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Protein
Submitted name:

ADH6 protein

Gene

ADH6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ADH6 proteinImported
Submitted name:
Alcohol dehydrogenase 6Imported
Gene namesi
Name:ADH6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000172955.17
HGNCiHGNC:255 ADH6

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172955
PharmGKBiPA24576

PTM / Processingi

Proteomic databases

PRIDEiQ8IUN7

Expressioni

Gene expression databases

BgeeiENSG00000172955
ExpressionAtlasiQ8IUN7 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ8IUN7, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 160ADH_NInterPro annotationAdd BLAST126
Domaini203 – 272ADH_zinc_NInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the zinc-containing alcohol dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0022 Eukaryota
COG1062 LUCA
GeneTreeiENSGT00430000030800
HOGENOMiHOG000294674
HOVERGENiHBG000195
KOiK13952

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00059 ADH_ZINC, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IUN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTGQVIRC KAAILWKPGA PFSIEEVEVA PPKAKEVRIK VVATGLCGTE
60 70 80 90 100
MKVLGSKHLD LLYPTILGHE GAGIVESIGE GVSTVKPGDK VITLFLPQCG
110 120 130 140 150
ECTSCLNSEG NFCIQFKQSK TQLMSDGTSR FTCKGKSIYH FGNTSTFCEY
160 170 180 190 200
TVIKEISVAK IDAVAPLEKV CLISCGFSTG FGAAINTAKV TPGSTCAVFG
210 220 230 240 250
LGGVGLSVVM GCKAAGAARI IGVDVNKEKF KKAQELGATE CLNPQDLKKP
260 270 280 290
IQEVLFDMTD AGIDFCFEAI GNLDVLAGRA DSTSLNWLLI IWQRS
Length:295
Mass (Da):31,299
Last modified:March 1, 2003 - v1
Checksum:iDE4720D0B3B91962
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002026 Genomic DNA No translation available.
KF457794 Genomic DNA No translation available.
BC039065 mRNA Translation: AAH39065.1
RefSeqiNP_000663.1, NM_000672.3
NP_001095940.1, NM_001102470.1
UniGeneiHs.586161

Genome annotation databases

EnsembliENST00000394897; ENSP00000378358; ENSG00000172955
GeneIDi130
KEGGihsa:130
UCSCiuc010ile.4 human

Similar proteinsi

Entry informationi

Entry nameiQ8IUN7_HUMAN
AccessioniPrimary (citable) accession number: Q8IUN7
Secondary accession number(s): E9PBI1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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