Q8IX04 (UEVLD_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ubiquitin-conjugating enzyme E2 variant 3
Short name=UEV-3

Alternative name(s):
EV and lactate/malate dehydrogenase domain-containing protein

Gene names

Name:	UEVLD
Synonyms:	UEV3

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Possible negative regulator of polyubiquitination. Ref.1
Subunit structure	Homodimer.
Tissue specificity	Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes. Ref.1
Sequence similarities	In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily. In the C-terminal section; belongs to the LDH/MDH superfamily. Contains 1 UEV (ubiquitin E2 variant) domain.

Ontologies

Keywords
Biological process	Ubl conjugation pathway
Coding sequence diversity	Alternative splicing
Ligand	NAD
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro cellular protein modification process Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: InterPro
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 7 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 Ref.3 (identifier: Q8IX04-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 Ref.1 (identifier: Q8IX04-2)

The sequence of this isoform differs from the canonical sequence as follows:
     376-379: AMEL → DIMI
     380-471: Missing.

Isoform 3 Ref.6 (identifier: Q8IX04-3)

The sequence of this isoform differs from the canonical sequence as follows:
     43-64: Missing.
     376-379: AMEL → DIMI
     380-471: Missing.

Isoform 4 (identifier: Q8IX04-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-38: Missing.
     376-379: AMEL → DIMI
     380-471: Missing.

Isoform 5 (identifier: Q8IX04-5)

The sequence of this isoform differs from the canonical sequence as follows:
     205-215: GIADRLVLLDL → VESRSVTQAGV
     216-471: Missing.

Isoform 6 (identifier: Q8IX04-6)

The sequence of this isoform differs from the canonical sequence as follows:
     43-64: Missing.

Note: No experimental confirmation available.

Isoform 7 (identifier: Q8IX04-7)

The sequence of this isoform differs from the canonical sequence as follows:
     65-164: Missing.
     239-295: Missing.
     354-470: VLTWSGQEEV...SIHSLQQQLK → GI

Note: No experimental confirmation available.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 471

471

Ubiquitin-conjugating enzyme E2 variant 3

PRO_0000278651

Regions

Domain

2 – 145

144

UEV

Nucleotide binding

191 – 219

29

NAD By similarity

Natural variations

Alternative sequence

1 – 38

38

Missing in isoform 4.

VSP_023346

Alternative sequence

43 – 64

22

Missing in isoform 3 and isoform 6. Ref.6

VSP_023347

Alternative sequence

65 – 164

100

Missing in isoform 7.

VSP_045986

Alternative sequence

205 – 215

11

GIADRLVLLDL → VESRSVTQAGV in isoform 5.

VSP_023348

Alternative sequence

216 – 471

256

Missing in isoform 5.

VSP_023349

Alternative sequence

239 – 295

57

Missing in isoform 7.

VSP_045987

Alternative sequence

354 – 470

117

VLTWS…QQQLK → GI in isoform 7.

VSP_045988

Alternative sequence

376 – 379

4

AMEL → DIMI in isoform 2, isoform 3 and isoform 4.

VSP_023350

Alternative sequence

380 – 471

92

Missing in isoform 2, isoform 3 and isoform 4.

VSP_023351

Experimental info

Sequence conflict

148

1

D → G in BAG59405. Ref.3

Sequence conflict

248

1

V → A in BAG59405. Ref.3

Sequence conflict

366

1

H → L in AAN32950. Ref.1

Sequence conflict

366

1

H → L in BAA91985. Ref.3

Secondary structure

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471

Helix Strand Turn

Details...

