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Q8IUX7

- AEBP1_HUMAN

UniProt

Q8IUX7 - AEBP1_HUMAN

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Protein

Adipocyte enhancer-binding protein 1

Gene

AEBP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.By similarity

GO - Molecular functioni

  1. carboxypeptidase activity Source: ProtInc
  2. metallocarboxypeptidase activity Source: InterPro
  3. RNA polymerase II regulatory region sequence-specific DNA binding Source: NTNU_SB
  4. RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: NTNU_SB
  5. sequence-specific DNA binding transcription factor activity Source: ProtInc
  6. transcription corepressor activity Source: Ensembl
  7. zinc ion binding Source: InterPro

GO - Biological processi

  1. cell adhesion Source: InterPro
  2. muscle organ development Source: ProtInc
  3. negative regulation of transcription from RNA polymerase II promoter Source: NTNU_SB
  4. skeletal system development Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Calmodulin-binding, DNA-binding

Protein family/group databases

MEROPSiM14.951.

Names & Taxonomyi

Protein namesi
Recommended name:
Adipocyte enhancer-binding protein 1
Short name:
AE-binding protein 1
Alternative name(s):
Aortic carboxypeptidase-like protein
Gene namesi
Name:AEBP1
Synonyms:ACLP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:303. AEBP1.

Subcellular locationi

Isoform 1 : Secreted By similarity
Isoform 2 : Cytoplasm Curated. Nucleus Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. extracellular space Source: BHF-UCL
  3. extracellular vesicular exosome Source: UniProt
  4. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus, Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24604.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 11581133Adipocyte enhancer-binding protein 1PRO_0000333189Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi528 – 5281N-linked (GlcNAc...)1 Publication
Glycosylationi922 – 9221N-linked (GlcNAc...)1 Publication

Post-translational modificationi

Phosphorylated by MAPK1 in vitro.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ8IUX7.
PaxDbiQ8IUX7.
PRIDEiQ8IUX7.

PTM databases

PhosphoSiteiQ8IUX7.

Expressioni

Tissue specificityi

Expressed in osteoblast and visceral fat.1 Publication

Gene expression databases

BgeeiQ8IUX7.
CleanExiHS_AEBP1.
ExpressionAtlasiQ8IUX7. baseline and differential.
GenevestigatoriQ8IUX7.

Organism-specific databases

HPAiCAB009966.

Interactioni

Subunit structurei

Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro.By similarity

Protein-protein interaction databases

BioGridi106674. 1 interaction.
IntActiQ8IUX7. 2 interactions.
MINTiMINT-7034542.
STRINGi9606.ENSP00000223357.

