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Protein

Putative ubiquitin-conjugating enzyme E2 D2-like protein

Gene

UBE2DNL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Enzyme and pathway databases

SignaLinkiQ8IWF7.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ubiquitin-conjugating enzyme E2 D2-like protein
Alternative name(s):
Ubiquitin carrier protein D2-like
Ubiquitin-conjugating enzyme E2D N-terminal-like
Ubiquitin-protein ligase D2-like
Gene namesi
Name:UBE2DNL
Synonyms:UBE2D2L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:28656. UBE2DNL.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7575Putative ubiquitin-conjugating enzyme E2 D2-like proteinPRO_0000254089Add
BLAST

Proteomic databases

PRIDEiQ8IWF7.

Interactioni

Protein-protein interaction databases

IntActiQ8IWF7. 11 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ8IWF7.
SMRiQ8IWF7. Positions 1-73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG083927.
InParanoidiQ8IWF7.
PhylomeDBiQ8IWF7.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IWF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKLIHKEF LELARDPQPH CSAGPVWDDM LHWQATITRP NDSSYLGGVF
60 70
FLKFPSDYLF KPPKIKFTNG IYHQR
Length:75
Mass (Da):8,761
Last modified:March 1, 2003 - v1
Checksum:i97FF955C48458183
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040290 mRNA. No translation available.
UniGeneiHs.460809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040290 mRNA. No translation available.
UniGeneiHs.460809.

3D structure databases

ProteinModelPortaliQ8IWF7.
SMRiQ8IWF7. Positions 1-73.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IWF7. 11 interactions.

Proteomic databases

PRIDEiQ8IWF7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiUBE2DNL.
HGNCiHGNC:28656. UBE2DNL.
neXtProtiNX_Q8IWF7.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG083927.
InParanoidiQ8IWF7.
PhylomeDBiQ8IWF7.

Enzyme and pathway databases

SignaLinkiQ8IWF7.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiU2D2L_HUMAN
AccessioniPrimary (citable) accession number: Q8IWF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2003
Last modified: October 14, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene. Probably inactive as a ubiquitin-conjugating enzyme since it lacks the essential active site cysteine.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.