Beta strand

184 – 188

5

Helix

192 – 204

13

Beta strand

208 – 213

6

Helix

218 – 220

3

Helix

223 – 229

7

Beta strand

234 – 238

5

Helix

240 – 243

4

Beta strand

247 – 251

5

Helix

262 – 283

22

Turn

284 – 286

3

Beta strand

288 – 291

4

Beta strand

293 – 295

3

Helix

296 – 307

12

Helix

311 – 313

3

Beta strand

314 – 316

3

Helix

320 – 332

13

Helix

339 – 342

4

Beta strand

343 – 348

6

Beta strand

350 – 352

3

Beta strand

354 – 358

5

Helix

366 – 377

12

Beta strand

380 – 382

3

Helix

387 – 402

16

Beta strand

407 – 414

8

Beta strand

426 – 434

9

Beta strand

437 – 441

5

Helix

450 – 468

19

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified February 20, 2007. Version 2. Checksum: 2502659A566E7DDD	FASTA	471	52,264
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYVFKDSSQK DLLNFTGTIP 70 80 90 100 110 120 VMYQGNTYNI PIRFWILDSH PFAPPICFLK PTANMGILVG KHVDAQGRIY LPYLQNWSHP 130 140 150 160 170 180 KSVIVGLIKE MIAKFQEELP MYSLSSSDEA RQVDLLAYIA KITEGVSDTN SKSWANHENK 190 200 210 220 230 240 TVNKITVVGG GELGIACTLA ISAKGIADRL VLLDLSEGTK GATMDLEIFN LPNVEISKDL 250 260 270 280 290 300 SASAHSKVVI FTVNSLGSSQ SYLDVVQSNV DMFRALVPAL GHYSQHSVLL VASQPVEIMT 310 320 330 340 350 360 YVTWKLSTFP ANRVIGIGCN LDSQRLQYII TNVLKAQTSG KEVWVIGEQG EDKVLTWSGQ 370 380 390 400 410 420 EEVVSHTSQV QLSNRAMELL RVKGQRSWSV GLSVADMVDS IVNNKKKVHS VSALAKGYYD 430 440 450 460 470 INSEVFLSLP CILGTNGVSE VIKTTLKEDT VTEKLQSSAS SIHSLQQQLK L
	Isoform 2 [UniParc]. Checksum: 100BCD1FA295FC60	FASTA	379	42,292
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYVFKDSSQK DLLNFTGTIP 70 80 90 100 110 120 VMYQGNTYNI PIRFWILDSH PFAPPICFLK PTANMGILVG KHVDAQGRIY LPYLQNWSHP 130 140 150 160 170 180 KSVIVGLIKE MIAKFQEELP MYSLSSSDEA RQVDLLAYIA KITEGVSDTN SKSWANHENK 190 200 210 220 230 240 TVNKITVVGG GELGIACTLA ISAKGIADRL VLLDLSEGTK GATMDLEIFN LPNVEISKDL 250 260 270 280 290 300 SASAHSKVVI FTVNSLGSSQ SYLDVVQSNV DMFRALVPAL GHYSQHSVLL VASQPVEIMT 310 320 330 340 350 360 YVTWKLSTFP ANRVIGIGCN LDSQRLQYII TNVLKAQTSG KEVWVIGEQG EDKVLTWSGQ 370 EEVVSHTSQV QLSNRDIMI
	Isoform 3 [UniParc]. Checksum: B906E3358B342190	FASTA	357	39,778
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYGNTYNIPI RFWILDSHPF 70 80 90 100 110 120 APPICFLKPT ANMGILVGKH VDAQGRIYLP YLQNWSHPKS VIVGLIKEMI AKFQEELPMY 130 140 150 160 170 180 SLSSSDEARQ VDLLAYIAKI TEGVSDTNSK SWANHENKTV NKITVVGGGE LGIACTLAIS 190 200 210 220 230 240 AKGIADRLVL LDLSEGTKGA TMDLEIFNLP NVEISKDLSA SAHSKVVIFT VNSLGSSQSY 250 260 270 280 290 300 LDVVQSNVDM FRALVPALGH YSQHSVLLVA SQPVEIMTYV TWKLSTFPAN RVIGIGCNLD 310 320 330 340 350 SQRLQYIITN VLKAQTSGKE VWVIGEQGED KVLTWSGQEE VVSHTSQVQL SNRDIMI
	Isoform 4 [UniParc]. Checksum: 7D5CD535296471FA	FASTA	341	37,611
	10 20 30 40 50 60 MDTYVFKDSS QKDLLNFTGT IPVMYQGNTY NIPIRFWILD SHPFAPPICF LKPTANMGIL 70 80 90 100 110 120 VGKHVDAQGR IYLPYLQNWS HPKSVIVGLI KEMIAKFQEE LPMYSLSSSD EARQVDLLAY 130 140 150 160 170 180 IAKITEGVSD TNSKSWANHE NKTVNKITVV GGGELGIACT LAISAKGIAD RLVLLDLSEG 190 200 210 220 230 240 TKGATMDLEI FNLPNVEISK DLSASAHSKV VIFTVNSLGS SQSYLDVVQS NVDMFRALVP 250 260 270 280 290 300 ALGHYSQHSV LLVASQPVEI MTYVTWKLST FPANRVIGIG CNLDSQRLQY IITNVLKAQT 310 320 330 340 SGKEVWVIGE QGEDKVLTWS GQEEVVSHTS QVQLSNRDIM I
