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Protein

Spermatogenesis-associated protein 31A7

Gene

SPATA31A7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in spermatogenesis.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31A7Curated
Alternative name(s):
Protein FAM75A7Curated
Gene namesi
Name:SPATA31A7Imported
Synonyms:FAM75A4Imported, FAM75A7Imported, SPATA31A4Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:32007. SPATA31A7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162387900.

Polymorphism and mutation databases

BioMutaiSPATA31A7.
DMDMi166215080.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13471347Spermatogenesis-associated protein 31A7PRO_0000280245Add
BLAST

Proteomic databases

PaxDbiQ8IWB4.
PeptideAtlasiQ8IWB4.
PRIDEiQ8IWB4.

PTM databases

iPTMnetiQ8IWB4.
PhosphoSiteiQ8IWB4.

Expressioni

Gene expression databases

BgeeiENSG00000234214.
CleanExiHS_FAM75A7.
GenevisibleiQ8IWB4. HS.

Interactioni

Protein-protein interaction databases

BioGridi117591. 2 interactions.
IntActiQ8IWB4. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ8IWB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi120 – 228109Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the SPATA31 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IF6X. Eukaryota.
ENOG4111EH8. LUCA.
GeneTreeiENSGT00530000063191.
HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ8IWB4.
OMAiTHEIAKV.
OrthoDBiEOG091G024V.
PhylomeDBiQ8IWB4.
TreeFamiTF338531.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IWB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR
60 70 80 90 100
CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECPRG LEETSDLLSQ
110 120 130 140 150
LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS
160 170 180 190 200
PLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP
210 220 230 240 250
PALFPHPPHT PDPLACSLPP PKGFTAPPLR DSTLITPSHC DSVAFPLGTV
260 270 280 290 300
PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD
310 320 330 340 350
HLSRHPPETC QMEAGSLFLL SSDGQNVVGI QVTETAKVNI WEEKENVGSF
360 370 380 390 400
TNRMTPEKHL NYLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKLSD
410 420 430 440 450
PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM
460 470 480 490 500
SNVCPIQRET TMSPLLFQAQ PLSHLGPECQ PFISSTPQFR PTPMAQAEAQ
510 520 530 540 550
AHLQSSFPVL SPAFPSLIQN TGVACPASQN KVQALSLPET QHPEWPLLRR
560 570 580 590 600
QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE
610 620 630 640 650
QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG
660 670 680 690 700
ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE
710 720 730 740 750
LERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVCV
760 770 780 790 800
RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL
810 820 830 840 850
GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG
860 870 880 890 900
AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR
910 920 930 940 950
GIPSWNDHEP LKPPPAGQEG RWPSKPLTYS LTGSIQQSRS LGAQSSKAGE
960 970 980 990 1000
TREAVPQCRV PLETCMLANL QATSEDVHGF EAPGTSKSSL HPRVSVSQDP
1010 1020 1030 1040 1050
RKLCLMEEVV NEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV
1060 1070 1080 1090 1100
SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRN PNCQGSCKSQ
1110 1120 1130 1140 1150
RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL
1160 1170 1180 1190 1200
LPSKKQPPSV SPFGENIKQI FQWIFSKKKS KPAPVTAESQ KTVKNRSRVY
1210 1220 1230 1240 1250
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH
1260 1270 1280 1290 1300
RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ
1310 1320 1330 1340
WGLRHPQILH PKKAVSPVSP PQHWPKTSGA SSHHHHCPRH CLLWEGI
Length:1,347
Mass (Da):148,734
Last modified:January 15, 2008 - v4
Checksum:iBE571EC6050FF9A9
GO

Sequence cautioni

The sequence AAH40528 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411L → V in CAI95396 (PubMed:15164053).Curated
Sequence conflicti64 – 641C → S in AAH40528 (PubMed:15489334).Curated
Sequence conflicti88 – 881P → R in CAI95396 (PubMed:15164053).Curated
Sequence conflicti297 – 2971V → A in AAH40528 (PubMed:15489334).Curated
Sequence conflicti362 – 3621Y → S in CAI95396 (PubMed:15164053).Curated
Sequence conflicti472 – 4721L → P in AAH40528 (PubMed:15489334).Curated
Sequence conflicti625 – 6251Q → R in AAH40528 (PubMed:15489334).Curated
Sequence conflicti749 – 7491C → R in CAI95396 (PubMed:15164053).Curated
Sequence conflicti1199 – 11991V → A in AAH40528 (PubMed:15489334).Curated
Sequence conflicti1219 – 12191E → K in CAI95396 (PubMed:15164053).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596385 Genomic DNA. Translation: CAI95396.1.
BX005040 Genomic DNA. No translation available.
BC040528 mRNA. Translation: AAH40528.1. Different initiation.
CCDSiCCDS75838.1.
PIRiT12532.
RefSeqiNP_056482.2. NM_015667.2.
UniGeneiHs.123004.
Hs.645497.

Genome annotation databases

EnsembliENST00000619167; ENSP00000484807; ENSG00000276040.
GeneIDi26165.
KEGGihsa:26165.
UCSCiuc033ctg.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596385 Genomic DNA. Translation: CAI95396.1.
BX005040 Genomic DNA. No translation available.
BC040528 mRNA. Translation: AAH40528.1. Different initiation.
CCDSiCCDS75838.1.
PIRiT12532.
RefSeqiNP_056482.2. NM_015667.2.
UniGeneiHs.123004.
Hs.645497.

3D structure databases

ProteinModelPortaliQ8IWB4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117591. 2 interactions.
IntActiQ8IWB4. 1 interaction.

PTM databases

iPTMnetiQ8IWB4.
PhosphoSiteiQ8IWB4.

Polymorphism and mutation databases

BioMutaiSPATA31A7.
DMDMi166215080.

Proteomic databases

PaxDbiQ8IWB4.
PeptideAtlasiQ8IWB4.
PRIDEiQ8IWB4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000619167; ENSP00000484807; ENSG00000276040.
GeneIDi26165.
KEGGihsa:26165.
UCSCiuc033ctg.2. human.

Organism-specific databases

CTDi26165.
GeneCardsiSPATA31A7.
HGNCiHGNC:32007. SPATA31A7.
MIMi616584. gene.
neXtProtiNX_Q8IWB4.
PharmGKBiPA162387900.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF6X. Eukaryota.
ENOG4111EH8. LUCA.
GeneTreeiENSGT00530000063191.
HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ8IWB4.
OMAiTHEIAKV.
OrthoDBiEOG091G024V.
PhylomeDBiQ8IWB4.
TreeFamiTF338531.

Miscellaneous databases

GenomeRNAii26165.
PROiQ4VX67.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000234214.
CleanExiHS_FAM75A7.
GenevisibleiQ8IWB4. HS.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS31A7_HUMAN
AccessioniPrimary (citable) accession number: Q8IWB4
Secondary accession number(s): Q4VX67, Q5TZK4, Q9Y4Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: January 15, 2008
Last modified: September 7, 2016
This is version 86 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.