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Protein

Ciliary-associated calcium-binding coiled-coil protein 1

Gene

CABCOCO1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Calcium-binding protein. May be involved in the control of sperm flagellar movement.By similarity

GO - Molecular functioni

Keywordsi

LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ciliary-associated calcium-binding coiled-coil protein 1Imported
Gene namesi
Name:CABCOCO1Imported
Synonyms:C10orf107Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000183346.6.
HGNCiHGNC:28678. CABCOCO1.
neXtProtiNX_Q8IVU9.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Flagellum

Pathology & Biotechi

Organism-specific databases

DisGeNETi219621.
OpenTargetsiENSG00000183346.
PharmGKBiPA134897916.

Polymorphism and mutation databases

BioMutaiC10orf107.
DMDMi71152994.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898191 – 208Ciliary-associated calcium-binding coiled-coil protein 1Add BLAST208

Proteomic databases

PaxDbiQ8IVU9.
PeptideAtlasiQ8IVU9.
PRIDEiQ8IVU9.

PTM databases

iPTMnetiQ8IVU9.
PhosphoSitePlusiQ8IVU9.

Expressioni

Gene expression databases

BgeeiENSG00000183346.
CleanExiHS_C10orf107.
ExpressionAtlasiQ8IVU9. baseline and differential.
GenevisibleiQ8IVU9. HS.

Organism-specific databases

HPAiHPA041398.

Interactioni

Protein-protein interaction databases

BioGridi128558. 4 interactors.
STRINGi9606.ENSP00000328698.

Structurei

3D structure databases

ProteinModelPortaliQ8IVU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IK9I. Eukaryota.
ENOG411297J. LUCA.
GeneTreeiENSGT00390000004181.
HOGENOMiHOG000111703.
HOVERGENiHBG081196.
InParanoidiQ8IVU9.
OMAiIQEEAFN.
OrthoDBiEOG091G0WDJ.
PhylomeDBiQ8IVU9.
TreeFamiTF329043.

Family and domain databases

InterProiView protein in InterPro
IPR032727. CLAMP.
PfamiView protein in Pfam
PF14769. CLAMP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IVU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSIIQYSK FMTLLAMSLQ NLKTLHMSLE ESIKWLGEVM AEIGPTHSQK
60 70 80 90 100
SEDWNIFDVK QANAIIDYLK ISLFQHYKLY EFMFYSAREE IVIGTEQVIE
110 120 130 140 150
VVKSACGPFP NPLEEGISFD IYSTFIEPPT ILDTEMKRLD QEQGPEESQP
160 170 180 190 200
ETDTSDMDPL VGFTIEDVKS VLDQVTDDIL IGIQTEINEK LQIQEEAFNA

RIEKLKKA
Length:208
Mass (Da):23,883
Last modified:March 1, 2003 - v1
Checksum:iBA44BF4E2742753C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL451049, AC022398 Genomic DNA. Translation: CAI16227.2.
BC041932 mRNA. Translation: AAH41932.1.
CCDSiCCDS7262.1.
RefSeqiNP_775825.1. NM_173554.2.
XP_005269657.1. XM_005269600.4.
UniGeneiHs.673160.

Genome annotation databases

EnsembliENST00000330194; ENSP00000328698; ENSG00000183346.
GeneIDi219621.
KEGGihsa:219621.
UCSCiuc010qik.3. human.

Similar proteinsi

Entry informationi

Entry nameiCBCO1_HUMAN
AccessioniPrimary (citable) accession number: Q8IVU9
Secondary accession number(s): Q5T1B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2003
Last modified: January 31, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM