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Unreviewed, UniProtKB/TrEMBL Q8IWE0 (Q8IWE0_HUMAN)

Last modified February 9, 2010. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Calcium/calmodulin-dependent protein kinase II alpha EMBL AAH40457.1
Gene names
Name: CAMK2A EMBL AAH40457.1
OrganismHomo sapiens (Human) EMBL AAH40457.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length478 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

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Sequences

Sequence LengthMass (Da)Tools
Q8IWE0-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: BAE143AA03BA9264

FASTA47854,088
        10         20         30         40         50         60 
MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARDHQKLERE 

        70         80         90        100        110        120 
ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED IVAREYYSEA DASHCIQQIL 

       130        140        150        160        170        180 
EAVLHCHQMG VVHRDLKPEN LLLASKLKGA AVKLADFGLA IEVEGEQQAW FGFAGTPGYL 

       190        200        210        220        230        240 
SPEVLRKDPY GKPVDLWACG VILYILLVGY PPFWDEDQHR LYKQIKAGAY DFPSPEWDTV 

       250        260        270        280        290        300 
TPEAKDLINK MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK 

       310        320        330        340        350        360 
GAILTTMLAT RNFSGGKSGG NKKSDGVKES SESTNTTIED EDTKVRKQEI IKVTEQLIEA 

       370        380        390        400        410        420 
ISNGDFESYT KMCDPGMTAF EPEALGNLVE GLDFHRFYFE NLWSRNSKPV HTTILNPHIH 

       430        440        450        460        470 
LMGDESACIA YIRITQYLDA GGIPRTAQSE ETRVWHRRDG KWQIVHFHRS GAPSVLPH

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References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain EMBL AAH40457.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC040457 mRNA. Translation: AAH40457.1.
IPIIPI00215715.
RefSeqNP_057065.2.
NP_741960.1.

3D structure databases

HSSPHSSP built from PDB template 1HKX based on UniProtKB P11798.
SMRQ8IWE0. Positions 10-308, 336-474.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8IWE0.

Genome annotation databases

EnsemblENST00000348628; ENSP00000261793; ENSG00000070808; Homo sapiens. [Genome view]
GeneID815.
KEGGhsa:815.

Organism-specific databases

CTD815.
HGNCHGNC:1460. CAMK2A.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ8IWE0.

Gene expression databases

ArrayExpressQ8IWE0.
BgeeQ8IWE0.

Family and domain databases

InterProIPR020636. Ca/CaM-dep_prot_kinase-like.
IPR015742. Ca/CaM-dep_prot_kinase_2.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR017442. Se/Thr_prot_kinase-like_dom.
IPR008271. Ser/Thr_prot_kinase_AS.
IPR002290. Ser/Thr_prot_kinase_dom.
[Graphical view]
PANTHERPTHR22982. Ca/CaM-dep_prot_kinase-like. 1 hit.
PTHR22982:SF64. CaMKII. 1 hit.
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ8IWE0_HUMAN
AccessionPrimary (citable) accession number: Q8IWE0
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: February 9, 2010
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information