SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8IR69

- Q8IR69_DROME

UniProt

Q8IR69 - Q8IR69_DROME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

HDAC4, isoform B

Gene
HDAC4, CG1770, Dmel_CG1770
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. histone deacetylase activity Source: FlyBase

GO - Biological processi

  1. histone deacetylation Source: GOC
  2. regulation of transcription, DNA-templated Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotationsImported

Names & Taxonomyi

Protein namesi
Submitted name:
HDAC4, isoform BImported (EC:3.5.1.-Imported)
Submitted name:
HDAC4, isoform HImported (EC:3.5.1.-Imported)
Gene namesi
Name:HDAC4Imported
ORF Names:CG1770Imported, Dmel_CG1770Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome X

Organism-specific databases

FlyBaseiFBgn0041210. HDAC4.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: FlyBase
  2. histone deacetylase complex Source: InterPro
  3. nucleus Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8IR69.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062809.
InParanoidiQ8IR69.
KOiK11406.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037911. HDAC_II_euk. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

Q8IR69-1 [UniParc]FASTAAdd to Basket

« Hide

MELEHKLQLE HKYQFAVNSH GAFQELRNES MVTAAAAAVA QEQHRQQLHQ     50
QQQQHQQQQQ QQQHQQQQQQ QQARGRDGMK LKQNCSANAS PEVKQILNCF 100
ILSRKSQAAA SNGTTTTSPY RNRGVVKSSS GESLPAGTVT SAHPYKIPQP 150
PPSLLKYESD FPLRKTASEP NLLKIRLKQS VIERKARIGG PAGARRHERL 200
LQAAQRRQQK NSVLTNCNST PDSGPNSPPS AAALAVGVVG SRGSPTSAPI 250
QEENEEGSQY QPGQRSSIND LPLFSSPSLP NISLGRPHLP NSAQAHAQVN 300
AQVAAQAQAQ AQAQAQAHAM FAALAAAQGG CGQPGYYNPL GMAFVGRQPA 350
PLAMIPATGI APQQPSPVVR SASATSTSSS QASLVGDVAP PQAHAASTIL 400
PSSSSYMQQL GSVAGSGVNL HAAAVAAAAA AAAAAGSLPP TNSHGHGHGS 450
HAHPHPHAHG HGHGHGHGIY AGHQHNVPIT DAQVAQVHLH KQGHRPLGRT 500
QSAPLPLGHP MLTGAVQLNV VQTHYENSEA ERQAYEHQVV NQKVRQTVLT 550
RSGAAAAAAA AAGVSVVREA QLKEEDDDSA AEVMDLTDKK KPPKTVLTST 600
IATSTSQNLP EALAAAAAAA AYRAPHNASS NSASATKSGI KLRDQEYLQQ 650
QREQLLLLQQ EEELAKSLMR PLSRTLSSPL VPLGPHGLSQ IPDTGQQPAP 700
IATSSSADHI PPVNLSLPHR QHRQLMSTLY ASQLRNHQPS ASGSPPHKVT 750
TGLAYDPLML KHSCICGDNA QHPEHSGRLQ SVWARLNETD LVKRCDRLRA 800
RKATQEELQT VHTEAHAMLF GSNQCQLSRP KLENTLSASF VRLSCGGLGV 850
DLDTTWNEHH TATAARMAAG CVIDLALKTA KGDLRNGFAV VRPPGHHAEA 900
NLAMGFCFFN SIAIAAKLLR QRMPEVRRIL IVDWDVHHGN GTQQAFYQSP 950
DILYLSIHRH DDGNFFPGTG GPTECGSGAG LGFNVNISWS GALNPPLGDA 1000
EYIAAFRTVV MPIARSFNPD IVLVSSGFDA ATGHPAPLGG YHVSPACFGF 1050
MTRELLQLAN GKVVLALEGG YDLAAICDSA QECVRALLGD PAAPIAKAEL 1100
ERPPCQNAIN TLQKTIAIQQ THWPCVRMLE HTVGLSALET LKVEHDESET 1150
INAMAGLSMQ SMHRTLSRDD SEEPMDQDET K 1181
Length:1,181
Mass (Da):126,044
Last modified:March 1, 2003 - v1
Checksum:iAD451B406E8719B1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014298 Genomic DNA. Translation: AAN09318.1.
AE014298 Genomic DNA. Translation: AGB95350.1.
RefSeqiNP_001259508.1. NM_001272579.1.
NP_727682.1. NM_167356.3.
UniGeneiDm.6484.

Genome annotation databases

EnsemblMetazoaiFBtr0073798; FBpp0073629; FBgn0041210.
FBtr0333332; FBpp0305524; FBgn0041210.
GeneIDi32278.
KEGGidme:Dmel_CG1770.
UCSCiCG1770-RB. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014298 Genomic DNA. Translation: AAN09318.1 .
AE014298 Genomic DNA. Translation: AGB95350.1 .
RefSeqi NP_001259508.1. NM_001272579.1.
NP_727682.1. NM_167356.3.
UniGenei Dm.6484.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0073798 ; FBpp0073629 ; FBgn0041210 .
FBtr0333332 ; FBpp0305524 ; FBgn0041210 .
GeneIDi 32278.
KEGGi dme:Dmel_CG1770.
UCSCi CG1770-RB. d. melanogaster.

Organism-specific databases

CTDi 9759.
FlyBasei FBgn0041210. HDAC4.

Phylogenomic databases

GeneTreei ENSGT00530000062809.
InParanoidi Q8IR69.
KOi K11406.

Miscellaneous databases

GenomeRNAii 32278.
NextBioi 777716.

Gene expression databases

Bgeei Q8IR69.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037911. HDAC_II_euk. 1 hit.
PRINTSi PR01270. HDASUPER.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  3. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  7. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  8. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  11. FlyBase
    Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8IR69_DROME
AccessioniPrimary (citable) accession number: Q8IR69
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi