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Protein

Ciliary-associated calcium-binding coiled-coil protein 1

Gene

CABCOCO1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Calcium-binding protein. May be involved in the control of sperm flagellar movement.By similarity

GO - Molecular functioni

Keywordsi

LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ciliary-associated calcium-binding coiled-coil protein 1Imported
Gene namesi
Name:CABCOCO1Imported
Synonyms:C10orf107Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000183346.6
HGNCiHGNC:28678 CABCOCO1
neXtProtiNX_Q8IVU9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Flagellum

Pathology & Biotechi

Organism-specific databases

DisGeNETi219621
OpenTargetsiENSG00000183346
PharmGKBiPA134897916

Polymorphism and mutation databases

BioMutaiC10orf107
DMDMi71152994

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898191 – 208Ciliary-associated calcium-binding coiled-coil protein 1Add BLAST208

Proteomic databases

PaxDbiQ8IVU9
PeptideAtlasiQ8IVU9
PRIDEiQ8IVU9
ProteomicsDBi70773

PTM databases

iPTMnetiQ8IVU9
PhosphoSitePlusiQ8IVU9

Expressioni

Gene expression databases

BgeeiENSG00000183346
CleanExiHS_C10orf107
ExpressionAtlasiQ8IVU9 baseline and differential
GenevisibleiQ8IVU9 HS

Organism-specific databases

HPAiHPA041398

Interactioni

Protein-protein interaction databases

BioGridi128558, 4 interactors
STRINGi9606.ENSP00000328698

Structurei

3D structure databases

ProteinModelPortaliQ8IVU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IK9I Eukaryota
ENOG411297J LUCA
GeneTreeiENSGT00390000004181
HOGENOMiHOG000111703
HOVERGENiHBG081196
InParanoidiQ8IVU9
OMAiIQEEAFN
OrthoDBiEOG091G0WDJ
PhylomeDBiQ8IVU9
TreeFamiTF329043

Family and domain databases

InterProiView protein in InterPro
IPR032727 CLAMP
PfamiView protein in Pfam
PF14769 CLAMP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IVU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSIIQYSK FMTLLAMSLQ NLKTLHMSLE ESIKWLGEVM AEIGPTHSQK
60 70 80 90 100
SEDWNIFDVK QANAIIDYLK ISLFQHYKLY EFMFYSAREE IVIGTEQVIE
110 120 130 140 150
VVKSACGPFP NPLEEGISFD IYSTFIEPPT ILDTEMKRLD QEQGPEESQP
160 170 180 190 200
ETDTSDMDPL VGFTIEDVKS VLDQVTDDIL IGIQTEINEK LQIQEEAFNA

RIEKLKKA
Length:208
Mass (Da):23,883
Last modified:March 1, 2003 - v1
Checksum:iBA44BF4E2742753C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022398 Genomic DNA No translation available.
AL451049 Genomic DNA No translation available.
BC041932 mRNA Translation: AAH41932.1
CCDSiCCDS7262.1
RefSeqiNP_775825.1, NM_173554.2
XP_005269657.1, XM_005269600.4
UniGeneiHs.673160

Genome annotation databases

EnsembliENST00000330194; ENSP00000328698; ENSG00000183346
GeneIDi219621
KEGGihsa:219621
UCSCiuc010qik.3 human

Similar proteinsi

Entry informationi

Entry nameiCBCO1_HUMAN
AccessioniPrimary (citable) accession number: Q8IVU9
Secondary accession number(s): Q5T1B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2003
Last modified: June 20, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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