Q8IUR7 (ARMC8_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Armadillo repeat-containing protein 8

Gene names

Name:	ARMC8
ORF Names:	S863-2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	673 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Contains 14 ARM repeats.
Sequence caution	The sequence BAA91861.1 differs from that shown. Reason: Frameshift at position 468. The sequence BAA91959.1 differs from that shown. Reason: Intron retention. The sequence CAB46423.1 differs from that shown. Reason: Intron retention.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Domain	Repeat
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8IUR7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8IUR7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     2-15: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q8IUR7-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-42: Missing.

Note: No experimental confirmation available.

Isoform 6 (identifier: Q8IUR7-6)

The sequence of this isoform differs from the canonical sequence as follows:
     2-15: Missing.
     379-399: IIETENMMDRIVTGLSESSVK → VSLGEGRPPVLTASRQGVTST
     400-673: Missing.

Isoform 7 (identifier: Q8IUR7-7)

The sequence of this isoform differs from the canonical sequence as follows:
     146-176: Missing.

Note: No experimental confirmation available.

Isoform 8 (identifier: Q8IUR7-8)

The sequence of this isoform differs from the canonical sequence as follows:
     280-346: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.6
	Chain	2 – 673	672	Armadillo repeat-containing protein 8		PRO_0000284408
Regions
	Repeat	51 – 92	42	ARM 1
	Repeat	95 – 134	40	ARM 2
	Repeat	138 – 176	39	ARM 3
	Repeat	178 – 217	40	ARM 4
	Repeat	224 – 265	42	ARM 5
	Repeat	269 – 309	41	ARM 6
	Repeat	313 – 352	40	ARM 7
	Repeat	374 – 413	40	ARM 8
	Repeat	416 – 455	40	ARM 9
	Repeat	458 – 497	40	ARM 10
	Repeat	501 – 540	40	ARM 11
	Repeat	543 – 585	43	ARM 12
	Repeat	588 – 627	40	ARM 13
	Repeat	634 – 673	40	ARM 14
Amino acid modifications
	Modified residue	2	1	N-acetylalanine Ref.6
	Modified residue	391	1	Phosphothreonine By similarity
Natural variations
	Alternative sequence	1 – 42	42	Missing in isoform 3.		VSP_024512
	Alternative sequence	2 – 15	14	Missing in isoform 2 and isoform 6.		VSP_024509
	Alternative sequence	146 – 176	31	Missing in isoform 7.		VSP_044774
	Alternative sequence	280 – 346	67	Missing in isoform 8.		VSP_045137
	Alternative sequence	379 – 399	21	IIETE…ESSVK → VSLGEGRPPVLTASRQGVTS T in isoform 6.		VSP_024513
	Alternative sequence	400 – 673	274	Missing in isoform 6.		VSP_024514
