Q8IU77 (Q8IU77_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Breast and ovarian cancer susceptibility protein EMBL AAN61426.1

Gene names

Name:

BRCA2 EMBL AAN61426.1

Organism

Homo sapiens (Human) EMBL AAN61426.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	35 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Inferred from electronic annotation. Source: Compara brain development Inferred from electronic annotation. Source: Compara cell aging Inferred from electronic annotation. Source: Compara chromosome organization Inferred from electronic annotation. Source: Compara double-strand break repair via homologous recombination Inferred from electronic annotation. Source: Compara female gonad development Inferred from electronic annotation. Source: Compara hemopoiesis Inferred from electronic annotation. Source: Compara inner cell mass cell proliferation Inferred from electronic annotation. Source: Compara intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Inferred from electronic annotation. Source: Compara male meiosis I Inferred from electronic annotation. Source: Compara oocyte maturation Inferred from electronic annotation. Source: Compara positive regulation of mitotic cell cycle Inferred from electronic annotation. Source: Compara regulation of cytokinesis Inferred from electronic annotation. Source: Compara replication fork protection Inferred from electronic annotation. Source: Compara response to UV-C Inferred from electronic annotation. Source: Compara response to X-ray Inferred from electronic annotation. Source: Compara response to gamma radiation Inferred from electronic annotation. Source: Compara spermatogenesis Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAN61426.1
	Non-terminal residue	35	1	EMBL AAN61426.1

Sequences

	Sequence		Length	Mass (Da)
	Q8IU77 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 8ED0CCB929AA82FA	FASTA	35	3,943
	10 20 30 RNVPNSRHKS LRTVKTKMDQ ADDVSCPLLN SCLSE

References

[1]	"BRCA2 germline mutations in Indian breast cancer families." Valarmathi M.T., Agarwal A., Deo S.S.V., Shukla N.K., Das S.N. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF507079 Genomic DNA. Translation: AAN61426.1. AF507080 Genomic DNA. Translation: AAN61427.1. AF507081 Genomic DNA. Translation: AAN61428.1. AF507082 Genomic DNA. Translation: AAN61429.1. AF507083 Genomic DNA. Translation: AAN61430.1. AF507084 Genomic DNA. Translation: AAN61431.1. AF507085 Genomic DNA. Translation: AAN61432.1. AF507086 Genomic DNA. Translation: AAN61433.1.
IPI	IPI00977860.
UniGene	Hs.34012.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8IU77.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q8IU77.
Bgee	Q8IU77.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

Q8IU77_HUMAN

Accession

Primary (citable) accession number: Q8IU77

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.