Structurei

3D structure databases

ProteinModelPortaliQ8IUX7.
SMRiQ8IUX7. Positions 387-542, 560-1018.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini383 – 540158F5/8 type CPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni390 – 555166Required for DNA-binding and interaction with NFKBIABy similarityAdd
BLAST
Regioni421 – 624204Interaction with MAPK1 and MAPK3By similarityAdd
BLAST
Regioni555 – 985431Interaction with PTENBy similarityAdd
BLAST
Regioni941 – 1158218Required for transcriptional repressionBy similarityAdd
BLAST
Regioni1006 – 1158153Interaction with MAPK1 and MAPK3By similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi47 – 326280Pro-richAdd
BLAST
Compositional biasi1079 – 113658Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase M14 family.Curated
Contains 1 F5/8 type C domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG292169.
GeneTreeiENSGT00760000119124.
HOGENOMiHOG000232185.
HOVERGENiHBG003410.
InParanoidiQ8IUX7.
OMAiLDYNDQI.
OrthoDBiEOG7B8S32.
PhylomeDBiQ8IUX7.
TreeFamiTF315592.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.1120. 1 hit.
InterProiIPR008969. CarboxyPept-like_regulatory.
IPR014766. CarboxyPept_regulatory_dom.
IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR008979. Galactose-bd-like.
IPR000834. Peptidase_M14.
[Graphical view]
PfamiPF00754. F5_F8_type_C. 1 hit.
PF00246. Peptidase_M14. 1 hit.
[Graphical view]
PRINTSiPR00765. CRBOXYPTASEA.
SMARTiSM00231. FA58C. 1 hit.
SM00631. Zn_pept. 1 hit.
[Graphical view]
SUPFAMiSSF49464. SSF49464. 1 hit.
SSF49785. SSF49785. 1 hit.
PROSITEiPS00132. CARBOXYPEPT_ZN_1. 1 hit.
PS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8IUX7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAAVRGAPLL SCLLALLALC PGGRPQTVLT DDEIEEFLEG FLSELEPEPR
60 70 80 90 100
EDDVEAPPPP EPTPRVRKAQ AGGKPGKRPG TAAEVPPEKT KDKGKKGKKD
110 120 130 140 150
KGPKVPKESL EGSPRPPKKG KEKPPKATKK PKEKPPKATK KPKEKPPKAT
160 170 180 190 200
KKPKEKPPKA TKKPPSGKRP PILAPSETLE WPLPPPPSPG PEELPQEGGA
210 220 230 240 250
PLSNNWQNPG EETHVEAREH QPEPEEETEQ PTLDYNDQIE REDYEDFEYI
260 270 280 290 300
RRQKQPRPPP SRRRRPERVW PEPPEEKAPA PAPEERIEPP VKPLLPPLPP
310 320 330 340 350
DYGDGYVIPN YDDMDYYFGP PPPQKPDAER QTDEEKEELK KPKKEDSSPK
360 370 380 390 400
EETDKWAVEK GKDHKEPRKG EELEEEWTPT EKVKCPPIGM ESHRIEDNQI
410 420 430 440 450
RASSMLRHGL GAQRGRLNMQ TGATEDDYYD GAWCAEDDAR TQWIEVDTRR
460 470 480 490 500
TTRFTGVITQ GRDSSIHDDF VTTFFVGFSN DSQTWVMYTN GYEEMTFHGN
510 520 530 540 550
VDKDTPVLSE LPEPVVARFI RIYPLTWNGS LCMRLEVLGC SVAPVYSYYA
560 570 580 590 600
QNEVVATDDL DFRHHSYKDM RQLMKVVNEE CPTITRTYSL GKSSRGLKIY
610 620 630 640 650
AMEISDNPGE HELGEPEFRY TAGIHGNEVL GRELLLLLMQ YLCREYRDGN
660 670 680 690 700
PRVRSLVQDT RIHLVPSLNP DGYEVAAQMG SEFGNWALGL WTEEGFDIFE
710 720 730 740 750
DFPDLNSVLW GAEERKWVPY RVPNNNLPIP ERYLSPDATV STEVRAIIAW
760 770 780 790 800
MEKNPFVLGA NLNGGERLVS YPYDMARTPT QEQLLAAAMA AARGEDEDEV
810 820 830 840 850
SEAQETPDHA IFRWLAISFA SAHLTLTEPY RGGCQAQDYT GGMGIVNGAK
860 870 880 890 900
WNPRTGTIND FSYLHTNCLE LSFYLGCDKF PHESELPREW ENNKEALLTF
910 920 930 940 950
MEQVHRGIKG VVTDEQGIPI ANATISVSGI NHGVKTASGG DYWRILNPGE
960 970 980 990 1000
YRVTAHAEGY TPSAKTCNVD YDIGATQCNF ILARSNWKRI REIMAMNGNR
1010 1020 1030 1040 1050
PIPHIDPSRP MTPQQRRLQQ RRLQHRLRLR AQMRLRRLNA TTTLGPHTVP
1060 1070 1080 1090 1100
PTLPPAPATT LSTTIEPWGL IPPTTAGWEE SETETYTEVV TEFGTEVEPE
1110 1120 1130 1140 1150
FGTKVEPEFE TQLEPEFETQ LEPEFEEEEE EEKEEEIATG QAFPFTTVET

YTVNFGDF
Length:1,158
Mass (Da):130,929
Last modified:March 1, 2003 - v1
Checksum:i1D7F4A20451646AE
GO
Isoform 2 (identifier: Q8IUX7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-457: Missing.
     458-495: ITQGRDSSIH...VMYTNGYEEM → MRKWWAPCPG...STALRPASPQ
     543-544: AP → ARECGGLAGALSGGGVLGWASRHPAKDNPASLAA

Note: No experimental confirmation available.

