLQSSAS SIHSLQQQLK L 471
    Length:471
    Mass (Da):52,264
    Last modified:February 20, 2007 - v2
    Checksum:i2502659A566E7DDD
    GO
    Isoform 21 Publication (identifier: Q8IX04-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         376-379: AMEL → DIMI
         380-471: Missing.

    Show »
    Length:379
    Mass (Da):42,292
    Checksum:i100BCD1FA295FC60
    GO
    Isoform 31 Publication (identifier: Q8IX04-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         43-64: Missing.
         376-379: AMEL → DIMI
         380-471: Missing.

    Show »
    Length:357
    Mass (Da):39,778
    Checksum:iB906E3358B342190
    GO
    Isoform 4 (identifier: Q8IX04-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-38: Missing.
         376-379: AMEL → DIMI
         380-471: Missing.

    Show »
    Length:341
    Mass (Da):37,611
    Checksum:i7D5CD535296471FA
    GO
    Isoform 5 (identifier: Q8IX04-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         205-215: GIADRLVLLDL → VESRSVTQAGV
         216-471: Missing.

    Show »
    Length:215
    Mass (Da):24,233
    Checksum:iB82D7775A32AAB67
    GO
    Isoform 6 (identifier: Q8IX04-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         43-64: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:449
    Mass (Da):49,750
    Checksum:i2B5D772AEA5B1F51
    GO
    Isoform 7 (identifier: Q8IX04-7) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         65-164: Missing.
         239-295: Missing.
         354-470: VLTWSGQEEV...SIHSLQQQLK → GI

    Note: No experimental confirmation available.

    Show »
    Length:199
    Mass (Da):22,240
    Checksum:iA8FC6744B9B89325
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti148 – 1481D → G in BAG59405. (PubMed:14702039)Curated
    Sequence conflicti248 – 2481V → A in BAG59405. (PubMed:14702039)Curated
    Sequence conflicti366 – 3661H → L in AAN32950. (PubMed:12427560)Curated
    Sequence conflicti366 – 3661H → L in BAA91985. (PubMed:14702039)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 3838Missing in isoform 4. 1 PublicationVSP_023346Add
    BLAST
    Alternative sequencei43 – 6422Missing in isoform 3 and isoform 6. 2 PublicationsVSP_023347Add
    BLAST
    Alternative sequencei65 – 164100Missing in isoform 7. 1 PublicationVSP_045986Add
    BLAST
    Alternative sequencei205 – 21511GIADRLVLLDL → VESRSVTQAGV in isoform 5. 1 PublicationVSP_023348Add
    BLAST
    Alternative sequencei216 – 471256Missing in isoform 5. 1 PublicationVSP_023349Add
    BLAST
    Alternative sequencei239 – 29557Missing in isoform 7. 1 PublicationVSP_045987Add
    BLAST
    Alternative sequencei354 – 470117VLTWS…QQQLK → GI in isoform 7. 1 PublicationVSP_045988Add
    BLAST
    Alternative sequencei376 – 3794AMEL → DIMI in isoform 2, isoform 3 and isoform 4. 3 PublicationsVSP_023350
    Alternative sequencei380 – 47192Missing in isoform 2, isoform 3 and isoform 4. 3 PublicationsVSP_023351Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF503350 mRNA. Translation: AAN32950.1.
    CR616778 mRNA. No translation available.
    AK001930 mRNA. Translation: BAA91985.1.
    AK296835 mRNA. Translation: BAG59405.1.
    AK314521 mRNA. Translation: BAG37116.1.
    AC027544 Genomic DNA. No translation available.
    AC112694 Genomic DNA. No translation available.
    CH471064 Genomic DNA. Translation: EAW68380.1.
    BC011011 mRNA. Translation: AAH11011.2.
    BC064566 mRNA. Translation: AAH64566.1.
    CD109744 mRNA. No translation available.
    CCDSiCCDS41624.1. [Q8IX04-1]
    CCDS58122.1. [Q8IX04-4]
    CCDS58123.1. [Q8IX04-3]
    CCDS58124.1. [Q8IX04-6]
    CCDS58125.1. [Q8IX04-7]
    CCDS7843.1. [Q8IX04-2]
    RefSeqiNP_001035787.1. NM_001040697.2. [Q8IX04-1]
    NP_001248311.1. NM_001261382.1. [Q8IX04-6]
    NP_001248312.1. NM_001261383.1. [Q8IX04-3]
    NP_001248313.1. NM_001261384.1.
    NP_001248314.1. NM_001261385.1. [Q8IX04-4]
    NP_001248315.1. NM_001261386.1. [Q8IX04-7]
    NP_060784.3. NM_018314.4. [Q8IX04-2]
    XP_005253058.1. XM_005253001.1.
    UniGeneiHs.407991.