Experimental info
	Sequence conflict	78	1	E → G in BAA91861. Ref.2
	Sequence conflict	128	1	C → R in BAH12439. Ref.2
	Sequence conflict	231	1	V → A in AAH32661. Ref.5
	Sequence conflict	327	1	M → V in BAA91861. Ref.2
	Sequence conflict	397	1	S → N in BAA91959. Ref.2
	Sequence conflict	462	1	E → G in BAH12439. Ref.2
	Sequence conflict	495	1	M → I in BAH12439. Ref.2
	Sequence conflict	537	1	N → S in BAA91959. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified April 17, 2007. Version 2. Checksum: 726BAC0A373485E8	FASTA	673	75,509
	10 20 30 40 50 60 MACLLETPIR MSVLSEVTAS SRHYVDRLFD PDPQKVLQGV IDMKNAVIGN NKQKANLIVL 70 80 90 100 110 120 GAVPRLLYLL QQETSSTELK TECAVVLGSL AMGTENNVKS LLDCHIIPAL LQGLLSPDLK 130 140 150 160 170 180 FIEACLRCLR TIFTSPVTPE ELLYTDATVI PHLMALLSRS RYTQEYICQI FSHCCKGPDH 190 200 210 220 230 240 QTILFNHGAV QNIAHLLTSL SYKVRMQALK CFSVLAFENP QVSMTLVNVL VDGELLPQIF 250 260 270 280 290 300 VKMLQRDKPI EMQLTSAKCL TYMCRAGAIR TDDNCIVLKT LPCLVRMCSK ERLLEERVEG 310 320 330 340 350 360 AETLAYLIEP DVELQRIASI TDHLIAMLAD YFKYPSSVSA ITDIKRLDHD LKHAHELRQA 370 380 390 400 410 420 AFKLYASLGA NDEDIRKKII ETENMMDRIV TGLSESSVKV RLAAVRCLHS LSRSVQQLRT 430 440 450 460 470 480 SFQDHAVWKP LMKVLQNAPD EILVVASSML CNLLLEFSPS KEPILESGAV ELLCGLTQSE 490 500 510 520 530 540 NPALRVNGIW ALMNMAFQAE QKIKADILRS LSTEQLFRLL SDSDLNVLMK TLGLLRNLLS 550 560 570 580 590 600 TRPHIDKIMS THGKQIMQAV TLILEGEHNI EVKEQTLCIL ANIADGTTAK DLIMTNDDIL 610 620 630 640 650 660 QKIKYYMGHS HVKLQLAAMF CISNLIWNEE EGSQERQDKL RDMGIVDILH KLSQSPDSNL 670 CDKAKMALQQ YLA
	Isoform 2 [UniParc]. Checksum: 8A3314D9F0DF302F	FASTA	659	73,994
	10 20 30 40 50 60 MEVTASSRHY VDRLFDPDPQ KVLQGVIDMK NAVIGNNKQK ANLIVLGAVP RLLYLLQQET 70 80 90 100 110 120 SSTELKTECA VVLGSLAMGT ENNVKSLLDC HIIPALLQGL LSPDLKFIEA CLRCLRTIFT 130 140 150 160 170 180 SPVTPEELLY TDATVIPHLM ALLSRSRYTQ EYICQIFSHC CKGPDHQTIL FNHGAVQNIA 190 200 210 220 230 240 HLLTSLSYKV RMQALKCFSV LAFENPQVSM TLVNVLVDGE LLPQIFVKML QRDKPIEMQL 250 260 270 280 290 300 TSAKCLTYMC RAGAIRTDDN CIVLKTLPCL VRMCSKERLL EERVEGAETL AYLIEPDVEL 310 320 330 340 350 360 QRIASITDHL IAMLADYFKY PSSVSAITDI KRLDHDLKHA HELRQAAFKL YASLGANDED 370 380 390 400 410 420 IRKKIIETEN MMDRIVTGLS ESSVKVRLAA VRCLHSLSRS VQQLRTSFQD HAVWKPLMKV 430 440 450 460 470 480 LQNAPDEILV VASSMLCNLL LEFSPSKEPI LESGAVELLC GLTQSENPAL RVNGIWALMN 490 500 510 520 530 540 MAFQAEQKIK ADILRSLSTE QLFRLLSDSD LNVLMKTLGL LRNLLSTRPH IDKIMSTHGK 550 560 570 580 590 600 QIMQAVTLIL EGEHNIEVKE QTLCILANIA DGTTAKDLIM TNDDILQKIK YYMGHSHVKL 610 620 630 640 650 QLAAMFCISN LIWNEEEGSQ ERQDKLRDMG IVDILHKLSQ SPDSNLCDKA KMALQQYLA
