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Protein
Submitted name:

Exocyst complex component 5

Gene

EXOC5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Exocyst complex component 5Imported
Gene namesi
Name:EXOC5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35619.

PTM / Processingi

Proteomic databases

PaxDbiQ8IW24.
PeptideAtlasiQ8IW24.
PRIDEiQ8IW24.

Expressioni

Gene expression databases

GenevisibleiQ8IW24. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BARD1A0AVN23EBI-10171392,EBI-9977322
BARD1Q997283EBI-10171392,EBI-473181
BRMS1LQ5PSV43EBI-10171392,EBI-5666615
CCDC102BA1A4H13EBI-10171392,EBI-10171570
CCDC67E9PJR55EBI-10171392,EBI-10177066
CCDC67Q05D603EBI-10171392,EBI-748597
DKFZp451B226Q5HYH73EBI-10171392,EBI-10173842
EDRF1Q3B7T1-53EBI-10171392,EBI-10240074
ENO2Q6FHV63EBI-10171392,EBI-10249724
FRMD6Q96NE93EBI-10171392,EBI-741729
HDDC3Q8N4P33EBI-10171392,EBI-750003
KXD1Q9BQD33EBI-10171392,EBI-739657
MAGEA6P433603EBI-10171392,EBI-1045155
OAS1P009733EBI-10171392,EBI-3932815
PTK6Q138823EBI-10171392,EBI-1383632
PYCARDQ9ULZ35EBI-10171392,EBI-751215
RAB14P611063EBI-10171392,EBI-1056404
RAB4AP203383EBI-10171392,EBI-722284
RAB4BP610183EBI-10171392,EBI-10218066
SPACA9Q96E403EBI-10171392,EBI-722584
TNPO2O147873EBI-10171392,EBI-431907
TTC23LQ6PF05-33EBI-10171392,EBI-10182647
TXNL4AP838763EBI-10171392,EBI-746539

Protein-protein interaction databases

IntActiQ8IW24. 23 interactors.
STRINGi9606.ENSP00000389934.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 88Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3745. Eukaryota.
ENOG410XSQQ. LUCA.
HOVERGENiHBG055591.
KOiK19984.

Family and domain databases

InterProiIPR033960. EXOC5/Sec10.
IPR009976. Sec10-like.
[Graphical view]
PANTHERiPTHR12100. PTHR12100. 1 hit.
PTHR12100:SF0. PTHR12100:SF0. 1 hit.
PfamiPF07393. Sec10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IW24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTAELFEE PFVADEYIER LVWRTPGGGS RGGPEAFDPK RLLEEFVNHI
60 70 80 90 100
QELQIMDERI QRKVEKLEQQ CQKEAKEFAK KVQELQKSNQ VAFQHFQELD
110 120 130 140 150
EHISYVATKV CHLGDQLEGV NTPRQRAVEA QKLMKYFNEF LDGELKSDVF
160 170 180 190 200
TNSEKIKEAA DIIQKLHLIA QELPFDRFSE VKSKIASKYH DLECQLIQEF
210 220 230 240 250
TSAQRRGEIS RMREVAAVLL HFKGYSHCVD VYIKQCQEGA YLRNDIFEDA
260 270 280 290 300
GILCQRVNKQ VGDIFSNPET VLAKLIQNVF EIKLQSFVKE QLEECRKSDA
310 320 330 340 350
EQYLKNLYDL YTRTTNLSSK LMEFNLGTDK QTFLSKLIKS IFISYLENYI
360 370 380 390 400
EVETGYLKSR SAMILQRYYD SKNHQKRSIG TGGIQDLKER IRQRTNLPLG
410 420 430 440 450
PSIDTHGETF LSQEVVVNLL QETKQAFERC HRLSDPSDLP RNAFRIFTIL
460 470 480 490 500
VEFLCIEHID YALETGLAGI PSSDSRNANL YFLDVVQQAN TIFHLFDKQF
510 520 530 540 550
NDHLMPLISS SPKLSECLQK KKEIIEQMEM KLDTGIDRTL NCMIRQMKHI
560 570 580 590 600
LAAEQKKTDF KPEDENNVLI QYTNACVKVC AYVRKQVEKI KNSMDGKNVD
610 620 630 640 650
TVLMELGVRF HRLIYEHLQQ YSYSCMGGML AICDVAEYRK CAKDFKIPMV
660 670 680 690 700
LHLFDTLHAL CNLLVVAPDN LKQVCSGEQL ANLDKNILHS FVQLRADYRS

ARLARHFS
Length:708
Mass (Da):81,952
Last modified:March 1, 2003 - v1
Checksum:i8A12AC60C31C62D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC041126 mRNA. Translation: AAH41126.1.
RefSeqiNP_006535.1. NM_006544.3.
UniGeneiHs.743987.

Genome annotation databases

GeneIDi10640.
KEGGihsa:10640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC041126 mRNA. Translation: AAH41126.1.
RefSeqiNP_006535.1. NM_006544.3.
UniGeneiHs.743987.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IW24. 23 interactors.
STRINGi9606.ENSP00000389934.

Proteomic databases

PaxDbiQ8IW24.
PeptideAtlasiQ8IW24.
PRIDEiQ8IW24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10640.
KEGGihsa:10640.

Organism-specific databases

CTDi10640.
PharmGKBiPA35619.

Phylogenomic databases

eggNOGiKOG3745. Eukaryota.
ENOG410XSQQ. LUCA.
HOVERGENiHBG055591.
KOiK19984.

Miscellaneous databases

ChiTaRSiEXOC5. human.
GenomeRNAii10640.

Gene expression databases

GenevisibleiQ8IW24. HS.

Family and domain databases

InterProiIPR033960. EXOC5/Sec10.
IPR009976. Sec10-like.
[Graphical view]
PANTHERiPTHR12100. PTHR12100. 1 hit.
PTHR12100:SF0. PTHR12100:SF0. 1 hit.
PfamiPF07393. Sec10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IW24_HUMAN
AccessioniPrimary (citable) accession number: Q8IW24
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.