##gff-version 3
Q8IWE5	UniProtKB	Chain	1	1019	.	.	.	ID=PRO_0000309455;Note=Pleckstrin homology domain-containing family M member 2	
Q8IWE5	UniProtKB	Domain	36	158	.	.	.	Note=RUN;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00178	
Q8IWE5	UniProtKB	Domain	771	873	.	.	.	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145	
Q8IWE5	UniProtKB	Region	1	310	.	.	.	Note=Interaction with KIF5B;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15905402;Dbxref=PMID:15905402	
Q8IWE5	UniProtKB	Region	230	458	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Region	471	525	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Region	557	581	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Region	762	885	.	.	.	Note=Interaction with sifA	
Q8IWE5	UniProtKB	Compositional bias	237	294	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Compositional bias	352	366	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Compositional bias	374	389	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Compositional bias	413	435	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8IWE5	UniProtKB	Modified residue	1	1	.	.	.	Note=N-acetylmethionine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378	
Q8IWE5	UniProtKB	Modified residue	441	441	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q80TQ5	
Q8IWE5	UniProtKB	Alternative sequence	218	237	.	.	.	ID=VSP_061018;Note=In isoform 2. Missing	
Q8IWE5	UniProtKB	Natural variant	32	32	.	.	.	ID=VAR_036950;Note=I->T;Dbxref=dbSNP:rs12091750	
Q8IWE5	UniProtKB	Mutagenesis	207	208	.	.	.	Note=No effect on lysosomal location%3B loss of interaction with kinesin-1 and movement of lysosomes to the periphery%3B when associated with A-236-237-A. WD->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22172677;Dbxref=PMID:22172677	
Q8IWE5	UniProtKB	Mutagenesis	236	237	.	.	.	Note=No effect on lysosomal location%3B loss of interaction with kinesin-1 and movement of lysosomes to the periphery%3B when associated with A-207-208-A. WE->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22172677;Dbxref=PMID:22172677	
Q8IWE5	UniProtKB	Mutagenesis	828	828	.	.	.	Note=Loss of interaction with sifA. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18996344;Dbxref=PMID:18996344	
Q8IWE5	UniProtKB	Mutagenesis	830	830	.	.	.	Note=Loss of interaction with sifA. R->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18996344;Dbxref=PMID:18996344	
Q8IWE5	UniProtKB	Mutagenesis	831	831	.	.	.	Note=Alters interaction with sifA. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18996344;Dbxref=PMID:18996344	
Q8IWE5	UniProtKB	Mutagenesis	869	869	.	.	.	Note=Loss of interaction with sifA. C->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18996344;Dbxref=PMID:18996344	
Q8IWE5	UniProtKB	Sequence conflict	600	602	.	.	.	Note=VFR->ASG;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8IWE5	UniProtKB	Turn	210	212	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3ZFW	
Q8IWE5	UniProtKB	Beta strand	774	780	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	787	789	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3HW2	
Q8IWE5	UniProtKB	Beta strand	793	800	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	803	811	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	816	820	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	826	831	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	840	845	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Beta strand	851	854	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB	
Q8IWE5	UniProtKB	Helix	858	872	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CXB