	Isoform 3 [UniParc]. Checksum: 8DB486E356108D97	FASTA	631	70,796
	10 20 30 40 50 60 MKNAVIGNNK QKANLIVLGA VPRLLYLLQQ ETSSTELKTE CAVVLGSLAM GTENNVKSLL 70 80 90 100 110 120 DCHIIPALLQ GLLSPDLKFI EACLRCLRTI FTSPVTPEEL LYTDATVIPH LMALLSRSRY 130 140 150 160 170 180 TQEYICQIFS HCCKGPDHQT ILFNHGAVQN IAHLLTSLSY KVRMQALKCF SVLAFENPQV 190 200 210 220 230 240 SMTLVNVLVD GELLPQIFVK MLQRDKPIEM QLTSAKCLTY MCRAGAIRTD DNCIVLKTLP 250 260 270 280 290 300 CLVRMCSKER LLEERVEGAE TLAYLIEPDV ELQRIASITD HLIAMLADYF KYPSSVSAIT 310 320 330 340 350 360 DIKRLDHDLK HAHELRQAAF KLYASLGAND EDIRKKIIET ENMMDRIVTG LSESSVKVRL 370 380 390 400 410 420 AAVRCLHSLS RSVQQLRTSF QDHAVWKPLM KVLQNAPDEI LVVASSMLCN LLLEFSPSKE 430 440 450 460 470 480 PILESGAVEL LCGLTQSENP ALRVNGIWAL MNMAFQAEQK IKADILRSLS TEQLFRLLSD 490 500 510 520 530 540 SDLNVLMKTL GLLRNLLSTR PHIDKIMSTH GKQIMQAVTL ILEGEHNIEV KEQTLCILAN 550 560 570 580 590 600 IADGTTAKDL IMTNDDILQK IKYYMGHSHV KLQLAAMFCI SNLIWNEEEG SQERQDKLRD 610 620 630 MGIVDILHKL SQSPDSNLCD KAKMALQQYL A
	Isoform 6 [UniParc]. Checksum: BAE44225B08675A6	FASTA	385	42,984
	10 20 30 40 50 60 MEVTASSRHY VDRLFDPDPQ KVLQGVIDMK NAVIGNNKQK ANLIVLGAVP RLLYLLQQET 70 80 90 100 110 120 SSTELKTECA VVLGSLAMGT ENNVKSLLDC HIIPALLQGL LSPDLKFIEA CLRCLRTIFT 130 140 150 160 170 180 SPVTPEELLY TDATVIPHLM ALLSRSRYTQ EYICQIFSHC CKGPDHQTIL FNHGAVQNIA 190 200 210 220 230 240 HLLTSLSYKV RMQALKCFSV LAFENPQVSM TLVNVLVDGE LLPQIFVKML QRDKPIEMQL 250 260 270 280 290 300 TSAKCLTYMC RAGAIRTDDN CIVLKTLPCL VRMCSKERLL EERVEGAETL AYLIEPDVEL 310 320 330 340 350 360 QRIASITDHL IAMLADYFKY PSSVSAITDI KRLDHDLKHA HELRQAAFKL YASLGANDED 370 380 IRKKVSLGEG RPPVLTASRQ GVTST
	Isoform 7 [UniParc]. Checksum: C22F37EEF0B56B93	FASTA	642	71,899
	10 20 30 40 50 60 MACLLETPIR MSVLSEVTAS SRHYVDRLFD PDPQKVLQGV IDMKNAVIGN NKQKANLIVL 70 80 90 100 110 120 GAVPRLLYLL QQETSSTELK TECAVVLGSL AMGTENNVKS LLDCHIIPAL LQGLLSPDLK 130 140 150 160 170 180 FIEACLRCLR TIFTSPVTPE ELLYTGPDHQ TILFNHGAVQ NIAHLLTSLS YKVRMQALKC 190 200 210 220 230 240 FSVLAFENPQ VSMTLVNVLV DGELLPQIFV KMLQRDKPIE MQLTSAKCLT YMCRAGAIRT 250 260 270 280 290 300 DDNCIVLKTL PCLVRMCSKE RLLEERVEGA ETLAYLIEPD VELQRIASIT DHLIAMLADY 310 320 330 340 350 360 FKYPSSVSAI TDIKRLDHDL KHAHELRQAA FKLYASLGAN DEDIRKKIIE TENMMDRIVT 370 380 390 400 410 420 GLSESSVKVR LAAVRCLHSL SRSVQQLRTS FQDHAVWKPL MKVLQNAPDE ILVVASSMLC 430 440 450 460 470 480 NLLLEFSPSK EPILESGAVE LLCGLTQSEN PALRVNGIWA LMNMAFQAEQ KIKADILRSL 490 500 510 520 530 540 STEQLFRLLS DSDLNVLMKT LGLLRNLLST RPHIDKIMST HGKQIMQAVT LILEGEHNIE 550 560 570 580 590 600 VKEQTLCILA NIADGTTAKD LIMTNDDILQ KIKYYMGHSH VKLQLAAMFC ISNLIWNEEE 610 620 630 640 GSQERQDKLR DMGIVDILHK LSQSPDSNLC DKAKMALQQY LA
