Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Musculoskeletal embryonic nuclear protein 1

Gene

MUSTN1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in the development and regeneration of the musculoskeletal system.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Musculoskeletal embryonic nuclear protein 1
Gene namesi
Name:MUSTN1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:22144. MUSTN1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134991411.

Polymorphism and mutation databases

BioMutaiMUSTN1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8282Musculoskeletal embryonic nuclear protein 1PRO_0000299447Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8IVN3.
PeptideAtlasiQ8IVN3.
PRIDEiQ8IVN3.

PTM databases

iPTMnetiQ8IVN3.
PhosphoSiteiQ8IVN3.

Expressioni

Gene expression databases

BgeeiENSG00000272573.
CleanExiHS_MUSTN1.
ExpressionAtlasiQ8IVN3. baseline and differential.
GenevisibleiQ8IVN3. HS.

Interactioni

Protein-protein interaction databases

BioGridi132988. 1 interaction.
STRINGi9606.ENSP00000410910.

Structurei

3D structure databases

ProteinModelPortaliQ8IVN3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi10 – 189Nuclear localization signalSequence analysis

Sequence similaritiesi

Belongs to the MUSTANG family.Curated

Phylogenomic databases

eggNOGiENOG410J3H4. Eukaryota.
ENOG410YWMF. LUCA.
GeneTreeiENSGT00610000086298.
HOGENOMiHOG000035100.
HOVERGENiHBG107346.
InParanoidiQ8IVN3.
PhylomeDBiQ8IVN3.
TreeFamiTF330732.

Family and domain databases

InterProiIPR031394. MUSTN1.
[Graphical view]
PfamiPF15682. Mustang. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IVN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQAGAQEAP IKKKRPPVKD EDLKGARGNL TKNQEIKSKT YQVMRECEQA
60 70 80
GSAAPSVFSR TRTGTETVFE KPKAGPTKSV FG
Length:82
Mass (Da):8,911
Last modified:May 18, 2010 - v2
Checksum:i29FB236077227DC8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti20 – 201D → E in CAC81756 (Ref. 1) Curated
Sequence conflicti20 – 201D → E in AAI30551 (PubMed:15489334).Curated
Sequence conflicti20 – 201D → E in AAI30553 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ276556 mRNA. Translation: CAC81756.1.
AC099667 Genomic DNA. No translation available.
BC130550 mRNA. Translation: AAI30551.1.
BC130552 mRNA. Translation: AAI30553.1.
CCDSiCCDS46846.1.
RefSeqiNP_995325.3. NM_205853.3.
UniGeneiHs.556077.

Genome annotation databases

EnsembliENST00000446157; ENSP00000410910; ENSG00000272573.
GeneIDi389125.
KEGGihsa:389125.
UCSCiuc003dga.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ276556 mRNA. Translation: CAC81756.1.
AC099667 Genomic DNA. No translation available.
BC130550 mRNA. Translation: AAI30551.1.
BC130552 mRNA. Translation: AAI30553.1.
CCDSiCCDS46846.1.
RefSeqiNP_995325.3. NM_205853.3.
UniGeneiHs.556077.

3D structure databases

ProteinModelPortaliQ8IVN3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi132988. 1 interaction.
STRINGi9606.ENSP00000410910.

PTM databases

iPTMnetiQ8IVN3.
PhosphoSiteiQ8IVN3.

Polymorphism and mutation databases

BioMutaiMUSTN1.

Proteomic databases

PaxDbiQ8IVN3.
PeptideAtlasiQ8IVN3.
PRIDEiQ8IVN3.

Protocols and materials databases

DNASUi389125.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000446157; ENSP00000410910; ENSG00000272573.
GeneIDi389125.
KEGGihsa:389125.
UCSCiuc003dga.5. human.

Organism-specific databases

CTDi389125.
GeneCardsiMUSTN1.
HGNCiHGNC:22144. MUSTN1.
neXtProtiNX_Q8IVN3.
PharmGKBiPA134991411.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J3H4. Eukaryota.
ENOG410YWMF. LUCA.
GeneTreeiENSGT00610000086298.
HOGENOMiHOG000035100.
HOVERGENiHBG107346.
InParanoidiQ8IVN3.
PhylomeDBiQ8IVN3.
TreeFamiTF330732.

Miscellaneous databases

GenomeRNAii389125.
PROiQ8IVN3.

Gene expression databases

BgeeiENSG00000272573.
CleanExiHS_MUSTN1.
ExpressionAtlasiQ8IVN3. baseline and differential.
GenevisibleiQ8IVN3. HS.

Family and domain databases

InterProiIPR031394. MUSTN1.
[Graphical view]
PfamiPF15682. Mustang. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMSTN1_HUMAN
AccessioniPrimary (citable) accession number: Q8IVN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 18, 2010
Last modified: September 7, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.