	Isoform 5 [UniParc]. Checksum: B82D7775A32AAB67	FASTA	215	24,233
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYVFKDSSQK DLLNFTGTIP 70 80 90 100 110 120 VMYQGNTYNI PIRFWILDSH PFAPPICFLK PTANMGILVG KHVDAQGRIY LPYLQNWSHP 130 140 150 160 170 180 KSVIVGLIKE MIAKFQEELP MYSLSSSDEA RQVDLLAYIA KITEGVSDTN SKSWANHENK 190 200 210 TVNKITVVGG GELGIACTLA ISAKVESRSV TQAGV
	Isoform 6 [UniParc]. Checksum: 2B5D772AEA5B1F51	FASTA	449	49,750
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYGNTYNIPI RFWILDSHPF 70 80 90 100 110 120 APPICFLKPT ANMGILVGKH VDAQGRIYLP YLQNWSHPKS VIVGLIKEMI AKFQEELPMY 130 140 150 160 170 180 SLSSSDEARQ VDLLAYIAKI TEGVSDTNSK SWANHENKTV NKITVVGGGE LGIACTLAIS 190 200 210 220 230 240 AKGIADRLVL LDLSEGTKGA TMDLEIFNLP NVEISKDLSA SAHSKVVIFT VNSLGSSQSY 250 260 270 280 290 300 LDVVQSNVDM FRALVPALGH YSQHSVLLVA SQPVEIMTYV TWKLSTFPAN RVIGIGCNLD 310 320 330 340 350 360 SQRLQYIITN VLKAQTSGKE VWVIGEQGED KVLTWSGQEE VVSHTSQVQL SNRAMELLRV 370 380 390 400 410 420 KGQRSWSVGL SVADMVDSIV NNKKKVHSVS ALAKGYYDIN SEVFLSLPCI LGTNGVSEVI 430 440 KTTLKEDTVT EKLQSSASSI HSLQQQLKL
	Isoform 7 [UniParc]. Checksum: A8FC6744B9B89325	FASTA	199	22,240
	10 20 30 40 50 60 MEFDCEGLRR LLGKYKFRDL TVEELRNVNV FFPHFKYSMD TYVFKDSSQK DLLNFTGTIP 70 80 90 100 110 120 VMYQGVSDTN SKSWANHENK TVNKITVVGG GELGIACTLA ISAKGIADRL VLLDLSEGTK 130 140 150 160 170 180 GATMDLEIFN LPNVEISKVE IMTYVTWKLS TFPANRVIGI GCNLDSQRLQ YIITNVLKAQ 190 TSGKEVWVIG EQGEDKGIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of UEV3, a human cDNA with similarities to inactive E2 ubiquitin-conjugating enzymes." Kloor M., Bork P., Duwe A., Klaes R., von Knebel Doeberitz M., Ridder R. Biochim. Biophys. Acta 1579:219-224(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, TISSUE SPECIFICITY. Tissue: Placenta.
[2]	"Full-length cDNA libraries and normalization." Li W.B., Gruber C., Jessee J., Polayes D. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Neuroblastoma.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 4 AND 6). Tissue: Placenta, Testis and Tongue.
[4]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 5 AND 7). Tissue: Brain, Placenta and Testis.
[7]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]	"Structural investigation into the L-lactate dehydrogenase domain of human ubiquitin-conjugating enzyme E2-like isoform A." Avvakumov G.V., Walker J.R., Xue S., Newman E.M., Finerty P.J. Jr., Butler-Cole C., Tempel W., Weigelt J., Sundstrom M., Arrowsmith C.H., Edwards A.M., Bochkarev A., Dhe-Paganon S. Submitted (OCT-2006) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF503350 mRNA. Translation: AAN32950.1.
CR616778 mRNA. No translation available.
AK001930 mRNA. Translation: BAA91985.1.
AK296835 mRNA. Translation: BAG59405.1.
AK314521 mRNA. Translation: BAG37116.1.
AC027544 Genomic DNA. No translation available.
AC112694 Genomic DNA. No translation available.
CH471064 Genomic DNA. Translation: EAW68380.1.
BC011011 mRNA. Translation: AAH11011.2.
BC064566 mRNA. Translation: AAH64566.1.
CD109744 mRNA. No translation available.