	Isoform 8 [UniParc]. Checksum: C5946E9DC52A4AB9	FASTA	606	67,900
	10 20 30 40 50 60 MACLLETPIR MSVLSEVTAS SRHYVDRLFD PDPQKVLQGV IDMKNAVIGN NKQKANLIVL 70 80 90 100 110 120 GAVPRLLYLL QQETSSTELK TECAVVLGSL AMGTENNVKS LLDCHIIPAL LQGLLSPDLK 130 140 150 160 170 180 FIEACLRCLR TIFTSPVTPE ELLYTDATVI PHLMALLSRS RYTQEYICQI FSHCCKGPDH 190 200 210 220 230 240 QTILFNHGAV QNIAHLLTSL SYKVRMQALK CFSVLAFENP QVSMTLVNVL VDGELLPQIF 250 260 270 280 290 300 VKMLQRDKPI EMQLTSAKCL TYMCRAGAIR TDDNCIVLKL DHDLKHAHEL RQAAFKLYAS 310 320 330 340 350 360 LGANDEDIRK KIIETENMMD RIVTGLSESS VKVRLAAVRC LHSLSRSVQQ LRTSFQDHAV 370 380 390 400 410 420 WKPLMKVLQN APDEILVVAS SMLCNLLLEF SPSKEPILES GAVELLCGLT QSENPALRVN 430 440 450 460 470 480 GIWALMNMAF QAEQKIKADI LRSLSTEQLF RLLSDSDLNV LMKTLGLLRN LLSTRPHIDK 490 500 510 520 530 540 IMSTHGKQIM QAVTLILEGE HNIEVKEQTL CILANIADGT TAKDLIMTND DILQKIKYYM 550 560 570 580 590 600 GHSHVKLQLA AMFCISNLIW NEEEGSQERQ DKLRDMGIVD ILHKLSQSPD SNLCDKAKMA LQQYLA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Liu B., Zhao B., Wang X.Y., Xu Y.Y., Liu Y.Q., Song L., Ye J., Sheng H., Gao Y., Zhang C.L., Wei Y.J., Zhang J., Song L., Jiang Y.X., Zhao Z.W., Ding J.F., Liu L.S., Gao R.L. , Wu Q.Y., Qiang B.Q., Yuan J.G., Liew C.C., Zhao M.S., Hui R.T. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6). Tissue: Aorta.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 6; 7 AND 8), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 243-673 (ISOFORMS 1/2/3). Tissue: Cerebellum, Placenta, Teratocarcinoma and Tongue.
[3]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 6). Tissue: Brain, Lung and Uterus.
[6]	Bienvenut W.V., Lempens A., Norman J.C. Submitted (OCT-2009) to UniProtKB Cited for: PROTEIN SEQUENCE OF 2-22; 36-44; 55-65; 247-258; 364-376; 379-399; 510-530; 591-602 AND 642-651, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, MASS SPECTROMETRY. Tissue: Ovarian carcinoma.
[7]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 432-673 (ISOFORMS 1/2/3). Tissue: Testis.
[8]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF109184 mRNA. Translation: AAQ13493.1. AK001721 mRNA. Translation: BAA91861.1. Frameshift. AK001882 mRNA. Translation: BAA91959.1. Sequence problems. AK289577 mRNA. Translation: BAF82266.1. AK296757 mRNA. Translation: BAH12427.1. AK296837 mRNA. Translation: BAH12439.1. AC022337 Genomic DNA. No translation available. AC068777 Genomic DNA. No translation available. CH471052 Genomic DNA. Translation: EAW79076.1. CH471052 Genomic DNA. Translation: EAW79075.1. CH471052 Genomic DNA. Translation: EAW79079.1. BC013424 mRNA. Translation: AAH13424.1. BC032661 mRNA. Translation: AAH32661.1. BC041699 mRNA. Translation: AAH41699.1. AL096748 mRNA. Translation: CAB46423.1. Sequence problems.