Show »
Length:733
Mass (Da):82,183
Checksum:iA749B43E37811E45
GO

Sequence cautioni

The sequence BAD92981.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti145 – 1451K → E in AAC25585. (PubMed:9624159)Curated
Sequence conflicti218 – 2181R → Q in AAC25585. (PubMed:9624159)Curated
Sequence conflicti569 – 5691D → G in BAC87026. (PubMed:14702039)Curated
Sequence conflicti715 – 7151R → G in BAC87026. (PubMed:14702039)Curated
Sequence conflicti884 – 8841S → G in BAC87026. (PubMed:14702039)Curated
Sequence conflicti1079 – 10791E → G in BAD92981. 1 PublicationCurated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti273 – 2731P → T.
Corresponds to variant rs2537188 [ dbSNP | Ensembl ].
VAR_043118
Natural varianti648 – 6481D → E.
Corresponds to variant rs11770649 [ dbSNP | Ensembl ].
VAR_043119
Natural varianti1001 – 10011P → L.
Corresponds to variant rs4724285 [ dbSNP | Ensembl ].
VAR_043120
Natural varianti1133 – 11331K → E.1 Publication
Corresponds to variant rs13928 [ dbSNP | Ensembl ].
VAR_043121
Natural varianti1148 – 11481V → I.
Corresponds to variant rs13898 [ dbSNP | Ensembl ].
VAR_043122

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 457457Missing in isoform 2. 1 PublicationVSP_033467Add
BLAST
Alternative sequencei458 – 49538ITQGR…GYEEM → MRKWWAPCPGSWLCSHCLGE GWALRGAGSTALRPASPQ in isoform 2. 1 PublicationVSP_033468Add
BLAST
Alternative sequencei543 – 5442AP → ARECGGLAGALSGGGVLGWA SRHPAKDNPASLAA in isoform 2. 1 PublicationVSP_033469

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF053944 mRNA. Translation: AAC25585.1.
AK127541 mRNA. Translation: BAC87026.1.
AB209744 mRNA. Translation: BAD92981.1. Different initiation.
CH236960 Genomic DNA. Translation: EAL23768.1.
CH471128 Genomic DNA. Translation: EAW61119.1.
BC038588 mRNA. Translation: AAH38588.1.
D86479 mRNA. Translation: BAA13094.1.
CCDSiCCDS5476.1. [Q8IUX7-1]
PIRiJC5256.
RefSeqiNP_001120.3. NM_001129.4. [Q8IUX7-1]
UniGeneiHs.439463.

Genome annotation databases

EnsembliENST00000223357; ENSP00000223357; ENSG00000106624. [Q8IUX7-1]
ENST00000450684; ENSP00000398878; ENSG00000106624. [Q8IUX7-2]
GeneIDi165.
KEGGihsa:165.
UCSCiuc003tkb.4. human. [Q8IUX7-1]
uc003tkc.5. human. [Q8IUX7-2]

Polymorphism databases

DMDMi74728002.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF053944 mRNA. Translation: AAC25585.1 .
AK127541 mRNA. Translation: BAC87026.1 .
AB209744 mRNA. Translation: BAD92981.1 . Different initiation.
CH236960 Genomic DNA. Translation: EAL23768.1 .
CH471128 Genomic DNA. Translation: EAW61119.1 .
BC038588 mRNA. Translation: AAH38588.1 .
D86479 mRNA. Translation: BAA13094.1 .
CCDSi CCDS5476.1. [Q8IUX7-1 ]
PIRi JC5256.
RefSeqi NP_001120.3. NM_001129.4. [Q8IUX7-1 ]
UniGenei Hs.439463.