IPI

IPI00185072.
IPI00217342.
IPI00440160.
IPI00746183.
IPI00827694.
IPI01010780.
IPI01014900.

RefSeq

NP_001035787.1. NM_001040697.2.
NP_001248311.1. NM_001261382.1.
NP_001248312.1. NM_001261383.1.
NP_001248313.1. NM_001261384.1.
NP_001248314.1. NM_001261385.1.
NP_001248315.1. NM_001261386.1.
NP_060784.3. NM_018314.4.

UniGene

Hs.407991.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2I6T	X-ray	2.10	A/B	171-471	[»]
3DL2	X-ray	2.10	A/B	171-471	[»]

ProteinModelPortal

Q8IX04.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q8IX04. 7 interactions.

STRING

9606.ENSP00000379500.

PTM databases

PhosphoSite

Q8IX04.

Polymorphism databases

DMDM

126253820.

Proteomic databases

PaxDb

Q8IX04.

PRIDE

Q8IX04.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000300038; ENSP00000300038; ENSG00000151116.
ENST00000320750; ENSP00000323353; ENSG00000151116.
ENST00000379387; ENSP00000368697; ENSG00000151116.
ENST00000396197; ENSP00000379500; ENSG00000151116.
ENST00000535484; ENSP00000441092; ENSG00000151116.
ENST00000541984; ENSP00000437538; ENSG00000151116.
ENST00000543987; ENSP00000442974; ENSG00000151116.

GeneID

55293.

KEGG

hsa:55293.

UCSC

uc001mot.3. human.
uc001mou.3. human.
uc001mov.3. human.
uc010rdh.2. human.

Organism-specific databases

CTD

55293.

GeneCards

GC11M018554.

HGNC

HGNC:30866. UEVLD.

HPA

HPA047134.

MIM

610985. gene.

neXtProt

NX_Q8IX04.

PharmGKB

PA147357188.

GenAtlas

Search...

Phylogenomic databases

eggNOG

COG0039.

HOGENOM

HOG000213793.

HOVERGEN

HBG000462.

InParanoid

Q8IX04.

OMA

SNRAMEL.

Gene expression databases

ArrayExpress

Q8IX04.

Bgee

Q8IX04.

CleanEx

HS_UEVLD.

Genevestigator

Q8IX04.

Family and domain databases

Gene3D

3.10.110.10. 1 hit.
3.40.50.720. 1 hit.
3.90.110.10. 1 hit.

InterPro

IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
IPR016135. UBQ-conjugating_enzyme/RWD.
IPR008883. UEV_N.
[Graphical view]

Pfam

PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
PF05743. UEV. 1 hit.
[Graphical view]

PRINTS

PR00086. LLDHDRGNASE.

SUPFAM

SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
SSF54495. UBQ-conjugat/RWD-like. 1 hit.

PROSITE

PS00183. UBIQUITIN_CONJUGAT_1. False negative.
PS50127. UBIQUITIN_CONJUGAT_2. False negative.
PS51322. UEV. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q8IX04.

GenomeRNAi

55293.

NextBio

59482.

SOURCE

Search...

Entry information

Entry name

UEVLD_HUMAN

Accession

Primary (citable) accession number: Q8IX04
Secondary accession number(s): B2RB69 , B4DL43, F5H6L6, H7BYD6, Q6P2F0, Q96FF5, Q9NUX7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 100 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.