Q8IUA4 (Q8IUA4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RNT4 EMBL AAM64244.1

Submitted name:
RTN4 isoform Aa EMBL AAM64249.1
Submitted name:
RTN4 isoform Ab EMBL AAM64250.1
Submitted name:
RTN4 isoform D EMBL AAM64251.1
Submitted name:
RTN4 isoform E EMBL AAM64252.1
Submitted name:
RTN4 isoform F EMBL AAM64253.1
Submitted name:
RTN4 isoform G EMBL AAM64254.1
Submitted name:
Reticulon 4, isoform CRA_c EMBL EAX00117.1
Submitted name:
Reticulon 4, isoform CRA_f EMBL EAX00122.1

Gene names

Name:	RTN4 EMBL AAM64244.1
ORF Names:	hCG_1784307 EMBL EAX00117.1

Organism

Homo sapiens (Human) EMBL AAM64244.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	986 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	986	1	EMBL EAX00117.1

Sequences

	Sequence		Length	Mass (Da)
	Q8IUA4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 0CDE8F647036415A	FASTA	986	108,450
	10 20 30 40 50 60 MDLKEQPGNT ISAGQEDFPS VLLETAASLP SLSPLSAASF KEHEYLGNLS TVLPTEGTLQ 70 80 90 100 110 120 ENVSEASKEV SEKAKTLLID RDLTEFSELE YSEMGSSFSV SPKAESAVIV ANPREEIIVK 130 140 150 160 170 180 NKDEEEKLVS NNILHNQQEL PTALTKLVKE DEVVSSEKAK DSFNEKRVAV EAPMREEYAD 190 200 210 220 230 240 FKPFERVWEV KDSKEDSDML AAGGKIESNL ESKVDKKCFA DSLEQTNHEK DSESSNDDTS 250 260 270 280 290 300 FPSTPEGIKD RSGAYITCAP FNPAATESIA TNIFPLLGDP TSENKTDEKK IEEKKAQIVT 310 320 330 340 350 360 EKNTSTKTSN PFLVAAQDSE TDYVTTDNLT KVTEEVVANM PEGLTPDLVQ EACESELNEV 370 380 390 400 410 420 TGTKIAYETK MDLVQTSEVM QESLYPAAQL CPSFEESEAT PSPVLPDIVM EAPLNSAVPS 430 440 450 460 470 480 AGASVIQPSS SPLEASSVNY ESIKHEPENP PPYEEAMSVS LKKVSGIKEE IKEPENINAA 490 500 510 520 530 540 LQETEAPYIS IACDLIKETK LSAEPAPDFS DYSEMAKVEQ PVPDHSELVE DSSPDSEPVD 550 560 570 580 590 600 LFSDDSIPDV PQKQDETVML VKESLTETSF ESMIEYENKE KLSALPPEGG KPYLESFKLS 610 620 630 640 650 660 LDNTKDTLLP DEVSTLSKKE KIPLQMEELS TAVYSNDDLF ISKEAQIRET ETFSDSSPIE 670 680 690 700 710 720 IIDEFPTLIS SKTDSFSKLA REYTDLEVSH KSEIANAPDG AGSLPCTELP HDLSLKNIQP 730 740 750 760 770 780 KVEEKISFSD DFSKNGSATS KVLLLPPDVS ALATQAEIES IVKPKVLVKE AEKKLPSDTE 790 800 810 820 830 840 KEDRSPSAIF SAELSKTSVV DLLYWRDIKK TGVVFGASLF LLLSLTVFSI VSVTAYIALA 850 860 870 880 890 900 LLSVTISFRI YKGVIQAIQK SDEGHPFRAY LESEVAISEE LVQKYSNSAL GHVNCTIKEL 910 920 930 940 950 960 RRLFLVDDLV DSLKFAVLMW VFTYVGALFN GLTLLILALI SLFSVPVIYE RHQAQIDHYL 970 980 GLANKNVKDA MAKIQAKIPG LKRKAE

References

[1]	"Genomic structure and functional characterisation of the promoters of human and mouse nogo/rtn4." Oertle T., Huber C., van der Putten H., Schwab M.E. J. Mol. Biol. 325:299-323(2003) [PubMed: 12488097] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAM64249.1.
[2]	"The sequence of the human genome." Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H. , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X. Science 291:1304-1351(2001) [PubMed: 11181995] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Van der Putten H. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAM64249.1.
[4]	Oertle T., Schwab M.E. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL AAM64249.1.
[5]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY102285 Genomic DNA. Translation: AAM64244.1. AY123245 mRNA. Translation: AAM64249.1. AY123246 mRNA. Translation: AAM64250.1. AY123247 mRNA. Translation: AAM64251.1. AY123248 mRNA. Translation: AAM64252.1. AY123249 mRNA. Translation: AAM64253.1. AY123250 mRNA. Translation: AAM64254.1. CH471053 Genomic DNA. Translation: EAX00117.1. CH471053 Genomic DNA. Translation: EAX00122.1. CH471053 Genomic DNA. Translation: EAX00123.1. CH471053 Genomic DNA. Translation: EAX00124.1. CH471053 Genomic DNA. Translation: EAX00125.1. CH471053 Genomic DNA. Translation: EAX00127.1. CH471053 Genomic DNA. Translation: EAX00130.1.
IPI	IPI00894213.
RefSeq	NP_065393.1. NM_020532.4. NP_722550.1. NM_153828.2. NP_997403.1. NM_207520.1. NP_997404.1. NM_207521.1.
UniGene	Hs.727710.
3D structure databases
ProteinModelPortal	Q8IUA4.
SMR	Q8IUA4. Positions 849-908.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8IUA4.
Proteomic databases
PRIDE	Q8IUA4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	57142.
KEGG	hsa:57142.
UCSC	uc002ryd.1. human.
Organism-specific databases
CTD	57142.
Phylogenomic databases
GeneTree	ENSGT00390000009934.
HOVERGEN	HBG023134.
Gene expression databases
ArrayExpress	Q8IUA4.
Bgee	Q8IUA4.
Family and domain databases
InterPro	IPR003388. Reticulon. [Graphical view]
PANTHER	PTHR10994. Reticulon. 1 hit.
Pfam	PF02453. Reticulon. 1 hit. [Graphical view]
PROSITE	PS50845. RETICULON. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	63075.

Entry information

Entry name

Q8IUA4_HUMAN

Accession

Primary (citable) accession number: Q8IUA4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.