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Protein
Submitted name:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene

PLCB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1Imported
Gene namesi
Name:PLCB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000182621.16
HGNCiHGNC:15917 PLCB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182621

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8IV91
PRIDEiQ8IV91

Expressioni

Gene expression databases

BgeeiENSG00000182621
ExpressionAtlasiQ8IV91 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ8IV91
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 40PLC-beta_CInterPro annotationAdd BLAST40

Phylogenomic databases

eggNOGiKOG0169 Eukaryota
ENOG410XPSW LUCA
GeneTreeiENSGT00760000118936

Family and domain databases

InterProiView protein in InterPro
IPR001192 PI-PLC_fam
IPR028400 PLC-beta1
IPR014815 PLC-beta_C
PANTHERiPTHR10336 PTHR10336, 1 hit
PTHR10336:SF12 PTHR10336:SF12, 1 hit
PfamiView protein in Pfam
PF08703 PLC-beta_C, 1 hit

Sequencei

Sequence statusi: Fragment.

Q8IV91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
IQEVVQYIKR LEEAQSKRQE KLVEKHKEIR QQILDEKPKV P
Length:41
Mass (Da):5,013
Last modified:May 27, 2015 - v2
Checksum:iF1BC0F42D68842FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021396 Genomic DNA No translation available.
AL021406 Genomic DNA No translation available.
AL050323 Genomic DNA No translation available.
KF456806 Genomic DNA No translation available.
KF456810 Genomic DNA No translation available.
KF510482 Genomic DNA No translation available.
KF511324 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000437439; ENSP00000389911; ENSG00000182621
UCSCiuc061vim.1 human

Similar proteinsi

Entry informationi

Entry nameiQ8IV91_HUMAN
AccessioniPrimary (citable) accession number: Q8IV91
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: May 27, 2015
Last modified: March 28, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health