Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8IV92

- Q8IV92_HUMAN

UniProt

Q8IV92 - Q8IV92_HUMAN

Protein
Submitted name:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene

PLCB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. phosphatidylinositol phospholipase C activity Source: InterPro

    GO - Biological processi

    1. brain development Source: InterPro
    2. intracellular signal transduction Source: InterPro
    3. regulation of cell cycle Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1Imported
    Gene namesi
    Name:PLCB1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 20

    Organism-specific databases

    HGNCiHGNC:15917. PLCB1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro
    2. nucleus Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8IV92.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8IV92.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IV92.
    SMRiQ8IV92. Positions 1-152.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 C2 domain.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000202437.
    OMAiINNTIAF.

    Family and domain databases

    Gene3Di2.60.40.150. 1 hit.
    InterProiIPR000008. C2_dom.
    IPR001192. PI-PLC_fam.
    IPR028400. PLC-beta1.
    [Graphical view]
    PANTHERiPTHR10336. PTHR10336. 1 hit.
    PTHR10336:SF12. PTHR10336:SF12. 1 hit.
    PfamiPF00168. C2. 1 hit.
    [Graphical view]
    SMARTiSM00239. C2. 1 hit.
    [Graphical view]
    SUPFAMiSSF49562. SSF49562. 1 hit.
    PROSITEiPS50004. C2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8IV92-1 [UniParc]FASTAAdd to Basket

    « Hide

    IISGQFLSDK KVGTYVEVDM FGLPVDTRRK AFKTKTSQGN AVNPVWEEEP    50
    IVFKKVVLPT LACLRIAVYE EGGKFIGHRI LPVQAIRPGY HYICLRNERN 100
    QPLTLPAVFV YIEVKDYVPD TYADVIEALS NPIRYVNLME QRAKQLAALT 150
    LEDEEEVKKE GGFLHDEIMR LTRNTLEKLM ALPLTHVVPI QSKMLS 196
    Length:196
    Mass (Da):22,328
    Last modified:March 1, 2003 - v1
    Checksum:iE76782BE3DD52E1A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021406 Genomic DNA. No translation available.
    AL031655 Genomic DNA. No translation available.
    AL031683 Genomic DNA. No translation available.
    AL034551 Genomic DNA. No translation available.
    AL049593 Genomic DNA. No translation available.
    AL049632 Genomic DNA. No translation available.
    AL050315 Genomic DNA. No translation available.
    AL050319 Genomic DNA. No translation available.
    AL050323 Genomic DNA. No translation available.
    AL121589 Genomic DNA. No translation available.
    AL365212 Genomic DNA. No translation available.
    AL445567 Genomic DNA. No translation available.
    KF456806 Genomic DNA. No translation available.
    KF456807 Genomic DNA. No translation available.
    KF456810 Genomic DNA. No translation available.
    KF456814 Genomic DNA. No translation available.
    KF456816 Genomic DNA. No translation available.
    KF510482 Genomic DNA. No translation available.
    KF511324 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000439627; ENSP00000391162; ENSG00000182621.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL021406 Genomic DNA. No translation available.
    AL031655 Genomic DNA. No translation available.
    AL031683 Genomic DNA. No translation available.
    AL034551 Genomic DNA. No translation available.
    AL049593 Genomic DNA. No translation available.
    AL049632 Genomic DNA. No translation available.
    AL050315 Genomic DNA. No translation available.
    AL050319 Genomic DNA. No translation available.
    AL050323 Genomic DNA. No translation available.
    AL121589 Genomic DNA. No translation available.
    AL365212 Genomic DNA. No translation available.
    AL445567 Genomic DNA. No translation available.
    KF456806 Genomic DNA. No translation available.
    KF456807 Genomic DNA. No translation available.
    KF456810 Genomic DNA. No translation available.
    KF456814 Genomic DNA. No translation available.
    KF456816 Genomic DNA. No translation available.
    KF510482 Genomic DNA. No translation available.
    KF511324 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali Q8IV92.
    SMRi Q8IV92. Positions 1-152.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8IV92.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000439627 ; ENSP00000391162 ; ENSG00000182621 .

    Organism-specific databases

    HGNCi HGNC:15917. PLCB1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000202437.
    OMAi INNTIAF.

    Miscellaneous databases

    ChiTaRSi PLCB1. human.

    Gene expression databases

    ArrayExpressi Q8IV92.

    Family and domain databases

    Gene3Di 2.60.40.150. 1 hit.
    InterProi IPR000008. C2_dom.
    IPR001192. PI-PLC_fam.
    IPR028400. PLC-beta1.
    [Graphical view ]
    PANTHERi PTHR10336. PTHR10336. 1 hit.
    PTHR10336:SF12. PTHR10336:SF12. 1 hit.
    Pfami PF00168. C2. 1 hit.
    [Graphical view ]
    SMARTi SM00239. C2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49562. SSF49562. 1 hit.
    PROSITEi PS50004. C2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiQ8IV92_HUMAN
    AccessioniPrimary (citable) accession number: Q8IV92
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3