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Protein
Submitted name:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene

PLCB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1Imported
Gene namesi
Name:PLCB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000182621.16
HGNCiHGNC:15917 PLCB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182621

PTM / Processingi

Proteomic databases

MaxQBiQ8IV92
PeptideAtlasiQ8IV92
PRIDEiQ8IV92

Expressioni

Gene expression databases

BgeeiENSG00000182621
ExpressionAtlasiQ8IV92 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ8IV92
SMRiQ8IV92
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 80C2InterPro annotationAdd BLAST80

Phylogenomic databases

eggNOGiKOG0169 Eukaryota
ENOG410XPSW LUCA
GeneTreeiENSGT00760000118936
HOGENOMiHOG000202437

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001192 PI-PLC_fam
IPR028400 PLC-beta1
PANTHERiPTHR10336 PTHR10336, 1 hit
PTHR10336:SF12 PTHR10336:SF12, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q8IV92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IISGQFLSDK KVGTYVEVDM FGLPVDTRRK AFKTKTSQGN AVNPVWEEEP
60 70 80 90 100
IVFKKVVLPT LACLRIAVYE EGGKFIGHRI LPVQAIRPGY HYICLRNERN
110 120 130 140 150
QPLTLPAVFV YIEVKDYVPD TYADVIEALS NPIRYVNLME QRAKQLAALT
160 170 180 190
LEDEEEVKKE GGFLHDEIMR LTRNTLEKLM ALPLTHVVPI QSKMLS
Length:196
Mass (Da):22,328
Last modified:March 1, 2003 - v1
Checksum:iE76782BE3DD52E1A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021396 Genomic DNA No translation available.
AL021406 Genomic DNA No translation available.
AL050323 Genomic DNA No translation available.
KF456806 Genomic DNA No translation available.
KF456810 Genomic DNA No translation available.
KF510482 Genomic DNA No translation available.
KF511324 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000439627; ENSP00000391162; ENSG00000182621
UCSCiuc061vik.1 human

Similar proteinsi

Entry informationi

Entry nameiQ8IV92_HUMAN
AccessioniPrimary (citable) accession number: Q8IV92
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health