    Genome annotation databases

    EnsembliENST00000300038; ENSP00000300038; ENSG00000151116. [Q8IX04-5]
    ENST00000320750; ENSP00000323353; ENSG00000151116. [Q8IX04-3]
    ENST00000379387; ENSP00000368697; ENSG00000151116. [Q8IX04-6]
    ENST00000396197; ENSP00000379500; ENSG00000151116. [Q8IX04-1]
    ENST00000535484; ENSP00000441092; ENSG00000151116. [Q8IX04-4]
    ENST00000541984; ENSP00000437538; ENSG00000151116. [Q8IX04-7]
    ENST00000543987; ENSP00000442974; ENSG00000151116. [Q8IX04-2]
    GeneIDi55293.
    KEGGihsa:55293.
    UCSCiuc001mot.4. human. [Q8IX04-1]
    uc001mou.4. human. [Q8IX04-2]
    uc001mov.4. human. [Q8IX04-3]
    uc010rdh.3. human. [Q8IX04-5]
    uc031pzg.1. human. [Q8IX04-4]

    Polymorphism databases

    DMDMi126253820.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF503350 mRNA. Translation: AAN32950.1 .
    CR616778 mRNA. No translation available.
    AK001930 mRNA. Translation: BAA91985.1 .
    AK296835 mRNA. Translation: BAG59405.1 .
    AK314521 mRNA. Translation: BAG37116.1 .
    AC027544 Genomic DNA. No translation available.
    AC112694 Genomic DNA. No translation available.
    CH471064 Genomic DNA. Translation: EAW68380.1 .
    BC011011 mRNA. Translation: AAH11011.2 .
    BC064566 mRNA. Translation: AAH64566.1 .
    CD109744 mRNA. No translation available.
    CCDSi CCDS41624.1. [Q8IX04-1 ]
    CCDS58122.1. [Q8IX04-4 ]
    CCDS58123.1. [Q8IX04-3 ]
    CCDS58124.1. [Q8IX04-6 ]
    CCDS58125.1. [Q8IX04-7 ]
    CCDS7843.1. [Q8IX04-2 ]
    RefSeqi NP_001035787.1. NM_001040697.2. [Q8IX04-1 ]
    NP_001248311.1. NM_001261382.1. [Q8IX04-6 ]
    NP_001248312.1. NM_001261383.1. [Q8IX04-3 ]
    NP_001248313.1. NM_001261384.1.
    NP_001248314.1. NM_001261385.1. [Q8IX04-4 ]
    NP_001248315.1. NM_001261386.1. [Q8IX04-7 ]
    NP_060784.3. NM_018314.4. [Q8IX04-2 ]
    XP_005253058.1. XM_005253001.1.
    UniGenei Hs.407991.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2I6T X-ray 2.10 A/B 171-471 [» ]
    3DL2 X-ray 2.10 A/B 171-471 [» ]
    ProteinModelPortali Q8IX04.
    SMRi Q8IX04. Positions 8-143, 181-471.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120580. 6 interactions.
    IntActi Q8IX04. 7 interactions.
    STRINGi 9606.ENSP00000379500.

    PTM databases

    PhosphoSitei Q8IX04.

    Polymorphism databases

    DMDMi 126253820.