IPI	IPI00396379. IPI00794568. IPI00795553. IPI00947550.
PIR	T12513.
RefSeq	NP_001253970.1. NM_001267041.1. NP_001253971.1. NM_001267042.1. NP_054873.2. NM_014154.3. NP_056211.2. NM_015396.4. NP_998819.1. NM_213654.2.
UniGene	Hs.740399.
3D structure databases
ProteinModelPortal	Q8IUR7.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8IUR7. 1 interaction.
STRING	9606.ENSP00000351221.
PTM databases
PhosphoSite	Q8IUR7.
Polymorphism databases
DMDM	145558852.
Proteomic databases
PaxDb	Q8IUR7.
PRIDE	Q8IUR7.
Protocols and materials databases
DNASU	25852.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000358441; ENSP00000351221; ENSG00000114098. ENST00000461822; ENSP00000420706; ENSG00000114098. ENST00000469044; ENSP00000419413; ENSG00000114098. ENST00000471453; ENSP00000420440; ENSG00000114098. ENST00000481646; ENSP00000420333; ENSG00000114098. ENST00000491704; ENSP00000417304; ENSG00000114098. ENST00000538260; ENSP00000441592; ENSG00000114098.
GeneID	25852.
KEGG	hsa:25852.
UCSC	uc003erw.3. human. uc003esa.1. human. uc003esb.1. human.
Organism-specific databases
CTD	25852.
GeneCards	GC03P137906.
H-InvDB	HIX0003713.
HGNC	HGNC:24999. ARMC8.
HPA	HPA036996.
neXtProt	NX_Q8IUR7.
PharmGKB	PA134984953.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG307826.
HOVERGEN	HBG106422.
InParanoid	Q8IUR7.
OMA	HSNVKLQ.
OrthoDB	EOG4GMTWD.
Gene expression databases
ArrayExpress	Q8IUR7.
Bgee	Q8IUR7.
CleanEx	HS_ARMC8.
Genevestigator	Q8IUR7.
Family and domain databases
Gene3D	1.25.10.10. 3 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000225. Armadillo. [Graphical view]
Pfam	PF00514. Arm. 1 hit. [Graphical view]
SMART	SM00185. ARM. 7 hits. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
PROSITE	PS50176. ARM_REPEAT. 1 hit. PS50077. HEAT_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ARMC8. human.
GenomeRNAi	25852.
NextBio	47196.

Entry information

Entry name

ARMC8_HUMAN

Accession

Primary (citable) accession number: Q8IUR7
Secondary accession number(s): A8K0L2 , B7Z441, B7Z453, D3DNE6, F5GWK4, Q6PIL2, Q96D19, Q96HZ5, Q9NV02, Q9NV94, Q9Y4R9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	May 1, 2013
This is version 92 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.