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Protein
Submitted name:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene

PLCB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1Imported
Gene namesi
Name:PLCB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000182621.16.
HGNCiHGNC:15917. PLCB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182621.

PTM / Processingi

Proteomic databases

MaxQBiQ8IV92.
PaxDbiQ8IV92.
PeptideAtlasiQ8IV92.
PRIDEiQ8IV92.

Expressioni

Gene expression databases

BgeeiENSG00000182621.
ExpressionAtlasiQ8IV92. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ8IV92.
SMRiQ8IV92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 80C2InterPro annotationAdd BLAST80

Phylogenomic databases

eggNOGiKOG0169. Eukaryota.
ENOG410XPSW. LUCA.
GeneTreeiENSGT00760000118936.
HOGENOMiHOG000202437.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiView protein in InterPro
IPR000008. C2_dom.
IPR001192. PI-PLC_fam.
IPR028400. PLC-beta1.
PANTHERiPTHR10336. PTHR10336. 1 hit.
PTHR10336:SF108. PTHR10336:SF108. 1 hit.
PfamiView protein in Pfam
PF00168. C2. 1 hit.
SMARTiView protein in SMART
SM00239. C2. 1 hit.
SUPFAMiSSF49562. SSF49562. 1 hit.
PROSITEiView protein in PROSITE
PS50004. C2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8IV92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IISGQFLSDK KVGTYVEVDM FGLPVDTRRK AFKTKTSQGN AVNPVWEEEP
60 70 80 90 100
IVFKKVVLPT LACLRIAVYE EGGKFIGHRI LPVQAIRPGY HYICLRNERN
110 120 130 140 150
QPLTLPAVFV YIEVKDYVPD TYADVIEALS NPIRYVNLME QRAKQLAALT
160 170 180 190
LEDEEEVKKE GGFLHDEIMR LTRNTLEKLM ALPLTHVVPI QSKMLS
Length:196
Mass (Da):22,328
Last modified:March 1, 2003 - v1
Checksum:iE76782BE3DD52E1A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021396 Genomic DNA. No translation available.
AL021406 Genomic DNA. No translation available.
AL050323 Genomic DNA. No translation available.
KF456806 Genomic DNA. No translation available.
KF456810 Genomic DNA. No translation available.
KF510482 Genomic DNA. No translation available.
KF511324 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000439627; ENSP00000391162; ENSG00000182621.
UCSCiuc061vik.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ8IV92_HUMAN
AccessioniPrimary (citable) accession number: Q8IV92
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 27, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported