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Protein

Protein FAM219A

Gene

FAM219A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM219A
Gene namesi
Name:FAM219A
Synonyms:C9orf25
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:19920. FAM219A.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134916501.

Polymorphism and mutation databases

BioMutaiFAM219A.
DMDMi209572756.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Protein FAM219APRO_0000089676Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineCombined sources
Modified residuei47 – 471PhosphoserineCombined sources
Modified residuei72 – 721PhosphoserineBy similarity
Modified residuei102 – 1021PhosphoserineCombined sources
Modified residuei113 – 1131PhosphothreonineCombined sources
Modified residuei115 – 1151PhosphoserineCombined sources
Modified residuei122 – 1221PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ8IW50.
PaxDbiQ8IW50.
PRIDEiQ8IW50.

PTM databases

iPTMnetiQ8IW50.
SwissPalmiQ8IW50.

Expressioni

Gene expression databases

BgeeiQ8IW50.
CleanExiHS_C9orf25.
ExpressionAtlasiQ8IW50. baseline and differential.
GenevisibleiQ8IW50. HS.

Organism-specific databases

HPAiHPA019338.
HPA052909.

Interactioni

Protein-protein interaction databases

BioGridi128461. 30 interactions.
IntActiQ8IW50. 7 interactions.
MINTiMINT-1369005.

Structurei

3D structure databases

ProteinModelPortaliQ8IW50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM219 family.Curated

Phylogenomic databases

eggNOGiENOG410IVPC. Eukaryota.
ENOG410Y14P. LUCA.
GeneTreeiENSGT00390000000860.
HOVERGENiHBG054822.
InParanoidiQ8IW50.
OMAiSERHAFH.
OrthoDBiEOG7V7689.
PhylomeDBiQ8IW50.
TreeFamiTF331928.

Family and domain databases

InterProiIPR029339. FAM219.
[Graphical view]
PANTHERiPTHR31281. PTHR31281. 1 hit.
PfamiPF15260. FAM219A. 1 hit.
[Graphical view]

Sequences (7)i

Sequence statusi: Complete.

This entry describes 7 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8IW50-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MMEEIDRFQV PTAHSEMQPL DPAAASISDG DCDAREGESV AMNYKPSPLQ
60 70 80 90 100
VKLEKQRELA RKGSLKNGSM GSPVNQQPKK NNVMARTRLV VPNKGYSSLD
110 120 130 140 150
QSPDEKPLVA LDTDSDDDFD MSRYSSSGYS SAEQINQDLN IQLLKDGYRL
160 170 180
DEIPDDEDLD LIPPKSVNPT CMCCQATSST ACHIQ
Length:185
Mass (Da):20,400
Last modified:October 14, 2008 - v3
Checksum:i114C59F2A3307D1E
GO
Isoform 2 (identifier: Q8IW50-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     10-20: Missing.
     37-53: Missing.

Show »
Length:157
Mass (Da):17,365
Checksum:i577A4FA4A6B7DC74
GO
Isoform 3 (identifier: Q8IW50-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     10-20: Missing.
     37-53: Missing.
     134-134: Missing.

Show »
Length:156
Mass (Da):17,237
Checksum:i23C408A7E30506A4
GO
Isoform 4 (identifier: Q8IW50-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     10-20: Missing.
     134-134: Missing.

Show »
Length:173
Mass (Da):19,080
Checksum:i1AC61D0AE876C0EC
GO
Isoform 5 (identifier: Q8IW50-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     37-53: Missing.
     134-134: Missing.

Show »
Length:167
Mass (Da):18,428
Checksum:iDF0BBC7B85EE99C1
GO
Isoform 6 (identifier: Q8IW50-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     37-53: Missing.

Show »
Length:168
Mass (Da):18,557
Checksum:i0AF680107AD137EB
GO
Isoform 7 (identifier: Q8IW50-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     115-169: SDDDFDMSRY...DLIPPKSVNP → RCVWGLGGSW...DILQPESLQG
     170-185: Missing.

Show »
Length:157
Mass (Da):17,433
Checksum:i389E604116E36355
GO

Sequence cautioni

The sequence CAI13147.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI13149.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI13151.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI13152.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI13153.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI15969.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI15970.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI15972.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI15973.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI15974.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti123 – 1231R → G in AK123887 (PubMed:14702039).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei10 – 2011Missing in isoform 2, isoform 3 and isoform 4. 2 PublicationsVSP_035492Add
BLAST
Alternative sequencei37 – 5317Missing in isoform 2, isoform 3, isoform 5 and isoform 6. 2 PublicationsVSP_035493Add
BLAST
Alternative sequencei115 – 16955SDDDF…KSVNP → RCVWGLGGSWAAQRNLYSTS GLYRPHLLYCQNWDILQPES LQG in isoform 7. 1 PublicationVSP_035494Add
BLAST
Alternative sequencei134 – 1341Missing in isoform 3, isoform 4 and isoform 5. 2 PublicationsVSP_035496
Alternative sequencei170 – 18516Missing in isoform 7. 1 PublicationVSP_035495Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AI953059 mRNA. No translation available.
AK096350 mRNA. Translation: BAG53270.1.
AK123887 mRNA. No translation available.
AK294054 mRNA. Translation: BAG57402.1.
AK299882 mRNA. Translation: BAG61730.1.
AL160270, AL356494 Genomic DNA. Translation: CAI13147.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13149.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13151.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13152.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13153.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15969.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15970.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15972.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15973.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15974.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAM16095.1.
AL356494, AL160270 Genomic DNA. Translation: CAM22385.1.
CH471071 Genomic DNA. Translation: EAW58454.1.
BC025348 mRNA. Translation: AAH25348.1.
BC041009 mRNA. Translation: AAH41009.1.
CCDSiCCDS55304.1. [Q8IW50-1]
CCDS6556.1. [Q8IW50-6]
RefSeqiNP_001171869.1. NM_001184940.1. [Q8IW50-1]
NP_001171870.1. NM_001184941.1.
NP_001171871.1. NM_001184942.1. [Q8IW50-4]
NP_001171872.1. NM_001184943.1. [Q8IW50-5]
NP_001171874.1. NM_001184945.1. [Q8IW50-3]
NP_671735.1. NM_147202.1. [Q8IW50-6]
UniGeneiHs.493771.