3D structure databases

ProteinModelPortali Q8IUX7.
SMRi Q8IUX7. Positions 387-542, 560-1018.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 106674. 1 interaction.
IntActi Q8IUX7. 2 interactions.
MINTi MINT-7034542.
STRINGi 9606.ENSP00000223357.

Protein family/group databases

MEROPSi M14.951.

PTM databases

PhosphoSitei Q8IUX7.

Polymorphism databases

DMDMi 74728002.

Proteomic databases

MaxQBi Q8IUX7.
PaxDbi Q8IUX7.
PRIDEi Q8IUX7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000223357 ; ENSP00000223357 ; ENSG00000106624 . [Q8IUX7-1 ]
ENST00000450684 ; ENSP00000398878 ; ENSG00000106624 . [Q8IUX7-2 ]
GeneIDi 165.
KEGGi hsa:165.
UCSCi uc003tkb.4. human. [Q8IUX7-1 ]
uc003tkc.5. human. [Q8IUX7-2 ]

Organism-specific databases

CTDi 165.
GeneCardsi GC07P044143.
HGNCi HGNC:303. AEBP1.
HPAi CAB009966.
MIMi 602981. gene.
neXtProti NX_Q8IUX7.
PharmGKBi PA24604.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG292169.
GeneTreei ENSGT00760000119124.
HOGENOMi HOG000232185.
HOVERGENi HBG003410.
InParanoidi Q8IUX7.
OMAi LDYNDQI.
OrthoDBi EOG7B8S32.
PhylomeDBi Q8IUX7.
TreeFami TF315592.

Miscellaneous databases

ChiTaRSi AEBP1. human.
GenomeRNAii 165.
NextBioi 665.
PROi Q8IUX7.
SOURCEi Search...

Gene expression databases

Bgeei Q8IUX7.
CleanExi HS_AEBP1.
ExpressionAtlasi Q8IUX7. baseline and differential.
Genevestigatori Q8IUX7.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.1120. 1 hit.
InterProi IPR008969. CarboxyPept-like_regulatory.
IPR014766. CarboxyPept_regulatory_dom.
IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR008979. Galactose-bd-like.
IPR000834. Peptidase_M14.
[Graphical view ]
Pfami PF00754. F5_F8_type_C. 1 hit.
PF00246. Peptidase_M14. 1 hit.
[Graphical view ]
PRINTSi PR00765. CRBOXYPTASEA.
SMARTi SM00231. FA58C. 1 hit.
SM00631. Zn_pept. 1 hit.
[Graphical view ]
SUPFAMi SSF49464. SSF49464. 1 hit.
SSF49785. SSF49785. 1 hit.
PROSITEi PS00132. CARBOXYPEPT_ZN_1. 1 hit.
PS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation."
    Layne M.D., Endege W.O., Jain M.K., Yet S.-F., Hsieh C.-M., Chin M.T., Perrella M.A., Blanar M.A., Haber E., Lee M.-E.
    J. Biol. Chem. 273:15654-15660(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Aortic smooth muscle.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
  3. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLU-1133.
    Tissue: Aortic endothelium.
  4. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  7. "A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line."
    Ohno I., Hashimoto J., Shimizu K., Takaoka K., Ochi T., Matsubara K., Okubo K.
    Biochem. Biophys. Res. Commun. 228:411-414(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 314-1158 (ISOFORM 1), TISSUE SPECIFICITY.
    Tissue: Cancellous bone.
  8. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
    Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
    J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-528 AND ASN-922.
    Tissue: Liver.

Entry informationi

Entry nameiAEBP1_HUMAN
AccessioniPrimary (citable) accession number: Q8IUX7
Secondary accession number(s): Q14113
, Q59ER7, Q6ZSC7, Q7KZ79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Peptidase families
    Classification of peptidase families and list of entries
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3