    Proteomic databases

    MaxQBi Q8IX04.
    PaxDbi Q8IX04.
    PRIDEi Q8IX04.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000300038 ; ENSP00000300038 ; ENSG00000151116 . [Q8IX04-5 ]
    ENST00000320750 ; ENSP00000323353 ; ENSG00000151116 . [Q8IX04-3 ]
    ENST00000379387 ; ENSP00000368697 ; ENSG00000151116 . [Q8IX04-6 ]
    ENST00000396197 ; ENSP00000379500 ; ENSG00000151116 . [Q8IX04-1 ]
    ENST00000535484 ; ENSP00000441092 ; ENSG00000151116 . [Q8IX04-4 ]
    ENST00000541984 ; ENSP00000437538 ; ENSG00000151116 . [Q8IX04-7 ]
    ENST00000543987 ; ENSP00000442974 ; ENSG00000151116 . [Q8IX04-2 ]
    GeneIDi 55293.
    KEGGi hsa:55293.
    UCSCi uc001mot.4. human. [Q8IX04-1 ]
    uc001mou.4. human. [Q8IX04-2 ]
    uc001mov.4. human. [Q8IX04-3 ]
    uc010rdh.3. human. [Q8IX04-5 ]
    uc031pzg.1. human. [Q8IX04-4 ]

    Organism-specific databases

    CTDi 55293.
    GeneCardsi GC11M018554.
    HGNCi HGNC:30866. UEVLD.
    HPAi HPA047134.
    MIMi 610985. gene.
    neXtProti NX_Q8IX04.
    PharmGKBi PA147357188.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0039.
    HOGENOMi HOG000213793.
    HOVERGENi HBG000462.
    InParanoidi Q8IX04.
    OMAi NIPIRLW.
    OrthoDBi EOG7JT6WH.
    PhylomeDBi Q8IX04.
    TreeFami TF314963.

    Miscellaneous databases

    EvolutionaryTracei Q8IX04.
    GenomeRNAii 55293.
    NextBioi 59482.
    PROi Q8IX04.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8IX04.
    Bgeei Q8IX04.
    CleanExi HS_UEVLD.
    Genevestigatori Q8IX04.

    Family and domain databases

    Gene3Di 3.10.110.10. 1 hit.
    3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProi IPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR016040. NAD(P)-bd_dom.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    IPR008883. UEV_N.
    [Graphical view ]
    Pfami PF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    PF05743. UEV. 1 hit.
    [Graphical view ]
    PRINTSi PR00086. LLDHDRGNASE.
    SUPFAMi SSF54495. SSF54495. 1 hit.
    SSF56327. SSF56327. 1 hit.
    PROSITEi PS51322. UEV. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of UEV3, a human cDNA with similarities to inactive E2 ubiquitin-conjugating enzymes."
      Kloor M., Bork P., Duwe A., Klaes R., von Knebel Doeberitz M., Ridder R.
      Biochim. Biophys. Acta 1579:219-224(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, TISSUE SPECIFICITY.
      Tissue: PlacentaImported.
    2. "Full-length cDNA libraries and normalization."
      Li W.B., Gruber C., Jessee J., Polayes D.
      Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Neuroblastoma.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 4 AND 6).
      Tissue: PlacentaImported, Testis and Tongue.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 5 AND 7).
      Tissue: Brain, Placenta and TestisImported.
    7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. "Structural investigation into the L-lactate dehydrogenase domain of human ubiquitin-conjugating enzyme E2-like isoform A."
      Avvakumov G.V., Walker J.R., Xue S., Newman E.M., Finerty P.J. Jr., Butler-Cole C., Tempel W., Weigelt J., Sundstrom M., Arrowsmith C.H., Edwards A.M., Bochkarev A., Dhe-Paganon S.
      Submitted (OCT-2006) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS).

    Entry informationi

    Entry nameiUEVLD_HUMAN
    AccessioniPrimary (citable) accession number: Q8IX04
    Secondary accession number(s): B2RB69
    , B4DL43, F5H6L6, H7BYD6, Q6P2F0, Q96FF5, Q9NUX7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 112 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3