Genome annotation databases

EnsembliENST00000297620; ENSP00000297620; ENSG00000164970. [Q8IW50-6]
ENST00000445726; ENSP00000392452; ENSG00000164970. [Q8IW50-1]
GeneIDi203259.
KEGGihsa:203259.
UCSCiuc003zuj.4. human. [Q8IW50-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AI953059 mRNA. No translation available.
AK096350 mRNA. Translation: BAG53270.1.
AK123887 mRNA. No translation available.
AK294054 mRNA. Translation: BAG57402.1.
AK299882 mRNA. Translation: BAG61730.1.
AL160270, AL356494 Genomic DNA. Translation: CAI13147.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13149.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13151.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13152.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAI13153.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15969.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15970.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15972.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15973.1. Different initiation.
AL356494, AL160270 Genomic DNA. Translation: CAI15974.1. Different initiation.
AL160270, AL356494 Genomic DNA. Translation: CAM16095.1.
AL356494, AL160270 Genomic DNA. Translation: CAM22385.1.
CH471071 Genomic DNA. Translation: EAW58454.1.
BC025348 mRNA. Translation: AAH25348.1.
BC041009 mRNA. Translation: AAH41009.1.
CCDSiCCDS55304.1. [Q8IW50-1]
CCDS6556.1. [Q8IW50-6]
RefSeqiNP_001171869.1. NM_001184940.1. [Q8IW50-1]
NP_001171870.1. NM_001184941.1.
NP_001171871.1. NM_001184942.1. [Q8IW50-4]
NP_001171872.1. NM_001184943.1. [Q8IW50-5]
NP_001171874.1. NM_001184945.1. [Q8IW50-3]
NP_671735.1. NM_147202.1. [Q8IW50-6]
UniGeneiHs.493771.

3D structure databases

ProteinModelPortaliQ8IW50.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128461. 30 interactions.
IntActiQ8IW50. 7 interactions.
MINTiMINT-1369005.

PTM databases

iPTMnetiQ8IW50.
SwissPalmiQ8IW50.

Polymorphism and mutation databases

BioMutaiFAM219A.
DMDMi209572756.

Proteomic databases

MaxQBiQ8IW50.
PaxDbiQ8IW50.
PRIDEiQ8IW50.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000297620; ENSP00000297620; ENSG00000164970. [Q8IW50-6]
ENST00000445726; ENSP00000392452; ENSG00000164970. [Q8IW50-1]
GeneIDi203259.
KEGGihsa:203259.
UCSCiuc003zuj.4. human. [Q8IW50-1]

Organism-specific databases

CTDi203259.
GeneCardsiFAM219A.
H-InvDBHIX0007993.
HGNCiHGNC:19920. FAM219A.
HPAiHPA019338.
HPA052909.
neXtProtiNX_Q8IW50.
PharmGKBiPA134916501.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IVPC. Eukaryota.
ENOG410Y14P. LUCA.
GeneTreeiENSGT00390000000860.
HOVERGENiHBG054822.
InParanoidiQ8IW50.
OMAiSERHAFH.
OrthoDBiEOG7V7689.
PhylomeDBiQ8IW50.
TreeFamiTF331928.

Miscellaneous databases

ChiTaRSiFAM219A. human.
GenomeRNAii203259.
NextBioi90390.
PROiQ8IW50.

Gene expression databases

BgeeiQ8IW50.
CleanExiHS_C9orf25.
ExpressionAtlasiQ8IW50. baseline and differential.
GenevisibleiQ8IW50. HS.

Family and domain databases

InterProiIPR029339. FAM219.
[Graphical view]
PANTHERiPTHR31281. PTHR31281. 1 hit.
PfamiPF15260. FAM219A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. The Cancer Genome Anatomy Project (CGAP) at the National Cancer Institute
    Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 7).
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 4 AND 6).
    Tissue: Brain, Cerebellum and Teratocarcinoma.
  3. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 113-185 (ISOFORM 2).
    Tissue: Brain.
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47; SER-102; THR-113; SER-115 AND SER-122, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-113 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-113 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF219A_HUMAN
AccessioniPrimary (citable) accession number: Q8IW50
Secondary accession number(s): A2A364
, B4DFE1, B4DSR8, Q5T590, Q5T591, Q5T592, Q5T594, Q5T595, Q8TAZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: October 14, 2008
Last modified: March 16, 2016
This is version 97 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.